LOCUS       NM_011692               1601 bp    mRNA    linear   ROD 24-DEC-2024
DEFINITION  Mus musculus von Hippel-Lindau binding protein 1 (Vbp1), mRNA.
ACCESSION   NM_011692
VERSION     NM_011692.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1601)
  AUTHORS   Cox,B.J., Vollmer,M., Tamplin,O., Lu,M., Biechele,S.,
            Gertsenstein,M., van Campenhout,C., Floss,T., Kuhn,R., Wurst,W.,
            Lickert,H. and Rossant,J.
  TITLE     Phenotypic annotation of the mouse X chromosome
  JOURNAL   Genome Res 20 (8), 1154-1164 (2010)
   PUBMED   20548051
REFERENCE   2  (bases 1 to 1601)
  AUTHORS   Xiao,C., Sharp,J.A., Kawahara,M., Davalos,A.R.,
            Difilippantonio,M.J., Hu,Y., Li,W., Cao,L., Buetow,K., Ried,T.,
            Chadwick,B.P., Deng,C.X. and Panning,B.
  TITLE     The XIST noncoding RNA functions independently of BRCA1 in X
            inactivation
  JOURNAL   Cell 128 (5), 977-989 (2007)
   PUBMED   17350580
REFERENCE   3  (bases 1 to 1601)
  AUTHORS   Nelson,P.S., Pritchard,C., Abbott,D. and Clegg,N.
  TITLE     The human (PEDB) and mouse (mPEDB) Prostate Expression Databases
  JOURNAL   Nucleic Acids Res 30 (1), 218-220 (2002)
   PUBMED   11752298
REFERENCE   4  (bases 1 to 1601)
  AUTHORS   Hemberger,M., Himmelbauer,H., Neumann,H.P., Plate,K.H.,
            Schwarzkopf,G. and Fundele,R.
  TITLE     Expression of the von Hippel-Lindau-binding protein-1 (Vbp1) in
            fetal and adult mouse tissues
  JOURNAL   Hum Mol Genet 8 (2), 229-236 (1999)
   PUBMED   9931330
REFERENCE   5  (bases 1 to 1601)
  AUTHORS   Brinke,A., Green,P.M. and Giannelli,F.
  TITLE     Characterization of the gene (VBP1) and transcript for the von
            Hippel-Lindau binding protein and isolation of the highly conserved
            murine homologue
  JOURNAL   Genomics 45 (1), 105-112 (1997)
   PUBMED   9339366
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DV066998.1, BY134471.1, AK077923.1 and BY476349.1.
            
            On Jan 27, 2007 this sequence version replaced NM_011692.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK077923.1, AK008847.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-9                 DV066998.1         36-44
            10-16               BY134471.1         3-9
            17-1590             AK077923.1         2-1575
            1591-1601           BY476349.1         539-549
FEATURES             Location/Qualifiers
     source          1..1601
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 38.25 cM"
     gene            1..1601
                     /gene="Vbp1"
                     /gene_synonym="VBP-1"
                     /note="von Hippel-Lindau binding protein 1"
                     /db_xref="GeneID:22327"
                     /db_xref="MGI:MGI:1333804"
     exon            1..132
                     /gene="Vbp1"
                     /gene_synonym="VBP-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             43..633
                     /gene="Vbp1"
                     /gene_synonym="VBP-1"
                     /note="VHL-binding protein 1"
                     /codon_start=1
                     /product="prefoldin subunit 3"
                     /protein_id="NP_035822.2"
                     /db_xref="CCDS:CCDS41032.1"
                     /db_xref="GeneID:22327"
                     /db_xref="MGI:MGI:1333804"
                     /translation="MAAAKDGCGLETAAGNGRRLHLGIPEAVFVEDVDSFMKQPGNET
                     ADTVLKKLDEQYQKYKFMELNLAQKKRRLKGQIPEIKQTLEILKYMQKKKESTNSMET
                     RFLLADNLYCKASVPPTDKVCLWLGANVMLEYDIDEAQALLEKNLSTATKNLDSLEED
                     LDFLRDQFTTTEVNMARVYNWDVKRRNKDDSTKNKA"
     exon            133..257
                     /gene="Vbp1"
                     /gene_synonym="VBP-1"
                     /inference="alignment:Splign:2.1.0"
     exon            258..324
                     /gene="Vbp1"
                     /gene_synonym="VBP-1"
                     /inference="alignment:Splign:2.1.0"
     exon            325..423
                     /gene="Vbp1"
                     /gene_synonym="VBP-1"
                     /inference="alignment:Splign:2.1.0"
     exon            424..562
                     /gene="Vbp1"
                     /gene_synonym="VBP-1"
                     /inference="alignment:Splign:2.1.0"
     exon            563..1601
                     /gene="Vbp1"
                     /gene_synonym="VBP-1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1573..1578
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Vbp1"
                     /gene_synonym="VBP-1"
                     /note="hexamer: ATTAAA"
     polyA_site      1592
                     /gene="Vbp1"
                     /gene_synonym="VBP-1"
                     /note="major polyA site"
ORIGIN      
        1 gatgcctcag aaggtagtta tttgctctgg tgctttctga agatggcggc ggctaaggac
       61 ggatgcggcc tagaaactgc tgctggaaac gggcggcggc tccacttagg gattcctgaa
      121 gcagtgtttg tggaagatgt agattctttc atgaagcagc ctgggaatga gactgcagat
      181 acagtgttaa agaagctgga tgaacaatac cagaagtata agtttatgga actcaacctt
      241 gctcagaaaa aaaggaggct gaaaggtcag attcctgaaa ttaaacagac tttggaaatt
      301 ctgaaataca tgcagaagaa aaaagagtct accaattcaa tggagacgag attcttactg
      361 gccgataacc tgtactgcaa agcttcagtc cctcctactg ataaagtatg cctatggttg
      421 ggggctaatg taatgcttga atatgatatt gatgaagctc aggccttgtt ggaaaagaat
      481 ttatcaactg ccacaaagaa tcttgattct cttgaagaag accttgactt tcttcgagat
      541 cagtttacta ccacagaagt caatatggcc agggtttata attgggatgt aaaacgaaga
      601 aacaaagatg attctaccaa gaataaagca taacactggc aattgaaaat gtgattcagg
      661 ttttcaaaca tgttaaataa gccaaggttt aaagattgat ctaattttca ctgatttttt
      721 ttttcacagc aagattaaaa tttaaaaaca ccattttatt tatttatgaa aacaaaatta
      781 ctttcaaata ttttatgaaa ttaccagtat ttttttcata tttccctaaa atgtaatgct
      841 gcttttgttt tattttatct gttataagac aactcctaac tgaaatggcc gagaactgtg
      901 aggaatgcta tggaagctgc tgaatactgg gcaccagagc agttttcttt ttctttattg
      961 gttgatatta ctctcactgg atatggtaaa ccttttagag gcaggaaaga catacagttc
     1021 caatatttgt aagcttgttc tcctttagta cttgaagggc attatcatct tttgttgctg
     1081 ttttgttctg taaatggggt ttcatgtatt tctgcctaac aagtagcttt tataatactc
     1141 tgaacttttc agaaaattgt tatttgcttt cctacacagt atgagggcta ttgacatcca
     1201 taacactttg atcccaagta agtatagtgt gtctacaatg acaatataag ggagacttga
     1261 tcaatgctag agagtactac ccattcaaaa ctgtaagcta aggtaatttt tatattatgt
     1321 aacagttttc caaagcacct cgaacaggaa gagtaacata aatataaatc tgcattattt
     1381 gaaaagagtt gtaagctttt ttattcatga taaaatttac ataggacaga tataatctct
     1441 ggaaagccat tggtactgac tgtggtaaaa gtacttggtg atacagattc tggtaaaaac
     1501 acatgcatgt tattccatct ctgtgtagta aaaagtatac ttgtacaatg ttttgtactt
     1561 gtatttcatg ttattaaaat agtgatgttc aacctgttgc c
//
