LOCUS       NM_178851               4366 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus VPS39 HOPS complex subunit (Vps39), transcript variant
            2, mRNA.
ACCESSION   NM_178851
VERSION     NM_178851.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4366)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4366)
  AUTHORS   Bai,S., Wu,Q., Zhu,S., Zhang,Y., Chen,X., Su,M., Pan,J., Li,S.,
            Yue,T., Xu,L., Xie,D., Tian,C., Zhao,D., Li,X., Hou,J., Wang,L.,
            Fu,S., Xue,Y., Jiang,A., Li,D., Xu,T., Tian,Z., Zhou,R., Zhang,H.
            and Bai,L.
  TITLE     Vam6 reduces iNKT cell function in tumor via modulating AMPK/mTOR
            pathways
  JOURNAL   Front Immunol 13, 1051045 (2023)
   PUBMED   36741382
  REMARK    GeneRIF: Vam6 reduces iNKT cell function in tumor via modulating
            AMPK/mTOR pathways.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4366)
  AUTHORS   Jackson,J., Wischhof,L., Scifo,E., Pellizzer,A., Wang,Y.,
            Piazzesi,A., Gentile,D., Siddig,S., Stork,M., Hopkins,C.E.,
            Handler,K., Weis,J., Roos,A., Schultze,J.L., Nicotera,P.,
            Ehninger,D. and Bano,D.
  TITLE     SGPL1 stimulates VPS39 recruitment to the mitochondria in MICU1
            deficient cells
  JOURNAL   Mol Metab 61, 101503 (2022)
   PUBMED   35452878
  REMARK    GeneRIF: SGPL1 stimulates VPS39 recruitment to the mitochondria in
            MICU1 deficient cells.
REFERENCE   4  (bases 1 to 4366)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4366)
  AUTHORS   Davegardh,C., Sall,J., Benrick,A., Broholm,C., Volkov,P.,
            Perfilyev,A., Henriksen,T.I., Wu,Y., Hjort,L., Brons,C.,
            Hansson,O., Pedersen,M., Wurthner,J.U., Pfeffer,K., Nilsson,E.,
            Vaag,A., Stener-Victorin,E., Pircs,K., Scheele,C. and Ling,C.
  TITLE     VPS39-deficiency observed in type 2 diabetes impairs muscle stem
            cell differentiation via altered autophagy and epigenetics
  JOURNAL   Nat Commun 12 (1), 2431 (2021)
   PUBMED   33893273
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4366)
  AUTHORS   Brahmaraju,M., Shoeb,M., Laloraya,M. and Kumar,P.G.
  TITLE     Spatio-temporal organization of Vam6P and SNAP on mouse spermatozoa
            and their involvement in sperm-zona pellucida interactions
  JOURNAL   Biochem Biophys Res Commun 318 (1), 148-155 (2004)
   PUBMED   15110766
  REMARK    GeneRIF: Antibodies to VAMP and SNAP inhibited sperm-zona pellucida
            interaction, suggesting their possible involvement in sperm
            membrane vesiculation.
REFERENCE   7  (bases 1 to 4366)
  AUTHORS   Richardson,S.C., Winistorfer,S.C., Poupon,V., Luzio,J.P. and
            Piper,R.C.
  TITLE     Mammalian late vacuole protein sorting orthologues participate in
            early endosomal fusion and interact with the cytoskeleton
  JOURNAL   Mol Biol Cell 15 (3), 1197-1210 (2004)
   PUBMED   14668490
REFERENCE   8  (bases 1 to 4366)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   9  (bases 1 to 4366)
  AUTHORS   Falcon-Perez,J.M. and Dell'Angelica,E.C.
  TITLE     The pallidin (Pldn) gene and the role of SNARE proteins in
            melanosome biogenesis
  JOURNAL   Pigment Cell Res 15 (2), 82-86 (2002)
   PUBMED   11936273
  REMARK    Review article
REFERENCE   10 (bases 1 to 4366)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK140041.1, BY125125.1, AK038824.1, AB028844.1, BM249306.2 and
            AW060607.1.
            
            On Jan 26, 2018 this sequence version replaced NM_178851.3.
            
            Transcript Variant: This variant (2) lacks an alternate in-frame
            exon compared to variant 1. The resulting isoform (2) has the same
            N- and C-termini but is shorter compared to isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK159889.1, AK160109.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4                 AK140041.1         2-5
            5-336               BY125125.1         2-333
            337-4003            AK038824.1         322-3988
            4004-4213           AB028844.1         3980-4189
            4214-4349           BM249306.2         1-136               c
            4350-4366           AW060607.1         1-17                c
FEATURES             Location/Qualifiers
     source          1..4366
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 60.31 cM"
     gene            1..4366
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /note="VPS39 HOPS complex subunit"
                     /db_xref="GeneID:269338"
                     /db_xref="MGI:MGI:2443189"
     exon            1..223
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /inference="alignment:Splign:2.1.0"
     CDS             151..2778
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /note="isoform 2 is encoded by transcript variant 2;
                     vam6/Vps39-like protein; vacuolar protein sorting 39"
                     /codon_start=1
                     /product="vam6/Vps39-like protein isoform 2"
                     /protein_id="NP_849182.1"
                     /db_xref="CCDS:CCDS16619.1"
                     /db_xref="GeneID:269338"
                     /db_xref="MGI:MGI:2443189"
                     /translation="MHDAFEPVPILEKLPLQIDCLAAWEEWLLVGTKQGHLLLYRIRK
                     DVGCNRFEVTLEKSNKNFSKKIQQIHVVSQFKILVSLLENNIYVHDLLTFQQITTVSK
                     AKGASLFTCDLQHTETGEEVLRMCVAVRKKLQLYFWKDREFHELQGDFSVPDVPKSMA
                     WCENSICVGFKRDYYLIRVDGKGSIKELFPTGKQLEPLVAPLADGKVAVGQDDLTVVL
                     NEEGICTQKCALNWTDIPVAMEHQPPYIVAVLPRYVEIRTLEPRLLVQSIELQRPRFI
                     TSGGSNIIYVASNHFVWRLIPVPMATQIQQLLQDKQFELALQLAEMKDDSDSEKQQQI
                     HHIKNLYAFNLFCQKRFDESMQVFAKLGTDPTHVMGLYPDLLPTDYRKQLQYPNPLPT
                     LSGAELEKAHLALIDYLTQKRSQLVKKLNDSDHQSSTSPLMEGTPTIKSKKKLLQIID
                     TTLLKCYLHTNVALVAPLLRLENNHCHIEESEHVLKKAHKYSELIILYEKKGLHEKAL
                     QVLVDQSKKANSPLKGHERTVQYLQHLGTENLHLIFSYSVWVLRDFPEDGLKIFTEDL
                     PEVESLPRDRVLNFLIENFKALAIPYLEHIIHVWEETGSQFHNCLIQLYCEKVQSLMK
                     DYLLSLPTGKSPVPAGEEGGELGEYRQKLLMFLEISSHYDPGRLICDFPFDGLLEERA
                     LLLGRMGKHEQALFIYVHVLKDTKMAKEYCHKHYDQNKEGNKDVYLSLLRMYLSPPSI
                     HCLGPIKLELLEPQANLQAALQVLELHYSKLDTTKAINLLPANTQINDIRIFLEKVLE
                     ENAQKKRFNQVLKNLLHAEFLRVQEERILHQQVKCIITEEKVCMVCKKKIGNSAFARY
                     PNGVVVHYFCSKEVNSADT"
     exon            224..289
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /inference="alignment:Splign:2.1.0"
     exon            290..354
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /inference="alignment:Splign:2.1.0"
     exon            355..397
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /inference="alignment:Splign:2.1.0"
     exon            398..492
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /inference="alignment:Splign:2.1.0"
     exon            493..591
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /inference="alignment:Splign:2.1.0"
     exon            592..684
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /inference="alignment:Splign:2.1.0"
     exon            685..868
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /inference="alignment:Splign:2.1.0"
     exon            869..989
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /inference="alignment:Splign:2.1.0"
     exon            990..1110
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /inference="alignment:Splign:2.1.0"
     exon            1111..1240
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /inference="alignment:Splign:2.1.0"
     exon            1241..1383
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /inference="alignment:Splign:2.1.0"
     exon            1384..1527
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /inference="alignment:Splign:2.1.0"
     exon            1528..1669
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /inference="alignment:Splign:2.1.0"
     exon            1670..1756
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /inference="alignment:Splign:2.1.0"
     exon            1757..1830
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /inference="alignment:Splign:2.1.0"
     exon            1831..1929
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /inference="alignment:Splign:2.1.0"
     exon            1930..2047
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /inference="alignment:Splign:2.1.0"
     exon            2048..2176
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /inference="alignment:Splign:2.1.0"
     exon            2177..2279
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /inference="alignment:Splign:2.1.0"
     exon            2280..2325
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /inference="alignment:Splign:2.1.0"
     exon            2326..2475
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /inference="alignment:Splign:2.1.0"
     exon            2476..2610
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /inference="alignment:Splign:2.1.0"
     exon            2611..2702
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /inference="alignment:Splign:2.1.0"
     exon            2703..4351
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4191..4196
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /note="hexamer: AATAAA"
     polyA_site      4214
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /note="major polyA site"
     regulatory      4329..4334
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /note="hexamer: AATAAA"
     polyA_site      4351
                     /gene="Vps39"
                     /gene_synonym="A230065P22Rik; mVam6; Vam6; Vam6P"
                     /note="major polyA site"
ORIGIN      
        1 aggcaacagg aagtccggcg gcgaggatgg agttgttgct gaaggccctg tagcaggggt
       61 ccctggtgga atacgagtct tccctgtttt cggacggcag gctcctccca gcagcagggg
      121 cgggacagtg gcggtgaagc tcccgcagcc atgcatgacg ctttcgagcc ggtgccgatc
      181 ctggaaaagc ttcccctgca gatcgactgc ctggctgcct gggaggaatg gcttcttgtt
      241 ggaaccaagc aagggcatct tcttctctac aggattcgga aggatgttgg ttgtaacagg
      301 tttgaggtaa cactagagaa gtccaataag aacttttcca aaaagatcca gcagatccat
      361 gtggtttccc agtttaagat tctggtcagc ttgttagaaa acaacattta tgtccatgac
      421 ttactgacat ttcaacaaat cactacagtc tcaaaggcca agggcgcatc actgttcacc
      481 tgtgacctcc agcacactga gacgggtgag gaggtgttgc ggatgtgtgt ggcagtgagg
      541 aagaagctgc agctgtactt ctggaaggac agagaattcc acgaactgca gggagacttt
      601 agtgtgccag atgtgcccaa gtccatggca tggtgtgaaa attctatctg cgttggtttc
      661 aagagagact attacctgat cagggtggat ggaaaggggt ccatcaaaga gctcttccca
      721 acaggaaagc agctggagcc cttagttgcc cctctggcag atggaaaagt ggctgtgggt
      781 caggatgatc tgactgtggt gcttaacgag gaaggcatct gcactcagaa atgcgccctg
      841 aactggacag acatcccagt ggccatggag caccagcctc catacattgt tgcagtgttg
      901 ccacgatacg tggagatccg aacactggaa ccaaggcttc tggtccaaag cattgagttg
      961 caaaggcctc gcttcattac atcaggggga tcaaacatta tctatgtggc cagcaatcat
     1021 tttgtttgga gactcattcc tgtccccatg gcaacccaaa tccaacagct tctccaggac
     1081 aagcagtttg aattggctct gcagctcgcg gagatgaaag atgactcaga cagtgaaaag
     1141 cagcagcaga tccatcacat taagaacttg tatgccttca acctcttctg ccagaagcgc
     1201 tttgatgagt ccatgcaggt ctttgctaaa cttggcacag atcccaccca tgtgatgggc
     1261 ttgtaccccg acctactgcc cacggactac aggaagcaac tgcagtaccc caacccgctg
     1321 cccacactct ctggtgctga actggagaag gctcacttag ctctcattga ctacctgaca
     1381 cagaaacgga gccagttggt aaagaagctg aatgactcgg atcaccagtc cagcacctcc
     1441 ccgctcatgg agggcactcc caccatcaag tccaagaaga agttacttca gatcattgac
     1501 accactctgc tcaagtgcta cctccataca aatgtggccc tggtggctcc cttgctgcgc
     1561 ctggagaaca accactgtca tatcgaggag agtgagcatg tgctgaagaa ggctcacaag
     1621 tacagcgagc tgatcatcct gtatgagaag aaggggctcc atgagaaagc tctgcaggtg
     1681 ctagtggacc agtccaagaa agcaaactca cctttgaaag gccacgagag gacggtgcag
     1741 tatctgcagc atttaggcac agaaaacctt catctgattt tttcctactc agtctgggtg
     1801 ctgagagact tcccagaaga tggcctgaag atattcactg aagacctccc ggaggtagag
     1861 tctctgccac gagatcgagt actcaacttc ttgatagaga atttcaaggc tctagccatt
     1921 ccttatctgg aacacatcat ccacgtgtgg gaggagacag gctcacagtt ccacaattgc
     1981 ctgatccagc tgtactgtga gaaagtgcag agtctgatga aagactacct tctgtcgctg
     2041 cccacaggta aaagtccagt ccctgctgga gaggaaggag gtgaactggg agaataccga
     2101 cagaagctgc tcatgttctt ggagatttcc agccactatg atccaggccg gctcatctgt
     2161 gattttccct ttgatggcct cttagaagag cgagctctcc tgttggggcg catggggaag
     2221 cacgaacaag ctctcttcat ctatgtccac gtcttgaagg acacaaagat ggctaaggag
     2281 tactgccaca aacactacga ccaaaacaaa gaaggcaaca aagatgtgta tctgtccctg
     2341 cttcggatgt acctgtcacc tccaagcatt cactgcctgg ggccaatcaa actggagctc
     2401 ctggagccac aggccaacct ccaggctgcc ctgcaagtcc tagagctgca ctacagcaaa
     2461 ttagacacca ccaaggcaat caaccttctg ccagcaaaca ctcagatcaa tgacatacgc
     2521 atctttctag aaaaggtctt agaagaaaat gcacaaaaga aacggttcaa tcaagtgctt
     2581 aagaatcttc tccatgcgga gttcctcagg gttcaggaag agcgaatttt acaccagcag
     2641 gtgaagtgca tcatcactga ggagaaggtg tgcatggtat gcaagaagaa gattgggaac
     2701 agtgcatttg caagataccc caatggggtg gttgtgcact acttctgctc caaagaggta
     2761 aactcagccg acacctgagc ccggcagccc aagcactcag cagtggacag ctcagctttc
     2821 ccagagagtt gaaggagcag ccaccttgag aaccgtgcac tgctaccagg gacgatgctg
     2881 gccaccttgc tctctggaac atctccgaat taactggact tgtgacctgg cattgccggc
     2941 tttttactag aagagattag ttatatctta cgctgttatg ttgcagacaa ttccaggagt
     3001 ttaacccctg cttggacagg aggaaatgca ccatcttgcc tttgtatacc aatcatctgg
     3061 acaaggagat ttcatctcaa gtgtttgtac ccatggggtt gttgactgtg agttttctat
     3121 tacaataact acacagcttc acaagattcc cccagcatgg cggcctggag agtcccatgg
     3181 gagcccagca ctagagcttg ccagcccact gaccgcaggc tgtttatact gccagtgttt
     3241 tctccaggag tctccctgct tatcccttcc gttttcagtc gccttttctt cctcactatt
     3301 tattttaccc ctggatctct tcccttgtac cgtccacgct tcccctccca ctgtgtagag
     3361 tgggaggtag agtaactaat gcttaaatgt ggcaaatggg aggccctgat gagcaggtgt
     3421 catggacatt gtatgaaggg tctcaggagc tgaacttttc tactaagatg tgtaggagaa
     3481 cacaagtctc tgtaggtgta ggctttggta cctccccggg gcagcactgt gcagggtgtg
     3541 tggtctaggc aggatctctc tagaagtgcc tgcctcggcc actcaccagc tgcttggaca
     3601 ggctgttgat tggacaggct gttgagtctt tataggtgag cgctgagcat cttcctccac
     3661 tctagccact ttctgtcctg ttgttttcct ggccatagtt gttccttggc ctttcttctg
     3721 caagactgga ggatcgagct aggatagctt ggtaaagtat gtctcactgc acacagggaa
     3781 cagctgacca gaaaccaata gtgatgagat ggcgtgcagg tttgtggggc actgaggaat
     3841 ggcaaagagt aatgcaggag cagctctgtt gagtatgtca gggagccggc aagaggtacg
     3901 cagagcaaga ggtacacagc aacttctggc cttggaggct acagacacca ggcacacaca
     3961 tgcacataca tatatgcagg ccacacaccc atacataaag tttaaaaaaa aacagtgctg
     4021 cccatgaacc catctgcacc accttaaaat gtacttcctc gggagtggca ctgggatgcc
     4081 aggccactcc ccataggaca ggaccagaac ttgtgccatc atgtgagtcc tgccctttta
     4141 cctggtaggc ttgtagcatc ccttcttatg aactgtgttt gaagcagtag aataaagcct
     4201 gtattttctc ctgggtggtg tgcatactta attctgtttc cctaaactcc atcctttctt
     4261 cccaggatcc tgcccttcat agagggaaca gggtagctcc agcctaagga tgatggaggc
     4321 tgcttctcaa taaacataag tgaaaaacca aaaaaaaaaa aaaaaa
//
