LOCUS       NM_011690               4224 bp    mRNA    linear   ROD 31-MAY-2023
DEFINITION  Mus musculus valyl-tRNA synthetase 1 (Vars1), mRNA.
ACCESSION   NM_011690
VERSION     NM_011690.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4224)
  AUTHORS   Liu X, Jiao Y, Cao Y, Deng N, Ma Y, Hasty KA, Kang A, Chen H,
            Stuart JM and Gu W.
  TITLE     Decreased expression levels of Ifi genes is associated to the
            increased resistance to spontaneous arthritis disease in mice
            deficiency of IL-1RA
  JOURNAL   BMC Immunol 17 (1), 25 (2016)
   PUBMED   27480124
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4224)
  AUTHORS   Xie T, Rowen L, Aguado B, Ahearn ME, Madan A, Qin S, Campbell RD
            and Hood L.
  TITLE     Analysis of the gene-dense major histocompatibility complex class
            III region and its comparison to mouse
  JOURNAL   Genome Res 13 (12), 2621-2636 (2003)
   PUBMED   14656967
REFERENCE   3  (bases 1 to 4224)
  AUTHORS   Mootha VK, Bunkenborg J, Olsen JV, Hjerrild M, Wisniewski JR, Stahl
            E, Bolouri MS, Ray HN, Sihag S, Kamal M, Patterson N, Lander ES and
            Mann M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   4  (bases 1 to 4224)
  AUTHORS   Carninci P, Waki K, Shiraki T, Konno H, Shibata K, Itoh M, Aizawa
            K, Arakawa T, Ishii Y, Sasaki D, Bono H, Kondo S, Sugahara Y, Saito
            R, Osato N, Fukuda S, Sato K, Watahiki A, Hirozane-Kishikawa T,
            Nakamura M, Shibata Y, Yasunishi A, Kikuchi N, Yoshiki A, Kusakabe
            M, Gustincich S, Beisel K, Pavan W, Aidinis V, Nakagawara A, Held
            WA, Iwata H, Kono T, Nakauchi H, Lyons P, Wells C, Hume DA,
            Fagiolini M, Hensch TK, Brinkmeier M, Camper S, Hirota J, Mombaerts
            P, Muramatsu M, Okazaki Y, Kawai J and Hayashizaki Y.
  TITLE     Targeting a complex transcriptome: the construction of the mouse
            full-length cDNA encyclopedia
  JOURNAL   Genome Res 13 (6B), 1273-1289 (2003)
   PUBMED   12819125
REFERENCE   5  (bases 1 to 4224)
  AUTHORS   van Kooij M, de Groot K, van Vugt H, Aten J and Snoek M.
  TITLE     Genotype versus phenotype: conflicting results in mapping a lung
            tumor susceptibility locus to the G7c recombination interval in the
            mouse MHC class III region
  JOURNAL   Immunogenetics 53 (8), 656-661 (2001)
   PUBMED   11797099
REFERENCE   6  (bases 1 to 4224)
  AUTHORS   Fijneman RJ, Oomen LC, Snoek M and Demant P.
  TITLE     A susceptibility gene for alveolar lung tumors in the mouse maps
            between Hsp70.3 and G7 within the H2 complex
  JOURNAL   Immunogenetics 41 (2-3), 106-109 (1995)
   PUBMED   7806281
REFERENCE   7  (bases 1 to 4224)
  AUTHORS   Snoek M, van Vugt H and Groot PC.
  TITLE     New microsatellite size variants as markers for a cross-over
            hotspot in the C4-H-2D region
  JOURNAL   Mamm Genome 5 (3), 174-176 (1994)
   PUBMED   8199408
REFERENCE   8  (bases 1 to 4224)
  AUTHORS   Gasser DL, Sternberg NL, Pierce JC, Goldner-Sauve A, Feng H, Haq
            AK, Spies T, Hunt C, Buetow KH and Chaplin DD.
  TITLE     P1 and cosmid clones define the organization of 280 kb of the mouse
            H-2 complex containing the Cps-1 and Hsp70 loci
  JOURNAL   Immunogenetics 39 (1), 48-55 (1994)
   PUBMED   7993390
REFERENCE   9  (bases 1 to 4224)
  AUTHORS   Lund T, Shaikh S, Kendall E, Campbell RD, Hattori M, Makino S and
            Cooke A.
  TITLE     RFLP analysis of the MHC class III region defines unique haplotypes
            for the non-obese diabetic, cataract Shionogi and the non-obese
            non-diabetic mouse strains
  JOURNAL   Diabetologia 36 (8), 727-733 (1993)
   PUBMED   8104833
REFERENCE   10 (bases 1 to 4224)
  AUTHORS   Lafuse WP, Lanning D, Spies T and David CS.
  TITLE     PFGE mapping and RFLP analysis of the S/D region of the mouse H-2
            complex
  JOURNAL   Immunogenetics 36 (2), 110-116 (1992)
   PUBMED   1351875
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ080276.1, BY775300.1, AK157814.1, AK019157.1 and BB070705.1.
            
            [WARNING] On Oct 18, 2023 this sequence was replaced by
            NM_011690.4.
            
            On Aug 4, 2009 this sequence version replaced NM_011690.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK154823.1, BC053703.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-94                CJ080276.1         2-95
            95-144              BY775300.1         52-101
            145-532             AK157814.1         2-389
            533-3117            AK157814.1         391-2975
            3118-4219           AK019157.1         1515-2616
            4220-4224           BB070705.1         250-254
FEATURES             Location/Qualifiers
     source          1..4224
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 18.54 cM"
     gene            1..4224
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /note="valyl-tRNA synthetase 1"
                     /db_xref="GeneID:22321"
                     /db_xref="MGI:MGI:90675"
     exon            1..326
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            327..745
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            746..880
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            881..1019
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            1020..1141
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            1142..1226
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            1227..1327
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            1328..1455
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            1456..1620
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            1621..1702
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            1703..1822
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            1823..1931
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            1932..2026
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            2027..2117
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            2118..2242
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            2243..2346
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            2347..2505
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            2506..2596
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            2597..2702
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            2703..2773
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            2774..2899
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            2900..3004
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            3005..3073
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            3074..3152
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            3153..3280
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            3281..3436
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            3437..3643
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            3644..3755
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            3756..4081
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            4082..4224
                     /gene="Vars1"
                     /gene_synonym="Bat6; D17H6S56E; G7a; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcgcctgac ccagacccag gctcgtcccg gcacgcgggt tcccgtctcc gtgctgcacg
       61 agccactctg gcccctgctt gacccgtccg gcagcggtgg gccgcgcacg gaccctcggg
      121 atcgcgcacg cacaggcggg gcccggcagc cctgcgagga cccgagtccg gaaacgtgcg
      181 ctgtcacaaa gggggggaca cgtgggtgcc gctgtcccgg ccgcgttctc ccgcagcggg
      241 agagctgcct ccgctgcccg ccacctccac cccggccgcc ctgtggggcc gcggccgtag
      301 ccggccgagt gtgatcgccg ccttcagtca ctgcaccgcg ttcggaccct gcacagccat
      361 gtccatcctc tacgtctctc ctcaccccga cgccttcccc agcctccgag ccctcatcgc
      421 tgcccgatac ggggaagctg gtgacggtcc cgggtgggga ggccctcacc cccgcatctg
      481 cttgcagcct cccccgagca gccggactcc attccctccg cctcgcctgc ccgccctgga
      541 gcagggacct ggcggcctgt gggtgtgggg ggccccggct gtagctcagc tgttgtggcc
      601 tgcaggcctg gggggacccg ggggcagccg ggcagctgtc ctggtccagc agtgggtcag
      661 ttatgctgac acggagctca tacccgctgc ctgcggggcg accctgcctg ccctgggact
      721 tcgaggtcct ggtcaggatc cccaggctgc ccttggggcc ctgggcaagg ccttgaaccc
      781 cttggaggac tggctgcggc tgcacaccta cctggctgga gatgccccca ctctggctga
      841 cttagctgct gtgacagcct tactgctgcc tttccgatac gttctggacc cttctgcccg
      901 ccggatctgg ggcaatgtga ctcgctggtt taacacttgt gtccggcaac cggaattccg
      961 ggctgtgctg ggagaagtgg ccctgtactc gggggccagg tctgtcactc aacagccagg
     1021 ctctgaggtc atcgcacccc aaaaaacacc cgcgcagctc aaaaaagagg caaagaaacg
     1081 ggagaaacta gagaaattcc agcagaagca gaagacccag cagcagcccc cgcacggaga
     1141 gaagaaacca aaaccagaga agaaggagaa acgggaccct ggggtcatta cctatgacct
     1201 ccctacccca ccgggggaga agaaagatgt aagtggcgcc atgcccgact cctacagccc
     1261 tcagtatgtg gaggctgcct ggtatccatg gtgggagcgg cagggcttct tcaagccaga
     1321 gtacgggcgt cctagtgtgt cagcaccaaa tccccggggt gtcttcatga tgtgcatccc
     1381 accccccaac gtgacaggct ccctgcacct gggccacgca ctcaccaacg ccatccagga
     1441 ctccctgact cgatggcacc gcatgcgtgg ggagaccacc ctatggaacc caggctgtga
     1501 ccatgcaggc attgccaccc aggtggtggt ggaaaagaag ctctggaaag agcggggtct
     1561 gaaccggcac cagctgggcc gcgaggcctt tcttgaggag gtctggaagt ggaaagccga
     1621 gaagggtgac aggatttacc accaattaaa gaaacttggc agctccttgg actgggatcg
     1681 agcctgcttc accatggatc ctaaattgtc agcaactgtg acagaggcct ttgttaggct
     1741 ccacgaagaa ggggtcatct accgtagcac ccgcctggtc aactggtcct gcaccctcaa
     1801 ctcagccatt tctgacattg aggtggataa gaaggagctg acaggccgca ccctgcttcc
     1861 tgtgcctggc tacaaggaga aggtggagtt tggggtcctt gtgtcctttg cctacaaggt
     1921 ccaaggctca gacagcgacg aggaggtggt ggtggcaaca acccggattg agaccatgct
     1981 gggagacgtg gctgtagctg tgcaccccaa ggatcccaga taccagcact taaagggaaa
     2041 gtgtgtcgtc cacccattct tgtcccggag ccttcccatc gtcttcgatg actttgtaga
     2101 catggagttt ggcacaggtg ccgtgaagat caccccggca catgaccaaa atgactatga
     2161 ggttgggcag cgacacaggc tcgaggccat tagcatcatg gactcaaagg gggccctcat
     2221 caatgtgcct ccacctttcc tgggcctgcc caggtttgag gccaggaagg ctgtgctggc
     2281 ggcactgaag gagcggggcc tgttccgtgg agtcaaggac aaccccatgg tggtgccgct
     2341 ttgcaaccgc tccaaggatg tggtggagcc tctgttaagg ccacaatggt acgtgcgctg
     2401 tggggagatg gctcaggctg ccagtgctgc tgtgacccgg ggtgacctcc gtatactgcc
     2461 tgaggcccat caacggacgt ggcattcttg gatggacaac atcagagact ggtgcatctc
     2521 tcggcagctg tggtggggcc accgaatccc tgcctacttt atcaccgtcc atgacccggc
     2581 agtaccccct ggggaggacc ctgatgggcg gtactgggta agcggacgca ctgaagcaga
     2641 ggcccgagag aaggcagcac gggagtttgg agtgtcccct gacaagatca gccttcagca
     2701 agatgaggat gtgttggaca cctggttctc ctccggtctc tttcccttct ccatctttgg
     2761 ctggcccaat cagtcagaag acctcagtgt gttctaccct gggaccctgt tggagacagg
     2821 ccatgatatc ctcttcttct gggtggcccg gatggtcatg ctcggcctga agctcactgg
     2881 gaagctgccc ttcagagagg tctatctcca tgcaatcgtg cgtgatgctc atggcaggaa
     2941 gatgagcaag tctcttggca atgtcatcga ccccctggat gtcatccatg gagtttcctt
     3001 gcagggcctc tatgaccaac tactgaacag caacctggat cccagtgagg tggagaaagc
     3061 caaagaagga cagaaggccg actttccagc agggattccc gagtgtggca ctgatgccct
     3121 acgctttgga ctctgtgcct acacatccca aggtcgagac atcaacctgg atgtgaacag
     3181 gatcctgggg taccgtcact tctgcaacaa actctggaat gctaccaagt ttgccctgcg
     3241 cggccttggg aagggctttg tgccctcagc aacctccaag cctgaagggc acgagagcct
     3301 ggtggaccgc tggatccgca gccgcctaac tgaggccgtg aggctcagca atgaaggctt
     3361 ccaggcttac gatttcccgg ccatcaccac cgcccagtac agcttttggc tctatgagct
     3421 ctgtgatgtc tatttggagt gtctaaaacc tgtgctgaat ggagtggacc aggtggcggc
     3481 agagtgtgct cggcagaccc tctacacctg cctggatgtt ggcctgcggc tgctctcgcc
     3541 cttcatgccc tttgtcacag aggagctatt ccagagactg ccccggcgga caccaaaagc
     3601 gcctgctagc ctctgtgtca ccccgtaccc agagccctca gagtgctcct ggaaggaccc
     3661 tgaagctgaa gctgctcttg aactagctct gagcatcact cgagctgtgc gctccctgcg
     3721 tgctgactac aacctgaccc gcaccaggcc cgactgtttc ttggaagtag ccgatgaggc
     3781 cacaggtgcc ttggcctcgg cagtgtcggg ctacgtgcag gctctggcca gtgcgggcgt
     3841 ggtggctgtc ctcgccctgg gtgctcctgc accgcagggc tgcgctgtag ctgtggcttc
     3901 tgaccgctgc tccatccacc tgcagctgca ggggctagtg gacccagccc gggagttggg
     3961 caagctgcag gccaagcgaa gtgaggcaca gcggcaggct cagcggctgc aggagcgccg
     4021 tgctgcctcc agctactcag caaaggtgcc ccttgaggtc caggaggcag atgaagcgaa
     4081 gttgcaacag acagaggcgg agctcaggaa ggtggatgag gccatcgccc tgttccagaa
     4141 gatgctgtga ccccccattc caaccctcag cccccagtgt tccatcaaca gggatggcag
     4201 caataaaata ttttcccaac attc
//
