LOCUS       NP_031860                297 aa            linear   ROD 31-DEC-2024
DEFINITION  vacuolar protein sorting-associated protein 26C [Mus musculus].
ACCESSION   NP_031860
VERSION     NP_031860.1
DBSOURCE    REFSEQ: accession NM_007834.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 297)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (residues 1 to 297)
  AUTHORS   Vos,D.Y., Wijers,M., Smit,M., Huijkman,N., Kloosterhuis,N.J.,
            Wolters,J.C., Tissink,J.J., Pronk,A.C.M., Kooijman,S.,
            Rensen,P.C.N., Kuivenhoven,J.A. and van de Sluis,B.
  TITLE     Cargo-Specific Role for Retriever Subunit VPS26C in Hepatocyte
            Lipoprotein Receptor Recycling to Control Postprandial
            Triglyceride-Rich Lipoproteins
  JOURNAL   Arterioscler Thromb Vasc Biol 43 (1), e29-e45 (2023)
   PUBMED   36353989
REFERENCE   3  (residues 1 to 297)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   4  (residues 1 to 297)
  AUTHORS   Yaylaoglu,M.B., Titmus,A., Visel,A., Alvarez-Bolado,G., Thaller,C.
            and Eichele,G.
  TITLE     Comprehensive expression atlas of fibroblast growth factors and
            their receptors generated by a novel robotic in situ hybridization
            platform
  JOURNAL   Dev Dyn 234 (2), 371-386 (2005)
   PUBMED   16123981
REFERENCE   5  (residues 1 to 297)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   6  (residues 1 to 297)
  AUTHORS   Gitton,Y., Dahmane,N., Baik,S., Ruiz i Altaba,A., Neidhardt,L.,
            Scholze,M., Herrmann,B.G., Kahlem,P., Benkahla,A., Schrinner,S.,
            Yildirimman,R., Herwig,R., Lehrach,H. and Yaspo,M.L.
  CONSRTM   HSA21 expression map initiative
  TITLE     A gene expression map of human chromosome 21 orthologues in the
            mouse
  JOURNAL   Nature 420 (6915), 586-590 (2002)
   PUBMED   12466855
REFERENCE   7  (residues 1 to 297)
  AUTHORS   Reymond,A., Marigo,V., Yaylaoglu,M.B., Leoni,A., Ucla,C.,
            Scamuffa,N., Caccioppoli,C., Dermitzakis,E.T., Lyle,R., Banfi,S.,
            Eichele,G., Antonarakis,S.E. and Ballabio,A.
  TITLE     Human chromosome 21 gene expression atlas in the mouse
  JOURNAL   Nature 420 (6915), 582-586 (2002)
   PUBMED   12466854
REFERENCE   8  (residues 1 to 297)
  AUTHORS   Pletcher,M.T., Wiltshire,T., Cabin,D.E., Villanueva,M. and
            Reeves,R.H.
  TITLE     Use of comparative physical and sequence mapping to annotate mouse
            chromosome 16 and human chromosome 21
  JOURNAL   Genomics 74 (1), 45-54 (2001)
   PUBMED   11374901
REFERENCE   9  (residues 1 to 297)
  AUTHORS   Nakamura,A., Hattori,M. and Sakaki,Y.
  TITLE     Isolation of a novel human gene from the Down syndrome critical
            region of chromosome 21q22.2
  JOURNAL   J Biochem 122 (4), 872-877 (1997)
   PUBMED   9399594
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BU709449.1, AK077628.1 and BY483431.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB001990.1, AK077485.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 55.23 cM"
     Protein         1..297
                     /product="vacuolar protein sorting-associated protein 26C"
                     /note="Down syndrome critical region gene A; Down syndrome
                     critical region protein A homolog; Down syndrome critical
                     region protein 3 homolog; Down syndrome critical region
                     gene 3; DSCR3 arrestin fold containing"
                     /calculated_mol_wt=32839
     Region          1..283
                     /region_name="Arrestin_N"
                     /note="Arrestin (or S-antigen), N-terminal domain;
                     cl22903"
                     /db_xref="CDD:451447"
     CDS             1..297
                     /gene="Vps26c"
                     /gene_synonym="Dcra; Dscr3"
                     /coded_by="NM_007834.3:236..1129"
                     /db_xref="CCDS:CCDS28349.1"
                     /db_xref="GeneID:13185"
                     /db_xref="MGI:MGI:1206040"
ORIGIN      
        1 mgttldikik rankvyhage mlsgvvviss kdsvqhqgvs ltmegtvnlq lsaksvgvfe
       61 afynsvkpiq iinstidvlk pgkipsgkte vpfefpllvk gskvlyetyh gvfvniqytl
      121 rcdmrrslla kdltktcefi vhsapqkgkl tpspvdftit petlqnvker aslpkffirg
      181 hlnstncait qpltgelvve hsdaairsie lqlvrvetcg caegyardat eiqniqiadg
      241 dicrnlsvpl ymvfprlftc ptlettnfkv efevnvvvll hadhlitenf plklcrt
//
