LOCUS       NM_177151              13799 bp    mRNA    linear   ROD 01-OCT-2024
DEFINITION  Mus musculus vacuolar protein sorting 13B (Vps13b), mRNA.
ACCESSION   NM_177151 XM_981774 XM_986525
VERSION     NM_177151.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 13799)
  AUTHORS   Vacca,F., Yalcin,B. and Ansar,M.
  TITLE     Exploring the pathological mechanisms underlying Cohen syndrome
  JOURNAL   Front Neurosci 18, 1431400 (2024)
   PUBMED   39010945
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13799)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 13799)
  AUTHORS   Montillot,C., Skutunova,E., Ayushma, Dubied,M., Lahmar,A.,
            Nguyen,S., Peerally,B., Prin,F., Duffourd,Y., Thauvin-Robinet,C.,
            Duplomb,L., Wang,H., Ansar,M., Faivre,L., Navarro,N., Minocha,S.,
            Collins,S.C. and Yalcin,B.
  TITLE     Characterization of Vps13b-mutant mice reveals neuroanatomical and
            behavioral phenotypes with females less affected
  JOURNAL   Neurobiol Dis 185, 106259 (2023)
   PUBMED   37573958
REFERENCE   4  (bases 1 to 13799)
  AUTHORS   Assimopoulos,S., Hammill,C., Fernandes,D.J., Spencer Noakes,T.L.,
            Zhou,Y.Q., Nutter,L.M.J., Ellegood,J., Anagnostou,E., Sled,J.G. and
            Lerch,J.P.
  TITLE     Genetic mouse models of autism spectrum disorder present subtle
            heterogenous cardiac abnormalities
  JOURNAL   Autism Res 15 (7), 1189-1208 (2022)
   PUBMED   35445787
REFERENCE   5  (bases 1 to 13799)
  AUTHORS   Lhussiez,V., Dubus,E., Cesar,Q., Acar,N., Nandrot,E.F.,
            Simonutti,M., Audo,I., Lize,E., Nguyen,S., Geissler,A., Bouchot,A.,
            Ansar,M., Picaud,S., Thauvin-Robinet,C., Olivier-Faivre,L.,
            Duplomb,L. and Da Costa,R.
  TITLE     Cohen Syndrome-Associated Cataract Is Explained by VPS13B Functions
            in Lens Homeostasis and Is Modified by Additional Genetic Factors
  JOURNAL   Invest Ophthalmol Vis Sci 61 (11), 18 (2020)
   PUBMED   32915983
REFERENCE   6  (bases 1 to 13799)
  AUTHORS   Da Costa,R., Bordessoules,M., Guilleman,M., Carmignac,V.,
            Lhussiez,V., Courot,H., Bataille,A., Chlemaire,A., Bruno,C.,
            Fauque,P., Thauvin,C., Faivre,L. and Duplomb,L.
  TITLE     Vps13b is required for acrosome biogenesis through functions in
            Golgi dynamic and membrane trafficking
  JOURNAL   Cell Mol Life Sci 77 (3), 511-529 (2020)
   PUBMED   31218450
REFERENCE   7  (bases 1 to 13799)
  AUTHORS   Kim,M.J., Lee,R.U., Oh,J., Choi,J.E., Kim,H., Lee,K., Hwang,S.K.,
            Lee,J.H., Lee,J.A., Kaang,B.K., Lim,C.S. and Lee,Y.S.
  TITLE     Spatial Learning and Motor Deficits in Vacuolar Protein
            Sorting-associated Protein 13b (Vps13b) Mutant Mouse
  JOURNAL   Exp Neurobiol 28 (4), 485-494 (2019)
   PUBMED   31495077
REFERENCE   8  (bases 1 to 13799)
  AUTHORS   Koike,S. and Jahn,R.
  TITLE     SNAREs define targeting specificity of trafficking vesicles by
            combinatorial interaction with tethering factors
  JOURNAL   Nat Commun 10 (1), 1608 (2019)
   PUBMED   30962439
  REMARK    Publication Status: Online-Only
REFERENCE   9  (bases 1 to 13799)
  AUTHORS   Seifert,W., Holder-Espinasse,M., Kuhnisch,J., Kahrizi,K.,
            Tzschach,A., Garshasbi,M., Najmabadi,H., Walter Kuss,A., Kress,W.,
            Laureys,G., Loeys,B., Brilstra,E., Mancini,G.M., Dollfus,H.,
            Dahan,K., Apse,K., Hennies,H.C. and Horn,D.
  TITLE     Expanded mutational spectrum in Cohen syndrome, tissue expression,
            and transcript variants of COH1
  JOURNAL   Hum Mutat 30 (2), E404-E420 (2009)
   PUBMED   19006247
  REMARK    GeneRIF: Analysis of mouse tissues revealed ubiquitous expression
            of Coh1 homologous to human NM_152564 in all examined tissues but
            no prevalent alternative splicing.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC166356.1, AC122241.4, AC121598.3, AC144772.2 and AC157521.2.
            
            On Jul 12, 2018 this sequence version replaced NM_177151.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849382,
                              SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on single protein-coding
                                         transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-660               AC166356.1         57973-58632
            661-835             AC166356.1         58788-58962
            836-979             AC166356.1         65744-65887
            980-1100            AC166356.1         104366-104486
            1101-1268           AC166356.1         109163-109330
            1269-1450           AC166356.1         109971-110152
            1451-1625           AC166356.1         116965-117139
            1626-1891           AC166356.1         125568-125833
            1892-1987           AC166356.1         132425-132520
            1988-2110           AC166356.1         132893-133015
            2111-2248           AC166356.1         133478-133615
            2249-2336           AC166356.1         134540-134627
            2337-2528           AC166356.1         135385-135576
            2529-2698           AC166356.1         138953-139122
            2699-2893           AC166356.1         141812-142006
            2894-3018           AC166356.1         143470-143594
            3019-3200           AC166356.1         158738-158919
            3201-3335           AC122241.4         181001-181135
            3336-3509           AC122241.4         181892-182065
            3510-3619           AC121598.3         164738-164847       c
            3620-3767           AC121598.3         160381-160528       c
            3768-3895           AC121598.3         139385-139512       c
            3896-4130           AC121598.3         129543-129777       c
            4131-4351           AC121598.3         119089-119309       c
            4352-4555           AC121598.3         113102-113305       c
            4556-4727           AC121598.3         96883-97054         c
            4728-4842           AC121598.3         96263-96377         c
            4843-4909           AC121598.3         94443-94509         c
            4910-5318           AC121598.3         90526-90934         c
            5319-5430           AC121598.3         84541-84652         c
            5431-5634           AC121598.3         68003-68206         c
            5635-5761           AC121598.3         65482-65608         c
            5762-5905           AC121598.3         61955-62098         c
            5906-6593           AC121598.3         27094-27781         c
            6594-6731           AC144772.2         134667-134804       c
            6732-7139           AC144772.2         109588-109995       c
            7140-7342           AC144772.2         88210-88412         c
            7343-7547           AC144772.2         86413-86617         c
            7548-7732           AC144772.2         85962-86146         c
            7733-7929           AC144772.2         46071-46267         c
            7930-8111           AC144772.2         40395-40576         c
            8112-8461           AC144772.2         38853-39202         c
            8462-8623           AC144772.2         33444-33605         c
            8624-8779           AC144772.2         11009-11164         c
            8780-9043           AC144772.2         4626-4889           c
            9044-9127           AC144772.2         3988-4071           c
            9128-9303           AC144772.2         3634-3809           c
            9304-9474           AC144772.2         2784-2954           c
            9475-9676           AC144772.2         1607-1808           c
            9677-9865           AC144772.2         494-682             c
            9866-10012          AC157521.2         177184-177330       c
            10013-10296         AC157521.2         175429-175712       c
            10297-10424         AC157521.2         173215-173342       c
            10425-10624         AC157521.2         172837-173036       c
            10625-10743         AC157521.2         154829-154947       c
            10744-11546         AC157521.2         149270-150072       c
            11547-11723         AC157521.2         145269-145445       c
            11724-11894         AC157521.2         143002-143172       c
            11895-12071         AC157521.2         136856-137032       c
            12072-12174         AC157521.2         134813-134915       c
            12175-12424         AC157521.2         133929-134178       c
            12425-13799         AC157521.2         128990-130364       c
FEATURES             Location/Qualifiers
     source          1..13799
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 14.46 cM"
     gene            1..13799
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /note="vacuolar protein sorting 13B"
                     /db_xref="GeneID:666173"
                     /db_xref="MGI:MGI:1916380"
     exon            1..660
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            661..835
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     CDS             689..12670
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /note="vacuolar protein sorting-associated protein 13B;
                     cohen syndrome protein 1 homolog"
                     /codon_start=1
                     /product="intermembrane lipid transfer protein VPS13B"
                     /protein_id="NP_796125.2"
                     /db_xref="CCDS:CCDS49592.1"
                     /db_xref="GeneID:666173"
                     /db_xref="MGI:MGI:1916380"
                     /translation="MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKL
                     DVLEQELKLPFTFLSGHIHELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHES
                     CGSNSTNRSTAENTKSSIKPRRIQQAAPADPDLPPGYVQSLIRRVVNNVNIVINNLIL
                     KYVEDDIVLSVNITSAECYTVGELWDRAFMDISATDLVLRKAINFSDCTVCLDKRNAS
                     GKIEFYQDPLLYKCSFRTRLHFTYDNLNSKMPSVIKIHTLVESLKLSITDQQLPMFIR
                     IMQLGIALYYGEIGNFKDGETEDPPCLSKDTLANLTGTEEESRIDMQYPAPYKGQELY
                     SQDYEEPQGWVSWAWSFVPAIVSYDDGEEDDLGTDPASIMHQQKAQTLKDPIVSVGFY
                     CTKATVTFKLTEMQAENSYYSPQKVKSKEVLCWEQEGTTIEALMMGEPFFDCQIGFVG
                     CRAMCLKGILGVKDFEEHMNRSETEACFFICGENLSTKGLTYLTNSLFDYRSPENNGT
                     RAEFILDAAHHKETHTDIAGIQRFGAFYMDYLYTVEHSSGKGPTSQQDFPSGKNEDLG
                     IVQEKSTKSLVIGPLDCRLDSSAVHRVLKMIVCALEHEYEPYSRLKPESKDEKETVLD
                     PEEVSSLEEYIPTRHTSVTLLKCTCTVFMAEFNLLDCLLPVIMGGKNSSNVTNATNFQ
                     SLRPLPSIQILVDKINLEHSVPMYAEQLVHVVSSLNQPSDNLLHYCYVHCYLKVFGFQ
                     AGLTCLDHSGSYCLPAPIIPSFSTALYGKLLKLPALWTKRSQTVVTEGIFELPNLTIQ
                     ATRAQTLLLQAIYQSWSHIGNVSSSTVNEALMNEVFPMTGVKSKNPLPTLEGSIQNVE
                     LKYCSTSLVKCASGTLGSIKICAKAPGDSGKEKLIPLLQGPSDTRDLHSSKWLNESRK
                     PESLLAPDLIAFTIQVPQYMDYCHHSGAVFLCSVQGLAVNIDPILYTWVIYQPQKRAN
                     RHAQQQPVVAVPLVTSVNRRKEDELSIGSAPLGKQQSYQASEYASSPIKTKTVTESRP
                     VSVPVKAVLRVHEECRSPEDKMKEFIAILWNAVKSLTLQLDVQSCCVFIPNDNLPSPS
                     TIVSGDIPGTVRSWYHGQTSIPGTLVLCLPQIKIISAGHKYMEPLQEIPFVIPRPILE
                     EGDAFPWTISLHHFSIYTLLGKQVTLSLVEPMGCTSTLAVTSQKLLPVGPDGRHSFVV
                     CLHVDLESLEIKCSNPQVQLIYELADTMSKVWSKIQKRGNLSPSSVYPETVAGPIPGS
                     PVWSSVGTAPPDTSTCSPSADIGTTTEGDSVQAGDDSPFSDSVTLEQTTSNIGGSSGR
                     VSLWMQWVLPKATVKLFAPDLEKKGTEVCMVSELEDLSASIDVQDVYTKVKCKVESFS
                     IDHYQSRPGEGWQSGHFEGVFLQCKEKPVTTTKLLDGAHQQHGFLSLTYTKAVTKNVR
                     HKLTSRNERRSFYKLSEGLMDGSPHFLHEILLSAQAFDIVVCFPLLNAIASVFHTKLP
                     KTQREKRKSSGQPMRTHTLTSRNLPLIYINTSVIRIFVPQTEETQSTVAVNQAAKEDT
                     MVLKVGSIAMAPQADNPLGRSVLRKDIYQKALNLGILRDPGSEIEDRQYQIDLQSINI
                     GTAQWDQLKPEKGSGSGGVPTESERNSQNPALEWNMASSIQRHQERRAILTPILTDFS
                     VRITGAPAIIFTKIISQENLHMEEILVCGHSLEVNITTNLDFFLSVAQVQLLHQLIVA
                     NMTGLEPSTKATEISKQEQKKVDTFDGGTAETSSRYSGAQDSGIGSDSVKIRIVQIEQ
                     YSGASQHRIARPSHQSSIVKNLNFIPFDIFITASRISLMTYSSVALPKFKLPEQKEDG
                     KTGRTFLNLAEVDSDVAKPNQACVSMVTAEDPLSSSTSFSSGKKVRVLSLESLHASTR
                     SSARQALGVTVVRQPGRRGTGDLELDLFLHLIVSQPSLLLSCHHRKQRVEVSIFDAML
                     KGVPSDYTCTDPGKTLPEASDYNIVWLQTVPGETDSKSGIPPSLVTLHIKDFLNGPAD
                     IYLDVSKPLKANLSFTKLDQINHFLKKIKKAHSSAHSKETSTPSDSILNMDEPPVPKC
                     YRGKLSKTKVHCDEAQKTSFQENIWRAISCFQKVSVHTTQIVVSMETVPHPHKPCVLA
                     SLSNLNGSLTVKAAQKVPGASLGSSFLLSIHDVLLKTSLKERSRILIGPFSATVNLEA
                     KWCKHSGNPGPQQSIPKISMDLRGGLLQVFWGQEHLNCLALLHELFNGYLQEGKSEMP
                     VPESAPQMPSPVEKTQAFKTEQSSDDLRTGIFQYVQDAESLKLPGVYEVLFYNETEES
                     PGMMLWRYPEPRVLTLVRITPVPFNTTEDPDISTADLGDVLQVPCGLEYWDELQKVFV
                     AFQEFSLSESKVCELQLPDINLVHDQKKLVSSDLWRIVLNNNQNTTDDQSSASESGSQ
                     STCEPLVTPTALAACTRVDSCFTPWFVPSLCMSFQFAHLEFRLCHHLDQLGTASPQYL
                     QPFISDKNVPSELEYMIISFREPNLHLRQWNSGPVCQEIKFSSQMDCKLLECRNVTMQ
                     TVVKPFGICGQMALSSDGVQKLLDSTVIVDSVLVNFGQHVVHSLNTAIQAWQQNKCPE
                     VEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSWRSHKSPQLLHICIEGW
                     GNWRWSEPFTVDHAGTFIRTIQYKGRTASLIIKVRALSGVQKQIIICGRQIICSYLSQ
                     SIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENNELTELCVKAKGDEDWSRD
                     VCLEPKASEYSTVIQVPTSNSSIIYVWCTVLTLEPNSQVQQRMIVFSPLFIMRSHLPD
                     PIIIHLEKRSLGLSETQIIPGRGQENPLQNVEPDLVHHLTFQAREEYDPSDCAVPIST
                     ALIKQIATKIQPGGTVNEMLDEFYGPEKSQEPTWPYSNKDSDRNEQLSQWDSPMRVKL
                     SIWKPYVRTLLIELLPWALLINQSKWDLWLFEGEKIVLQVPAGKIIIPPNFQEAFQIG
                     IYWENTNTVHKTLAIKLVHNLTSPKWKDGGNGEVVTLDEEAFVDAEIRLGAFPGHQKL
                     CQFCISSMVQHGIQVIQIEDKTTVINNTPYQIVYKPHLAISNSYSGKEHCHVPDSATF
                     SICPGGEHPAVRSSSLPCWDVTPAVGSSELDTATLQKQILLGFSPVPGADSAQCWSLP
                     AIIGGEFPRQSVAVPFGTGRENGFCTRAIALTYQEHLGVTYITLSEDPSPRVVFHNRC
                     PVPMLMKENIRDIPKFDVYCKKIPPESSVHHELYHQIISYPDCKTKDLLPSLFLRIDS
                     MEEMTAEWSDPVDINSQGTQVVFLTGFGYVYVDIAQQCGTVFIILAPEGKAGPIFTST
                     SRALERMVTFRMFITQLSLAVSDDLTHQAPSELLRLTLDNVFLHVSPVPALLPGEEPP
                     SSFFQLYGVEVYCGDLQLDNQLYNKSNFHFAVLVCQGERTDPAQYSRVQSLLVSSKAL
                     EEYKENCFIKLCLTVSEGKDILLDVSEFTFELKPARLYVEDTFVYYIKTLFDTYLPPS
                     RMSGHHAQLFTGQQVLPVQVTQHAKALVNAVKLRKLLIQPVNLLISIHASLKLYIASD
                     HTPLSFSVFERGPVFTTARQLVHALAMHYAAGALFRAGWVVGSLEILGSPASLVRSIG
                     NGISDFFRLPYEGLTRGPGAFVSGVSRGTTSFVKHISKGALTSITNLATSLARNMGRL
                     SLDEEHYNRQEEWRRQLPESLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQKTSETQ
                     ASAGHKAKGVISGVGKGIMGVFTKPIGGAAELVSQTGYGILHGAGLSQLPKQRCQPTH
                     LYADQAPNSHVKYVWKMLQSLGRPEVHMALDVVLVRGSGQEHEGCLLLTSEVLFVVSI
                     SEDTQQQAFPITEISCAQDTKQNNLLTVQLKQPRVASDVEIDGARERLSEQQFKRLVD
                     YIAKTSCHLAPSCSSMQTCSVVAVEPPPATVKTYHYLVDPHFAQVFISKFTMVKNKAL
                     RKGFS"
     exon            836..979
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            980..1100
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            1101..1268
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            1269..1450
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            1451..1625
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            1626..1891
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            1892..1987
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            1988..2110
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            2111..2248
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            2249..2336
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            2337..2528
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            2529..2698
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            2699..2893
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            2894..3018
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            3019..3200
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            3201..3335
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            3336..3509
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            3510..3619
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            3620..3767
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            3768..3895
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            3896..4130
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            4131..4351
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            4352..4555
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            4556..4727
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            4728..4842
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            4843..4909
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            4910..5318
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            5319..5430
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            5431..5634
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            5635..5761
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            5762..5905
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            5906..6593
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            6594..6731
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            6732..7139
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            7140..7342
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            7343..7547
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            7548..7732
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            7733..7929
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            7930..8111
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            8112..8461
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            8462..8623
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            8624..8779
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            8780..9043
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            9044..9127
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            9128..9303
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            9304..9474
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            9475..9676
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            9677..9865
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            9866..10012
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            10013..10296
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            10297..10424
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            10425..10624
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            10625..10743
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            10744..11546
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            11547..11723
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            11724..11894
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            11895..12071
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            12072..12174
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            12175..12424
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     exon            12425..13799
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /inference="alignment:Splign:2.1.0"
     regulatory      13767..13772
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /note="hexamer: AATAAA"
     polyA_site      13799
                     /gene="Vps13b"
                     /gene_synonym="1810042B05Rik; 2310042E16Rik; 4732488H20;
                     C330002D13Rik; Coh1; D230005K13"
                     /note="major polyA site"
ORIGIN      
        1 agttcctctt tccagttctt ccagtagcca cggaaaacaa ccgtttctca attttctggg
       61 cttgaagaac gaaggctact tctcccgcct ccacggcacc ctgcgttcct gccgcctccg
      121 actactaagc ctcttgggca gtattgggtc acgtcccggc catcgccgtg tccctgcagc
      181 gccacttccg gatcgccggt gcttccactt taccggtccg catcccgcac cgagctcttc
      241 gtagagttaa ttcctaaccc agagcggtgg cagcggggat cccggcctag ccaagccgga
      301 gtcgtcccag gcaggcagac gcgcggggtc cttgtcccca ccgcggaaac ctgacggacg
      361 gcgaagcccg cacacccgga agtggcgcgg aacgcgtgag gcgtttccgc ggcggacgcc
      421 aggtacccgg aggaagagcg cacgccgccg ctctgtggcg tgtttacctt ggagcgggtg
      481 cggcggcggc ggcagcagcg ggcctgacgc cagctcggtc ctatggccgg agatccgcct
      541 gcgttccggg agtcgaccgc ctctggctgg gctgcgctag ggtaggagtg aagcaggacg
      601 tgctgtcctc ccacgcccgg gggccggccg cctccagcct ctctgcctac tcctcgtcag
      661 gatctgactt cgacgcttaa atttgaagat gctggagtcg tacgtaactc caattttaat
      721 gagttatgtg aatcgctata tcaagaactt aaaaccttca gatctccagc tttcactatg
      781 gggtggggac gtggttctca gcaaactcga gttaaagttg gacgttctgg aacaggaact
      841 gaaattacca ttcacttttt taagtggcca tatccatgaa ctgagaattc atgtaccatg
      901 gacaaaattg ggctccgaac ctgtggtaat taccatcaat acaatggaat gcatcttgaa
      961 acttaaagat ggaatacagg atgaccatga aagctgtggt tctaattcta ccaaccgtag
     1021 cactgctgag aacacaaaat catccataaa accccgaaga attcagcagg ctgctcctgc
     1081 agaccctgac ttaccaccag gatatgtgca gagtctgatt agacgagttg taaataatgt
     1141 aaacattgtt ataaataatc tcatactaaa atatgttgaa gatgacattg ttctttctgt
     1201 caacatcact tctgctgaat gctataccgt gggtgagtta tgggatcgtg cattcatgga
     1261 tatttctgca actgatctgg tgctgaggaa ggctatcaat ttttctgact gtacagtttg
     1321 tctcgataaa cgaaatgcta gtggcaaaat tgaattttac caggatcctt tattgtacaa
     1381 atgttctttt agaactcgcc tgcattttac atatgataac ctaaattcca agatgccatc
     1441 tgttattaaa atccatacct tggtagagag tctgaagctt tctatcacag accagcagct
     1501 acctatgttt atccgtataa tgcagcttgg gattgctctg tattatggag aaataggcaa
     1561 ctttaaagat ggtgaaacag aagacccgcc ctgtctcagt aaagatacac tagcaaacct
     1621 tacaggtact gaggaggaaa gtagaataga tatgcagtat cctgctccat acaaaggcca
     1681 agagttatat tcacaggact atgaggagcc tcagggatgg gtatcctggg cctggtcatt
     1741 tgttcctgca attgtgagtt atgatgatgg tgaggaagac gaccttggga ctgaccctgc
     1801 atcaatcatg catcaacaga aagctcaaac gctgaaggat cccattgttt ctgtaggctt
     1861 ttattgcaca aaggcgactg tgacttttaa actcactgaa atgcaagctg aaaatagcta
     1921 ttatagccca cagaaagtaa aatctaagga agttttgtgt tgggaacaag aaggaactac
     1981 aattgaggct cttatgatgg gagaaccttt ctttgattgt cagattggat ttgtaggttg
     2041 cagagccatg tgtctgaaag gaattctggg tgttaaagat tttgaggaac atatgaatag
     2101 gagtgaaact gaagcctgct tcttcatttg tggtgaaaat ttgagtacaa aaggtttgac
     2161 ataccttaca aattcattgt ttgattaccg gagtccagaa aacaatggta cccgtgcaga
     2221 gtttatcttg gatgcagctc accataagga gacacacact gacatagctg gcatacagag
     2281 gtttggtgcg ttttatatgg attacctgta tacagtggag cacagcagtg gcaaaggtcc
     2341 aacaagtcaa caagactttc cttcagggaa aaatgaggat ttgggaatag tccaagaaaa
     2401 gtctaccaag agtcttgtta tcgggcctct agattgccgt ctggacagca gtgcggtgca
     2461 tcgggttttg aagatgattg tttgtgctct ggaacatgaa tatgaaccat atagcaggct
     2521 aaaaccagaa agtaaggatg aaaaggaaac agtactggat cccgaggaag tgtcttcttt
     2581 ggaggaatat atccctactc ggcatacaag tgttactttg cttaagtgca cttgcacagt
     2641 ttttatggca gaattcaatt tacttgattg tttgcttcct gtcatcatgg gaggaaagaa
     2701 ctcgagtaac gtcacgaatg ccacaaactt ccagtcactt cggcctttgc catccattca
     2761 gatattggtg gataaaatta atttggaaca ttctgtccca atgtatgctg aacagttggt
     2821 ccatgtagtc agcagcctta atcaaccttc tgataatctt cttcattatt gttatgtcca
     2881 ctgctacctt aaggtgtttg gttttcaggc cggactgact tgcttggatc atagtggctc
     2941 ttactgctta cctgcaccaa ttatcccctc tttcagcaca gccctttatg ggaagcttct
     3001 gaaactccct gctctctgga ccaaaagatc tcagactgtt gtaactgagg gtatttttga
     3061 gctcccaaat ctcacaattc aagctacaag agcacagaca cttttgttgc aagcaatata
     3121 tcagagttgg tctcatattg gaaatgtcag ctcttcaaca gtaaatgaag ctttgatgaa
     3181 tgaagtcttc ccaatgacag gtgtgaaatc taagaatccc ctgccaactc ttgagggctc
     3241 aatccagaat gttgaactga agtactgcag cacatcattg gtcaaatgtg cctctgggac
     3301 cttgggatcc ataaaaattt gtgccaaagc cccaggtgac agtggaaaag agaagttgat
     3361 ccctttgctt cagggtcctt ctgacactag agaccttcac agttccaagt ggcttaatga
     3421 aagtagaaag cccgaatctc tcctagctcc agatttgata gcctttacca tccaggtccc
     3481 ccagtacatg gactactgcc atcactctgg tgctgtattt ctttgtagtg tacaaggact
     3541 cgctgttaac attgacccaa tactgtatac ttgggtcatc taccaaccac agaaacgagc
     3601 aaatagacat gcacaacagc agcctgtggt agctgtacct cttgtcactt cagttaacag
     3661 aaggaaagaa gatgaactgt ccattggaag tgccccattg ggaaagcagc agtcatatca
     3721 ggcctcagaa tatgccagca gcccaatcaa gacaaaaaca gtgacagagt ccagaccagt
     3781 gtcagttcct gtgaaggccg tgctgcgtgt tcatgaagaa tgtagaagtc ctgaagacaa
     3841 aatgaaagaa tttatcgcga tattatggaa tgcagtaaag agtctcacgc tacagcttga
     3901 tgtacagtct tgctgtgtat tcattccaaa tgacaacctg ccttccccaa gtacaattgt
     3961 gtctggtgac atccctggaa cagtaagaag ttggtaccat ggacaaacca gcataccagg
     4021 gacacttgtc ctgtgtttgc cgcaaataaa gattattagt gctggtcaca agtacatgga
     4081 acctctgcag gagattccgt ttgtgattcc ccggcccatc cttgaagagg gtgatgcatt
     4141 tccttggacc ataagcttgc atcatttcag catatatacc cttcttggaa agcaagtgac
     4201 tctttccctt gtggagccta tgggatgtac ctctactcta gcagtcacat ctcaaaagct
     4261 gcttcctgtg ggacccgatg gaaggcattc atttgttgtc tgtcttcatg ttgacttaga
     4321 gtcattagag ataaaatgct ctaatcccca ggtccagctc atttatgaat tggctgatac
     4381 gatgagtaaa gtctggagta aaattcagaa gagaggcaat cttagtccat cttcagtcta
     4441 cccagagaca gtggcagggc ctatccctgg ttctccagtt tggagcagcg taggtacagc
     4501 tccaccagac accagcacat gcagcccatc tgctgacata ggaactacta ctgagggaga
     4561 ttcggttcaa gctggtgatg attcgccatt ctcagactct gttaccttgg aacaaactac
     4621 cagtaacatt ggtgggtcca gcggccgtgt tagtctgtgg atgcagtggg tgctccccaa
     4681 agctactgtg aagctctttg ctccagacct tgaaaaaaaa ggcacagagg tctgcatggt
     4741 cagtgaactg gaagacctca gtgcatccat agacgtgcag gatgtgtaca ccaaagtcaa
     4801 gtgtaaggta gagagtttca gtatcgacca ctatcaaagc aggcctgggg aaggttggca
     4861 gtcaggacat tttgaaggag tgtttctgca gtgcaaagaa aaacctgtga caactacaaa
     4921 acttctagat ggtgctcatc agcagcatgg atttctttct ctgacataca ccaaagctgt
     4981 aacaaaaaat gtccgccaca agttaacctc aagaaatgag cgaagaagct tttataagtt
     5041 atctgaaggt ttaatggatg gctcgcctca ttttcttcat gaaattcttc tttctgcaca
     5101 agcgtttgat attgttgtgt gctttccttt acttaatgca attgcaagtg tatttcacac
     5161 taaactccca aagacccaaa gagagaaaag aaaatcttca ggtcagccca tgaggaccca
     5221 tacgctgact tcacgcaatt tacctttgat ttatatcaat acaagtgtca tcagaatttt
     5281 tgttccccaa acagaagaaa cacagtcaac tgttgcagtg aatcaggcag caaaggaaga
     5341 cacaatggtt ttgaaggttg gctctattgc catggctcct caggctgata atccgcttgg
     5401 cagatctgtc ctcaggaaag atatttacca gaaagcctta aacttaggaa ttcttcgaga
     5461 tcctggatca gaaattgaag acagacagta ccagatagac ctgcagtcca tcaatatcgg
     5521 cactgctcag tgggatcaac tcaaaccaga gaaaggcagt ggctcaggag gagtgccaac
     5581 agagagtgag aggaactctc aaaacccagc cctggagtgg aacatggcca gcagcataca
     5641 gcgtcatcaa gaaaggagag caattttgac acccatcttg acagattttt ctgtgcgaat
     5701 aactggagca cctgccatca ttttcaccaa aataatctcc caagaaaatc tgcatatgga
     5761 ggagatttta gtgtgtggcc attccttgga agtgaacata accacaaacc tggacttctt
     5821 cctaagtgtg gctcaggttc aactcttaca tcagttaata gtagcaaata tgactggatt
     5881 ggagccatca accaaggcta cagagatctc taaacaggaa cagaagaaag tggatacatt
     5941 tgatggaggc acagctgaaa cctcttcccg atacagtggt gctcaggaca gtggcattgg
     6001 cagtgacagt gttaaaatcc gcattgtgca aatagagcag tacagtggtg ccagtcagca
     6061 ccgcattgcc cggccctctc accagtcgtc aattgtgaaa aatcttaatt ttattccctt
     6121 tgacatattt attaccgcaa gtaggatctc cctaatgacc tattcctcgg tggccttacc
     6181 caaattcaaa ttaccagaac agaaagaaga tgggaaaaca ggcaggactt tcttaaatct
     6241 cgcagaagtt gattctgatg tagctaagcc taaccaggcg tgtgtttcca tggtgactgc
     6301 tgaagatccc ttaagcagta gcacttcttt ttcctcaggg aaaaaagtaa gggttctatc
     6361 gcttgaaagc ctccatgcat ccacaaggtc atctgccaga caagccctcg gagtcactgt
     6421 tgttcggcag cctggccgaa gaggaaccgg tgacttagaa ctagacctgt ttctccattt
     6481 gattgtgtcc cagccttcct tgcttctgag ttgtcaccac aggaaacaga gagtggaagt
     6541 atccatcttt gatgctatgc ttaaaggtgt accctctgac tacacatgta cagatcctgg
     6601 gaagaccctg cccgaagctt ctgactataa catcgtgtgg ctgcagactg tgcctggaga
     6661 aacagacagc aaaagtggga tcccaccgtc tctcgtcaca ctacacatca aagactttct
     6721 taatggacca gctgacatct acttggatgt atcaaagcct ttgaaagcaa acttaagttt
     6781 taccaaactc gatcagataa atcatttttt aaagaagata aaaaaggcac acagctctgc
     6841 acatagcaaa gagacctcca ccccgtcaga ctctatactg aatatggatg agcctcctgt
     6901 ccccaaatgt taccgtggaa agttgtcaaa gaccaaagtt cactgtgatg aagcacagaa
     6961 gacatcattt caagaaaaca tttggagagc catctcctgc tttcaaaaag tttctgtcca
     7021 tactacccaa atcgtggtct ccatggaaac tgtcccgcac cctcataagc catgtgtgtt
     7081 agcatcactg tcaaacctca atggaagcct tactgtcaaa gcagcacaaa aagtacctgg
     7141 cgcaagcctt ggatcatcat tcctcctcag catacatgat gttctcctta aaacaagcct
     7201 caaagaaaga agtcggattc ttataggacc attttctgct actgtcaatc tggaagctaa
     7261 atggtgtaaa cacagtggca atccagggcc acaacagtcc atacccaaaa tatccatgga
     7321 tttaagaggt ggtttgctac aggttttttg gggtcaagaa catttgaatt gcttggctct
     7381 tctgcatgaa ttattcaatg ggtatcttca ggagggaaag tctgaaatgc cagtacccga
     7441 atcagcaccc caaatgccat ctccagtgga aaagactcaa gcttttaaaa ctgaacaaag
     7501 ttcagatgac ctgcggacag gcatctttca gtatgtacag gacgctgaat ctttgaaact
     7561 ccctggtgtg tatgaagtct tgttttataa tgaaacagaa gagagcccag ggatgatgtt
     7621 gtggagatat ccagaacctc gagtgctcac ccttgtacga atcacgcctg tgcctttcaa
     7681 caccacagag gatccagata tcagcacagc agacctgggt gatgtgctgc aggtcccttg
     7741 tggtttggaa tattgggatg aactccagaa ggtttttgtt gcgtttcaag aattcagtct
     7801 gtctgaaagc aaagtttgtg aattgcagtt gccagatatc aaccttgtac atgaccagaa
     7861 gaaactggtg tcctcagatc tgtggagaat cgtcctaaac aacaatcaaa atacgacaga
     7921 tgaccaaagt tctgcaagtg aatccggttc tcaaagcact tgtgaaccac ttgtaactcc
     7981 aacagccctg gctgcttgca ccagagtgga ctcgtgtttt accccatggt tcgtcccatc
     8041 cctgtgcatg tccttccagt tcgctcatct ggaattccgt ctttgccatc acctggacca
     8101 actaggcaca gcttcaccac agtacctaca gccattcatt tctgataaaa atgtgccatc
     8161 tgaactggaa tacatgatca tttccttcag agaaccaaac ctgcatcttc ggcagtggaa
     8221 cagtggtcct gtctgccagg agatcaagtt ctcatctcag atggattgta aacttctgga
     8281 atgcagaaac gtcacgatgc aaactgtggt gaaacccttt ggcatctgtg gacagatggc
     8341 actttccagt gatggcgtgc agaagctgct ggactccacc gtgatagtgg actctgtgct
     8401 tgtcaacttc gggcagcatg tagttcattc cttaaacact gcaatacaag cgtggcaaca
     8461 gaacaaatgc cctgaggtag aagagttggt cttcagccac tttgtgatct gtaatgacac
     8521 acaggagaca ctgcggtttg gccaggtgga tactgatgaa aatattcttt tggcgagtct
     8581 ccacagtcac cagtacagct ggcgttctca taaatcccca cagctgttac acatctgtat
     8641 tgaaggctgg ggtaactggc gttggtcaga gcccttcact gtggaccatg ccggtacatt
     8701 tattagaaca attcagtaca agggtcgaac cgcttcactc atcatcaaag tccgagcact
     8761 cagtggagtg caaaaacaga ttatcatctg cggaagacag atcatctgta gctatttgtc
     8821 tcagagtata gaactgaaag ttgtccagca ttacattggt caagatggac aagctgtagt
     8881 tcgagaacac tttgattgcc tcacagccaa acagaagttg ccttcgtaca tattagaaaa
     8941 caacgaactg acagagctgt gtgtgaaggc taagggagac gaggactggt caagagatgt
     9001 gtgtctggaa cccaaagcct ctgagtatag cactgtcatc caggtgccta cttcaaacag
     9061 ttccattatt tatgtgtggt gcacagtttt gactttggaa cccaactctc aagttcagca
     9121 gcgaatgatc gtgttcagcc ctctctttat catgagaagt catcttccag accccattat
     9181 tatacatttg gaaaaaagaa gtctgggtct gagtgaaaca cagattattc caggaagagg
     9241 gcaggaaaat ccactgcaaa atgtcgaacc tgaccttgta catcacctga catttcaagc
     9301 acgggaagaa tatgaccctt ccgattgtgc ggttcccata tcaacagccc tcattaagca
     9361 aatagccact aagatacagc ctggaggcac agttaatgag atgcttgatg agttctatgg
     9421 gccagaaaag tcccaggagc ccacttggcc ttacagtaac aaagattctg acaggaatga
     9481 gcagctgagt cagtgggata gcccaatgcg agtcaaactg tcaatctgga aaccatatgt
     9541 tagaaccctg ttgatagaac tgctaccctg ggccctgctt atcaatcagt ccaagtggga
     9601 tctctggctg tttgaaggag agaagattgt tctacaagtt cctgctggca aaattattat
     9661 tcctcctaat tttcaggaag cttttcaaat tggaatttac tgggaaaata caaacactgt
     9721 gcacaagaca ttagcaatta aactggtcca taatctgaca tctccaaagt ggaaagatgg
     9781 cgggaatggt gaggtagtga cactggatga agaagcattt gttgatgctg aaatcagact
     9841 cggagctttc ccaggacatc agaagctgtg tcagttctgc atctcctcca tggtgcagca
     9901 cggcatacaa gtcattcaga ttgaagataa gactacagta atcaataaca cgccatatca
     9961 gatagtttat aagccacact tggccatctc taactcctat tctggaaagg agcattgtca
    10021 tgttccagac agtgctactt tcagcatttg tccagggggc gagcatcctg ccgtgagatc
    10081 cagctccctg ccttgctggg acgtcacgcc tgctgtgggg tcgtcagagc tggacacagc
    10141 cacgcttcag aaacagatac tgctggggtt ttctcctgta ccaggagccg acagcgctca
    10201 gtgctggagc ctgccagcca tcattggagg agagtttccc agacagagtg tagcagtgcc
    10261 ctttggaact gggagggaaa atggattctg caccagggca atagcactga catatcaaga
    10321 gcacttggga gtcacttaca taaccctctc cgaagaccca agtcctcgag tcgttttcca
    10381 caacagatgc ccagtaccga tgctcatgaa ggagaacatc agagatattc caaagtttga
    10441 tgtttattgc aaaaaaattc ctccggagag ttcggttcat catgagctat atcaccagat
    10501 tatcagttac ccagactgca agaccaagga cttacttccc agcctgtttc tgagaataga
    10561 ctcgatggaa gaaatgacag ccgagtggag tgaccctgtg gacatcaata gtcagggaac
    10621 acaggttgta ttcctcactg gctttggcta tgtgtatgtg gacatcgccc aacagtgtgg
    10681 cacagtcttt atcattctag ccccggaagg aaaagcagga cccatattta ccagcaccag
    10741 cagagctctg gagaggatgg tcactttcag gatgttcatc acccagttga gcctggcagt
    10801 gtctgacgac ctcacacacc aggcaccatc ggaactgcta aggctcaccc tggacaatgt
    10861 tttcctccac gtgtctcctg tgcctgctct cctcccaggg gaagagcctc cctccagctt
    10921 cttccagctt tacggtgtgg aagtctactg cggagacctg cagctggaca accagcttta
    10981 taacaagtct aatttccatt ttgctgtctt ggtctgccaa ggagagagaa cagaccctgc
    11041 tcagtattcc agggtgcaga gtctcctggt ctccagcaaa gccttggaag aatacaagga
    11101 gaattgcttc atcaaacttt gcctcactgt ctctgagggg aaggacatcc tcctcgatgt
    11161 cagcgagttc acctttgaac tgaagccagc acggctgtat gtggaggaca cctttgttta
    11221 ctacatcaaa actttgtttg acacctacct tcctcccagc aggatgtctg gtcaccatgc
    11281 acagctgttc acagggcagc aggtgctgcc tgtgcaggtg acacagcacg ccaaggcatt
    11341 ggtgaacgca gtgaagttac ggaagctgct catccagcca gtgaacctgc tcatcagcat
    11401 ccatgcctcc ctgaagctgt acatagcctc cgaccacacc cctctctcct tctctgtgtt
    11461 tgaaagagga ccagtgttca ccacagcaag gcagctggtg cacgcactgg ccatgcacta
    11521 tgctgctggg gctcttttca gagcaggctg ggtggtgggg tctctggaaa tcctcggcag
    11581 ccccgccagc ttagtgagaa gcattgggaa tgggatctcg gacttcttca ggcttccata
    11641 tgagggattg acccgaggcc caggagcctt cgtgagcgga gtctccagag ggaccacatc
    11701 attcgtcaag cacatttcca aaggtgcctt gacatccatc accaacttgg ccaccagcct
    11761 ggcccggaat atgggccggc tctcgctgga cgaggagcac tacaaccggc aggaggagtg
    11821 gcggcggcag ctccctgaga gcctaggtga aggactgcga cagggcctgt ccagactggg
    11881 catcagcctg ctcggtgcaa ttgctgggat agttgatcag ccaatgcaga actttcagaa
    11941 aacatctgag acccaggctt cagcaggaca taaggccaaa ggtgtcatct caggcgtggg
    12001 gaaaggaatc atgggggtat tcaccaaacc cattggggga gctgcagaac ttgtgtcaca
    12061 gactggctac ggtattttac atggagctgg actttctcag cttcccaaac aacggtgcca
    12121 accaacacat ctatatgctg accaggctcc aaacagccac gtcaaatatg tctggaaaat
    12181 gcttcagtct ttgggtagac cagaagtcca catggccttg gatgtggttc tggtgagggg
    12241 ttcaggccaa gagcatgaag ggtgcttgct gctgacatca gaagtactct ttgttgtaag
    12301 catcagtgaa gacacacaac aacaagcctt ccccatcaca gagatcagct gtgcacagga
    12361 caccaagcaa aacaacctac tcactgtgca gctcaagcaa ccaagagtag cctctgatgt
    12421 ggagattgat ggtgcccggg agaggctgtc agagcaacag tttaagaggc tcgtggacta
    12481 cattgcaaaa acatcttgtc acctggcccc cagctgctct tctatgcaga catgttctgt
    12541 ggtagctgtg gagcctcctc ctgccactgt taaaacatac cattatttgg tggacccaca
    12601 ttttgctcag gtcttcatta gtaaatttac catggtaaag aataaagccc tgaggaaagg
    12661 cttctcctga gtccccttta agggaggtgt ttggtttttg ctgtgcaaga ctgaattcta
    12721 acattcaaca tggacacaag gccagcactt tagttaaggc cacactagtt ttgtaggaat
    12781 ttacatctat gttctcccta aagaaacaaa caaaaattcc agatgggaga accaatgatc
    12841 agcaaaatcc tataaatgtt gtgttcttac catacacaga aaacctttct tctctatgcc
    12901 acaatcagaa gttctcactg gaattttaat ctattagtga tctgcatata gtaaaatgtg
    12961 gacaggccct agaaaacaga ccaagaaata aaactccacc acctctgtaa tatttagaac
    13021 tctgctgttt cactttaatt ttttacttaa ctacaatatc attcttttag taaaaaacaa
    13081 tgtgaattcc actcaaagtc tgtgttctac tgatttctag taagacagac ttttaactgc
    13141 tcaggtatat tttggaaagt ttgtgtttta ctaagctaaa gtaacacttt gtgtctaccg
    13201 acaagaacag aacatattgg ttataagttt gtttgcggat gagttaaaga ctccagcctt
    13261 aaggctgaca gtgacttcag tccagatagt tgctctgttg aattgatttg ataaagtctg
    13321 gagctatccc tagtatctgt taagtattat ttaacatcta gggagggctt tgatgcatga
    13381 cctggcatca ccactacctt caggagttag tgactctcag ggtctcatta cccactgatg
    13441 gtattcatgc acaggcctgc aatctgttcc ttcccttcaa ctgaaatgtg gcagtaagac
    13501 agggccactg atttcaaagg acactgacct acaacctcag tctgctgagc acacatccct
    13561 actacagcac tagtcctgga aaacaagtcc ttggtgaaca attcaaacca aatatgaaga
    13621 tcatctctgc aattggtcta ttacacattt aggaaaagaa catctttgtc aaactcaaga
    13681 acagttattt ttaagaatgt aaatatgtac tgattcttgt atggcttatg gtaattttac
    13741 atactgctgg aaattattat atacataata aaaggtattc ctgaatcact gaccgtgga
//
