LOCUS       NM_001285893            5027 bp    mRNA    linear   ROD 31-MAY-2024
DEFINITION  Mus musculus VPS8 CORVET complex subunit (Vps8), transcript variant
            1, mRNA.
ACCESSION   NM_001285893
VERSION     NM_001285893.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5027)
  AUTHORS   Suto,J.I. and Kojima,M.
  TITLE     Low pup survival rate is associated with maternal Naq3 genotype and
            hypothalamic Vps8 expression levels in mice
  JOURNAL   Congenit Anom (Kyoto) 61 (3), 97-100 (2021)
   PUBMED   33289187
  REMARK    GeneRIF: Low pup survival rate is associated with maternal Naq3
            genotype and hypothalamic Vps8 expression levels in mice.
REFERENCE   2  (bases 1 to 5027)
  AUTHORS   Perini,E.D., Schaefer,R., Stoter,M., Kalaidzidis,Y. and Zerial,M.
  TITLE     Mammalian CORVET is required for fusion and conversion of distinct
            early endosome subpopulations
  JOURNAL   Traffic 15 (12), 1366-1389 (2014)
   PUBMED   25266290
REFERENCE   3  (bases 1 to 5027)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC164549.4, BC055323.1 and AC130214.4.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC055323.1, SRR9219380.85507.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-83                AC164549.4         79827-79909
            84-5018             BC055323.1         1-4935
            5019-5027           AC130214.4         41979-41987
FEATURES             Location/Qualifiers
     source          1..5027
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 12.69 cM"
     gene            1..5027
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /note="VPS8 CORVET complex subunit"
                     /db_xref="GeneID:209018"
                     /db_xref="MGI:MGI:2146407"
     exon            1..108
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            109..485
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     CDS             333..4616
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /note="isoform 1 is encoded by transcript variant 1;
                     vacuolar protein sorting-associated protein 8 homolog;
                     vacuolar protein sorting 8 homolog"
                     /codon_start=1
                     /product="vacuolar protein sorting-associated protein 8
                     homolog isoform 1"
                     /protein_id="NP_001272822.1"
                     /db_xref="CCDS:CCDS70701.1"
                     /db_xref="GeneID:209018"
                     /db_xref="MGI:MGI:2146407"
                     /translation="METEPDQEHLDQNPCARTVEEELSKSFNLEASLSKFSCLDLDKE
                     LEFRSDLIDDKEFDIPQVDTPPTLESILNETDDEDESFVLEDPTLLNVDTIDSHSYDT
                     SSVASSDSGDRANLKRKKKLPDSFSLHGSVMRHSLLKGISAQIVSAADKVDAGLPTAI
                     AVSSLIAVGTSHGLALIFDQNQALRLCLGSTSVGGQYGAISALSINNDCSRLLCGFAK
                     GQITMWDLASGKLLRSITDAHPPGTAILHIKFTDDPTLAICNDSGGSVFELTFKRVMG
                     VRTCESRCLFSGSKGEVCCIEPLHSKPELKDHPITQFSLLAMASLTKILVIGLKPSLK
                     VWMTFPYGRMDPSSVPLLAWHFVAVNNSVNPMLAFCRGDMVHFLLVKRDESGAIHVTK
                     QKHLHLYYDLINFTWINSRTVVLLDSVEKLHVIDRQTQEELETMEISEVQLVYNSSHF
                     KSLATGGNVSQALALVGEKACYQSISSYGGQIFYLGTKSVYVMMLRSWRERMDHLLKQ
                     DCLTEALALAWSFHEGKAKAVVGLSGDVSKRKAVVADRMVEILFHYADRALKKCPDQG
                     KIQVMEQHFQDTVPVIVDYCLLLQRKDLLFGQMYDKLSENSVAKGVFLECLEPYILSD
                     KLVGITPQVMKDLIVHFQDKKLLENVEALIVHMDITSLDIQQVVLMCWENRLYDAMVY
                     VYNRGMNEFISPMEKLFKVIAPPLNAGKTLTDEQVVMGNKLLVYISCCLAGRAYPLGD
                     IPEDLVPLVKNQVFEFLIRLHSVEASSEEEVYPYVRTLLHFDTREFLNVLALTFEDFK
                     NDKQAVEYQQRIVDILLKVMVENSDFTPSQVGCLFTFLARQLAKPDNTLFVNRTLFDQ
                     VLEFLCSPDDDSRHSERQQVLLELLQAGGIVQFEESRLIRMAEKAEFYQICEFMYERE
                     HQYDKIIDCYLHDPLREEEVFNYIHNILSIPGHSAEEKQSVWQKAMNHMEELVSLKPC
                     KAAELVATHFSEQIEVVIGQLQNQLLLFKFLRSLLDPREGVHVNQELLQIPPHITEQF
                     IELLCQFSPDQVIQTLQVLECYRLEETIQITQKYQLHEVTAYLLEKKGDAHGAFLLLL
                     ERLQSRLQEMTRQDENTKEDILLKGVEDTMVETIALCQRNSQNLNQQQREALWFPLLE
                     AMMTPQKLSSSAAAPHPHCEALKSLTMQVLNSMAAFIALPSILQRILQDPIYGKGKLG
                     EIQGLILGMLDTFNYEQTLLETTASLLNQDLHWSLCNLRASVSRGLNPKQDYCSICLQ
                     QYKRRQEMADEIIVFSCGHLYHSFCLQSKECTLEVEGQTRWACHKCSSSNKAGKLSEN
                     PSENKKGRITSSQVKMSPSYHQSKGDPPARKANSEPVLDPQQMQAFDQLCRLYRGSSR
                     LALLTELSQNRGGDSCRPFAGPQSGPAFNSVFQKENFQLQLAPPPVAED"
     exon            486..554
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            555..685
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            686..779
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            780..812
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            813..867
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            868..992
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            993..1079
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            1080..1147
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            1148..1301
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            1302..1361
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            1362..1469
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            1470..1550
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            1551..1721
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            1722..1796
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            1797..1832
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            1833..1923
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            1924..1970
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            1971..2060
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            2061..2107
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            2108..2330
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            2331..2420
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            2421..2472
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            2473..2515
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            2516..2588
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            2589..2708
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            2709..2780
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            2781..2900
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            2901..2957
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            2958..3040
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            3041..3125
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            3126..3224
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            3225..3314
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            3315..3361
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            3362..3509
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            3510..3599
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            3600..3642
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            3643..3746
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            3747..3831
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            3832..3914
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            3915..3995
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            3996..4165
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            4166..4331
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            4332..4385
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            4386..4466
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     exon            4467..5027
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4995..5000
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /note="hexamer: AATAAA"
     polyA_site      5026
                     /gene="Vps8"
                     /gene_synonym="mKIAA0804"
                     /note="major polyA site"
ORIGIN      
        1 gggaagagag cggaagcgcg cccgccagct gccgagactg cgcgtgcgtg ggctggcctc
       61 cgcggggtca cgtgtgctgg ggtcccgtca aggcagacgc cggctcagga acccttcagc
      121 cacatcctac tctccacccc tttctttttg cctgcaaaca gatgaccaag tggaatctca
      181 tcaagggtgt ctctgaaatg tccagctgag aagatgtcta ggtaacacct gcctccctac
      241 caaagagatc atcgtttgga tctctgcaat ccaaggccaa aagcaagaaa cagttgcaag
      301 gggttggttg aattcagcca tcgaaagcaa atatggaaac tgaaccagac caggagcatt
      361 tggaccagaa cccgtgcgcc aggactgtgg aagaagagtt gagcaagtct tttaatttag
      421 aagcttccct ttcaaaattc tcttgcctag atctggataa ggagctggag ttcagaagtg
      481 acctgatcga tgacaaggag tttgatattc ctcaggtgga tacccctcca actctggaaa
      541 gcattcttaa tgagacggac gatgaagatg agtctttcgt tctggaggac cctaccttgt
      601 taaacgttga caccatcgac tctcactctt acgatacctc atctgtggcg agctcagaca
      661 gcggcgacag ggccaaccta aagaggaaga agaagttgcc ggactctttc tcgctgcatg
      721 ggtcggttat gcgacattca cttctaaagg ggatatctgc acagatcgtg tccgcagccg
      781 acaaagtaga tgctggcttg cctacagcaa ttgccgtgtc cagtctgata gcggtgggaa
      841 cgtctcacgg actggcttta atatttgatc agaatcaagc actgcggctc tgcctgggta
      901 gcaccagtgt tggagggcag tatggagcca tctctgccct cagcatcaac aatgactgct
      961 caagacttct ttgtggcttt gctaaagggc agatcaccat gtgggatttg gccagtggaa
     1021 aacttctcag atcaataaca gatgctcatc ctccagggac cgcaatcttg cacatcaagt
     1081 tcacagatga tccaactctt gcgatttgca acgacagtgg aggctctgtt tttgaactaa
     1141 catttaagag agtgatgggc gtgcgaacgt gtgagtctcg gtgcctattc agcggctcca
     1201 agggtgaggt ctgctgcatc gagccgctgc actcaaagcc cgagctgaaa gaccatccca
     1261 tcacgcagtt ctcactgctg gccatggcgt ccttaacaaa gatattggtc attgggttga
     1321 aaccatccct gaaagtgtgg atgactttcc cctatggacg gatggatcct tccagtgttc
     1381 cgctgctggc ctggcacttc gtggcagtga ataactctgt gaatcccatg ctcgccttct
     1441 gcagaggcga catggttcac tttctcctgg ttaagagaga tgagtcgggc gcaatacacg
     1501 tcaccaagca aaagcacctt cacctgtact atgacctgat caacttcact tggatcaact
     1561 cgcgcacagt cgtgctttta gacagcgtgg agaagctgca cgtgattgat cggcagacgc
     1621 aggaggaact ggagacaatg gagatctcgg aagtccagct ggtctacaac agcagccact
     1681 tcaagtcatt ggccacggga ggaaatgtta gccaggccct ggctttggtt ggagagaagg
     1741 cttgctacca atccatcagt agctatggag gacagatctt ctatctgggg accaagtctg
     1801 tgtacgtgat gatgctgaga agctggaggg agaggatgga ccatctcctg aaacaggatt
     1861 gccttacgga agccttggcc ctcgcgtggt cttttcatga aggaaaggca aaagcagtag
     1921 tggggctatc gggggatgtc agcaagagga aggctgttgt tgctgatcgg atggtagaga
     1981 tcctgttcca ttatgcagat cgggctctga aaaagtgccc ggaccagggg aaaatccaag
     2041 tgatggagca acactttcag gatacggtgc cagtcatagt ggactactgc cttctgctcc
     2101 agcgaaagga tcttctattt ggtcaaatgt acgacaaatt aagtgaaaat tccgtcgcaa
     2161 aaggcgtgtt tttggagtgc cttgagccat atatcttaag tgataaactg gtggggatta
     2221 ctccccaggt catgaaggac ttaattgttc atttccaaga taaaaaactg ctggagaatg
     2281 tggaagccct cattgtccac atggacatca ccagcctcga cattcagcag gtggtcctca
     2341 tgtgttggga gaatcgtctg tatgacgcca tggtctatgt ctacaaccga ggcatgaatg
     2401 agtttatcag tccgatggag aagcttttca aagtcatcgc cccacctctg aatgcaggga
     2461 agactcttac agatgagcaa gttgttatgg gcaacaagct tctggtgtac atcagctgtt
     2521 gcctggcagg tcgtgcctac cctctcggtg acattcctga agatcttgtt cccttggtta
     2581 aaaaccaggt ttttgagttt ctgattcgcc tgcattctgt agaagcatcc tccgaggaag
     2641 aagtctatcc ttatgttcgg actttgctac attttgacac aagagaattt ctgaatgtgc
     2701 tggcactgac ctttgaagac tttaaaaatg ataagcaagc tgtggaatac cagcagcgca
     2761 ttgtggatat tttattgaag gttatggtgg agaattcaga ttttaccccg tcacaagtgg
     2821 ggtgtctctt tacgttcctc gctcgtcagc tcgcaaagcc tgacaatacc ttgtttgtga
     2881 acaggaccct ctttgatcaa gtcctcgagt tcctctgtag ccccgacgat gactcccgcc
     2941 actctgaaag acagcaggtc cttttagaat tgctgcaggc cggaggcata gttcaatttg
     3001 aagagagtcg gctcatccgc atggcagaaa aggcagaatt ctatcaaatc tgtgaattta
     3061 tgtatgagcg ggaacaccag tatgacaaga tcattgactg ctacctgcac gacccattga
     3121 gagaggaaga agtcttcaat tatatccaca acatcttatc tattcctggt cacagtgctg
     3181 aggagaagca gtctgtgtgg cagaaagcaa tgaatcatat ggaggaactt gtgtccctga
     3241 agccctgcaa agccgcagag ctggtggcta ctcacttttc tgagcagatc gaagtggtca
     3301 ttggacagct tcagaaccag cttttgcttt tcaaattttt gaggagtctt cttgatccaa
     3361 gggaaggtgt tcatgtcaat caggagttgc tgcagatccc gcctcacatt acagagcagt
     3421 tcattgagct gctgtgccag ttcagtcctg accaagtcat acagacactg caggtccttg
     3481 agtgctaccg tctggaggaa acgattcaga ttacacaaaa gtatcaactc catgaagtca
     3541 ctgcgtatct gctggagaag aaaggggatg cacacggcgc cttcctgctg ctgctggaga
     3601 gactgcagag caggctgcaa gagatgacac ggcaggacga aaataccaag gaggacatcc
     3661 tgctgaaagg tgttgaagat accatggtag agacaattgc tctttgccag agaaattcac
     3721 agaatttgaa tcagcagcaa cgagaggctc tatggtttcc actgttggag gcaatgatga
     3781 caccacagaa gctgtccagc tcggctgctg ctcctcatcc gcactgtgaa gctctgaagt
     3841 ctttgaccat gcaagtccta aacagcatgg cagcgttcat cgccctcccg tccatcctac
     3901 agagaatctt gcaggaccca atttatggaa aaggaaagct tggagaaatc cagggcctta
     3961 ttctggggat gctggacacc ttcaactatg agcaaacctt gctagaaaca acagccagcc
     4021 tcctgaacca agatctccat tggtcactgt gtaacctgag agcatcagta tccagaggac
     4081 tcaatcccaa gcaggattac tgttctatat gtttacagca gtacaaaaga cgccaagaaa
     4141 tggctgatga aattattgtc tttagctgtg gccatttgta tcattcattc tgtctccaaa
     4201 gtaaggaatg caccctagag gttgagggtc agacgagatg ggcgtgtcac aaatgcagct
     4261 caagtaataa agcgggcaaa ctcagtgaaa atccttctga aaacaagaaa ggacggataa
     4321 cctcgtctca ggtaaaaatg tcgccctcgt atcatcagtc caaaggggat cctcccgcca
     4381 ggaaggcaaa ctcagaacct gttctggacc cacagcaaat gcaagccttt gatcagctct
     4441 gccgtctcta cagaggaagt tctaggttgg ctctccttac ggagctctcc cagaaccgag
     4501 gtggcgacag ctgcaggccg tttgctggcc cccagagtgg gcctgctttc aacagcgtct
     4561 tccagaagga gaacttccag ctgcagctcg cgcctccgcc tgtggctgaa gactgaggcc
     4621 tccctggaag cccaagctgc aggaggcagg aaggaccctc tgcgcaggct cagcctctgc
     4681 ctcccacact cctgcacaga ggcccaaggc agccctggag ccgccctgca accctcccct
     4741 ctcagtgcac tctccctgtt acaggtcaga ccgcagatgg gccggtttca tttcgctcag
     4801 aatattacct agttctaccc agccctttag gaaatggtgt ttacccagcc acattcgatg
     4861 tagcaagggg cgtggggagc ccatcgactg tgaagagcaa aggtcggcct gggaagagca
     4921 gcagccccgg aagcaggcat gtctgctggt gtttatgtta aaacccaggg aaatgggagc
     4981 ccaacctttg aaacaataaa tgtctcatgt ttgagtcctg caggcct
//
