LOCUS       NM_009498               2115 bp    mRNA    linear   ROD 29-JUL-2024
DEFINITION  Mus musculus vesicle-associated membrane protein 3 (Vamp3), mRNA.
ACCESSION   NM_009498
VERSION     NM_009498.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2115)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2115)
  AUTHORS   Dai,X., Li,L., Yan,X., Fan,Q., Wang,R., Zhang,W., Chen,W., Liu,Y.,
            Meng,J. and Wang,J.
  TITLE     Myeloid Vamp3 deletion attenuates CFA-induced inflammation and pain
            in mice via ameliorating macrophage infiltration and inflammatory
            cytokine production
  JOURNAL   Front Immunol 14, 1239592 (2023)
   PUBMED   37965323
  REMARK    GeneRIF: Myeloid Vamp3 deletion attenuates CFA-induced inflammation
            and pain in mice via ameliorating macrophage infiltration and
            inflammatory cytokine production.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2115)
  AUTHORS   Min,J., Li,Y., Li,X., Wang,M., Li,H., Bi,Y., Xu,P., Liu,W., Ye,X.
            and Li,J.
  TITLE     The circRNA circVAMP3 restricts influenza A virus replication by
            interfering with NP and NS1 proteins
  JOURNAL   PLoS Pathog 19 (8), e1011577 (2023)
   PUBMED   37603540
  REMARK    GeneRIF: The circRNA circVAMP3 restricts influenza A virus
            replication by interfering with NP and NS1 proteins.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2115)
  AUTHORS   Han,J., Yoon,S. and Park,H.
  TITLE     Endocytic BDNF secretion regulated by Vamp3 in astrocytes
  JOURNAL   Sci Rep 11 (1), 21203 (2021)
   PUBMED   34707216
  REMARK    GeneRIF: Endocytic BDNF secretion regulated by Vamp3 in astrocytes.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2115)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2115)
  AUTHORS   Fratti,R.A., Chua,J. and Deretic,V.
  TITLE     Cellubrevin alterations and Mycobacterium tuberculosis phagosome
            maturation arrest
  JOURNAL   J Biol Chem 277 (19), 17320-17326 (2002)
   PUBMED   11825909
  REMARK    GeneRIF: Cellubrevin alterations and Mycobacterium tuberculosis
            phagosome maturation arrest.
REFERENCE   7  (bases 1 to 2115)
  AUTHORS   Yang,C., Mora,S., Ryder,J.W., Coker,K.J., Hansen,P., Allen,L.A. and
            Pessin,J.E.
  TITLE     VAMP3 null mice display normal constitutive, insulin- and
            exercise-regulated vesicle trafficking
  JOURNAL   Mol Cell Biol 21 (5), 1573-1580 (2001)
   PUBMED   11238894
REFERENCE   8  (bases 1 to 2115)
  AUTHORS   Gerst,J.E.
  TITLE     SNAREs and SNARE regulators in membrane fusion and exocytosis
  JOURNAL   Cell Mol Life Sci 55 (5), 707-734 (1999)
   PUBMED   10379359
  REMARK    Review article
REFERENCE   9  (bases 1 to 2115)
  AUTHORS   Bernstein,A.M. and Whiteheart,S.W.
  TITLE     Identification of a cellubrevin/vesicle associated membrane protein
            3 homologue in human platelets
  JOURNAL   Blood 93 (2), 571-579 (1999)
   PUBMED   9885218
REFERENCE   10 (bases 1 to 2115)
  AUTHORS   Martin,S., Tellam,J., Livingstone,C., Slot,J.W., Gould,G.W. and
            James,D.E.
  TITLE     The glucose transporter (GLUT-4) and vesicle-associated membrane
            protein-2 (VAMP-2) are segregated from recycling endosomes in
            insulin-sensitive cells
  JOURNAL   J Cell Biol 134 (3), 625-635 (1996)
   PUBMED   8707843
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK051272.1.
            
            On Apr 6, 2007 this sequence version replaced NM_009498.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK051272.1, SRR1660815.121912.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2115              AK051272.1         2-2116
FEATURES             Location/Qualifiers
     source          1..2115
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 81.53 cM"
     gene            1..2115
                     /gene="Vamp3"
                     /gene_synonym="ceb; D130027G05Rik; VAMP-3"
                     /note="vesicle-associated membrane protein 3"
                     /db_xref="GeneID:22319"
                     /db_xref="MGI:MGI:1321389"
     exon            1..80
                     /gene="Vamp3"
                     /gene_synonym="ceb; D130027G05Rik; VAMP-3"
                     /inference="alignment:Splign:2.1.0"
     CDS             79..390
                     /gene="Vamp3"
                     /gene_synonym="ceb; D130027G05Rik; VAMP-3"
                     /note="synaptobrevin-3; cellubrevin"
                     /codon_start=1
                     /product="vesicle-associated membrane protein 3"
                     /protein_id="NP_033524.1"
                     /db_xref="CCDS:CCDS18979.1"
                     /db_xref="GeneID:22319"
                     /db_xref="MGI:MGI:1321389"
                     /translation="MSTGVPSGSSAATGSNRRLQQTQNQVDEVVDIMRVNVDKVLERD
                     QKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKMWAIGISVLVIIVIIIIVWCV
                     S"
     exon            81..162
                     /gene="Vamp3"
                     /gene_synonym="ceb; D130027G05Rik; VAMP-3"
                     /inference="alignment:Splign:2.1.0"
     exon            163..321
                     /gene="Vamp3"
                     /gene_synonym="ceb; D130027G05Rik; VAMP-3"
                     /inference="alignment:Splign:2.1.0"
     exon            322..373
                     /gene="Vamp3"
                     /gene_synonym="ceb; D130027G05Rik; VAMP-3"
                     /inference="alignment:Splign:2.1.0"
     exon            374..2115
                     /gene="Vamp3"
                     /gene_synonym="ceb; D130027G05Rik; VAMP-3"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      2115
                     /gene="Vamp3"
                     /gene_synonym="ceb; D130027G05Rik; VAMP-3"
                     /note="putative"
ORIGIN      
        1 gcccatctcc tcagcctcgg ttgcctgcag cgcgagtccg tcgaccctcg gccattcgcc
       61 gccgccaccg ccgccaaaat gtctacaggt gtgccttcgg ggtcaagtgc tgccactggc
      121 agtaatcgaa gactccagca gacacaaaat caagtagatg aggtggttga catcatgaga
      181 gtcaatgtgg ataaggtgtt agaaagagac cagaagctct cggagctaga tgaccgcgca
      241 gatgcactgc aggcaggtgc ctcgcagttt gaaacaagtg ctgccaagtt gaagagaaag
      301 tattggtgga agaactgcaa gatgtgggcg atagggatca gtgtcctggt gatcattgtc
      361 atcatcatca tcgtgtggtg tgtctcttaa tgaagaaccg atgaaactga agcccgatat
      421 tcaggatctt cttcaagact ttctacttag aacctgccgt gttatcgagc ttacctattg
      481 ttttttttcc aaatgattat ttttgttagt ttacatacag tttagtgcct agaaaatgtg
      541 cctttgtttt tcatatacac tccaaactgg aggtgtgacc taccctcccc acattttgca
      601 cagtgccttt acagatttct ggactgggaa agaggacttg tgtagttctg agtgctgaat
      661 ggaggtggat gttgtcactc aagatgactt gttgtggatt ccaggaaggg ggttttgttc
      721 aaggcagctg tccccacatc tgacatcatc ttcaaaacca cattttaaac ttttgggtaa
      781 ttagattcct aacttggacc ttccaagaag aacactactg cctaacagca atgggtgaca
      841 atagcagggt gtgccttatt ttgatagcta ggaaactgtt ctttaagatt attctccgtt
      901 tgtaagcact actgactccc gctgtattta agatgctggt gaagagctca tgctcttatg
      961 ttagatatga ctatgtttac tttcttgttc ttgttgtata tcactcctaa aatagtattt
     1021 taaccagaaa taacccttta agaagttttt atagaactat gaccaaagtt tctattttgc
     1081 caaaagttaa gtacaaataa attgccccaa tagatacatt caaataagtg ccaaatgtaa
     1141 ctcaaggtgt cctttaagaa aaatgttaat actgtgagag cgagccttca acatgtcggc
     1201 agtccatcct gtgaaatgct atagagaagg ctagtcattc tgatttggtt tcttctttag
     1261 agctatggag gtgggctcag atcacacctg tagacaagat acttagccag cagtttgtag
     1321 actgagctag gctgtggtct ctagtgcgat gtgagcagta gccgtgcagc ctcaccaagg
     1381 catcagtctg cacagagttc cagaagactg tgtactgctt gtactcatct ctgtcttatg
     1441 cttgaggtaa gccaccggtc actcgtagag gatagctaac cagagatgcc tggtgctctt
     1501 agaatgtagc cattgctgtc tgggacagtt tcattgttta tatgagactt tcatcaaggc
     1561 ttggttcaaa gacaggagtt caggcatggg tggaattgag gaagtggtga agggaaagct
     1621 gcttgcctat ggcagtgcca ctagaatgtc ctgaaatctg tgtttgtgtg taaagcagca
     1681 ttactcaaga tgtcatagaa tctggttcta gttttttgtt tttgttttgt tttttgagac
     1741 agggtttctc tgtatagccc ttgctgtcct ggaactcact ttgtagacca ggctggctcg
     1801 aactcaaaaa tccgcctgcc tctgcctccc aagtgcaggg attaaaggcg tgtgccacca
     1861 acgcccaact ggttctagtt ttttatctgt tcccctaaca ttactgaaac aatacagatg
     1921 ttgaagatat gccttgccgc atcagcctag ggcttctgtc ctggtctgac ctcacaactt
     1981 tggtgctgtc tcctcatatt ctgtcccatg taactcagtg gctcctgtat taacacagtg
     2041 atacctcgct tctctgtgca tttagctggg aatgttcccg gtatggtgac cagaataaag
     2101 ttgtttatta acatg
//
