LOCUS       NM_172538              11124 bp    mRNA    linear   ROD 31-JUL-2024
DEFINITION  Mus musculus vezatin, adherens junctions transmembrane protein
            (Vezt), transcript variant 1, mRNA.
ACCESSION   NM_172538
VERSION     NM_172538.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 11124)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 11124)
  AUTHORS   Wang,Y., Yuan,J., Yu,X., Liu,X., Tan,C., Chen,Y. and Xu,T.
  TITLE     Vezatin regulates seizures by controlling AMPAR-mediated synaptic
            activity
  JOURNAL   Cell Death Dis 12 (10), 936 (2021)
   PUBMED   34642320
  REMARK    GeneRIF: Vezatin regulates seizures by controlling AMPAR-mediated
            synaptic activity.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 11124)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 11124)
  AUTHORS   Koppel,N., Friese,M.B., Cardasis,H.L., Neubert,T.A. and Burden,S.J.
  TITLE     Vezatin is required for the maturation of the neuromuscular synapse
  JOURNAL   Mol Biol Cell 30 (20), 2571-2583 (2019)
   PUBMED   31411944
REFERENCE   5  (bases 1 to 11124)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643. PMID: 29144450]
REFERENCE   6  (bases 1 to 11124)
  AUTHORS   Hyenne,V., Souilhol,C., Cohen-Tannoudji,M., Cereghini,S., Petit,C.,
            Langa,F., Maro,B. and Simmler,M.C.
  TITLE     Conditional knock-out reveals that zygotic vezatin-null mouse
            embryos die at implantation
  JOURNAL   Mech Dev 124 (6), 449-462 (2007)
   PUBMED   17452094
  REMARK    GeneRIF: These in vitro observations reinforce the idea that
            homozygous vezatin-null mutants die at the time of implantation
            because of a defect in intercellular adhesion.
REFERENCE   7  (bases 1 to 11124)
  AUTHORS   Hyenne,V., Harf,J.C., Latz,M., Maro,B., Wolfrum,U. and Simmler,M.C.
  TITLE     Vezatin, a ubiquitous protein of adherens cell-cell junctions, is
            exclusively expressed in germ cells in mouse testis
  JOURNAL   Reproduction 133 (3), 563-574 (2007)
   PUBMED   17379651
REFERENCE   8  (bases 1 to 11124)
  AUTHORS   Hyenne,V., Louvet-Vallee,S., El-Amraoui,A., Petit,C., Maro,B. and
            Simmler,M.C.
  TITLE     Vezatin, a protein associated to adherens junctions, is required
            for mouse blastocyst morphogenesis
  JOURNAL   Dev Biol 287 (1), 180-191 (2005)
   PUBMED   16199027
  REMARK    GeneRIF: Required for morphogenesis of the preimplantation mouse
            embryo.
REFERENCE   9  (bases 1 to 11124)
  AUTHORS   VanBuren,V., Piao,Y., Dudekula,D.B., Qian,Y., Carter,M.G.,
            Martin,P.R., Stagg,C.A., Bassey,U.C., Aiba,K., Hamatani,T.,
            Kargul,G.J., Luo,A.G., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Assembly, verification, and initial annotation of the NIA mouse
            7.4K cDNA clone set
  JOURNAL   Genome Res 12 (12), 1999-2003 (2002)
   PUBMED   12466305
REFERENCE   10 (bases 1 to 11124)
  AUTHORS   Kussel-Andermann,P., El-Amraoui,A., Safieddine,S., Nouaille,S.,
            Perfettini,I., Lecuit,M., Cossart,P., Wolfrum,U. and Petit,C.
  TITLE     Vezatin, a novel transmembrane protein, bridges myosin VIIA to the
            cadherin-catenins complex
  JOURNAL   EMBO J 19 (22), 6020-6029 (2000)
   PUBMED   11080149
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AK031848.1, BC056428.1,
            AK036017.1, AC122901.4, AK048068.1, AK031192.1, AK042209.1 and
            AW124866.1.
            
            On Feb 5, 2015 this sequence version replaced NM_172538.4.
            
            Summary: This gene encodes a transmembrane protein that is
            essential for the formation of adherens junctions. It is required
            for both the pre-implantation morphogenesis of a blastocyst and for
            the implantation process. The encoded protein is also a component
            of the ankle-link complex in cochlear hair cells, where it may
            effect resilience to sound trauma. It is also thought to be
            involved in dendritic spine morphogenesis. Alternative splicing
            results in multiple transcript variants. [provided by RefSeq, Feb
            2015].
            
            Transcript Variant: This variant (1) encodes isoform 1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK036017.1, BC056428.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-63                AK031848.1         3-65
            64-2944             BC056428.1         1-2881
            2945-3282           AK036017.1         2895-3232
            3283-3283           AC122901.4         91057-91057         c
            3284-4530           AK036017.1         3234-4480
            4531-5883           AK048068.1         334-1686
            5884-7695           AC122901.4         86645-88456         c
            7696-9718           AK031192.1         2-2024
            9719-9790           AK042209.1         870-941
            9791-11107          AK042209.1         943-2259
            11108-11124         AW124866.1         1-17                c
FEATURES             Location/Qualifiers
     source          1..11124
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10"
     gene            1..11124
                     /gene="Vezt"
                     /gene_synonym="A630071D13Rik"
                     /note="vezatin, adherens junctions transmembrane protein"
                     /db_xref="GeneID:215008"
                     /db_xref="MGI:MGI:2143698"
     exon            1..130
                     /gene="Vezt"
                     /gene_synonym="A630071D13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            131..265
                     /gene="Vezt"
                     /gene_synonym="A630071D13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            266..355
                     /gene="Vezt"
                     /gene_synonym="A630071D13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            356..528
                     /gene="Vezt"
                     /gene_synonym="A630071D13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            529..804
                     /gene="Vezt"
                     /gene_synonym="A630071D13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            805..942
                     /gene="Vezt"
                     /gene_synonym="A630071D13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            943..1090
                     /gene="Vezt"
                     /gene_synonym="A630071D13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1091..1422
                     /gene="Vezt"
                     /gene_synonym="A630071D13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1423..1616
                     /gene="Vezt"
                     /gene_synonym="A630071D13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1617..1717
                     /gene="Vezt"
                     /gene_synonym="A630071D13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1718..1925
                     /gene="Vezt"
                     /gene_synonym="A630071D13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1926..11108
                     /gene="Vezt"
                     /gene_synonym="A630071D13Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2433..2438
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Vezt"
                     /gene_synonym="A630071D13Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2454
                     /gene="Vezt"
                     /gene_synonym="A630071D13Rik"
                     /note="major polyA site"
     regulatory      2921..2926
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Vezt"
                     /gene_synonym="A630071D13Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2944
                     /gene="Vezt"
                     /gene_synonym="A630071D13Rik"
                     /note="major polyA site"
     polyA_site      5879
                     /gene="Vezt"
                     /gene_synonym="A630071D13Rik"
     regulatory      11086..11091
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Vezt"
                     /gene_synonym="A630071D13Rik"
                     /note="hexamer: AATAAA"
     polyA_site      11108
                     /gene="Vezt"
                     /gene_synonym="A630071D13Rik"
ORIGIN      
        1 gcccccgagg tgggcaggag ccgaagcctg ggtgctgccc gccctcctgc cttcatttcc
       61 catcgtgctg aggcgggtgg tatggcggag aaggatgaca ccggagtttg acgaagaggt
      121 ggtttttgag aattctccac tttaccagta cctacaggat ttgggacaca cagattttga
      181 gatatgttct tcttcgtcac caaaaccaga aaaatgcttg acaacagagg gacctcagcc
      241 gcctcccacc agagtcctac agagacaagg catcctgttg aaactgacag aaaccatcaa
      301 gagctggacg ttttcctctc agcacagtaa gaaagatgac ttactccata agttggacac
      361 cgggtttcgg ctggactcac tgcataccat cctgcagcag gaagtcctgc tgcaagagga
      421 tgtggagctg ctcgagctgc ttgacgccag catcctgtct gcggggcagc ctcaacagga
      481 aagtggacac cttccaacgc tctgctccct ggcaaccccg aacacttggg atgtctcgct
      541 gctgtttgcc ttcattagtt tgctcatcat gtttcccacg tgctggattg tgtcctcctg
      601 gctggtgtgg ggaataattc tatttcttta cttgatcata cgagttttga aattatggag
      661 gacagccaaa ctgcaaatga ctctgaaaaa atatagggta cgtttggaag acatggcagc
      721 caatagccga gccttcacca accttgtgag aaaatcactg cgtctcatcc aagaaactga
      781 agtcatttcc aggggattta ctctggtcag tgctgcttgc tcatttaata aggctgcaca
      841 gcatcccggc cagcatctca tcggccttcg gaaagccgtc tacaggaccg taagagccaa
      901 ctttcaagcc gcaaggctag ctaccttgta catgctgaaa aactaccccc tgaactctga
      961 gagtgacaat gtcaccaact acatctgtgt ggtacctttt aaggagctgg ggcttggact
     1021 cagtgaagac cagatctcag aagaggaagc tcgtaacctg acagatggct tcagcctgcc
     1081 tgccttgaag gttttgttcc agctctgggt ggcacagagt tcagagttct tcagacgcct
     1141 ggccctgtta ctttctacag cgaattcgcc ttcagggccc ttactcactg ctgcacttct
     1201 gcctcatcat atcctctgtg acgtgactca aggtctacct catgctcact ctgcctgctt
     1261 ggatgagctg aagcgcagct atgagttctt ccggtacttt gaaactcagc accagtcagt
     1321 cccccagcgc ttatccaaga ctccgcagaa gtcgagggag ctgagcaacg tccacacagc
     1381 agtccgtagc ttacagctcc atctgaaagc actactgaat gaagtaataa ttcttgaaga
     1441 tgaacttgaa aagctcgttt gtactaaaga aacacaagag ctgctatcgg aggcttatcc
     1501 gatactagag cagaaattaa aactgattga accacacgtt caggccagca acagttgctg
     1561 ggaggaagcc atttctcaag tggataaact gctccggagg aacacagata aaaaaggcaa
     1621 gcctggagta gcctgtgaga acccacactg caccgcggag cccttggtgc ggccagctct
     1681 acacattgag gacagagacc ccatccctga ggagcaggaa ttagaagctt atgtggatga
     1741 catagacata gaaagtgagt tccgaaagga cgatttctat cacttgtctc aggaagacag
     1801 agagagacag aagcgcgagc aggaggagtc caggcgggtg ctgcaggagc tgaagtctgt
     1861 gctgggattt aaggcttccg aggctgagag gcagaagtgg aagcagctgc tgttcagtga
     1921 ccacgctgtg ttgacatcct tgtctcctgt agacccagtg gaatctgtaa gtaactcaga
     1981 accacccatg aattcagata cagaaaaagt caatagtaat gctactgaag aggagactag
     2041 taagccctgt gccggcgaca aggaagacag taggactgag tatgtgtgtg acagcccaac
     2101 agaggggcca agcaaagaca cctctgcaga cacaggcctc ctccttccag gagccgagga
     2161 aaccatgtgc caccagcatg agagtgaggc taagtctcct caggctgctg ctgcgggggc
     2221 cactgcccct ccgactccca gggacacact gcaactctcc attaagcaga ggctggctcg
     2281 actccagttg ccaccagaat tcaccttctc tgctggcctg gctgcagaag tggccgcccg
     2341 gtccctgtcc tttaccacca tgcaggaaca aacttttggc gacgaggagg aagaacagct
     2401 agttgaaggc ggtgaaaatg aggtggagga aaaataaaag ccaagatgaa gcgatggcct
     2461 tgattgttct ttttacaaaa gtgttctagc tgcaagactg gaaagagaaa tgagtgtgtg
     2521 tttactctct ataaggctac ggcgtgaatt tacagggtga atactgattt gaaaacctga
     2581 cctgaaacta gtagatacct gtctagtcag atcctttagg cataggagag aaaggtaagg
     2641 gactttttta aaaaataaat aaataaactg ctgttttatt tgtggcaaaa ctgataatct
     2701 tggcaaatct ttaagtactt ttaataagac atgaatttat cactttttgc caaaactttg
     2761 ctgccacaag gtaactaggg tgattgtctt cccgagcaga aacatttaga atgagccctt
     2821 tctactgtgt ccttgcagtg tgaactgcag cggtcatgtt aatacattgt tcgtacttta
     2881 ttttgtttat accactcgta aaacaaagag acaggttcta aataaaagta tttaattacc
     2941 acaaccgatg tgtgctgggg tttggaactg gaaagtagtt agcagggagc tgggactgca
     3001 gcgtatcttg gacatttctc acgggtcatg cagaggttaa gaggacaatg tcctcttagg
     3061 ggacacccca tgatgtccaa gcgctgtcac tccagcaaag gccccagccc cagccctgca
     3121 ggaactaatt tacatcagtt tactggaaga caactgtgcc tctgcagtag gtaggtcctg
     3181 tgctgtcttc tagcctggcc tgccttacta agactcagga aacgcgtcag ctatcttgga
     3241 aagcatcctt gtccctttgt gcttcatcgt gaatgcgtct cgagatgctt tccagagacc
     3301 agtcttgtcc gctttgtgct ggaattgtgt tttcaatgaa atttgcagaa acagtctcct
     3361 tctgaaacct gttgccactg tgcgctccca gactttatag gcattcttct gtgaggaatg
     3421 taagaaagaa aaacaaacaa aaacaaaaca acaaaactca gttgatgctg ctgtttcagg
     3481 aggaaagtat ctgacttcct gtaacttact gcttttagca ggaagcttac ttcttctcaa
     3541 ggtttgttgt tgtttttgga actgtttctt ctcctgagga aaatctttcc ctttgtctac
     3601 actgttggtg atgttgcctt tgctgatact tagcagtgca gcatggccag agccgtcagt
     3661 cccttaagtc agacatggaa gatgcttaac ttcaagagaa aaggaagttt ttttagggaa
     3721 attttgttaa gcgttctctt aatttttaac acaggaaaac ttagtcattt ttaattcttt
     3781 tagtctattt tgattcaacc atagcaattt catagaaacc cattcataat cttatttgcc
     3841 agtttttata gcatgattca tctttttggg agtagtattc tgacagcttt tactacagat
     3901 actgccaaca ttggttttac caggatcaat ctagaactca gaagaaaaaa aaagcgtgct
     3961 ttttgttttg gggtcactca tgaaaacaga atttttaccc ttggtgcatc tgcagatggg
     4021 caggtcggga cagtaagtgg tctgtggtca cctagcagat gggcaggtcg ggacagtaag
     4081 tggtctgtgg tcacctagca agcctcaaaa ctttttctct gtttctgtaa ggccctgatg
     4141 tctgtcagat gcagggccag agtcctggct aatctttcat ttgcagtcct ctgtgatttt
     4201 tttttttttt ggtttttttg ggttttttgg ttttttgtgc aagctatgca tattatctaa
     4261 cttcataaag cccttgttgt ccttcttaaa actaattaat agtcacagca tctgaaccta
     4321 ttaggagttg atgataagtg agttaggaag agaacacaca tttaaggcag attgctaagg
     4381 atgtttaaga atacagattt cagaccgtga cgcgacttgt actggtgatg ccagcacccc
     4441 aggtgcactg ttaggaaggc tactgcgagt ccgaggccag ttgagcgtgc tccaggatag
     4501 ccagaaatac actgtgcgaa cctgtccagg aagaaaagaa aaaagaaaga aaagaaaaca
     4561 acaggtgcca ggtgtctgca aaaagaggcg ggagtttgaa tcccaggcct tttgttcaga
     4621 ggattcaagt actgtgacct tatcatctag ggagagtctt ctcaggaaaa ctgtaattcc
     4681 tggaaatgca gaaagaaatg ttggtttgga ggctggagaa gttataaatg tatagctcca
     4741 tttattaaag tagatagtaa tatcctactt tatatactaa aagacagttg cttgaatggt
     4801 aagcataaga aaagtcaatt tctgatccat ttaaaagact agaacttggc tgggtgttga
     4861 tagaattgac ctcaggttgt gtcactcaga tattttcttc ccatgcaaaa catgaatcat
     4921 gcttcaagtt gctaaatgaa tagaaacact agggggaggg ctgttatcag ttagccatag
     4981 catattgctt ttatactcaa atagagcaag gataccagaa ccaagtcctg aagccaaaag
     5041 tgagtttttt ccagatctgt gtatggggac ttatttgtac tttatgctta aattagaaaa
     5101 aaagattcaa aaagaaaaat gtaggaaata aaagacagca aaatgtccag tatagtgacc
     5161 gttcattgtc ttcgtcagct ggtgactaac ttgagtcccc tcatctctca gggaacaaaa
     5221 gcaagcccat gtatttagtc cttggactta acagtctgct tacaggatca cgtctccttt
     5281 tctcccttaa ctctggcacg taccggaact agcttagcct gtcctttggg aaccggaact
     5341 agcttagcct gtcctttggg aaccggaact agcttagcct gtcctttggg gacatcagtt
     5401 cctttgggga agaatgcaca cgtcccctct cggggacaac tgggattgat aacgtcaggc
     5461 actcctttgc tgcgagattt cacattgctt gctttttgag tcgtgtctgt ttttttcaca
     5521 gtttctctta ccttccccta taatccgccg tgttgtgtgc ctgccttccg cactaggccc
     5581 ctaatttgct gcttttaatc tgctgtggac tgagaaaccc gattgccacg cttgctagaa
     5641 ctgtgtctaa actaagagta agtagactgg aaaaggccga gagcttttct gtcggtcgtg
     5701 tgcatgaacc ttgtattgcc tggtttgctg cttagcattc ttgtgtgtgc atttagtgtt
     5761 ttactaagaa gtggctaaga cattacttgg ttaaaaatgt gattgccgtg tatttgaaat
     5821 attaatttgg tgtttgtatg ctgatgtgct aggtctcttt atcaatgaat gtaactgtag
     5881 aagaaaaacc gactctcccc tttgtatgtc actgtgtgtg tttcagaaga atgttggcca
     5941 tttgttttgg ttaattagtt ttcactcagt acacaggctt aaagtttatg tcattattcc
     6001 gaattctgca tagcatgtct tattaccaag agttactggt ttgaaactaa acctgactca
     6061 tttagtaaga actggcagac ttgacagggg aataaatgat ttggacagcc cagttctcta
     6121 gcaatgtatg aaatacacca taatctttgc tatattacaa cggttatcaa ggagctgggg
     6181 agatgactca ctgggtaaag tgtcctctaa acaagtacga gaatgagaac cttcactcag
     6241 atcccagtgc ccatataaaa gagctgggca tatatatggc atacatctat aaccccatgc
     6301 ctggggttag agtcagaaaa atccccagaa agtctctggc cagccactct ggcctcatca
     6361 gtgagagtgg tctagggaaa ccctaaacat caactcaacc tctgacttag cccatataca
     6421 cacatgtaca tacacatgaa tatgtgtgtg cataccctct tgtatacatg tacacaaaga
     6481 cacaaattca tcatcataat catcatagcc attggttttt tgagacaggg ctgctctata
     6541 ttgcctaccc tggaactcat tatgtagaca aggctgaccc tgagatttgc ctgtctctgc
     6601 ctgccaagtg ctaggatgaa agacatggac tactacagcc agctcaaaat ggtcattatt
     6661 aacacgggtt gttatcctct ggtacactaa acgccaagaa ctgtcccttt attaagttcc
     6721 atttgacttg actgggcttc agtcatcatg cgttcagttt tggtagggat tcctccgttc
     6781 ctgttactgc agattaagtg tgcgtgaatt agcggccctt gtccgctctc acgcatgcct
     6841 tccgacctgc tgtgaagact agatgactct gctagttaag ctgtgtaagg taagagcagg
     6901 cagatgcaga gtgacaggca tactgctgac gctcactgac tcttctgaag gatttcttat
     6961 gacgtgctgg attacagtct ttgacccagt gaaattgctg ggttaaatgc ctactttcaa
     7021 tatgaaagta ttgttataca agataatttt ccccaacatc ttgccttctc taaagttggt
     7081 tctatacctg taactctttt gcagtgatta ctgtcatata tactttccat ttgaattgga
     7141 aaccacatgc tgtcctgaat ttctttggct ctcttattta agataaatgc gtcttcattt
     7201 ccaagacaaa gtagattaag ccatggaaaa taagaaaaca attattgaag atatctgaga
     7261 agtactacaa ttgtagaacc taggccacaa agaataacat gattatgaaa gaccatccac
     7321 gctgacagca tctttgcttt ctttaattca gctaaaggaa gtgaagtata cattaaaagt
     7381 ttcccatgat tcatcagtgt taactcagtg gcagaagatc cactgtcatt cagtagttgg
     7441 catgcctaaa ttagccttca gtgtataaaa taagcaagat tacattttcc aataatacta
     7501 gactgtctag aagtggctct cctaacatct gcttagttgt accgtttatg tgctgtgctt
     7561 tgctaaccat gggactcgct gtcatcatat acagagtgag tagtgtgtca gtctatttta
     7621 ttctcatgct tcatggaact cactctcatt acattcagcg tggatgctgt atcagacttt
     7681 cataatcatg cttcatgtgg ctgctctcca gttacccatg ttatggaagg gaattatgat
     7741 ataataattg taagaagaat ggtccaaacc agttccttgt attgacacca ttgtagaaga
     7801 gacagtgatg gcagacatga ttggtgcttc tctctgagta agctgttaga gaagcacaat
     7861 tctacccagt gcaattgctg taaaccaaaa agaaggagtt cataccgggg tttacatagg
     7921 caagattcag caggaattag gaggaattaa tttcatacct atctttaaat gtgtgatcaa
     7981 atctaggtgt agtggcacat acctttaatc cctgcactct ggaaacaggc aggcatatct
     8041 ctgatttcaa ggccagcctg gtccacatag tgagttcctg actggccaag gtttatatat
     8101 atagtgatga ttgtgtgata gattctaatg cccatggtgt ctttaaaatg cagtccatta
     8161 gaatccactt tagtgtgtca gcagtgacat tagttttatc cctgtgtact gagattcact
     8221 tagcacatat gttgctcaag tggaaatgat gcttagggtg tgtatacttc tgattataca
     8281 agctgaaaaa ttggactacc tgtagataat gctaaataga tattttttct cacttatttc
     8341 ttaagagttt cttaaaatag atagtattat tttaggattt ataacagttt tataacatgt
     8401 cctaaagact gactacatac aaataagttt attgttgcaa atctcttcta aaactaaagt
     8461 atgtcctttg taagtttgct cttttacaat gacctaaaca acttcttagc ccgcttttcc
     8521 ttccaagtta aatgactaaa ttgactctga ttctgagtcc aagtatgttc tgcatttttc
     8581 tgtaccttct gttcaagtct gtgacttaaa agtgctgagg cacagtactg gtgtgtgaca
     8641 atatatagaa ggctccaaga atgtcactcc tatcccttaa aggttggtgt gtggccctga
     8701 tccagccctg gaggcccaca tgggtgagaa gcccagaagc ccatgcaagc tgaaagcact
     8761 cccaaggagt ctggttttgt ttgggtttgt tctaggtatg gtcccaggga tcccagatca
     8821 aaccaggccc ctgggcctat cctagaacca acctaaaccc gtgcatcatt cctggaacac
     8881 ccagaggatg aagaccgaag ataactgagg ctgactacac atcctgtact caccaagatt
     8941 cagttcttat atatgtacct attgtttagc aagccctggc tggttaatct gtctggagtc
     9001 aaaataacaa tatttggtaa taacaaagtc tcccgaggct gataccccag tagtttccta
     9061 tggtagaaat tctatgtggt tgttattaat tcccagtgag gagaactggt cttgtgattt
     9121 ttatcgtcag ataaaactga tttaaatgtc tattttaaaa agcagcaatg tagccacaaa
     9181 accgttctca aaacagcctt cttccaaact ggacaaattg tcttttctta actacttcca
     9241 gtgatgtcta accagtctct gtcagctgta tgctttattg gcactttcgg aacggcaagc
     9301 atctgtcttc gtcttcccac tctaatgctg agtggctcta agttcttgtt tcagaaatta
     9361 gtatgttttc cctgtcactg ggtctgctgc gcagcagagc tccttttaag gtttctgtgg
     9421 ctcaggacca tgagtatggt gaggtagtag atggttaagc ccgtggattt tgcagcagta
     9481 ttgtgcagaa gaaaatttta agaacttcag ttttcttcct gatctaataa atatatgtta
     9541 tgacctcata atctagctgg cattactaga gtcaactgtg tgtttatttg ttttgatttg
     9601 gaagacaaga attctgaaaa tgcatgaaga cccaaactga aaaattatgg taagcattga
     9661 caatttatgc ttttgatgtt ttgtgcagac taataaactc tccatacata aggaactcaa
     9721 aatcatgcat tcctaccaat ctttatcaca ctaccaaaat ttacgtcacc cagtcacagt
     9781 tccaaatggg cctggcgcct attgaggctc acccgaaaaa ctcaactatt ctacaccata
     9841 ttcatcccat ttctacccca agtttatggg aatttttttt atgccacaga ttgagttttg
     9901 tgcttctcag tgttttcttc cttggagtgt gtgcctcatg aacacactta cctaagagat
     9961 cagcattgcc tagaatccat gtgcacacac caggttgatg tgtaatatgt tttgtgagta
    10021 ttttgggggc attatactca tttacatcat aaatagagac caaaaataga aattatggac
    10081 tgtttaatta ggtttgtttt tttgagtcag gacctcatac cctaggttgg ctttgaactt
    10141 gctgtatagc taaggttggc cttgaacttc tgaccttcct gcttttacct cccaggttct
    10201 gttactgtaa gtgtgtacca cagacctggc tctgtatttt tgttggtggt ggtggttttt
    10261 gtttttggtt tcgaggcatt atgtaactaa caatgaccgg cctggaactt gctgatcttg
    10321 agcttctgac aatcctcctg cctccacctc tagagagctg agattacaga catgcgccac
    10381 cattcttggc aaggtttggc tcttgagtaa ggttttaaag tatactcagt ggtaaagcac
    10441 tggctatgag gtctagctct gagaccctcc acctccaaag ggccttggga tggttactaa
    10501 tctttatata ctagaacttt gaactctcaa ttccctaccc taactgaaga cttatggtta
    10561 taaaatctgg gccggagggt gcttttttgt ttaattgcga taaagcatca aaattttcac
    10621 cattgccacc atttttatgt tcaattcagg aaatgcctgt gcctttaatg aagcgtttgc
    10681 agaactttca attgtgcagg tcttaaaatc ttctatgatt aagataagag ttctccttcc
    10741 tccctctcct ttcccacagc ccctggcagg caccattctg tctcctgtta tgaccgcaag
    10801 ttcatctcat ttagcatgtg acagaatttc cttttttagg gctgaataat ctgcacattt
    10861 gctagatctt gtggatcatt catcgactgg cgggcattga ctgcttccct ctcttggtta
    10921 ttataaagga tattgctatg gatatgagca ggtatctcct ttttaacgtg gtaccttatt
    10981 aatcactttg ctgtatcgca ttaccttggc aactatttta aagcgttaga attgtaggct
    11041 tgcttatgct gtataaactg ttcctcctaa gcttaaagga tctctaataa aatctcagat
    11101 tccctgtaaa aaaaaaaaaa aaaa
//
