LOCUS       NM_011979               1811 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus vanin 3 (Vnn3), mRNA.
ACCESSION   NM_011979
VERSION     NM_011979.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1811)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1811)
  AUTHORS   Karagianni,P., Moulos,P., Schmidt,D., Odom,D.T. and Talianidis,I.
  TITLE     Bookmarking by Non-pioneer Transcription Factors during Liver
            Development Establishes Competence for Future Gene Activation
  JOURNAL   Cell Rep 30 (5), 1319-1328 (2020)
   PUBMED   32023452
REFERENCE   3  (bases 1 to 1811)
  AUTHORS   Liu,X., Jiao,Y., Cao,Y., Deng,N., Ma,Y., Hasty,K.A., Kang,A.,
            Chen,H., Stuart,J.M. and Gu,W.
  TITLE     Decreased expression levels of Ifi genes is associated to the
            increased resistance to spontaneous arthritis disease in mice
            deficiency of IL-1RA
  JOURNAL   BMC Immunol 17 (1), 25 (2016)
   PUBMED   27480124
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1811)
  AUTHORS   Min-Oo,G., Fortin,A., Pitari,G., Tam,M., Stevenson,M.M. and Gros,P.
  TITLE     Complex genetic control of susceptibility to malaria: positional
            cloning of the Char9 locus
  JOURNAL   J Exp Med 204 (3), 511-524 (2007)
   PUBMED   17312006
  REMARK    GeneRIF: Lack of pantetheinase protein activity in tissues is
            associated with susceptibility to malaria and is linked to a
            complex rearrangement in the Vnn3 promoter region.
REFERENCE   5  (bases 1 to 1811)
  AUTHORS   Martin,F., Malergue,F., Pitari,G., Philippe,J.M., Philips,S.,
            Chabret,C., Granjeaud,S., Mattei,M.G., Mungall,A.J., Naquet,P. and
            Galland,F.
  TITLE     Vanin genes are clustered (human 6q22-24 and mouse 10A2B1) and
            encode isoforms of pantetheinase ectoenzymes
  JOURNAL   Immunogenetics 53 (4), 296-306 (2001)
   PUBMED   11491533
REFERENCE   6  (bases 1 to 1811)
  AUTHORS   Granjeaud,S., Naquet,P. and Galland,F.
  TITLE     An ESTs description of the new Vanin gene family conserved from fly
            to human
  JOURNAL   Immunogenetics 49 (11-12), 964-972 (1999)
   PUBMED   10501839
REFERENCE   7  (bases 1 to 1811)
  AUTHORS   Aurrand-Lions,M., Galland,F., Bazin,H., Zakharyev,V.M., Imhof,B.A.
            and Naquet,P.
  TITLE     Vanin-1, a novel GPI-linked perivascular molecule involved in
            thymus homing
  JOURNAL   Immunity 5 (5), 391-405 (1996)
   PUBMED   8934567
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC153973.33.
            
            On Sep 3, 2009 this sequence version replaced NM_011979.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ132103.1, BC111521.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849379
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-335               AC153973.33        71819-72153         c
            336-466             AC153973.33        71578-71708         c
            467-659             AC153973.33        67225-67417         c
            660-951             AC153973.33        58986-59277         c
            952-1322            AC153973.33        57617-57987         c
            1323-1496           AC153973.33        56348-56521         c
            1497-1811           AC153973.33        53772-54086         c
FEATURES             Location/Qualifiers
     source          1..1811
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 11.24 cM"
     gene            1..1811
                     /gene="Vnn3"
                     /note="vanin 3"
                     /db_xref="GeneID:26464"
                     /db_xref="MGI:MGI:1347055"
     exon            1..335
                     /gene="Vnn3"
                     /inference="alignment:Splign:2.1.0"
     CDS             123..1625
                     /gene="Vnn3"
                     /EC_number="3.5.1.92"
                     /note="vascular non-inflammatory molecule 3"
                     /codon_start=1
                     /product="vascular non-inflammatory molecule 3 precursor"
                     /protein_id="NP_036109.3"
                     /db_xref="CCDS:CCDS23734.1"
                     /db_xref="GeneID:26464"
                     /db_xref="MGI:MGI:1347055"
                     /translation="MASLHFPQWAVSFVFFAQAVGSMDTFIAAVYEHAVILPNKTESP
                     VSTEEALLLINKNIDILESAIKLAARQGAHIIVTPEDGIYGWIFTRETIYPYLEDIPD
                     PEVNWIPCRDPRRFGYTPVQERLSCLAKENSIYIMANIGDKKPCNATDPHCPPDGRYQ
                     YNTNVVFDSKGRLTARYHKYNLFEPEIQFDFPKDSELVTFDTPFGKFGIFTCFDIFSY
                     DPAVVVVKDTQVDSVLLPTAWYNTLPLLSAVPFHSVWARAMGVNVLAANTHNTSMHMT
                     GSGIYSPEAVRVYHYDMETESGQLLLSELRSRPRQHATPAEVNWSAYARTVKPFSSGQ
                     ADFPGKIYFDEFSFTKLTGSAGNYTVCQKDLCCHLTYKMSESRMDEVYVLGAFDGLHT
                     VEGQYYLQICTLLKCQTTNSRTCGEPVGSAFTKFEEFSLSGTFRTKYVFPQIVLSGSQ
                     LALERYYEVSRDGRLRSRGGAPLPILVMALYGRVFERDPPRLGQGPGKLQ"
     exon            336..466
                     /gene="Vnn3"
                     /inference="alignment:Splign:2.1.0"
     exon            467..659
                     /gene="Vnn3"
                     /inference="alignment:Splign:2.1.0"
     exon            660..951
                     /gene="Vnn3"
                     /inference="alignment:Splign:2.1.0"
     exon            952..1322
                     /gene="Vnn3"
                     /inference="alignment:Splign:2.1.0"
     exon            1323..1496
                     /gene="Vnn3"
                     /inference="alignment:Splign:2.1.0"
     exon            1497..1811
                     /gene="Vnn3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1792..1797
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Vnn3"
                     /note="hexamer: AATAAA"
     polyA_site      1809
                     /gene="Vnn3"
                     /note="major polyA site"
ORIGIN      
        1 gtgttccata atatattcac aggcagctgg ctggcatcac gacttgcgtc tgaatatttt
       61 tttttcccac tgagatacag tagaagaacc ttctgatttt cagagatcac tctattttaa
      121 ttatggcttc attacatttt cctcaatggg cagtgagttt tgtcttcttt gcccaggctg
      181 tgggttcaat ggacactttt attgctgctg tgtatgaaca tgctgttata ctgccaaaca
      241 aaactgaaag tcctgtttcc actgaagagg ctttgctcct gataaacaag aacatagaca
      301 ttttggagag tgcaatcaag ctggcagcca gacagggtgc acatatcatt gtgacgccag
      361 aagatggaat ctatggttgg atcttcacca gggagaccat ttacccctac ctagaggata
      421 taccagaccc tgaagtgaac tggattccct gtagagaccc taggaggttt ggctacacac
      481 cagtacagga gagactgagc tgccttgcca aggagaactc tatctatatt atggcaaata
      541 ttggggacaa gaagccatgc aatgctactg atcctcattg tcccccggat ggccgttacc
      601 aatataatac caatgtggtc ttcgattcta agggtaggct aacagcccgc taccataagt
      661 acaatctttt tgaaccagag attcagtttg atttccccaa agattcagag ctggtgacct
      721 ttgacacccc gtttgggaag tttggcatct tcacttgctt tgacattttc tcttatgacc
      781 cagctgtggt ggttgtgaag gacacccagg tcgacagtgt tctcttaccc acggcgtggt
      841 acaacaccct gcccctgctt tcagcagttc cattccattc ggtgtgggcc agagccatgg
      901 gggtcaacgt gcttgctgca aacacccaca acaccagcat gcatatgaca gggagtggaa
      961 tctacagccc ggaagctgtc cgagtgtacc actatgacat ggagacagag agtggccaac
     1021 tgctgctttc agagctgagg tctcggcctc gccagcacgc cacccctgca gaggttaact
     1081 ggagcgctta tgccaggact gtgaagccgt tctcatcggg gcaggcagac ttcccaggaa
     1141 agatttattt tgacgaattt agcttcacca agcttacagg aagtgctggc aattacacag
     1201 tttgccaaaa ggacctgtgc tgtcacctga cttacaagat gtctgagagc cgaatggacg
     1261 aggtgtatgt tctgggtgcc tttgatggac tccatacagt ggaaggccag tattacctac
     1321 agatatgtac attgctgaag tgtcaaacca ccaactcgag aacttgtggg gaacccgtgg
     1381 ggtcagcttt tacaaagttt gaagaattct ctctcagtgg cacctttcgg acaaaatatg
     1441 ttttcccaca gatcgtgcta agtgggagtc aacttgccct ggaaagatat tatgaagtct
     1501 caagagatgg acgtctgagg agtcgaggtg gagccccttt gcctatctta gtgatggccc
     1561 tgtatggaag agtgtttgag agagaccctc cgcgcttagg gcagggacct gggaagctgc
     1621 agtgatccct tcattgggga ccccacccgc ctgccctgac acaaggggcg gggtctgcac
     1681 aggattagcc tggcagagag cggggctcta agagcaagaa caaggagctg cagggttcca
     1741 ttaggagata cgatgtaagc tgctgaaaag gcaaagcaag tgagaggaaa caataaagta
     1801 aaaaagcaat t
//
