LOCUS       NM_175936               3276 bp    mRNA    linear   ROD 06-AUG-2023
DEFINITION  Mus musculus vomeronasal 2, receptor 81 (Vmn2r81), mRNA.
ACCESSION   NM_175936
VERSION     NM_175936.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3276)
  AUTHORS   Akiyoshi S, Ishii T, Bai Z and Mombaerts P.
  TITLE     Subpopulations of vomeronasal sensory neurons with coordinated
            coexpression of type 2 vomeronasal receptor genes are
            differentially dependent on Vmn2r1
  JOURNAL   Eur J Neurosci 47 (7), 887-900 (2018)
   PUBMED   29465786
REFERENCE   2  (bases 1 to 3276)
  AUTHORS   Leinders-Zufall T, Ishii T, Chamero P, Hendrix P, Oboti L, Schmid
            A, Kircher S, Pyrski M, Akiyoshi S, Khan M, Vaes E, Zufall F and
            Mombaerts P.
  TITLE     A family of nonclassical class I MHC genes contributes to
            ultrasensitive chemodetection by mouse vomeronasal sensory neurons
  JOURNAL   J Neurosci 34 (15), 5121-5133 (2014)
   PUBMED   24719092
REFERENCE   3  (bases 1 to 3276)
  AUTHORS   Henion TR, Madany PA, Faden AA and Schwarting GA.
  TITLE     beta3GnT2 null mice exhibit defective accessory olfactory bulb
            innervation
  JOURNAL   Mol Cell Neurosci 52, 73-86 (2013)
   PUBMED   23006775
REFERENCE   4  (bases 1 to 3276)
  AUTHORS   Ishii T and Mombaerts P.
  TITLE     Coordinated coexpression of two vomeronasal receptor V2R genes per
            neuron in the mouse
  JOURNAL   Mol Cell Neurosci 46 (2), 397-408 (2011)
   PUBMED   21112400
  REMARK    GeneRIF: the number of vomeronasal sensory neurons expressing a
            locus with a targeted deletion in the coding sequence of V2rf2 that
            is likely a null mutation, is similar to the number that express
            intact V2rf2
REFERENCE   5  (bases 1 to 3276)
  AUTHORS   Ishii T and Mombaerts P.
  TITLE     Expression of nonclassical class I major histocompatibility genes
            defines a tripartite organization of the mouse vomeronasal system
  JOURNAL   J Neurosci 28 (10), 2332-2341 (2008)
   PUBMED   18322080
REFERENCE   6  (bases 1 to 3276)
  AUTHORS   Young JM and Trask BJ.
  TITLE     V2R gene families degenerated in primates, dog and cow, but
            expanded in opossum
  JOURNAL   Trends Genet 23 (5), 212-215 (2007)
   PUBMED   17382427
REFERENCE   7  (bases 1 to 3276)
  AUTHORS   Loconto J, Papes F, Chang E, Stowers L, Jones EP, Takada T,
            Kumanovics A, Fischer Lindahl K and Dulac C.
  TITLE     Functional expression of murine V2R pheromone receptors involves
            selective association with the M10 and M1 families of MHC class Ib
            molecules
  JOURNAL   Cell 112 (5), 607-618 (2003)
   PUBMED   12628182
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC131066.8 and AC158634.5.
            
            On Aug 15, 2018 this sequence version replaced NM_175936.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ543404.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-232               AC131066.8         19912-20143         c
            233-524             AC131066.8         439-730             c
            525-1334            AC158634.5         82056-82865         c
            1335-1562           AC158634.5         80183-80410         c
            1563-1686           AC158634.5         76194-76317         c
            1687-3276           AC158634.5         56382-57971         c
FEATURES             Location/Qualifiers
     source          1..3276
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 39.72 cM"
     gene            1..3276
                     /gene="Vmn2r81"
                     /gene_synonym="EC1-V2R; EC1-VR2; V2rf2"
                     /note="vomeronasal 2, receptor 81"
                     /db_xref="GeneID:216144"
                     /db_xref="MGI:MGI:2684056"
     exon            1..232
                     /gene="Vmn2r81"
                     /gene_synonym="EC1-V2R; EC1-VR2; V2rf2"
                     /inference="alignment:Splign:2.1.0"
     CDS             18..2615
                     /gene="Vmn2r81"
                     /gene_synonym="EC1-V2R; EC1-VR2; V2rf2"
                     /note="EC1-V2R pheromone receptor"
                     /codon_start=1
                     /product="vomeronasal 2, receptor 81 precursor"
                     /protein_id="NP_787950.1"
                     /db_xref="CCDS:CCDS23976.1"
                     /db_xref="GeneID:216144"
                     /db_xref="MGI:MGI:2684056"
                     /translation="MLLSWLLIVWFLQMPTFTWIIATHICPTDTKYLIYSDGTVVIGA
                     FFPILHNSLVRTTTDWKYFPMDSDNYFGMSGRNYQLVLAMLFAINEINLNSHILPNTS
                     LGLEIYNLPAIGRNIFRTVFSWLTGLSSVIPNYTCRKESNSAATLTGVSWKTSETIWT
                     ILDLYKFPQLTFGPFDPVQIDRNQFQSLYQVAPKDTALLSGIASLMLHFNWNWVGLLI
                     PDDQRGAQFLSDFRKELDKTKICIAFVKTVLYLGETLLRLISQDHIHIIESSTADVIV
                     IYGPTSILLTLIENTYRTYNKKKIWVMSTKWFCPNLELYNMLELTHGALIFSPHYKEI
                     VGFKKFMLEATPIKYPEDIFLHLLWYWHFNCSFLHSECKIFENCLQNASLELLPGNIF
                     TMTMTEESYNVYNAVYAVAHSLHEETLSQIQFQPQANIDRTLLFPWQLHPFLKKIQVK
                     NSVGDHVVLDWKRKADPEYDITNIWNFPTGLSLLVKVGTFVPSAPKGEQLSMSEYMIS
                     WPIGFTEIPHSVCTESCNPGFRKVVLESKPTCCFDCTPCPDNEISNETGLDHCVHCPE
                     THYANAEKRHCLKKTVTFLYYNDPLGKGITLLSIGFSTLTALFIWVFVDHRGTPIIKA
                     NNRSLSYILLITLILCFLCPLLFIGLPNTATCIMQQYMFGLLFTVALSTVLAKTITVV
                     MAFKITAPGRKIRWLLTSQVPKFAIPICTLIQVLLSGIWLGTSPPFIDKDYHSEHGHI
                     IILCNKGSYIYFYCTLAYLGVMAFGSYLLAFLSRRLPDRFNESKSLAFSMLVFCSVWV
                     MFLPVYHSTSGKVMVAMEMFSILASSASILIIVFAPKCYIVLFRPELNILTHNRDKRH
                     HRSKTFLKT"
     exon            233..524
                     /gene="Vmn2r81"
                     /gene_synonym="EC1-V2R; EC1-VR2; V2rf2"
                     /inference="alignment:Splign:2.1.0"
     exon            525..1334
                     /gene="Vmn2r81"
                     /gene_synonym="EC1-V2R; EC1-VR2; V2rf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1335..1562
                     /gene="Vmn2r81"
                     /gene_synonym="EC1-V2R; EC1-VR2; V2rf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1563..1686
                     /gene="Vmn2r81"
                     /gene_synonym="EC1-V2R; EC1-VR2; V2rf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1687..3276
                     /gene="Vmn2r81"
                     /gene_synonym="EC1-V2R; EC1-VR2; V2rf2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagaaatatc acttaatatg ctgctctctt ggcttcttat cgtttggttt ttacagatgc
       61 caactttcac ctggatcatt gcaactcata tctgcccaac tgacacaaaa tacctaatat
      121 actctgatgg aactgttgtc attggtgcat tttttccaat tttacataat tcacttgtac
      181 gtacaacaac agattggaaa tactttccta tggattcaga taattatttt gggatgagtg
      241 gacgaaatta ccaactcgtt ttggccatgt tatttgccat caatgagatc aacttgaact
      301 cccatatttt accaaacacc tctcttggac ttgagattta taatctgcca gctattggaa
      361 ggaacatttt taggactgta ttctcttggc tcacgggttt gagtagcgtg atccctaatt
      421 atacatgtag aaaagaaagc aattcagctg ctacacttac tggagtatca tggaaaacat
      481 ctgaaacaat ttggaccata ttggatcttt acaaatttcc tcagcttact tttgggcctt
      541 ttgatcctgt tcagattgat agaaaccagt ttcaatctct ctaccaggtg gcccccaaag
      601 acacagctct attgtctggt attgcctctt tgatgcttca tttcaactgg aactgggtgg
      661 gactcctcat cccagatgac cagagaggtg ctcagtttct atcagacttt agaaaggagc
      721 tagacaaaac taaaatctgc atagcttttg tgaaaacagt attatatctg ggggaaaccc
      781 tacttcgttt gatatcacaa gatcatatcc acattataga atcatcaaca gcagatgtga
      841 ttgtaattta tggacccact tctattctat taactttaat agaaaataca tatagaacgt
      901 acaacaagaa aaaaatttgg gttatgagta caaaatggtt ttgcccaaat ttggaactat
      961 ataatatgtt agaattaacc catggggctc tgattttttc acctcattat aaggagattg
     1021 ttggtttcaa aaagtttatg ctagaagcca cccccatcaa gtacccagaa gatatttttc
     1081 ttcatttatt gtggtactgg catttcaact gctcattttt gcattctgaa tgtaaaatat
     1141 ttgaaaactg tctgcagaat gcctctttgg aattgttgcc aggaaatatt tttacaatga
     1201 ccatgactga agagagttac aatgtgtata atgctgtgta tgcagtggcc cacagtctgc
     1261 atgaggagac actcagtcaa atacaatttc aaccacaggc aaatattgat aggactctgt
     1321 tattcccctg gcagcttcac ccttttctga agaagattca agtgaaaaat tctgttgggg
     1381 accacgtggt tctggactgg aaaaggaagg cagatccaga gtatgatatt accaacattt
     1441 ggaatttccc aacaggtctt tcactattag tgaaagtggg tacatttgtt cccagtgctc
     1501 ccaaagggga acaattgtca atgtctgaat atatgattag ttggcctata ggatttacag
     1561 agattcctca ctctgtatgc actgagagct gcaatcctgg attcaggaaa gttgtcctgg
     1621 agagcaagcc tacctgttgc tttgattgca ctccttgccc agataatgag atttccaatg
     1681 aaacaggttt ggatcattgt gtgcactgtc cagaaactca ttatgcgaat gcagagaaga
     1741 gacactgcct gaagaaaaca gtaacttttc tgtactataa tgatcccctg gggaagggaa
     1801 tcacacttct ttccattgga ttctcaacac tcacagctct ttttatttgg gtatttgtag
     1861 accacagagg cactccaatc ataaaggcca ataatagatc tctcagttac atactgctca
     1921 tcactctcat cctctgtttc ctctgtccat tgctcttcat tggccttcca aatacagcaa
     1981 cgtgtataat gcaacagtac atgtttggac ttctgttcac tgtggcccta tccactgtgt
     2041 tagccaaaac catcactgta gttatggcct tcaagattac tgctccagga agaaagataa
     2101 ggtggttgct gacatcacag gtccctaaat ttgccattcc aatctgcaca ctgatacaag
     2161 tacttctgtc tggtatatgg ctgggaacat ctcctccatt tattgacaaa gattatcact
     2221 ctgaacatgg acacatcatc attctttgca acaagggctc atatatttac ttctactgca
     2281 ctctggctta cctgggagtc atggcctttg ggagttacct cttggctttc ttatccagga
     2341 gactgcccga cagatttaat gaatctaagt ccctggcttt cagcatgctt gtgttctgca
     2401 gtgtatgggt catgttcctc cctgtctacc acagcacctc tgggaaggtc atggtggcta
     2461 tggaaatgtt ctctatcttg gcttccagtg caagcattct tatcatagtc tttgctccta
     2521 agtgctacat tgttttgttt aggccagagt tgaacatact tactcacaac agggataaaa
     2581 gacaccacag gagcaaaact tttcttaaaa catagttcac atgattcttc aactaaattg
     2641 aatttttcta gatctcaacc agtttgactg tcgaatgtaa agttatggca tgatgttttt
     2701 atgatagttt tgtggatata cattctcacc aaatattcta tctgtagctt gattccctag
     2761 aatgccatgc tgaaataagt aacaaatttc acacactatg actgccacgt taaacttcat
     2821 accacaatat tcctcataac atttcatatt ttcaaatctt ttattttatc ttttaatctt
     2881 tttttcagta cagattttat ccccctcata gtccattctc tgtcagttcc acattccaca
     2941 cctcctaccc tgtctccatg aggatgtctc catcccagaa tcctccaccc caacaaacct
     3001 gcacactccc tggatcctcc tgttctttga ggattaggtg tatcttcaga gtccatcccc
     3061 aacagtcttc tgctgcatat gtgttgagga tctcatatta gctagtgtat gctgcctggt
     3121 ttgtagctca gtgtctgaga tctctggagt ccagcttagt tgagattgct ggttctccaa
     3181 cagggacacc ctaaaagttt atattaaggt gtacagcata tgtgcaatga attgatcctc
     3241 aagtttctaa taaaatgaaa tataatgttc aagaac
//
