LOCUS       NM_177876               2512 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus vacuolar protein sorting 37B (Vps37b), mRNA.
ACCESSION   NM_177876
VERSION     NM_177876.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2512)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2512)
  AUTHORS   Jerome-Majewska,L.A., Achkar,T., Luo,L., Lupu,F. and Lacy,E.
  TITLE     The trafficking protein Tmed2/p24beta(1) is required for
            morphogenesis of the mouse embryo and placenta
  JOURNAL   Dev Biol 341 (1), 154-166 (2010)
   PUBMED   20178780
REFERENCE   3  (bases 1 to 2512)
  AUTHORS   Taniwaki,T., Haruna,K., Nakamura,H., Sekimoto,T., Oike,Y.,
            Imaizumi,T., Saito,F., Muta,M., Soejima,Y., Utoh,A., Nakagata,N.,
            Araki,M., Yamamura,K. and Araki,K.
  TITLE     Characterization of an exchangeable gene trap using pU-17 carrying
            a stop codon-beta geo cassette
  JOURNAL   Dev Growth Differ 47 (3), 163-172 (2005)
   PUBMED   15840001
REFERENCE   4  (bases 1 to 2512)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   5  (bases 1 to 2512)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC122753.11.
            
            On May 2, 2007 this sequence version replaced NM_177876.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC026744.1, AK149893.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-159               AC122753.11        180011-180169       c
            160-331             AC122753.11        158597-158768       c
            332-414             AC122753.11        155518-155600       c
            415-2512            AC122753.11        152550-154647       c
FEATURES             Location/Qualifiers
     source          1..2512
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 63.32 cM"
     gene            1..2512
                     /gene="Vps37b"
                     /gene_synonym="2300007F24Rik"
                     /note="vacuolar protein sorting 37B"
                     /db_xref="GeneID:330192"
                     /db_xref="MGI:MGI:1916724"
     exon            1..159
                     /gene="Vps37b"
                     /gene_synonym="2300007F24Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             49..906
                     /gene="Vps37b"
                     /gene_synonym="2300007F24Rik"
                     /note="ESCRT-I complex subunit VPS37B"
                     /codon_start=1
                     /product="vacuolar protein sorting-associated protein 37B"
                     /protein_id="NP_808544.1"
                     /db_xref="CCDS:CCDS19670.1"
                     /db_xref="GeneID:330192"
                     /db_xref="MGI:MGI:1916724"
                     /translation="MAGAVSEARFAGLSLMQLHELLEDDAQLGDMVRGMEEAQTVQLN
                     KEMTLASNRSLAEGNLLYQPQLDAQKARLTQKYQELQVLFEAYQIKKTKLDKQSNNAS
                     LETLLALLQAEGAKIEEDTENMAEKFLDGELPLDSFIDVYQSKRKLAHMRRVKVEKLQ
                     ELVLKGQRHPQAGAPPPPRVPEPSPATALPYPSLEATGLPSVVPRRIPPPPPPVPAGH
                     VATPFAAAMGSGQVSAYPGLQCPPLPPRVGLPSQQGFSAQLVSPYPPALPQRPPPRMA
                     PHQPGFILQ"
     exon            160..331
                     /gene="Vps37b"
                     /gene_synonym="2300007F24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            332..414
                     /gene="Vps37b"
                     /gene_synonym="2300007F24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            415..2512
                     /gene="Vps37b"
                     /gene_synonym="2300007F24Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2488..2493
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Vps37b"
                     /gene_synonym="2300007F24Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2512
                     /gene="Vps37b"
                     /gene_synonym="2300007F24Rik"
                     /note="major polyA site"
ORIGIN      
        1 gcttggcggc ccgagtggcg gcggcggcgg cagcgtccga gtggcgggat ggcgggcgcc
       61 gtgagcgagg cgcgcttcgc ggggctgtcg ctgatgcagc tgcacgagct gctggaggac
      121 gatgcacagc tcggcgacat ggtgcggggt atggaagagg cgcagacggt tcagcttaac
      181 aaagagatga ccctggctag caaccggagc ctggcagagg gaaaccttct gtaccagccc
      241 caactggatg ctcagaaagc tcgcctgacc caaaaatacc aggaactcca ggttctcttt
      301 gaggcctatc agataaagaa gaccaaacta gataaacagt ctaacaacgc ttccttggag
      361 actctgttag cgcttcttca agcggaaggg gcaaagattg aggaggacac tgagaacatg
      421 gcagagaagt ttctggatgg agagcttcct ctagattcct ttattgatgt ctaccagagc
      481 aagcggaagc tggcgcacat gcgccgtgtg aaagtggaga agctccagga gctggtgctg
      541 aagggacaga gacacccgca ggccggggcc ccgccaccac ccagggtgcc tgagccctca
      601 cctgccaccg cccttcccta cccctctctg gaggccactg ggctcccttc tgtcgtgcct
      661 cggcgtattc ccccccctcc acccccggtg cctgcaggac acgtagccac ccctttcgct
      721 gctgccatgg gctcgggaca ggtttctgca tacccgggat tacagtgccc acccctgcct
      781 cccagagtgg gcctcccctc tcagcaagga ttctccgcac agttggtgtc accgtaccca
      841 ccagccctgc cccagagacc ccctccacgg atggccccac accagccagg cttcatcctg
      901 cagtgagctc gggtgcctgc tcttcctgca agacatcctc tgcctgccgt gccgagctct
      961 gcaaacagag gctgtgcggt tcagcatctg ggccaagggc ttgggtgccc tgggtcagcg
     1021 tgcccacctg attttagaac tgtaggtccg tggtaagtaa gagagcaggt tctgtgcacc
     1081 aagggagcgc tgtttgtgcc aggccagtct gcatcacctc aatctgtgtt gggtgtgatt
     1141 tctgagtgtc tcgggctgat ggacttgtgc atttggaaag attaccccca cccccaggtt
     1201 agaatcctgg ctctcctgtt gcagctttat ttaataagca tgattaatta tatgttttat
     1261 tttcgagtct tggcccacca gctgccgtgg cgctagtaaa gactggtctc agctggccag
     1321 cctggaatgt gtgcccacgg ccaggccctg ctgggcagct gtgctgttca ccgagtgtgc
     1381 agggcaggcc agcccagtaa cctcccactc ctgccatgct gggtgctctc atggttcaaa
     1441 gccacaggca gagtttgcac ttggctgctg tgaggtgtgc agaggccagg cgaactgtgg
     1501 cccggggtgc gaggccagtg tgagccctca gccctcccca cacacctcaa gccgcgtcac
     1561 ggtttctgtg aagaagaaaa aaagatactc aatgttttta ctacacttgt aattttcctg
     1621 ttttatattt caaaagaaaa cttttttgac actctcaaga ccattcaggg aaactttttt
     1681 taaaatgcag atactgtttt gagctggttt aaaaaatgca gatttattga gtgccgcttc
     1741 ctgtcgggca agcagtgcac ggtcacatct gccagtgccc gtgctgtgcc ttagcttcac
     1801 tggtgccagg actcggagcc cgcggcgtgc cagccgcagc tgccctatgg agccgaagac
     1861 cagctaggta gggcctggcg ggcctcgtca ctttgtgatg ggtcaggagt ggtccatctt
     1921 cctccacccc ggataatctc aggagcaatg ctgcaggtgc tggcgtaggc atgggagggg
     1981 tttggggaca gcccgcccca cagggttggc agtggccgct ccctcctctc tgggatgtca
     2041 tctgcaggtg ccacatgtgc agagttccca gggcccggct ggggaggggc agccccacac
     2101 ctgttcccag aagagggctg cgagcctgtt ggtagaactt agaaccccac cttcaccctg
     2161 ccagctggct acagcccaag gtaacacagt caaggcagcg ctgattagtg agcctgcccc
     2221 agctgggcca ccggcagggc catcagcctt tgtccccaag ttggactgtt ttcctctcca
     2281 tggatttgga ctctgtaccc tactggaacc actctgtaaa gagacaaagc tgtatgtgcc
     2341 acttcagtac ctctgccacc aggaacgccc actgccagtc tcgggccgca gccacatggg
     2401 agctccgggt ggatgcagta aaggggccgc caggctgacc ttgccaggcc atagctggca
     2461 ctggggctgt aaagctgtag aactcttaat aaattgagaa ttattaattt ca
//
