LOCUS       NP_035822                196 aa            linear   ROD 28-APR-2025
DEFINITION  prefoldin subunit 3 [Mus musculus].
ACCESSION   NP_035822
VERSION     NP_035822.2
DBSOURCE    REFSEQ: accession NM_011692.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 196)
  AUTHORS   Cox,B.J., Vollmer,M., Tamplin,O., Lu,M., Biechele,S.,
            Gertsenstein,M., van Campenhout,C., Floss,T., Kuhn,R., Wurst,W.,
            Lickert,H. and Rossant,J.
  TITLE     Phenotypic annotation of the mouse X chromosome
  JOURNAL   Genome Res 20 (8), 1154-1164 (2010)
   PUBMED   20548051
REFERENCE   2  (residues 1 to 196)
  AUTHORS   Xiao,C., Sharp,J.A., Kawahara,M., Davalos,A.R.,
            Difilippantonio,M.J., Hu,Y., Li,W., Cao,L., Buetow,K., Ried,T.,
            Chadwick,B.P., Deng,C.X. and Panning,B.
  TITLE     The XIST noncoding RNA functions independently of BRCA1 in X
            inactivation
  JOURNAL   Cell 128 (5), 977-989 (2007)
   PUBMED   17350580
REFERENCE   3  (residues 1 to 196)
  AUTHORS   Nelson,P.S., Pritchard,C., Abbott,D. and Clegg,N.
  TITLE     The human (PEDB) and mouse (mPEDB) Prostate Expression Databases
  JOURNAL   Nucleic Acids Res 30 (1), 218-220 (2002)
   PUBMED   11752298
REFERENCE   4  (residues 1 to 196)
  AUTHORS   Hemberger,M., Himmelbauer,H., Neumann,H.P., Plate,K.H.,
            Schwarzkopf,G. and Fundele,R.
  TITLE     Expression of the von Hippel-Lindau-binding protein-1 (Vbp1) in
            fetal and adult mouse tissues
  JOURNAL   Hum Mol Genet 8 (2), 229-236 (1999)
   PUBMED   9931330
REFERENCE   5  (residues 1 to 196)
  AUTHORS   Brinke,A., Green,P.M. and Giannelli,F.
  TITLE     Characterization of the gene (VBP1) and transcript for the von
            Hippel-Lindau binding protein and isolation of the highly conserved
            murine homologue
  JOURNAL   Genomics 45 (1), 105-112 (1997)
   PUBMED   9339366
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DV066998.1, BY134471.1, AK077923.1 and BY476349.1.
            
            On Jan 27, 2007 this sequence version replaced NP_035822.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK077923.1, AK008847.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..196
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 38.25 cM"
     Protein         1..196
                     /product="prefoldin subunit 3"
                     /note="VHL-binding protein 1"
                     /calculated_mol_wt=22305
     Site            2
                     /site_type="acetylation"
                     /note="N-acetylalanine.
                     /evidence=ECO:0000250|UniProtKB:P61758; propagated from
                     UniProtKB/Swiss-Prot (P61759.2)"
     Region          51..179
                     /region_name="Prefoldin_3"
                     /note="Prefoldin subunit 3; cd23156"
                     /db_xref="CDD:467472"
     Region          51..90
                     /region_name="coiled coil"
                     /note="coiled coil [structural motif]"
                     /db_xref="CDD:467472"
     Site            order(52,55..56,59,163,166..167,169..171,173..174)
                     /site_type="other"
                     /note="prefoldin/TRiC interface [polypeptide binding]"
                     /db_xref="CDD:467472"
     Site            58
                     /site_type="acetylation"
                     /note="N6-acetyllysine.
                     /evidence=ECO:0000250|UniProtKB:P61758; propagated from
                     UniProtKB/Swiss-Prot (P61759.2)"
     Site            order(79,82..83,86..87,89..90,100..107,109..118,121..125,
                     129..134,143)
                     /site_type="other"
                     /note="prefoldin oligomer interface [polypeptide binding]"
                     /db_xref="CDD:467472"
     Region          137..179
                     /region_name="coiled coil"
                     /note="coiled coil [structural motif]"
                     /db_xref="CDD:467472"
     CDS             1..196
                     /gene="Vbp1"
                     /gene_synonym="VBP-1"
                     /coded_by="NM_011692.2:43..633"
                     /db_xref="CCDS:CCDS41032.1"
                     /db_xref="GeneID:22327"
                     /db_xref="MGI:MGI:1333804"
ORIGIN      
        1 maaakdgcgl etaagngrrl hlgipeavfv edvdsfmkqp gnetadtvlk kldeqyqkyk
       61 fmelnlaqkk rrlkgqipei kqtleilkym qkkkestnsm etrflladnl yckasvpptd
      121 kvclwlganv mleydideaq alleknlsta tknldsleed ldflrdqftt tevnmarvyn
      181 wdvkrrnkdd stknka
//
