LOCUS       NM_009336               1436 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus vacuolar protein sorting 72 (Vps72), mRNA.
ACCESSION   NM_009336
VERSION     NM_009336.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1436)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1436)
  AUTHORS   Xu,M., Yao,J., Shi,Y., Yi,H., Zhao,W., Lin,X. and Yang,Z.
  TITLE     The SRCAP chromatin remodeling complex promotes oxidative
            metabolism during prenatal heart development
  JOURNAL   Development 148 (8) (2021)
   PUBMED   33913477
REFERENCE   3  (bases 1 to 1436)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1436)
  AUTHORS   Zhao,B., Chen,Y., Jiang,N., Yang,L., Sun,S., Zhang,Y., Wen,Z.,
            Ray,L., Liu,H., Hou,G. and Lin,X.
  TITLE     Znhit1 controls intestinal stem cell maintenance by regulating
            H2A.Z incorporation
  JOURNAL   Nat Commun 10 (1), 1071 (2019)
   PUBMED   30842416
  REMARK    GeneRIF: Znhit1 promotes the interaction between H2A.Z and YL1
            (H2A.Z chaperone) by controlling YL1 phosphorylation. These results
            demonstrate that Znhit1/H2A.Z is essential for Lgr5+ stem cell
            maintenance and intestinal homeostasis.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1436)
  AUTHORS   Jacquet,K., Fradet-Turcotte,A., Avvakumov,N., Lambert,J.P.,
            Roques,C., Pandita,R.K., Paquet,E., Herst,P., Gingras,A.C.,
            Pandita,T.K., Legube,G., Doyon,Y., Durocher,D. and Cote,J.
  TITLE     The TIP60 Complex Regulates Bivalent Chromatin Recognition by 53BP1
            through Direct H4K20me Binding and H2AK15 Acetylation
  JOURNAL   Mol Cell 62 (3), 409-421 (2016)
   PUBMED   27153538
REFERENCE   6  (bases 1 to 1436)
  AUTHORS   Ruhl,D.D., Jin,J., Cai,Y., Swanson,S., Florens,L., Washburn,M.P.,
            Conaway,R.C., Conaway,J.W. and Chrivia,J.C.
  TITLE     Purification of a human SRCAP complex that remodels chromatin by
            incorporating the histone variant H2A.Z into nucleosomes
  JOURNAL   Biochemistry 45 (17), 5671-5677 (2006)
   PUBMED   16634648
REFERENCE   7  (bases 1 to 1436)
  AUTHORS   Doyon,Y., Selleck,W., Lane,W.S., Tan,S. and Cote,J.
  TITLE     Structural and functional conservation of the NuA4 histone
            acetyltransferase complex from yeast to humans
  JOURNAL   Mol Cell Biol 24 (5), 1884-1896 (2004)
   PUBMED   14966270
REFERENCE   8  (bases 1 to 1436)
  AUTHORS   Buchner,D.A., Trudeau,M., George,A.L. Jr., Sprunger,L.K. and
            Meisler,M.H.
  TITLE     High-resolution mapping of the sodium channel modifier Scnm1 on
            mouse chromosome 3 and identification of a 1.3-kb recombination hot
            spot
  JOURNAL   Genomics 82 (4), 452-459 (2003)
   PUBMED   13679025
REFERENCE   9  (bases 1 to 1436)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   10 (bases 1 to 1436)
  AUTHORS   Horikawa,I., Tanaka,H., Yuasa,Y., Suzuki,M. and Oshimura,M.
  TITLE     Molecular cloning of a novel human cDNA on chromosome 1q21 and its
            mouse homolog encoding a nuclear protein with DNA-binding ability
  JOURNAL   Biochem Biophys Res Commun 208 (3), 999-1007 (1995)
   PUBMED   7702631
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY294768.1 and AK140284.1.
            
            On Dec 23, 2005 this sequence version replaced NM_009336.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK140284.1, BC043029.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2                 BY294768.1         22-23
            3-1436              AK140284.1         1-1434
FEATURES             Location/Qualifiers
     source          1..1436
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 40.74 cM"
     gene            1..1436
                     /gene="Vps72"
                     /gene_synonym="Tcfl1; YL-1"
                     /note="vacuolar protein sorting 72"
                     /db_xref="GeneID:21427"
                     /db_xref="MGI:MGI:1202305"
     exon            1..173
                     /gene="Vps72"
                     /gene_synonym="Tcfl1; YL-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             57..1163
                     /gene="Vps72"
                     /gene_synonym="Tcfl1; YL-1"
                     /note="protein YL-1; transcription factor-like 1"
                     /codon_start=1
                     /product="vacuolar protein sorting-associated protein 72
                     homolog"
                     /protein_id="NP_033362.2"
                     /db_xref="CCDS:CCDS38543.1"
                     /db_xref="GeneID:21427"
                     /db_xref="MGI:MGI:1202305"
                     /translation="MSLAGGRAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDD
                     EYQGDQSDTEDEVDSDFDIDEGDEPSSDGEAEEPRRKRRVVTKAYKEPLKSLRPRKVS
                     TPASSSQKAREEKTLLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKG
                     PHCERPLTQEELLREAKITEELNLRSLETYERLEADKKKQVHKKRKCPGPIITYHSVT
                     VPLVGEPGPKEENVDVEGLDPAPTASALAPHAGTGTGAAAATPPAHCSRTFITFSDDA
                     TFEEWFPQGRPPKVPVREVCPVTHRPALYRDPVTDIPYATARAFKIIREAYKKYITAH
                     GLPPTASALGPGPPPPEPLPGSGPRALRQKIVIK"
     exon            174..326
                     /gene="Vps72"
                     /gene_synonym="Tcfl1; YL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            327..441
                     /gene="Vps72"
                     /gene_synonym="Tcfl1; YL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            442..618
                     /gene="Vps72"
                     /gene_synonym="Tcfl1; YL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            619..763
                     /gene="Vps72"
                     /gene_synonym="Tcfl1; YL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            764..1436
                     /gene="Vps72"
                     /gene_synonym="Tcfl1; YL-1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1301..1306
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Vps72"
                     /gene_synonym="Tcfl1; YL-1"
                     /note="hexamer: AATAAA"
     polyA_site      1319
                     /gene="Vps72"
                     /gene_synonym="Tcfl1; YL-1"
                     /note="major polyA site"
ORIGIN      
        1 gagaaccccg agctgggcca ggggctgaag gcggcagcgc agtcgctgta ggcggtatga
       61 gtttggctgg gggccgggcc ccacggaaaa ccgctgggaa ccggctttct gggctcctgg
      121 aagcagagga ggaagatgag ttctaccaga caacttacgg gggtttcacc gaggaatctg
      181 gagatgatga gtatcaagga gaccagtctg atacggagga tgaggtagac tctgactttg
      241 acattgatga aggggatgaa ccatccagtg atggagaagc ggaagagcca aggaggaagc
      301 gcagagtcgt caccaaagcc tataaggagc ctctaaagag cttgaggcct cgcaaggtca
      361 gcaccccagc aagcagctcc cagaaggcca gagaggagaa gacgctgctg ccactggagc
      421 tccaggacga tggctctgac agccgcaagt ctatgcgtca gtctacagct gagcacacac
      481 gacaaacgtt ccttcgggtt caagagaggc aaggacagtc ccggaggcgg aagggtcccc
      541 actgtgagcg accactaacc caggaagagc tgctcaggga ggccaagatc actgaagagc
      601 tcaacttacg ttcactcgag acctatgaaa ggctggaggc tgacaaaaag aagcaggttc
      661 acaagaagcg gaagtgccct gggccaataa tcacctacca ctcagtgacg gtgccgcttg
      721 ttggggagcc cggccccaag gaggaaaatg tggacgtgga aggccttgat cctgctccta
      781 cagcctctgc actggctcca catgctggga ccgggactgg agctgccgct gccacccctc
      841 ctgctcactg ctctcgcacc ttcatcacgt tcagtgatga tgcaacgttt gaagagtggt
      901 tcccccaggg gcgacccccg aaggtcccgg tgcgggaggt ctgcccagtg acccaccgtc
      961 cagctttgta ccgggaccct gttacagaca taccctatgc cactgctaga gccttcaaga
     1021 tcatccgtga ggcgtacaag aagtacatca ctgcccacgg acttccaccc accgcctcgg
     1081 cgctgggccc cgggccccca ccccccgagc cactacctgg ctctgggcct cgagccttgc
     1141 gtcagaagat tgtcatcaaa tagagacacc tgacccctag acagtccctc tcctgacctg
     1201 gctctccact ccgccctccc ttctgccaac cttcgccctt gtttccctca gttcctccct
     1261 agttcatttc atttacttgt gctcttcatt tttttaatct aataaaatgg taaaatcctt
     1321 tttgtctgat gtgtaaggtt ggggcagagg cagggggatt tctgagttcg aggccaacct
     1381 ggtctacaga gtgagttcca ggacagccag ggctaaacag acaaatcctg tcttgg
//
