LOCUS       NM_033560               6379 bp    mRNA    linear   ROD 28-JAN-2025
DEFINITION  Mus musculus vacuolar protein sorting 37A (Vps37a), mRNA.
ACCESSION   NM_033560
VERSION     NM_033560.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6379)
  AUTHORS   Hamamoto,K., Liang,X., Ito,A., Lanza,M., Bui,V., Zhang,J.,
            Opozda,D.M., Hattori,T., Chen,L., Haddock,D., Imamura,F., Wang,H.G.
            and Takahashi,Y.
  TITLE     Unveiling the physiological impact of ESCRT-dependent autophagosome
            closure by targeting the VPS37A ubiquitin E2 variant-like domain
  JOURNAL   Cell Rep 43 (12), 115016 (2024)
   PUBMED   39607828
REFERENCE   2  (bases 1 to 6379)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 6379)
  AUTHORS   Hermosilla Aguayo,V., Martin,P., Tian,N., Zheng,J., Aho,R., Losa,M.
            and Selleri,L.
  TITLE     ESCRT-dependent control of craniofacial morphogenesis with
            concomitant perturbation of NOTCH signaling
  JOURNAL   Dev Biol 503, 25-42 (2023)
   PUBMED   37573008
REFERENCE   4  (bases 1 to 6379)
  AUTHORS   Xue,W., Kitzing,T., Roessler,S., Zuber,J., Krasnitz,A., Schultz,N.,
            Revill,K., Weissmueller,S., Rappaport,A.R., Simon,J., Zhang,J.,
            Luo,W., Hicks,J., Zender,L., Wang,X.W., Powers,S., Wigler,M. and
            Lowe,S.W.
  TITLE     A cluster of cooperating tumor-suppressor gene candidates in
            chromosomal deletions
  JOURNAL   Proc Natl Acad Sci U S A 109 (21), 8212-8217 (2012)
   PUBMED   22566646
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY085136.1, AK016385.1, AK137479.1, BY549007.1 and AC158915.4.
            
            On Aug 11, 2006 this sequence version replaced NM_033560.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC039290.1, SRR1660815.109628.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-20                BY085136.1         1-20
            21-84               AK016385.1         3-66
            85-1208             AK137479.1         70-1193
            1209-1738           AK016385.1         1192-1721
            1739-1795           BY549007.1         399-455
            1796-6379           AC158915.4         51295-55878
FEATURES             Location/Qualifiers
     source          1..6379
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 23.89 cM"
     gene            1..6379
                     /gene="Vps37a"
                     /gene_synonym="2210018P21Rik; 4930592A21Rik; D8Ertd531e"
                     /note="vacuolar protein sorting 37A"
                     /db_xref="GeneID:52348"
                     /db_xref="MGI:MGI:1261835"
     exon            1..451
                     /gene="Vps37a"
                     /gene_synonym="2210018P21Rik; 4930592A21Rik; D8Ertd531e"
                     /inference="alignment:Splign:2.1.0"
     exon            452..526
                     /gene="Vps37a"
                     /gene_synonym="2210018P21Rik; 4930592A21Rik; D8Ertd531e"
                     /inference="alignment:Splign:2.1.0"
     exon            527..641
                     /gene="Vps37a"
                     /gene_synonym="2210018P21Rik; 4930592A21Rik; D8Ertd531e"
                     /inference="alignment:Splign:2.1.0"
     exon            642..742
                     /gene="Vps37a"
                     /gene_synonym="2210018P21Rik; 4930592A21Rik; D8Ertd531e"
                     /inference="alignment:Splign:2.1.0"
     exon            743..968
                     /gene="Vps37a"
                     /gene_synonym="2210018P21Rik; 4930592A21Rik; D8Ertd531e"
                     /inference="alignment:Splign:2.1.0"
     exon            969..1039
                     /gene="Vps37a"
                     /gene_synonym="2210018P21Rik; 4930592A21Rik; D8Ertd531e"
                     /inference="alignment:Splign:2.1.0"
     exon            1040..1167
                     /gene="Vps37a"
                     /gene_synonym="2210018P21Rik; 4930592A21Rik; D8Ertd531e"
                     /inference="alignment:Splign:2.1.0"
     exon            1168..1226
                     /gene="Vps37a"
                     /gene_synonym="2210018P21Rik; 4930592A21Rik; D8Ertd531e"
                     /inference="alignment:Splign:2.1.0"
     exon            1227..1295
                     /gene="Vps37a"
                     /gene_synonym="2210018P21Rik; 4930592A21Rik; D8Ertd531e"
                     /inference="alignment:Splign:2.1.0"
     exon            1296..1439
                     /gene="Vps37a"
                     /gene_synonym="2210018P21Rik; 4930592A21Rik; D8Ertd531e"
                     /inference="alignment:Splign:2.1.0"
     exon            1440..1520
                     /gene="Vps37a"
                     /gene_synonym="2210018P21Rik; 4930592A21Rik; D8Ertd531e"
                     /inference="alignment:Splign:2.1.0"
     exon            1521..6379
                     /gene="Vps37a"
                     /gene_synonym="2210018P21Rik; 4930592A21Rik; D8Ertd531e"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1771..1776
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Vps37a"
                     /gene_synonym="2210018P21Rik; 4930592A21Rik; D8Ertd531e"
                     /note="hexamer: ATTAAA"
     polyA_site      1791
                     /gene="Vps37a"
                     /gene_synonym="2210018P21Rik; 4930592A21Rik; D8Ertd531e"
                     /note="major polyA site"
     regulatory      5985..5990
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Vps37a"
                     /gene_synonym="2210018P21Rik; 4930592A21Rik; D8Ertd531e"
                     /note="hexamer: AATAAA"
     polyA_site      6002
                     /gene="Vps37a"
                     /gene_synonym="2210018P21Rik; 4930592A21Rik; D8Ertd531e"
     regulatory      6325..6330
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Vps37a"
                     /gene_synonym="2210018P21Rik; 4930592A21Rik; D8Ertd531e"
                     /note="hexamer: AATAAA"
     regulatory      6334..6339
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Vps37a"
                     /gene_synonym="2210018P21Rik; 4930592A21Rik; D8Ertd531e"
                     /note="hexamer: ATTACA"
     polyA_site      6348
                     /gene="Vps37a"
                     /gene_synonym="2210018P21Rik; 4930592A21Rik; D8Ertd531e"
     polyA_site      6353
                     /gene="Vps37a"
                     /gene_synonym="2210018P21Rik; 4930592A21Rik; D8Ertd531e"
ORIGIN      
        1 aggaggcggg gcgggcaggt gacgaacgcc ccggcgttgg agcagctgag ccggcaaggc
       61 gaccaggcct agctaactga ccccggggtg gtggtggccc ggagcacacc ggggttccgt
      121 ccagccgacg agtcgccctt ctccagccgc ccgcagtggt agctcggacc cccggggcca
      181 gggactcacg agcgcggcgt gtgggagacg gcgcggcccc tgggcacccc gtccgggccg
      241 tgctcgatcg cccgggaagc actgggctaa gcgaggagca gcaggccaga accttgtagg
      301 gcctcgggcc cggggacccg aggaggatga gctggctctt tcccctggcg aagagcgcgt
      361 catcctccgc ggctgggtcc cctgccggcc tcaccagtct ccagcagcag aagcagcggc
      421 tgatcgagtc actccggaac tcccattcca gtatagctga aatacaaaaa gatgtggaat
      481 acagattgcc attcacagta aacaacctga caattaacat taatatatta cttcctccac
      541 agtttcctca ggaaaagcca gtgattagtg tttatccgcc aatcagacat catttaatgg
      601 atagtcaagg attatatgtt acctctccat tagtaagcaa ttttacaatg cactcagatc
      661 ttggaaaaat tattcaaagt cttttggatg agttctggaa gaatcctcca gttttagctc
      721 ctacttcaac aacatttcca tacctgtata gtaatccagg tgggatgcct ccgtacccct
      781 cccaggggtt tccatttctt cctccatatc ctccaccaga agctaacagg aatatcacat
      841 ccttgtctgt agctgacact gtttcttctt caaccacaag ttacactgca gctaagcccg
      901 tggcgccttc atttggcatc ctttcaagtc tgccattacc agttcccaca actgaatctt
      961 cagcatcggt taaccaaaat ggttttggtt ataagatgcc ggatattcct gatgcatttc
     1021 cagaactttc agaactaagt gtgtcacagc tcacagatat gaatgaacag gaggaggtat
     1081 tactagaaca gtttctgatg ttgcctcaac taaaacaaat tattactgac aaggaagact
     1141 tagtaaaaaa tatcgaggaa ttagcaagaa aaaatctcct tttggaacat agcttggaag
     1201 gcaaaaggca aaccgtttta gataagtatg aattacttct acaaatgaaa tctacctttg
     1261 aaaagaagat gcaaaggcaa catgaactca gtgagagttg tagtgcaagt gctctacagg
     1321 caagattgaa agtagctgca cacgaagctg aggaagaatc ggataatatt gctgaagact
     1381 tcttggaggg aaaaactgaa atagatgatt ttctcaatag cttcaaggaa aagagaacaa
     1441 tttgccactg tagaagagct aaagaagaga agcttcacca ggtgatagcg atgcacagcc
     1501 aatttcatgc tcctctctag attttcctga aaccatgaac taccaagaga gaaatgggac
     1561 acaggcctaa gcacattgtt ttctatttat gacttaggga tgggcacttg aaaccatggc
     1621 tgaggtccag atgcgatgta gattgtctat cacctgagac tgattccgta cagattagaa
     1681 tgactgctat atttgacaaa actttctgca ctatttgcac taaagatgtt tattgttgac
     1741 aaatcctgta tttaagttcc tctatttctg attaaacatc tatgcatgta attctagcta
     1801 atttttaata tttttaaaaa ctactgattt acatttttag ttttaacttg aagctgcctc
     1861 atttatcaag agtgcttatt acttagattc ttcttcctgt cagccttttc tttcaaaacc
     1921 tattttcagc tgtgaaaagg tcatctagcc caccccgata cacacacaca catacacaca
     1981 cagacacaca cacacacaca cacacacaca cacacacaca cacacacacc cctttctttc
     2041 tagatgatga aactgtccag agcagtttgt tttcagatat tcagtgtcag gaaacagcag
     2101 tcctgccaag gtgccatctc aagaaagcaa cctgtaatac ctgcagtaaa taagagtgaa
     2161 gaatctactt tcttacagtt tcactttcag actaaagata catttaggca gcgatacagg
     2221 tcaatgcatt ggttgtattt tgttctggaa caggttgcac tgtgtagccc actctagcct
     2281 caaacttgtg cttctcctcc ctgagtacag ggttacagac aggtgccatc atctcataaa
     2341 tagatatttt acttattttt aaaactgtct ttcacttaaa ccagtacaat acagacttcc
     2401 atgctaacta aaataaataa gtatatatgg gttttgggta aatgatactc cttttatatt
     2461 ccaaatgtaa aaacaaacaa ttccttttgt taagaaatgg taaatctagg cagaaatagt
     2521 aaaattttaa tactttgact tgacttttta aacatttttt ttcctaagaa agctttataa
     2581 taacaagtaa tgtcttaatt tttaatgaat ttaattttct aattgtagat gtattcagca
     2641 atttgtttct gtattttgtc acagagctaa agaagaaaat gagtacatat ctgaggttgg
     2701 taagttagga cctaaatcac taaataccat aacacataat tgctcagttt tcatccgtga
     2761 ctgtcattcc aaagcctgca tacattatgg attgtcttca tttttcttac tctacatatt
     2821 tttggtaatg gagttttaag aaagtcataa atattttctt attgaaaatt tttttcatgt
     2881 ttgtggaaga catattcctg tgactataaa gattatcccg tgctgggtat gcaccatgat
     2941 agctgcctgt cttgctggcg ctaatgttaa gggtatgcta tggaatcctc aggcagacct
     3001 acagatatag gtgagataac aggtggagtc atgtttcaca tttgtgacca acttgggggc
     3061 attcagagac ttctgagtgt actggtattt gtgtttaaca ttcccagcag tcaccatagt
     3121 cagtggagaa tttgccagtc acagtctagt tgctttctta aaaaaccagg gatatcccag
     3181 aacaagagac cagcagtctt cttattaagg tttctgctag acacctcact cagtattgta
     3241 gaaagactac ccagagacaa cacaagtgtg acacacaaac acaaacacac accacacttg
     3301 ctcacccagg ccagggcatg cttttcttta aatttgtatt atccaagttt cattgtcaat
     3361 taatgaagca taatttctcc ctaaaaattc agagagcctc tttacaatcc agacattaaa
     3421 ccaagacatt tgaccacagt tgcttgcctt tagcaagttg acaaactagt tcagacatgt
     3481 ttattacttg tagtgaatat ctgaatatgc cagtgtgaat ttgcattctt tatttgcagg
     3541 agacagagta catggttgta attttatggc catatttttt ctttgtaaaa attggctata
     3601 gatctgaata ccaaacacat actcggattt tactttagta taaaggaaag cttaggaatt
     3661 actagactac ctaggtagaa tttgtcaagg atatttaaag gtaagctgta acaagtcggg
     3721 aaagtcaaag ttgggtgaaa acttcagatt aaatgaacag agtatagaac aaaggttgtt
     3781 tgaccacagt ttatatattt aaattgcagg acagctaaga ttctgttgta ggagaaagaa
     3841 gtaaattgaa gttgtgcttt ctgttctttt aaggcagggt ttctagccca gactgcgctc
     3901 taactttgat gtaactgagg atgacctggc tgtcgggtct tccacctctt gagtactagg
     3961 agcctaagca tgtatcacca accccagtcc tgtggagctt ggggactgag ctcagggctt
     4021 catgcctgga aggaaggcac tcttatctat tggccgacct gcatcctctt aaggaatgaa
     4081 aacttgggct ggggaggtgg ctaagtgcta acttgtgtgt catgcaagca tgagggaccc
     4141 gattcaaatt cttaggacct atataaaaac ctggtacatg gtagaacagg cctgaaattc
     4201 catcactcct atacaggaga ggaatgagag acttgtccca ggaagctttg caggccaatt
     4261 tatatagtag gcagaatggc agccagtgag gcccttgtta caaacaaggt cggggcacgg
     4321 cctgacacct gttgttcagt gttcctctca cttcagcact gaaggttgct gggaggtttt
     4381 gttttgttta aattgccaaa tgacttgttc aaacatgatc aaaattacta atcaattgag
     4441 ctgtaactat taaaggttgg gaagtaatgt cctgaataag ttatatattt tgaagtattc
     4501 tctgaacact gcactaaata ataaaacacc tcacaactga agcttcattt agagtgaaca
     4561 tgtagtacta gaggtttcta gttgaatcga ccatgactta tccagggact ctgaaaggca
     4621 ggctgcagtg agcatgtgta gcttcagtat tgacttgtaa aaaaaataaa aatgactcca
     4681 tgaacatacc taaattatgt cttgtaaagg gatggaggga acaaaaagcg tgtggctctg
     4741 atgctaataa aggtgtcaca ttaaaaagta aaaaatttaa atacatacat actgcttgtt
     4801 tttccaaata tgtagtacag atgatgtttt atctttgttg ttgacctatt gtctaaagag
     4861 caggtactat acaaatggcg aaacagccag gcgtcatgac acacaccttc aatgccagca
     4921 cttaggtggc aaaagcaggc aggtccctga gtttgaggtc agccagggct acagagtcag
     4981 atgttgtctt aaaaaaagaa agaaagaaag aaaataagtg atttatgtta taaagctgta
     5041 aaagccattc ccactatatt ccatatgttt attagctatt ctataggaaa tgagtaaata
     5101 ttccttaggc ttacttggga aactttccaa cagaaaatgc tcaatttaac atctaaagga
     5161 attacacttg ctttattttt gtattaataa tatttttata ttacaggcct ttagtatatt
     5221 aaattcattc tgtcttcaaa tgtgagcatt attatattgt atgacattat gtgatgtgtg
     5281 tgtataactc acactatgtt ttaagtctct tatcctttca tattactgta tttctatttc
     5341 caaaaaaatt gaatacatta tctgataaaa attttcacac tttaaagtac tgttataaaa
     5401 aactaagatt aaatgtatct ctttattaga atgtacttac actgtaaaat catataataa
     5461 gaacatttca gtatgttcaa acacagcaac atttctccat taagagtttt cagatcaaaa
     5521 gctcaattca aatcctgttt taaatgcatt ttaacagaaa cttcagaatt gccatccagt
     5581 agtccatggt catgagatat tgctaatgtt acagaaaaca ttagctttct atagaatttg
     5641 taaaatgaaa agtgctgtaa cctttattcc ctgtgtttag cagatgggtt gggggtttga
     5701 agaatggctc ccaaaggctc atctatttga atgctctgtt cctggttggt ggaactgttt
     5761 aggagggatt aggagatgtg gccttgtggg agggggtttg ttcctgggag ctgcctttaa
     5821 attttcaaaa agcccatgcc ttttctagtt agctctcact gcctcttggt tatgtcttga
     5881 aatgtgagct gtcagctgct gctccaatgc catacctgct tggctgatac catgccttcc
     5941 accatgatgg ttgtagattc taaccctctg aaactgtaag tcctaataaa tcctttattc
     6001 tagttgcctt ggttgtggtg tcttatcaca gaaagcatgc gataactaca tgataagcaa
     6061 attccctcgt tcttgacctt ttcccttgtt gatgtatcac tacctactgc atttagagtg
     6121 ttgtagtttg caatcaggtt ggctggctca cagttttgtt atgtgtaatc tctgaaagag
     6181 tagtaaaagg ctactaagag ctaatgtctg gactcagatt cgagatggag aaaatgaatc
     6241 cagcttcagc ttaataggtt ctacattcat ggtaaagaaa gacagacatt tttttgagaa
     6301 gcagaagatg ctccacaggg gaaaaataaa atgattacat ttataacaga aaagggtact
     6361 ctccatattt atttctttt
//
