LOCUS       NM_001347055            6965 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus vir like m6A methyltransferase associated (Virma),
            transcript variant 2, mRNA.
ACCESSION   NM_001347055 XM_006538160
VERSION     NM_001347055.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6965)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6965)
  AUTHORS   Wang,L., Zou,Y., Huang,Z., Wang,W., Li,J., Bi,J. and Huo,R.
  TITLE     KIAA1429 promotes infantile hemangioma regression by facilitating
            the stemness of hemangioma endothelial cells
  JOURNAL   Cancer Sci 114 (4), 1569-1581 (2023)
   PUBMED   36572002
  REMARK    GeneRIF: KIAA1429 promotes infantile hemangioma regression by
            facilitating the stemness of hemangioma endothelial cells.
REFERENCE   3  (bases 1 to 6965)
  AUTHORS   Xu,C.L., Tan,Q.Y., Yang,H., Li,C.Y., Wu,Z. and Ma,Y.F.
  TITLE     Melatonin enhances spermatogonia activity through promoting
            KIAA1429-mediated m6A deposition to activate the PI3K/AKT signaling
  JOURNAL   Reprod Biol 22 (4), 100681 (2022)
   PUBMED   35987159
  REMARK    GeneRIF: Melatonin enhances spermatogonia activity through
            promoting KIAA1429-mediated m[6]A deposition to activate the
            PI3K/AKT signaling.
REFERENCE   4  (bases 1 to 6965)
  AUTHORS   Ito-Kureha,T., Leoni,C., Borland,K., Cantini,G., Bataclan,M.,
            Metzger,R.N., Ammann,G., Krug,A.B., Marsico,A., Kaiser,S.,
            Canzar,S., Feske,S., Monticelli,S., Konig,J. and Heissmeyer,V.
  TITLE     The function of Wtap in N6-adenosine methylation of mRNAs controls
            T cell receptor signaling and survival of T cells
  JOURNAL   Nat Immunol 23 (8), 1208-1221 (2022)
   PUBMED   35879451
REFERENCE   5  (bases 1 to 6965)
  AUTHORS   Wu,Y., Xu,X., Qi,M., Chen,C., Li,M., Yan,R., Kou,X., Zhao,Y.,
            Liu,W., Li,Y., Liu,X., Zhang,M., Yi,C., Liu,H., Xiang,J., Wang,H.,
            Shen,B., Gao,Y. and Gao,S.
  TITLE     N6-methyladenosine regulates maternal RNA maintenance in oocytes
            and timely RNA decay during mouse maternal-to-zygotic transition
  JOURNAL   Nat Cell Biol 24 (6), 917-927 (2022)
   PUBMED   35606490
REFERENCE   6  (bases 1 to 6965)
  AUTHORS   Perez-Garcia,V., Fineberg,E., Wilson,R., Murray,A., Mazzeo,C.I.,
            Tudor,C., Sienerth,A., White,J.K., Tuck,E., Ryder,E.J., Gleeson,D.,
            Siragher,E., Wardle-Jones,H., Staudt,N., Wali,N., Collins,J.,
            Geyer,S., Busch-Nentwich,E.M., Galli,A., Smith,J.C., Robertson,E.,
            Adams,D.J., Weninger,W.J., Mohun,T. and Hemberger,M.
  TITLE     Placentation defects are highly prevalent in embryonic lethal mouse
            mutants
  JOURNAL   Nature 555 (7697), 463-468 (2018)
   PUBMED   29539633
REFERENCE   7  (bases 1 to 6965)
  AUTHORS   Wen,J., Lv,R., Ma,H., Shen,H., He,C., Wang,J., Jiao,F., Liu,H.,
            Yang,P., Tan,L., Lan,F., Shi,Y.G., He,C., Shi,Y. and Diao,J.
  TITLE     Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic
            Stem Cell Self-Renewal
  JOURNAL   Mol Cell 69 (6), 1028-1038 (2018)
   PUBMED   29547716
REFERENCE   8  (bases 1 to 6965)
  AUTHORS   Yue,Y., Liu,J., Cui,X., Cao,J., Luo,G., Zhang,Z., Cheng,T., Gao,M.,
            Shu,X., Ma,H., Wang,F., Wang,X., Shen,B., Wang,Y., Feng,X., He,C.
            and Liu,J.
  TITLE     VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near
            stop codon and associates with alternative polyadenylation
  JOURNAL   Cell Discov 4, 10 (2018)
   PUBMED   29507755
  REMARK    Publication Status: Online-Only
REFERENCE   9  (bases 1 to 6965)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
REFERENCE   10 (bases 1 to 6965)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL772170.14 and AL732538.6.
            
            On Nov 15, 2016 this sequence version replaced XM_006538160.3.
            
            Transcript Variant: This variant (2) lacks an alternate in-frame
            exon compared to variant 1. The resulting isoform (2) has the same
            N- and C-termini but is shorter compared to isoform 1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK122509.1, SRR10223970.6019.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-148               AL772170.14        192803-192950
            149-264             AL732538.6         8020-8135
            265-351             AL732538.6         11996-12082
            352-400             AL732538.6         14565-14613
            401-569             AL732538.6         18698-18866
            570-692             AL732538.6         20210-20332
            693-965             AL732538.6         21163-21435
            966-2106            AL732538.6         26284-27424
            2107-2595           AL732538.6         32182-32670
            2596-2750           AL732538.6         34361-34515
            2751-2833           AL732538.6         36109-36191
            2834-2927           AL732538.6         39603-39696
            2928-3472           AL732538.6         39851-40395
            3473-3708           AL732538.6         40904-41139
            3709-3961           AL732538.6         41794-42046
            3962-4179           AL732538.6         44084-44301
            4180-4312           AL732538.6         47445-47577
            4313-4465           AL732538.6         53166-53318
            4466-4626           AL732538.6         53737-53897
            4627-4723           AL732538.6         55363-55459
            4724-4890           AL732538.6         58087-58253
            4891-5222           AL732538.6         59225-59556
            5223-5366           AL732538.6         61987-62130
            5367-6965           AL732538.6         62801-64399
FEATURES             Location/Qualifiers
     source          1..6965
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 5.11 cM"
     gene            1..6965
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /note="vir like m6A methyltransferase associated"
                     /db_xref="GeneID:66185"
                     /db_xref="MGI:MGI:1913435"
     exon            1..148
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /inference="alignment:Splign:2.1.0"
     exon            149..264
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /inference="alignment:Splign:2.1.0"
     exon            265..351
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /inference="alignment:Splign:2.1.0"
     exon            352..400
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /inference="alignment:Splign:2.1.0"
     exon            401..569
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /inference="alignment:Splign:2.1.0"
     exon            570..692
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /inference="alignment:Splign:2.1.0"
     exon            693..965
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /inference="alignment:Splign:2.1.0"
     exon            966..2106
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /inference="alignment:Splign:2.1.0"
     exon            2107..2595
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /inference="alignment:Splign:2.1.0"
     exon            2596..2750
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /inference="alignment:Splign:2.1.0"
     exon            2751..2833
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /inference="alignment:Splign:2.1.0"
     exon            2834..2927
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /inference="alignment:Splign:2.1.0"
     exon            2928..3472
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /inference="alignment:Splign:2.1.0"
     exon            3473..3708
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /inference="alignment:Splign:2.1.0"
     exon            3709..3961
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /inference="alignment:Splign:2.1.0"
     exon            3962..4179
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /inference="alignment:Splign:2.1.0"
     exon            4180..4312
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /inference="alignment:Splign:2.1.0"
     exon            4313..4465
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /inference="alignment:Splign:2.1.0"
     exon            4466..4626
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /inference="alignment:Splign:2.1.0"
     exon            4627..4723
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /inference="alignment:Splign:2.1.0"
     exon            4724..4890
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /inference="alignment:Splign:2.1.0"
     exon            4891..5222
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /inference="alignment:Splign:2.1.0"
     exon            5223..5366
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /inference="alignment:Splign:2.1.0"
     exon            5367..6965
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5683..5688
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /note="hexamer: AATAAA"
     polyA_site      5707
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /note="major polyA site"
     regulatory      6487..6492
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /note="hexamer: AATATA"
     polyA_site      6511
                     /gene="Virma"
                     /gene_synonym="1110037F02Rik; 4930422M05Rik; Kiaa1429;
                     mKIAA1429"
                     /note="major polyA site"
ORIGIN      
        1 agttttcccc ctagctggag cctcggcctg ggaggttgga gagctgcccc ggaagtcatc
       61 tcccggtccc ccgcccgcgg cagacatggc ggtggactcg tctatggagc tgctattttt
      121 agatactttt aaacatccga gcgctgagca aagttctcat atagatgtgg ttcgttttcc
      181 gtgtgtggtt tatatcaatg aagtccgagt tatacccccg ggagtacgag cccatagtgg
      241 cttacctgac aacagagcat atggggaaac atctcctcac acatttcaac ttgacttatt
      301 cttcaataat gtaagcaaac caagtgctcc agtttttgat aggttgggaa gcctggaata
      361 tgatgagaat acgtctatca tctttagacc aaactcgaag gtaaatactg atggtctggt
      421 actaagaggc tggtacaact gtctgaccct ggcaatatat ggatcggtag atagagtgat
      481 aagccatgac agagactctc caccacctcc acctccacct ccacctcctc cccagccaca
      541 gccgactttg aaaaggaatc taaagcatgc tgatggtgag aaggaagatc agtttaatgg
      601 aagtcctcca agaccccagc cacggggacc aagaactcct cctggacctc ctccacctga
      661 tgacgatgag gacgacccta tgtctttgcc agtgtctggt gacaaagaag aggatgttcc
      721 ccatcgagaa gattactttg agcccatttc tcctgatagg aattctgtcc cgcaggaagg
      781 tcagtattcc gatgaaggag aggtagaaga ggaaccgcaa gaagagggag aagatgatga
      841 agatgatgtg gatgtagagg aagaagagga tgaagatgag gatgactgcc atacagtaga
      901 tagtatccct gatgatgagg aagaagatga agaggaagaa ggtgaagagg atgaagaagg
      961 tgaaggggac gatggctacg agcagatctc tagtgatgaa gatggaattg ctgacttgga
     1021 acgtgaaaca ttcaagtatc caaacttcga tgttgagtat actccagaag acctggcatc
     1081 tgtccctcct atgacgtatg acccgtatga cagggagctg gcaccactct tgtatttcag
     1141 ctgtccatac aaaactactt ttgaaattga aatcagtaga atgaaggatc aaggtccaga
     1201 taaagagaat tcaggggcag tagaagcctc ggtgaagtta actgaactgc tagacctgta
     1261 tcaggaagac aggggtgcaa agtgggtgac ggctctagaa gaaattccaa gtctaattat
     1321 aaaaggatta agctatttgc aattgaaaaa cacagaacaa gactcccttg gccagttggt
     1381 agactggaca atgcaagctt taaatttaca agtagccttt cgacagccca tagccttaaa
     1441 tgtccgacag ctcaaagctg ggaccaagct agtgacctca ttagcagaat gtggggctcc
     1501 aggagtcaca gaattgctac aagcaggagt gatcaatgta ttgtttgatc tcttatttgc
     1561 tgatcatgtc tcatcttccc ttaagttaaa tgcttttaaa gctttggaca gtgtcattag
     1621 catgacagaa ggaatggagg cttttttaag aagcacccaa aatgagaaaa gtggctatca
     1681 aagacttctg gaactcatac ttctggatca gactgtgagg gttgtcactg ctggctcagc
     1741 tattcttcaa aaatgccatt tctatgaaat cttgtcagag attaaaagac ttggtgacca
     1801 catagcagag aagacttcag ctgttcctaa ccacagtgag cctgaccagg acacagatgc
     1861 tgtgctggag agagcaaatc ccgattatga gaatgaagta gaagcttcta tggacatgga
     1921 tcttttggag tcctcaatta taagtgaagg tgaaatagaa aagcttacta atctcttaga
     1981 ggaggttttt catgtcatgg aaactgcacc tcatacaatg acccaacctc ctgtcaagtc
     2041 tttccccaca atagcccgga ttaccgggcc tccagagcgg gatgacccgt accctgtcct
     2101 ctttaggtat cttcacagcc atcacttcct ggagttggtc accttgcttc tgtcgattcc
     2161 aataacaagt gcccatcagg gtgtactgca agccacgaag gatgttttaa agtttcttgc
     2221 acagtcacaa aagggccttc tcttttttat gtcagaatat gaagcgacaa acttgttgat
     2281 ccgagctctg tgccaccttt atgatcaaga cgaagaggaa ggccttcagt ctgatggggc
     2341 tgatgatgcc tttgccttgt ggctgcagga ctcaactcag actctgcagt gcatcacaga
     2401 gctgttcagc catttccagc ggtgtacagc cagtgaagaa actgaccatt ctgatctcct
     2461 gggcaccctc cacaatcttt acttgattac ttttaaccct gtgggaagat cagctgttgg
     2521 ccatgttttc agccttgaca aaaaccttca aagtctcatt actctaatgg agtactattc
     2581 caaagaagcc ctaggcgatt ccaagtctaa gaagtcagta gcttataatt acgcatgcgt
     2641 actcacgctg gtggtggctc agtcttccag cggtgtccag atgttagaac agcacgcagc
     2701 atcgctcttg aagctctgca aagcagatga aaataatgcg aaattgcaag aacttggcaa
     2761 atggcttgaa cctctgaaaa acctcagatt tgaaattaac tgcatcccaa atctaattga
     2821 atatgttaaa cagaatattg ataacttgat gactgcagaa ggagttggcc ttaccactgc
     2881 cttacgtgtt ctctgtaatg tggcatgtcc accacctccc gtagaaggtc agcagaaaga
     2941 cctgaaatgg aaccttgctg ttattcagct tttttctgct gaaggaatgg acacctttat
     3001 tcgggttctg caaaaactga acagtatttt gacgcagcct tggaggctcc atgtgaacat
     3061 ggggactacc ctgcacagag tcactaccat ttcaatggct cgctgcacgc tcactctgct
     3121 taaaactatg ctgacagagc tcctgcgagg cggatccttt gagtttaagg acatgcgtgt
     3181 tccttcagca cttgttactt tacacatgct cctgtgctct atccctctct caggtcgttt
     3241 ggatagtgat gagcagaaaa ttcagaatga tatcatagat atcttactga cttttacaca
     3301 aggagtcaat gagaagctca cgatctcgga agagactctg gccaataata cttggtcttt
     3361 aatgttaaag gaagttctct cttccatctt gaaggttccg gaaggcttct tctcaggact
     3421 catactcctt tcagagctgc tgcctcttcc cttgcccatg cagaccacgc aggttattga
     3481 gccacatgat atatcagtgg cactcaacac ccgaaaattg tggagcatgc accttcatgt
     3541 tcaagcaaag ttgctccaag aaatagttcg ttctttctct ggcacaacct gccagcccat
     3601 tcaacatatg ttacggcgta tttgtgttca attgtgtgac cttgcctctc caactgctct
     3661 tctgatcatg agaactgtgt tggatttgat tgtagaagac ttgcaaagca cttcagaaga
     3721 taaagaaaaa cagtatacta gccaaaccac caggttgctt gctcttctcg atgccctggc
     3781 ttcacacaaa gcttgtaaat tagctatttt gcatctaatt aatggaacta ttaaaggcga
     3841 tgaaagatat gcagagatct tccaggatct tttagctttg gtgcgctctc ctggggacag
     3901 tgttactcgc cagcagtgcg tggagtatgt cacatccatt ttgcagtctc tctgtgacca
     3961 ggacattgca ctcattttgc caagcccttc tgaaggtcct gcctctgagc ttgaacagct
     4021 ctctaactcc ctaccaagta aagagctgat gactgcaatc tgcgactgtc tgctggcaac
     4081 tctagccaac tctgaaagca gttacaactg tctgctgaca tgtgtccgta caatgatgtt
     4141 tcttgcagag cacgattatg gattgtttca cctgaaaagc tctttaagga agaacagtag
     4201 tgctctgcat agtttgctga agcgagtggt cagcacattc agtaaggaca ccggtgagct
     4261 tgcatcggcg tctctggact tcatgagaca gatcctcaat gctgatgcta tgggctgttg
     4321 tggagacgat agtggtctca tggaggtaga gggcgctcac ccaccccgga cgatgagtct
     4381 taacgctgca gagttaaaac agctcctaca gagcaaagaa gagagtccag agagtctgtt
     4441 ccttgaacta gagaagcttg ttttggaaca ttctaaagat gatgacagtc tggagtcttt
     4501 gctggataat gtaattggac tgaagcagat gctggagtca tctggtgagc ctttgcctct
     4561 cagtgaccaa gatgtagagc cagtactgtc agctccagag tctctccaga atttatttaa
     4621 caacaggact gcatatgtgt tggctgatgt catggatgat cagttgaaat ctatgtggtt
     4681 tactccattt caggctgaag agatcgatac agacttggat ttggtaaagg ttgacttaat
     4741 tgagctttca gaaaagtgct gcagtgattt tgatttgcat tcagaactag agcgctcgtt
     4801 tctgtcagaa ccatcatctc caggaagatc caagactact aagggattta aactcgggaa
     4861 gcataagcat gagacattca taacttcaag tggaaaatct gaatacattg aacctgccaa
     4921 acgagctcat gttgtgccgc cacctagagg ccggggccgg ggaggatttg gacagggcat
     4981 acggccccat gatattttcc gtcagagaaa gcagaacacg agcaggccgc catctatgca
     5041 cgtggatgac tttgttgcag ctgaaagtaa agaagtggtc cctcaagatg gaataccccc
     5101 accaaaacgg ccactcaaag tctcacaaaa gatttcctct cgtggtggat tttcaggcaa
     5161 ccgaggagga cggggtgctt ttcatagtca gaacaggttt ttcacaccgc ctgcttcgaa
     5221 aggaaactac agtcgtcggg aaggaacaag aggctcgagt tggagtgctc agaacactcc
     5281 tcgaggaaat tataatgaaa gccgaggggg ccagagcaac tttaacaggg gtcctcttcc
     5341 accattacgg ccgcttagtt ctacgggtta ccgccctagt ccccgggatc gagcttctag
     5401 aggccgcggg ggcctgggac cgtcctgggc tagtacaaat agcggcagtg gaggctcgag
     5461 aggaaagttt gttagtggag gcagtggtag aggccgtcat gtacggtcct ttactcgata
     5521 gatgtgttct tggcaacacc ccaagtaaat gcacatttca tgaggacaaa aacaaacaga
     5581 ccttgaagga ccaatttaga cttaacagtt atatctggat acatctgaga gaatattttt
     5641 atctgaagaa agcagatttt gtttgatact taatgagatt tcaataaaaa tccaaacttt
     5701 gtacgtatgt ttgtatatat ttttcccatt ttatatggta tttatttaga aagtttctag
     5761 gtagaaagaa aaaaacaatg attttttttt tttgtatttc tcttgcttat actatagata
     5821 tttccaaact ttcttagcct gtgacaccct ttagtgtgtc tcgggaattt tttcacagta
     5881 tccctaggcc aaaaacaaac ttgatacttt tgtttattga acagttaggg tccaagcaac
     5941 tgaagacttt ccaccatcat caccactagt aactggacac cgctcaaggc ctcactcacc
     6001 cttggaaaca gcagccttcc ctgtccgggt ttcctgagca gtactgttta tcaaactgct
     6061 gaatggtcgt tacaaatgtg tgctgtcctg gaaagtcacc cagtgttacc cagtgctgaa
     6121 aatgggaact acctcaattc atagtttgtg tggtgcccag cagatgtcgc tgtttcctca
     6181 gaagtttaaa acactcatgc taatttacta aggtgcccac cacacaattt agcaatcatt
     6241 gctgtaccag aaggagcaaa aacttcttta tgttagaagt acagactttg cttcaagttc
     6301 ggacctactg atgctatttt attatagagt tatttaaagc ctaaaagttg gcttatctta
     6361 atgcggttat tttgggaatc agaagcatct actttatatt cagaaataaa acttataact
     6421 ttgaccaagg agccatattt cccctaaggt atgtcttaat tcattgagcc tatataaatg
     6481 gcataaaata tagagttctc ttaaacaaaa ataagtgtat gagtctcatt ccatcctaac
     6541 agcctctatt ttggggaatc acttgagtgc atttaatata tatttattag gaaaaaaggc
     6601 ctcgaaaagt tcagctttag aattgagggt ttagcttatt gatagaagta gttgcctagc
     6661 atgtgtgatt aactactagc aatgtttctg agtgtgtgtg tgtgagcatg cacatgtgta
     6721 cacatacatg tgcatggaaa tttcagatgg aaggattctg atgtttaagt acaaggtgat
     6781 gaaaatcttc ttactattct ggaacaaccc aaactcttag tctgctcagg ctgctataac
     6841 atcataaaat agactggatg gcttatataa gaagaaaatc tcacagttcc attggtcagg
     6901 cagtcggtaa aagcaggctc tggggaggca ctccttgtag acttttcaca tgggctttct
     6961 gtagt
//
