LOCUS       NM_019918               2739 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Mus musculus vomeronasal 2, receptor 1 (Vmn2r1), transcript variant
            1, mRNA.
ACCESSION   NM_019918
VERSION     NM_019918.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2739)
  AUTHORS   Gao,F., Wei,L., Li,J., Zeng,L., Wang,M., Lan,P., Liang,S.,
            Huang,X., Chen,L. and Jiang,H.
  TITLE     Circular RNA CircVmn2r1 Acts as a miR-223-3p Sponge to Promote
            Kidney Aging by Regulating NLRP3 Expression in Mice
  JOURNAL   J Gerontol A Biol Sci Med Sci 79 (7) (2024)
   PUBMED   38447057
  REMARK    GeneRIF: Circular RNA CircVmn2r1 Acts as a miR-223-3p Sponge to
            Promote Kidney Aging by Regulating NLRP3 Expression in Mice.
REFERENCE   2  (bases 1 to 2739)
  AUTHORS   Dietschi,Q., Tuberosa,J., Fodoulian,L., Boillat,M., Kan,C.,
            Codourey,J., Pauli,V., Feinstein,P., Carleton,A. and Rodriguez,I.
  TITLE     Clustering of vomeronasal receptor genes is required for
            transcriptional stability but not for choice
  JOURNAL   Sci Adv 8 (46), eabn7450 (2022)
   PUBMED   36383665
REFERENCE   3  (bases 1 to 2739)
  AUTHORS   Akiyoshi,S., Ishii,T., Bai,Z. and Mombaerts,P.
  TITLE     Subpopulations of vomeronasal sensory neurons with coordinated
            coexpression of type 2 vomeronasal receptor genes are
            differentially dependent on Vmn2r1
  JOURNAL   Eur J Neurosci 47 (7), 887-900 (2018)
   PUBMED   29465786
REFERENCE   4  (bases 1 to 2739)
  AUTHORS   Ishii,T. and Mombaerts,P.
  TITLE     Coordinated coexpression of two vomeronasal receptor V2R genes per
            neuron in the mouse
  JOURNAL   Mol Cell Neurosci 46 (2), 397-408 (2011)
   PUBMED   21112400
  REMARK    GeneRIF: great majority of vomeronasal sensory neurons that express
            intact V2rf2 coexpress Vmn2r1 immunoreactivity
REFERENCE   5  (bases 1 to 2739)
  AUTHORS   Fleischer,J., Schwarzenbacher,K. and Breer,H.
  TITLE     Expression of trace amine-associated receptors in the Grueneberg
            ganglion
  JOURNAL   Chem Senses 32 (6), 623-631 (2007)
   PUBMED   17556730
REFERENCE   6  (bases 1 to 2739)
  AUTHORS   Young,J.M. and Trask,B.J.
  TITLE     V2R gene families degenerated in primates, dog and cow, but
            expanded in opossum
  JOURNAL   Trends Genet 23 (5), 212-215 (2007)
   PUBMED   17382427
REFERENCE   7  (bases 1 to 2739)
  AUTHORS   Fleischer,J., Schwarzenbacher,K., Besser,S., Hass,N. and Breer,H.
  TITLE     Olfactory receptors and signalling elements in the Grueneberg
            ganglion
  JOURNAL   J Neurochem 98 (2), 543-554 (2006)
   PUBMED   16805845
REFERENCE   8  (bases 1 to 2739)
  AUTHORS   Martini,S., Silvotti,L., Shirazi,A., Ryba,N.J. and Tirindelli,R.
  TITLE     Co-expression of putative pheromone receptors in the sensory
            neurons of the vomeronasal organ
  JOURNAL   J Neurosci 21 (3), 843-848 (2001)
   PUBMED   11157070
REFERENCE   9  (bases 1 to 2739)
  AUTHORS   Ryba,N.J. and Tirindelli,R.
  TITLE     A new multigene family of putative pheromone receptors
  JOURNAL   Neuron 19 (2), 371-379 (1997)
   PUBMED   9292726
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AF053986.1 and AC126803.4.
            
            On Sep 7, 2006 this sequence version replaced NM_019918.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB267725.1, AF053986.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1274              AF053986.1         1-1274
            1275-1401           AC126803.4         60610-60736         c
            1402-1752           AF053986.1         1402-1752
            1753-1756           AC126803.4         47837-47840         c
            1757-2739           AC126803.4         45477-46459         c
FEATURES             Location/Qualifiers
     source          1..2739
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3"
     gene            1..2739
                     /gene="Vmn2r1"
                     /gene_synonym="Casrl1; EG56544; Gm34462; V2r83"
                     /note="vomeronasal 2, receptor 1"
                     /db_xref="GeneID:56544"
                     /db_xref="MGI:MGI:3645892"
     CDS             1..2739
                     /gene="Vmn2r1"
                     /gene_synonym="Casrl1; EG56544; Gm34462; V2r83"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; pheromone receptor V2Rx; vomeronasal type-2
                     receptor 1; calcium-sensing receptor like 1; putative
                     pheromone receptor V2R2; vomeronasal receptor Vmn2r1;
                     putative pheromone receptor V2R1; tissue-type vomeronasal
                     neurons putative pheromone receptor V2"
                     /codon_start=1
                     /product="vomeronasal type-2 receptor 1 isoform 1
                     precursor"
                     /protein_id="NP_064302.2"
                     /db_xref="CCDS:CCDS17384.1"
                     /db_xref="GeneID:56544"
                     /db_xref="MGI:MGI:3645892"
                     /translation="MASRQISLALGFLAFLWAVLGAQNKTEEVQCRLMAKFNLSGYVD
                     AKNHSLVIAGLFPIHSRIIPVDEAILEPVSPMCEGFNFRGFRWMKTMIHTIKEINERK
                     DILPNHTLGYQIFDSCYTISKAMESSLVFLTGQEEFKPNFRNSTGSTLAALVGSGGSS
                     LSVAASRILGLYYMPQVGYTSSCSILSDKFQFPSYLRVLPSDNLQSEAIVNLIKHFGW
                     VWVGAIAADDDYGKYGVKTFKEKMESANLCVAFSETIPKVYSNEKMQKAVKAVKTSTA
                     KVIVLYTSDIDLSLFVLEMIHHNITDRTWIATEAWITSALIAKPEYFPYFGGTIGFAT
                     PRSVIPGLKEFLYDVHPNKDPNDVLTIEFWQTAFNCTWPNSSVPYNVDHRVNMTGKED
                     RLYDMSDQLCTGEEKLEDLKNTYLDTSQLRITNNVKQAVYAIAHGLDHLSRCQEGQGP
                     FGSNQQCAYIPTFDFWQLMYYMKEIKFKSHEDKWVILDDNGDLKNGHYDVLNWHLDDE
                     GEISFVTVGRFNFRSTNFELVIPTNSTIFWNTESSRRPDSFCTQVCPPGTRKGIRQGQ
                     PICCFDCIPCADGYVSEKPGQRECDPCGEDDWSNAEKSKCVPKLVEFLAYEEALGFTL
                     VILSIFGALVLLAVTVVYVIHRHTPLVKANDRELSFLIQMSLVITVLSSLLFIGKPCN
                     WSCMARQITLALGFCLCLSSILGKTISLFFAYRISVSKTRLISMHPIFRKLIVLICVV
                     GEIGICAAYLVLEPPRMFKNIEIQNVKIIFECNEGSIEFLCSIFGFDVLLALLCFLTT
                     FVARQLPDNYYEGKCITFGMLVFFIVWISFVPAYLSTKGKFKVAVEIFAILASSYGLL
                     GCLFLPKCFIILLRPKRNTDETVGGRVPTVDRSIQLTSASVSSELNSTTVSTVLDE"
     exon            1..236
                     /gene="Vmn2r1"
                     /gene_synonym="Casrl1; EG56544; Gm34462; V2r83"
                     /inference="alignment:Splign:2.1.0"
     exon            237..528
                     /gene="Vmn2r1"
                     /gene_synonym="Casrl1; EG56544; Gm34462; V2r83"
                     /inference="alignment:Splign:2.1.0"
     exon            529..1401
                     /gene="Vmn2r1"
                     /gene_synonym="Casrl1; EG56544; Gm34462; V2r83"
                     /inference="alignment:Splign:2.1.0"
     exon            1402..1632
                     /gene="Vmn2r1"
                     /gene_synonym="Casrl1; EG56544; Gm34462; V2r83"
                     /inference="alignment:Splign:2.1.0"
     exon            1633..1756
                     /gene="Vmn2r1"
                     /gene_synonym="Casrl1; EG56544; Gm34462; V2r83"
                     /inference="alignment:Splign:2.1.0"
     exon            1757..2739
                     /gene="Vmn2r1"
                     /gene_synonym="Casrl1; EG56544; Gm34462; V2r83"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggccagca gacagataag cttagcttta ggatttcttg catttttgtg ggctgtattg
       61 ggtgctcaaa acaaaacaga ggaagtacaa tgcagattga tggccaagtt taatttgtct
      121 ggatatgtag atgccaaaaa tcattcactt gttattgcag gactgtttcc tatccactcc
      181 agaatcatcc cagtagatga agctattttg gagccggtat cacccatgtg tgaagggttt
      241 aatttccggg gtttccgatg gatgaaaacc atgatccaca ccattaagga gattaatgag
      301 aggaaggaca ttttgcccaa ccatactctg ggctaccaga tctttgattc ctgctatacc
      361 atctccaaag caatggagtc atctttggtg tttcttactg ggcaggaaga attcaaaccc
      421 aattttagaa atagcactgg atcaactcta gcagcactgg ttggatcagg gggatcatct
      481 ttgtcagttg ctgcttcacg aattctaggg ttgtattata tgcctcaggt gggctatact
      541 tcttcctgct caattcttag tgacaaattc cagtttccat cttatcttcg tgtactaccc
      601 agtgataacc tccagtctga ggccatagtg aatctcatca aacacttcgg ttgggtctgg
      661 gtaggtgcta ttgcagctga tgatgattat gggaaatatg gagtaaaaac ttttaaggaa
      721 aaaatggaga gtgccaacct ctgtgttgct ttctctgaaa ccattcccaa agtctactcc
      781 aatgagaaaa tgcagaaggc tgttaaggca gtaaagactt ccactgccaa agtcattgtg
      841 ctttatactt ctgacattga cctcagcctg tttgtgctgg aaatgattca tcataacata
      901 actgacagga catggatagc caccgaagcc tggattacct ctgctctcat tgcaaagcct
      961 gagtatttcc cctattttgg tggaactatt ggatttgcaa caccaagaag tgttatacca
     1021 ggactaaaag aatttcttta tgatgtacac cctaacaagg atccaaatga tgtcttgacc
     1081 attgaattct ggcaaactgc ttttaactgt acctggccca acagcagtgt tccttataac
     1141 gtggatcaca gagtgaatat gactgggaaa gaagacagac tgtatgacat gtctgatcag
     1201 ctctgcactg gagaggagaa gctggaagat ctgaaaaaca cctatctgga tacatcacag
     1261 ctaagaatta caaacaatgt caaacaagct gtatatgcta tagctcatgg cctggatcat
     1321 ctcagcagat gtcaagaagg gcagggacca tttggttcaa atcagcaatg tgcatatata
     1381 cctacctttg atttctggca gctaatgtac tatatgaaag aaattaaatt taaatcacat
     1441 gaggataaat gggtaattct ggatgataat ggagatttga aaaatggaca ctatgatgtc
     1501 ctaaactggc acttagatga tgagggagaa atttcctttg tgacagttgg gagatttaac
     1561 tttagatcta caaactttga gcttgttatt ccaacgaatt ctacaatatt ttggaacact
     1621 gagtcatcaa ggcgtccaga ttcattttgc acacaagtgt gtcctccagg gacccggaag
     1681 gggattcgtc aggggcaacc catatgctgc tttgattgca tcccatgtgc tgatggatat
     1741 gtgtcagaga aaccaggaca gagggaatgt gatccatgcg gtgaagatga ctggtccaat
     1801 gcagagaaga gcaagtgtgt gccaaagctt gtggaattcc tcgcttatga agaggcactg
     1861 gggttcactc ttgtcatcct gtccatcttt ggggcacttg tcctcttggc agtaactgtt
     1921 gtgtatgtga tccacagaca cactccattg gtgaaagcca atgaccggga gctgagcttc
     1981 ctcattcaga tgtctctggt catcactgtg ctgtcttcct tgctgttcat aggcaagcca
     2041 tgcaactggt cctgcatggc ccgccagatc actctggcac tcggcttttg cctttgtctg
     2101 tcttccattc ttggaaagac tatttcactc ttttttgcct ataggatttc tgtatctaaa
     2161 acccgtctta tatccatgca ccccattttt cgaaaattaa ttgtactgat ctgcgttgta
     2221 ggggagattg gtatatgtgc agcatacttg gtgttggagc ctccaaggat gttcaagaac
     2281 attgaaattc aaaatgtaaa gatcatcttt gaatgcaatg aaggttctat agagtttctg
     2341 tgctccatat ttgggtttga tgttctcctg gctctgctgt gttttcttac aacctttgtg
     2401 gctcgccagc tgccagataa ctattatgaa gggaaatgta tcacttttgg gatgctggtc
     2461 tttttcattg tctggatctc ttttgtccct gcttacttga gcaccaaagg caaattcaaa
     2521 gtggctgtgg aaatatttgc cattttggca tctagctatg gcttgttagg ctgtctattt
     2581 cttcccaagt gcttcattat cttgctgagg ccaaagagga acactgatga aactgttggt
     2641 ggaagagtcc ccactgttga caggagcatc cagctgacct cagcttctgt gagcagtgag
     2701 cttaacagca ccacagtgtc cactgttcta gatgagtag
//
