LOCUS       NM_019917               2568 bp    mRNA    linear   ROD 02-APR-2024
DEFINITION  Mus musculus vomeronasal 2, receptor 26 (Vmn2r26), mRNA.
ACCESSION   NM_019917 XM_001006877
VERSION     NM_019917.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2568)
  AUTHORS   Hernandez-Clavijo,A., Sarno,N., Gonzalez-Velandia,K.Y., Degen,R.,
            Fleck,D., Rock,J.R., Spehr,M., Menini,A. and Pifferi,S.
  TITLE     TMEM16A and TMEM16B Modulate Pheromone-Evoked Action Potential
            Firing in Mouse Vomeronasal Sensory Neurons
  JOURNAL   eNeuro 8 (5) (2021)
   PUBMED   34433575
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2568)
  AUTHORS   Akiyoshi,S., Ishii,T., Bai,Z. and Mombaerts,P.
  TITLE     Subpopulations of vomeronasal sensory neurons with coordinated
            coexpression of type 2 vomeronasal receptor genes are
            differentially dependent on Vmn2r1
  JOURNAL   Eur J Neurosci 47 (7), 887-900 (2018)
   PUBMED   29465786
REFERENCE   3  (bases 1 to 2568)
  AUTHORS   Burton,S.D. and Urban,N.N.
  TITLE     Greater excitability and firing irregularity of tufted cells
            underlies distinct afferent-evoked activity of olfactory bulb
            mitral and tufted cells
  JOURNAL   J Physiol 592 (10), 2097-2118 (2014)
   PUBMED   24614745
REFERENCE   4  (bases 1 to 2568)
  AUTHORS   Dietschi,Q., Assens,A., Challet,L., Carleton,A. and Rodriguez,I.
  TITLE     Convergence of FPR-rs3-expressing neurons in the mouse accessory
            olfactory bulb
  JOURNAL   Mol Cell Neurosci 56, 140-147 (2013)
   PUBMED   23664818
REFERENCE   5  (bases 1 to 2568)
  AUTHORS   Leinders-Zufall,T., Ishii,T., Mombaerts,P., Zufall,F. and Boehm,T.
  TITLE     Structural requirements for the activation of vomeronasal sensory
            neurons by MHC peptides
  JOURNAL   Nat Neurosci 12 (12), 1551-1558 (2009)
   PUBMED   19935653
  REMARK    GeneRIF: the peptide presentation system provided by MHC molecules
            co-evolves with the peptide recognition systems expressed by T
            cells and vomeronasal sensory neurons
REFERENCE   6  (bases 1 to 2568)
  AUTHORS   Young,J.M. and Trask,B.J.
  TITLE     V2R gene families degenerated in primates, dog and cow, but
            expanded in opossum
  JOURNAL   Trends Genet 23 (5), 212-215 (2007)
   PUBMED   17382427
REFERENCE   7  (bases 1 to 2568)
  AUTHORS   Fleischer,J., Schwarzenbacher,K., Besser,S., Hass,N. and Breer,H.
  TITLE     Olfactory receptors and signalling elements in the Grueneberg
            ganglion
  JOURNAL   J Neurochem 98 (2), 543-554 (2006)
   PUBMED   16805845
REFERENCE   8  (bases 1 to 2568)
  AUTHORS   Del Punta,K., Puche,A., Adams,N.C., Rodriguez,I. and Mombaerts,P.
  TITLE     A divergent pattern of sensory axonal projections is rendered
            convergent by second-order neurons in the accessory olfactory bulb
  JOURNAL   Neuron 35 (6), 1057-1066 (2002)
   PUBMED   12354396
REFERENCE   9  (bases 1 to 2568)
  AUTHORS   Ryba,N.J. and Tirindelli,R.
  TITLE     A new multigene family of putative pheromone receptors
  JOURNAL   Neuron 19 (2), 371-379 (1997)
   PUBMED   9292726
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AY426342.1, AC122868.2 and AC147222.4.
            
            On Dec 14, 2006 this sequence version replaced NM_019917.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY426342.1, AF053985.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMN00849384
                                           [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1454              AY426342.1         1-1454
            1455-1455           AC122868.2         198145-198145
            1456-2530           AY426342.1         1456-2530
            2531-2531           AC147222.4         66896-66896         c
            2532-2568           AY426342.1         2532-2568
FEATURES             Location/Qualifiers
     source          1..2568
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 59.06 cM"
     gene            1..2568
                     /gene="Vmn2r26"
                     /gene_synonym="V2R1; V2r1b"
                     /note="vomeronasal 2, receptor 26"
                     /db_xref="GeneID:56552"
                     /db_xref="MGI:MGI:2678394"
     CDS             1..2568
                     /gene="Vmn2r26"
                     /gene_synonym="V2R1; V2r1b"
                     /note="vomeronasal 2, receptor, 1b; vomeronasal type-2
                     receptor 26; vomeronasal receptor Vmn2r26; vomeronasal
                     type-2 receptor 1b; putative pheromone receptor V2R1b;
                     tissue-type vomeronasal neurons putative pheromone
                     receptor V2R1"
                     /codon_start=1
                     /product="vomeronasal type-2 receptor 26 precursor"
                     /protein_id="NP_064301.2"
                     /db_xref="CCDS:CCDS20515.1"
                     /db_xref="GeneID:56552"
                     /db_xref="MGI:MGI:2678394"
                     /translation="MKLLTAFSPLVVLILFQEQISCYYLTKYASSGYYQDADFVIGGL
                     FSLRVTDGDTFISRSGVEDTSHIAEYVFADLIKYYQHILAMVFAIEKINKDPNILFNK
                     SLGFFLFNVNFIEMKAAEGSMALLSGESPPIPNYSCRPEKTDKLVAVIGGISTSISIQ
                     ISRVLSLYNVPQISYAPFDQILGTRVQLQSPYQFSMHTAALYQGIVQLLLYFTWIWVG
                     LVVPDDMRGELYLRDITKEMISHGICFAFAEKVTEYSSMDTVNWKHFMERLTLTPVII
                     TVGDTHSLLRIVYFVIFYNLSGNVWITTSDWYITTLPFEQNLIYTHFGGGLSFSFHMD
                     EILGFKDFLRSVQPRKYPHDIFIRHVWSSLFGCPHYYQHRLWDLSQCEPNGSLSTRPL
                     HAWDMNTSPYSYKVYAAVYAIAQALHEELSLRVEGDSSNKCLLQAPLPWKLHPFLQKG
                     QLGRSTNEENTVNKEVSAIKLDIFNYQSLQSGTEAHVKVGEFVFDSHSVQHLSLNDKI
                     ITWGKHRSQTPLSVCSQSCPFGFSKTAVEGKPFCCFDCVPCPDGEIANKTDMDQCIKC
                     PEDQYPNKQRNQCLPKIMVFLAHEDPLGTVLVSLAISLSAFSAMILGLFICYRETPIV
                     RANNRNLSYLLLISLKLCFSCSLMFIGQPRTVTCVLRQIIFGIVFSIVISAILAKTFI
                     VVMAFKAIKPGSILKMGMVTRLSNAIVCCGSIIQVCICAVWLGTYPPFPDVDMHSEFG
                     QIILWCNEGSTLAFYCVLGYLGFLASLSLLIAFLARRLPDSFNEAKTITFSMLVFCSV
                     WISFVPAYLSSKGKTMVAVEILSILASSAGLLGCIFLPKCYVILLKSGGHSRKKFFK"
     exon            1..218
                     /gene="Vmn2r26"
                     /gene_synonym="V2R1; V2r1b"
                     /inference="alignment:Splign:2.1.0"
     exon            219..516
                     /gene="Vmn2r26"
                     /gene_synonym="V2R1; V2r1b"
                     /inference="alignment:Splign:2.1.0"
     exon            517..1326
                     /gene="Vmn2r26"
                     /gene_synonym="V2R1; V2r1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1327..1551
                     /gene="Vmn2r26"
                     /gene_synonym="V2R1; V2r1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1552..1675
                     /gene="Vmn2r26"
                     /gene_synonym="V2R1; V2r1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1676..2568
                     /gene="Vmn2r26"
                     /gene_synonym="V2R1; V2r1b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgaaattac tcactgcttt ctctccccta gttgttctca ttttattcca ggaacaaatt
       61 tcttgttact acttaactaa atatgcttct tctggctact atcaagatgc agattttgtt
      121 attggaggac tcttttccct tagagtgact gatggagata catttataag tagatctggc
      181 gttgaagata caagccatat agcagaatat gtttttgcgg atctcattaa atattatcag
      241 cacattttag caatggtttt tgctatagaa aaaatcaaca aggacccaaa tattctattc
      301 aacaagtccc tgggattctt tctcttcaat gtcaacttca ttgagatgaa ggctgcggaa
      361 ggttctatgg ctttgctctc aggagagagc cccccaattc ctaactacag ctgcaggcct
      421 gaaaagactg ataagctggt tgcagtgata ggaggcattt caacatcaat atccattcag
      481 atctcccgag ttctaagtct ctacaacgtc ccacagatca gctatgctcc ttttgaccag
      541 attcttggga ccagagtcca gcttcagtct ccttatcagt tttcaatgca caccgcagct
      601 ctgtatcagg gaattgtcca actgctgtta tacttcactt ggatctgggt tggcctagtg
      661 gttccagatg atatgagggg agaactctat cttagggaca ttaccaagga gatgatcagc
      721 catggaattt gttttgcatt tgcagaaaag gttacagaat attcttctat ggacacagta
      781 aactggaaac attttatgga acgacttacc ttgacacctg ttatcattac tgttggagac
      841 acacattctc ttctgcgaat tgtctatttt gtcattttct ataatctttc aggtaatgtc
      901 tggatcacaa cttctgattg gtatatcacc acattaccct ttgaacagaa tttaatttat
      961 acacactttg gtggaggatt atcattttca tttcacatgg atgaaattct gggattcaag
     1021 gattttctca gaagtgttca acctagaaaa taccctcatg atatctttat ccggcatgta
     1081 tggtcaagct tatttggatg tccacattac taccaacaca gactctggga tctaagtcaa
     1141 tgtgagccaa atggcagcct gagcacacga cctctgcatg cttgggatat gaatacctca
     1201 ccctatagct acaaagtcta tgctgctgtg tatgccattg cccaggcact ccatgaggag
     1261 ctgtcactca gagtggaagg agactcatcc aataaatgtt tactccaggc tcctctccca
     1321 tggaagctcc atccattcct acaaaagggc caacttggga gaagcaccaa tgaggagaac
     1381 actgtgaaca aggaagtttc agcaatcaag cttgacatct ttaattacca gtctctacag
     1441 agcggtactg aagctcatgt gaaggttggc gagtttgtct ttgactctca cagtgttcag
     1501 catctttcac taaatgacaa aataataact tggggtaaac accgcagtca gactccttta
     1561 tctgtttgca gtcaaagttg tccatttgga tttagcaaaa cagctgttga ggggaaacca
     1621 ttctgttgtt ttgattgtgt cccatgtcca gatggagaaa ttgcaaataa aacagatatg
     1681 gatcaatgta tcaagtgtcc tgaagatcag tatccaaata aacagaggaa tcagtgtctc
     1741 cctaaaatta tggtattttt ggcccatgaa gatccactgg gaactgttct tgtctccttg
     1801 gccattagtt tatctgcctt ttcagctatg attctaggat tatttatctg ctatcgagaa
     1861 acacccattg tcagagcaaa taacagaaat ctcagttatc tcctcctcat ttctctaaag
     1921 ctctgtttct cttgctcact aatgttcatt ggccaaccta gaacagtcac ttgtgtcttg
     1981 agacaaatta tttttgggat tgtattttcc attgtcattt ctgctatctt ggcaaagacc
     2041 ttcattgtgg ttatggcttt caaagccatc aaaccaggaa gcatcttaaa aatggggatg
     2101 gtgacccgac tctcaaatgc catagtctgc tgtggttcca tcattcaagt gtgcatctgt
     2161 gcagtctggc tgggaacata tccccctttc cctgatgttg acatgcactc agagtttggt
     2221 caaatcattc tctggtgtaa cgaggggtcc acccttgctt tctattgtgt tctggggtac
     2281 ttgggctttc tggccagtct cagcttgctt attgcttttc tggctagaag gctacctgac
     2341 agcttcaatg aggcaaaaac aatcacattc agcatgctgg ttttctgcag tgtgtggatt
     2401 tcttttgtac cagcttacct gagctcgaaa ggcaaaacca tggtggccgt ggaaattctt
     2461 tcaattctag cctccagtgc tggcttactg ggatgtatat ttcttcccaa atgctatgtg
     2521 atcctactga agtcaggtgg tcattcaaga aagaagttct ttaaatga
//
