LOCUS       NM_012037               2732 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus vesicle amine transport 1 (Vat1), mRNA.
ACCESSION   NM_012037
VERSION     NM_012037.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2732)
  AUTHORS   Jia,L., Chopp,M., Wang,L., Lu,X., Zhang,Y., Szalad,A. and
            Zhang,Z.G.
  TITLE     MiR-34a Regulates Axonal Growth of Dorsal Root Ganglia Neurons by
            Targeting FOXP2 and VAT1 in Postnatal and Adult Mouse
  JOURNAL   Mol Neurobiol 55 (12), 9089-9099 (2018)
   PUBMED   29637443
  REMARK    GeneRIF: miR-34a and its target genes of FOXP2 and VAT1 are
            involved in dorsal root ganglia neuron damage under hyperglycemia.
REFERENCE   2  (bases 1 to 2732)
  AUTHORS   Thompson,C.L., Ng,L., Menon,V., Martinez,S., Lee,C.K.,
            Glattfelder,K., Sunkin,S.M., Henry,A., Lau,C., Dang,C.,
            Garcia-Lopez,R., Martinez-Ferre,A., Pombero,A., Rubenstein,J.L.R.,
            Wakeman,W.B., Hohmann,J., Dee,N., Sodt,A.J., Young,R., Smith,K.,
            Nguyen,T.N., Kidney,J., Kuan,L., Jeromin,A., Kaykas,A., Miller,J.,
            Page,D., Orta,G., Bernard,A., Riley,Z., Smith,S., Wohnoutka,P.,
            Hawrylycz,M.J., Puelles,L. and Jones,A.R.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   3  (bases 1 to 2732)
  AUTHORS   Hayess,K., Kraft,R., Sachsinger,J., Janke,J., Beckmann,G.,
            Rohde,K., Jandrig,B. and Benndorf,R.
  TITLE     Mammalian protein homologous to VAT-1 of Torpedo californica:
            isolation from Ehrlich ascites tumor cells, biochemical
            characterization, and organization of its gene
  JOURNAL   J Cell Biochem 69 (3), 304-315 (1998)
   PUBMED   9581869
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK034795.1.
            
            On Apr 6, 2007 this sequence version replaced NM_012037.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK034795.1, AK145193.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2732              AK034795.1         3-2734
FEATURES             Location/Qualifiers
     source          1..2732
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 65.1 cM"
     gene            1..2732
                     /gene="Vat1"
                     /gene_synonym="VAT-1"
                     /note="vesicle amine transport 1"
                     /db_xref="GeneID:26949"
                     /db_xref="MGI:MGI:1349450"
     exon            1..492
                     /gene="Vat1"
                     /gene_synonym="VAT-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             67..1287
                     /gene="Vat1"
                     /gene_synonym="VAT-1"
                     /note="membrane protein of cholinergic synaptic vesicles;
                     vesicle amine transport protein 1 homolog (T californica)"
                     /codon_start=1
                     /product="synaptic vesicle membrane protein VAT-1 homolog"
                     /protein_id="NP_036167.1"
                     /db_xref="CCDS:CCDS25472.1"
                     /db_xref="GeneID:26949"
                     /db_xref="MGI:MGI:1349450"
                     /translation="MSAEREAAEAATVAAATEAGAETGTGAGEGAPSQPPTVEVASDP
                     QPPPAPEASASASAPPLRCLVLTGFGGYDKVKLQSRPAVPPAPGPGQLTLRVRACGLN
                     FADLMGRQGLYDRLPPLPVTPGMEGAGVVVAVGEGVGDRKAGDRVMVLNRSGMWQEEV
                     TVPSAQTFLMPEAMTFEEAAALLVNYITAYMVLFDFGNLRPGHSVLVHMAAGGVGMAA
                     LQLCRTVENVTVFGTASASKHEVLKENGVTHPIDYHTTDYVDEIKKISPKGVDIVMDP
                     LGGSDTAKGYHLLKPMGKVVTYGMANLLTGPKRNLMAMARTWWNQFSVTALQLLQANR
                     AVCGFHLGYLDGEVELVNSVVTRLVALYNQGHIKPRIDSVWPFEKVADAMKQMQEKKN
                     IGKVLLVPGPEKET"
     exon            493..700
                     /gene="Vat1"
                     /gene_synonym="VAT-1"
                     /inference="alignment:Splign:2.1.0"
     exon            701..871
                     /gene="Vat1"
                     /gene_synonym="VAT-1"
                     /inference="alignment:Splign:2.1.0"
     exon            872..961
                     /gene="Vat1"
                     /gene_synonym="VAT-1"
                     /inference="alignment:Splign:2.1.0"
     exon            962..1203
                     /gene="Vat1"
                     /gene_synonym="VAT-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1204..2732
                     /gene="Vat1"
                     /gene_synonym="VAT-1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgtcccgcc cttcccagct gtgcaccggt tctgtacagc tgggaacgca cgtcgcgagt
       61 ctagccatgt ccgcggagag ggaagcagct gaggcggcca ctgtggcagc ggcgaccgag
      121 gccggggcgg agaccgggac cggagccggg gagggtgcgc cttcgcagcc cccgacagtc
      181 gaggtggcaa gcgacccgca gccacccccg gcccccgaag cgtcagcatc cgcttcggca
      241 ccgccactgc gctgcctggt actcaccggc ttcggtggct acgataaggt gaagctgcag
      301 agccggccgg cggtgccccc ggccccgggt ccgggtcaat tgacgctgcg cgtgcgagcc
      361 tgtgggctca acttcgccga cctcatgggc cgccaagggc tgtacgaccg actaccgcct
      421 ctgccggtca cccccggcat ggagggcgcg ggcgtggtag tggcagtggg cgaaggcgtc
      481 ggcgaccgta aggcagggga tcgggtgatg gtgttgaacc ggtcagggat gtggcaggag
      541 gaagtaactg tgccatcagc ccagactttc ctgatgcctg aggccatgac ctttgaagaa
      601 gctgctgcct tgctggtcaa ttatatcacc gcctacatgg ttctctttga cttcggcaac
      661 ctgagaccgg gccatagcgt cttggtacac atggctgcag gtggcgtggg catggcagcc
      721 ctgcagttgt gccgcaccgt ggagaacgtg acagtgtttg gaacggcctc agccagcaag
      781 cacgaggtgc tgaaggagaa cggggtcaca caccccatcg actaccacac gactgactat
      841 gtggacgaga tcaaaaagat ctcccccaaa ggagtagaca tcgtcatgga ccctctgggt
      901 ggatcagaca cggccaaggg ctaccacctc ctcaaaccca tgggcaaagt tgtcacttac
      961 ggaatggcta acctgctgac gggccccaag cggaacctga tggccatggc ccgcacctgg
     1021 tggaatcagt tcagtgtgac agctctgcag ctgctgcagg ccaaccgagc tgtgtgtggc
     1081 ttccacctgg gctacctgga tggagaggtg gaactcgtca atagcgtggt cacccgcctc
     1141 gtggctctgt acaatcaggg ccacatcaaa cctcgaattg actcagtctg gcccttcgag
     1201 aaggtggcag atgcaatgaa acagatgcag gagaagaaga acataggcaa agtcctcctg
     1261 gttcctgggc ctgagaagga gacctagggc cagagggctg agggccctgg agagccgggg
     1321 agggagaaga tgggaagtcc tgtcgtgttg cccaccagcc tctcacattt catcctgtca
     1381 cgatgctcta ccctccctcc ctcccccaga gaaggtctct gctgatgact gcttccctgc
     1441 tctgagctcg ctcttgccct tcgctcaggg ctctccctcc cccccacccc ttcctgccct
     1501 caggagaggt tgggaagtga ccacttggat gtctgggccc tgccaagggg acaggggggg
     1561 tcagcaggag gctggctgct tcctgccctc ccccctctcc ctgggcctac catgctgctt
     1621 ttgtgccaag gttagccaat ccctccctgc cctatcctgt gtgcttccac ctcagcctca
     1681 tcctccctcc tgccccaccc ccacccaaag aatctatgcg tcagctcagg acgtggggcc
     1741 gatctgtgtg agtccagcat gtacctgtgt cccccgtagt atccccgcag cccaggccga
     1801 cgaggcccac ccctggactt gatcagtatt caaccttgtc tcctgtcccc aatgtcgtaa
     1861 gcacaattag acttcttccg gcttgagttt gctgcctcct acagcaagga caggaatcag
     1921 accgactccc tagcttacgc tctgggaggg gtactgggta ccccaccctt cactgaggcc
     1981 tttggatttg tctcagtgcc ttagcatctg aaaacctgtg cttgtatatg tgtgtgtatg
     2041 tgtaggggca gcccctatct ctggctcctt ttccaccctt ctccccagtg ccttcctcgt
     2101 cctggtggag ctgaggccta ctcctcccca gtccaacact gccaaaaatc tgtgtatgtg
     2161 ccaggggtcg ggggtctggg ggtaggggac agctccagcc tctggggacc aattgctttt
     2221 actgtggtct gtggcctgtc ctgtctctgt cagtggagaa gaaaggcagt gagctggatc
     2281 agccagagtt ctgggagaca acgctgggtc ttattctggg accaaagtga gaattcaagc
     2341 acatttcttt cctttgctat gtagggaggc tgctgccttc ccagagcctg gaggcagctc
     2401 tgctgttcag ccccaaactt tgtttacact gctagggaag gaggagctcc ggcaagggaa
     2461 taactaggct ggttaaaaga gtcagggcta ctggagccaa ggtggggacc tttgaggcta
     2521 ggtgggggtc acctgctgct tctgagcttg gattagagaa agctcttaac tccagccact
     2581 gtcagaggga gtgtggaggg agggacccgg cctctctgtt gtcaaattga ggcctccatg
     2641 tgggaagtgt gatttctgct tttgtgtccc atccccaccc caccccatta ccacagctgc
     2701 ctttgtgtct gtgtcaataa aaagccaaac cc
//
