LOCUS       NM_001290994            7540 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus ubiquitin specific peptidase 29 (Usp29), transcript
            variant 1, mRNA.
ACCESSION   NM_001290994
VERSION     NM_001290994.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7540)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 7540)
  AUTHORS   Chen,Z., Hu,F., Zhang,Y., Zhang,L., Wang,T., Kong,C., Hu,H.,
            Guo,J., Chen,Q., Yu,B., Liu,Y., Zou,J., Zhou,J. and Qiu,T.
  TITLE     Ubiquitin-specific protease 29 attenuates hepatic
            ischemia-reperfusion injury by mediating TGF-beta-activated kinase
            1 deubiquitination
  JOURNAL   Front Immunol 14, 1167667 (2023)
   PUBMED   37304282
  REMARK    GeneRIF: Ubiquitin-specific protease 29 attenuates hepatic
            ischemia-reperfusion injury by mediating TGF-beta-activated kinase
            1 deubiquitination.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 7540)
  AUTHORS   Liu,W., Tang,P., Wang,J., Ye,W., Ge,X., Rong,Y., Ji,C., Wang,Z.,
            Bai,J., Fan,J., Yin,G. and Cai,W.
  TITLE     Extracellular vesicles derived from melatonin-preconditioned
            mesenchymal stem cells containing USP29 repair traumatic spinal
            cord injury by stabilizing NRF2
  JOURNAL   J Pineal Res 71 (4), e12769 (2021)
   PUBMED   34562326
  REMARK    GeneRIF: Extracellular vesicles derived from
            melatonin-preconditioned mesenchymal stem cells containing USP29
            repair traumatic spinal cord injury by stabilizing NRF2.
REFERENCE   4  (bases 1 to 7540)
  AUTHORS   Hou,J.B., Shen,Q.N., Wan,X., Liu,X.K., Yu,Y., Li,M., Gao,W.W. and
            Zhao,B.
  TITLE     Ubiquitin-Specific Protease 29 Exacerbates Cerebral
            Ischemia-Reperfusion Injury in Mice
  JOURNAL   Oxid Med Cell Longev 2021, 6955628 (2021)
   PUBMED   34824671
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7540)
  AUTHORS   Tu,R., Kang,W., Yang,M., Wang,L., Bao,Q., Chen,Z., Dong,Y.,
            Wang,J., Jiang,J., Liu,H. and Qing,G.
  TITLE     USP29 coordinates MYC and HIF1alpha stabilization to promote tumor
            metabolism and progression
  JOURNAL   Oncogene 40 (46), 6417-6429 (2021)
   PUBMED   34601505
REFERENCE   6  (bases 1 to 7540)
  AUTHORS   Monk,D., Smith,R., Arnaud,P., Preece,M.A., Stanier,P.,
            Beechey,C.V., Peters,J., Kelsey,G. and Moore,G.E.
  TITLE     Imprinted methylation profiles for proximal mouse chromosomes 11
            and 7 as revealed by methylation-sensitive representational
            difference analysis
  JOURNAL   Mamm Genome 14 (12), 805-816 (2003)
   PUBMED   14724735
REFERENCE   7  (bases 1 to 7540)
  AUTHORS   Choi,J.D., Underkoffler,L.A., Collins,J.N., Marchegiani,S.M.,
            Terry,N.A., Beechey,C.V. and Oakey,R.J.
  TITLE     Microarray expression profiling of tissues from mice with
            uniparental duplications of chromosomes 7 and 11 to identify
            imprinted genes
  JOURNAL   Mamm Genome 12 (10), 758-764 (2001)
   PUBMED   11668390
REFERENCE   8  (bases 1 to 7540)
  AUTHORS   Kim,J., Bergmann,A., Wehri,E., Lu,X. and Stubbs,L.
  TITLE     Imprinting and evolution of two Kruppel-type zinc-finger genes,
            ZIM3 and ZNF264, located in the PEG3/USP29 imprinted domain
  JOURNAL   Genomics 77 (1-2), 91-98 (2001)
   PUBMED   11543637
REFERENCE   9  (bases 1 to 7540)
  AUTHORS   Kim,J., Noskov,V.N., Lu,X., Bergmann,A., Ren,X., Warth,T.,
            Richardson,P., Kouprina,N. and Stubbs,L.
  TITLE     Discovery of a novel, paternally expressed ubiquitin-specific
            processing protease gene through comparative analysis of an
            imprinted region of mouse chromosome 7 and human chromosome 19q13.4
  JOURNAL   Genome Res 10 (8), 1138-1147 (2000)
   PUBMED   10958632
REFERENCE   10 (bases 1 to 7540)
  AUTHORS   Szeto,I.Y., Li,L.L. and Surani,M.A.
  TITLE     Ocat, a paternally expressed gene closely linked and transcribed in
            the opposite direction to Peg3
  JOURNAL   Genomics 67 (2), 221-227 (2000)
   PUBMED   10903847
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC157657.2 and AC149277.11.
            
            Transcript Variant: This variant (1) represents the longest
            transcript. Variants 1-4 all encode the same protein.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            CDS exon combination :: ERR3363658.3095641.1 [ECO:0000331]
            RNAseq introns       :: partial sample support SAMN01164137,
                                    SAMN01164138 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-720               AC157657.2         65389-66108         c
            721-790             AC157657.2         59057-59126         c
            791-943             AC157657.2         57746-57898         c
            944-1038            AC149277.11        76414-76508         c
            1039-1105           AC149277.11        52972-53038         c
            1106-1189           AC149277.11        52111-52194         c
            1190-1265           AC149277.11        32497-32572         c
            1266-1452           AC149277.11        24645-24831         c
            1453-7540           AC149277.11        17575-23662         c
FEATURES             Location/Qualifiers
     source          1..7540
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 4.04 cM"
     gene            1..7540
                     /gene="Usp29"
                     /gene_synonym="Ocat"
                     /note="ubiquitin specific peptidase 29"
                     /db_xref="GeneID:57775"
                     /db_xref="MGI:MGI:1888998"
     exon            1..720
                     /gene="Usp29"
                     /gene_synonym="Ocat"
                     /inference="alignment:Splign:2.1.0"
     exon            721..790
                     /gene="Usp29"
                     /gene_synonym="Ocat"
                     /inference="alignment:Splign:2.1.0"
     exon            791..943
                     /gene="Usp29"
                     /gene_synonym="Ocat"
                     /inference="alignment:Splign:2.1.0"
     exon            944..1038
                     /gene="Usp29"
                     /gene_synonym="Ocat"
                     /inference="alignment:Splign:2.1.0"
     exon            1039..1105
                     /gene="Usp29"
                     /gene_synonym="Ocat"
                     /inference="alignment:Splign:2.1.0"
     exon            1106..1189
                     /gene="Usp29"
                     /gene_synonym="Ocat"
                     /inference="alignment:Splign:2.1.0"
     exon            1190..1265
                     /gene="Usp29"
                     /gene_synonym="Ocat"
                     /inference="alignment:Splign:2.1.0"
     exon            1266..1452
                     /gene="Usp29"
                     /gene_synonym="Ocat"
                     /inference="alignment:Splign:2.1.0"
     exon            1453..7540
                     /gene="Usp29"
                     /gene_synonym="Ocat"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4873..4878
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Usp29"
                     /gene_synonym="Ocat"
                     /note="hexamer: ATTAAA"
     polyA_site      4892
                     /gene="Usp29"
                     /gene_synonym="Ocat"
                     /note="major polyA site"
     regulatory      7517..7522
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Usp29"
                     /gene_synonym="Ocat"
                     /note="hexamer: AATAAA"
     polyA_site      7537
                     /gene="Usp29"
                     /gene_synonym="Ocat"
ORIGIN      
        1 acggagttga cgtcaacgga gtcagtgtta ggggccccca agcagagtct ggaaaagggg
       61 gatgggatgt gggtgtgaag ggatgcagcc cccccaaaag aaatcggggt gaatcagaaa
      121 tacctactaa tgatgcccca atgcaaaacc tgagaagaga gagagggaaa aacgacaagc
      181 atatatttgt ctaaaatcgg gaaaaaagaa aaaccatgaa aaatcgagac agaaacacat
      241 acgttgaggt ctaaccacga acgataaagg tggaagaaag gacttttctg cctgcaacac
      301 ccaagcacta agctaatttc cttaataaac gaagagctat tggaaaccaa caagggaagg
      361 acaaaagcaa agcaaaaaag ggggcaaaag agaccgcaag tcacaggaca atgcaaatgg
      421 ctggaagaat cttgacctga ctgtctgcat agcgaaacgc caacctgaga taccgggtga
      481 aggcggttta tggcagcgcg ctgaatcgca tgtggtcaac catcattgcg tgaatccact
      541 gcatagaata gcaagaaatt gcgaggagag caagcaggta gattaccaag cctgcctctg
      601 atagaagaca ttcctatgtc accaggaaaa ataacggagg tatcgctgcc ataaaggacc
      661 tggatcggaa tagatcccaa tgaaataaaa cccgttgccg aagtttgtag aaacgaaatg
      721 gttcacccta ctccccattt caacaccttt aaaagatatt ttaaagtatt ttgagtatct
      781 gcagagccag ttgttgcttc caagcgtaca gtgccatttt cctgaggcta tatgacctgt
      841 gataccataa caggctgaag gctcaagcaa atgaaaattc cagctgttcc ctatcaagtc
      901 tgacaccgaa gacatttgcc gagatgtaaa acgatgctac cagaagagag cttcaattgg
      961 atcttcagca ggtgatgcca tcttgtccag gggctctttt gtcttgcact gtggacactc
     1021 agcactggag aattctttgc cagcttggtc tacagagtga gttccaggac agccagagct
     1081 ctacaggaaa aacctcatct caaaggtctt ggaggtggaa cttacatcgt cacacttggc
     1141 tgaaggctcc tttatcctct gagccacctc actggcccca caaatccagt taagagcctg
     1201 cagccggacc gtgagccgcc gtgagccgcc ttctacggcc gtgatattcc taaatagaaa
     1261 cttgggactt gggtctgcgt ctggaatctg caatcagaaa gccagcactt acaactttgg
     1321 cgactcaacc tcatattgcg actgtctcat ttgcgtgaga gactagaggt tggcagaaac
     1381 ttccattgtc tcagcctcac cagtgaaaag agcagaagcc ccggagccca acgccacagc
     1441 attttacttc tgattgtgca tgcttttttg tgaagaaaga atggctcacc taaagataaa
     1501 tggtttggtc cagatccgca gcacaaacag gagcaagcac accagggcat ctcagtggaa
     1561 ggaagcagtc atcgaaatag tagaaagaaa acagaaagtt aatctggtgg tttctttcaa
     1621 gttggaagaa aggagaaggg tgtttcagct gggtgataat gttacaggcg tagtggttag
     1681 tggtgagctg ggactgtatc atctggattt aactttgaga gacgacacat ccttactcat
     1741 cgacaagtta tcctctgcag atgttgaaca tttgaagtca ttcctggatt cgtctactcc
     1801 atgtgagtcc cagcaaccca tggagcccat gagtagtcag gatgaccttg aaagcagtga
     1861 tccattttgc ggggagcacc aggaggcagc ctgtggatcc ctgaatacca ctccagaaag
     1921 tgggacacca ctgtcccgca agatgccact ttctatgtca aacaccacgg gcggccaaaa
     1981 gagaggagaa aaacaaggca gaaagaggaa gacagaacca tcctcctcca gcgcagaagt
     2041 gaacaaggac attcccaaag aaaatactcc tgaccaaaaa aagaaatcca ggcgatatta
     2101 ttccaggaac agaggcggca aagcagagaa agctgtgacc ttaagagaac aagaaaagcg
     2161 tagcaattgg aaacttgaac ctgctttcaa ttccaaatcc tatggaaggg ctaacctgga
     2221 tggcactatc cttccaatcg cgacatgctc tgatgacaga gatgtatcaa tatttggact
     2281 ggagatcata acacataatg gagtccaatc tcttcctgac ccttacctaa atcaactaaa
     2341 acgtgaaggc ttcccaaact tgggaaatac ttgttacatg aattccattt tgcaatctgt
     2401 ctttgggatt ccaacctttg caaaggactt actcactcaa ggcatcccat gggagaaagt
     2461 ctcctacgat gaccttatca tgcccttaag ccagctcctt gtcttgaaag acattcggga
     2521 tgtagagatc aagggggagt tactcaccag tgtaaagaag tccatttcca cagttgcaga
     2581 cacattctcg ggcaatgaac agaacgatgc ccatgagttt ttaagtctgt gtttagacca
     2641 gctgaaactg aacatggaaa aagtaaatgc catgtgggat actgagagga gaaacacatg
     2701 tgctgggtct gctggcacca aaaggtttgt ttgtcccgtt ggagctaatt ttgaatttga
     2761 gctgcatagc tccatcatct gtgaaggctg tggtgaggct actatcaaaa ccgaagtgag
     2821 taattacctc tccattgacc tgcaccatgg gacaaaaaca caccctctat caattcaaaa
     2881 gtcttttgat cttttcttta caccagaaaa aattgagcat aactgtgaga aatgtaagaa
     2941 caagaattct gttctcaagt acacattgag gagactcccc agggtcctca ttgttcatct
     3001 gaaacgctac caagttacca ctgacttgtt gccagtgaag agtgagcagc cagttgagat
     3061 ttctaagtat ttaaatatat cttcccactg ccatgaaaac aggaagctac catttccctt
     3121 ggctaataca tccccagatg tctctcaagg gatgatgcct gggatcttca accagtcaat
     3181 gttatctaag aaggtgattt cagaatcctg tgaccccatg gttctacagg ttggatccag
     3241 tgtggatgct gaaatacaaa gcttccagat aatgtatgag gatgaagatg caagtgagga
     3301 gcagcagcag agaggcctgg aaagtggctc catgctggag ccagaactag tgaagacaga
     3361 aaaccggata ctcagacaaa agacatcact agcaactgac tcaatgatgg gtgacggata
     3421 cagcttcctt cctatgctct gtgagcctct gagcatccaa gatccaggtc ttgcagagat
     3481 gggtcttcaa gaggttccag agaatccaga atttaagaac tatgagaaaa ttaacatata
     3541 tggaaagtca gatggccgca ctaacactga gttgtcaaaa ctctaccaga atcatggaag
     3601 tcgaatcaag ggtttgttcc taccggcatc ccttgcaagt gttagttctc aggaagaccc
     3661 agagaaggac ctgagtaggt ctccagaatt gcaggaagat gacccacatt cctttgcatt
     3721 tggttctgat gattccaaag atggggagat gggagatgat cttcagaatt acaggctcgt
     3781 cagtgtggtc agccactttg ggagctcccc aaattcaggc cattacgtaa gtgatgtgta
     3841 tgactttcaa aagcaagcct ggctccttta cagtgatgtc caagtgttcg agagttcaga
     3901 tccctccatt caggagaaca ggctaaacag cggatacatc ttcttttaca tgcataatga
     3961 gatttttgag gaactgttga aaaaggcatc tgagtgcaag gtccttagca catctaagga
     4021 ggaaaagagg gacatagatt acttctcaac attgcttaac ggccttacat acatcctgga
     4081 agaattctaa atcctgccta aaatgaagaa gagtcacata gctcaagatg aaaacttgac
     4141 ataaaacaac gaacggacat aaaacaacga acggacataa aacaacgaac ggacatatta
     4201 gaacagaaac acaggccttg ctgatgcagg ctatgcacca ttctttccta taaggctaaa
     4261 tggtgctttt cctgttttgt ggtggtttta atttattcac agatgttaag aaaactcatc
     4321 attttgagag taccatttgt taacgtaata gggatctgga gagatggtgg agtagttgag
     4381 agtgcaaact tctcccatag aggacccaag cttgacttcc caatacctgt gttaggtgtg
     4441 agcgcatgtg tccttggaga caggaggcat gggatcaccc ggaatgcgaa ttacaagtga
     4501 gagtgagctg cctggcttgg gtgctgggaa ctgaacttag gtcttctgca aggacagttt
     4561 ccacttttaa acactaagcc atctcttggc tttcattcta attttagtgt gtgtgctatc
     4621 cgtatgagca aagcatgatg ctttttaaac gttgttctga accaatacaa cacagcaagg
     4681 aaccaattac aagttcaaat gctggggttc aatgtcagaa acaataccag tagttactta
     4741 aaagtttgag aaacatttat ttagtgtgtg gagtgtccta ttaaatttta gtgtatatat
     4801 aaatcgctca tgtcatccag aggttcctca tttttttccc taaattcata tgtgttgttg
     4861 ttttgtcaat ttattaaaac cattgttttc catgtgtgtt tgtgattcat cgatgagatc
     4921 atatagttgc ccaccacctg gttttgtgct tctcagaatt acagggtaca ttaaagttac
     4981 acaggaaatg aaatagatag tatttgcaaa ttgaaaagca ctctaaggac tctgggtaaa
     5041 aacacctgcc accaagcccc atgacccaac tctaatgagt tgccctctga cctctaggga
     5101 agctatcaca tgaacaccca taaacagatg gatgaataaa atctaacttt ctaaaggttt
     5161 actcatttac tgtgtgtgtg tatatatata tatatatata tatattatat atagtgttct
     5221 gccttcttgt aggcctacac atcagaagag agcaccagat ctcattataa atgattgtga
     5281 gccaccatga ggctgttggg aattgagctc aggacttctg gaagaacagc cagtactctt
     5341 aacccctgag ccatctctct atcccctaaa atttgttttt tttttttttt tgaaatctca
     5401 ctatatggct ggcttgggac tttgtataga tcaggctacc cctaaactca agagatttgc
     5461 cctgcctctt gggtgctggt attgaagatc tgcaccacca tgcctaacac aatgagaatt
     5521 taaaagcact ttaaagtgcc aaatatactt gttaagattt aaatcaggat tgacatgaga
     5581 aaatggggtg gttcaaggta gaggataagt gttagactgt cctgcaggtg agagcttcgt
     5641 tagaaatagt aataccacaa acggcagagt gggattctaa agagagaacc ttcagctcag
     5701 aagagaaagc aaggttcccc ttaatttcca agagccccat gccataaagc agttaaagag
     5761 cagcgcatgc tttcccctgg ttctgggctg caaggggaag gcaacaataa gttggtgtca
     5821 ctgtctacat ggtgtgtagc ttgatctgag acaccaacac cacatctaat agtgattcaa
     5881 acatgaaaaa attagtcact ttcaagggtc tagggagata gttcagtagg taagggtcat
     5941 gtgcaagcat ggggacttga gttcaaatcc ccagcaccca cttaaggtgg tcatgggcat
     6001 agatggccat gactgtagca ttggacagca aaggcagatt ccagagctca ctagccaacc
     6061 agcagccaaa atggtaagag tatggctcag tgagattgta tttaaaaatg gaaagtggag
     6121 gaagacagca ctgggtgtct tctggctttc acatgtgcat gcatccgtgt gcaaaccatc
     6181 atacaagtgt tattccccaa attcctcttc gggcccggag aaatgattaa gattactttc
     6241 tcctctttca gaggccccag gttcaatccc tagtatccac atgggttcac accatctgta
     6301 ccttcagttc cagaggatca actggcctct tctggcttcg tagtacgcag acaaaacacc
     6361 tatatgtatt aaaaacattg cttcaatttt taccttcaaa ggggtaccat atattcatag
     6421 cctgtggcta gtcttaaaaa gcttataaca ttcacagtgt taatatacta tataagagca
     6481 tgtacaaaag tttagaacat tttgaggtta tgagaaaact actagttgga gagagagatg
     6541 ctcaggctta agagcactgg ctgctcgtcc agatgggccc aggttcagtt cccagcaccc
     6601 acacggcagc tcacaactct ctagaactct agttccacgt gatctgacac cctcacacag
     6661 acatgcacgc acgcaaaaca tcaatgcaca caaagtaaat gtatataaat tcgttaaaaa
     6721 gaaaacatct aatttgggtt ggtgaaatgg ctgagctgtt aagaactctg ggagcttttt
     6781 cagagttcct gagttcaatt cccagccact atatggtggc tcaggaccat ctatagaggg
     6841 atctgatgcc atcttctggt aagtaggtat acatgcagac agcactccta cactaaataa
     6901 ataaattaat taaatactaa aagcctggta atttataaaa tataaggcaa aattaagtga
     6961 gggtgattcg ggggaaaaga ttagtctagg acaggagttc tcaggttgtg ggttgctatc
     7021 cctttgggtg ggggttaaag gaccttttcg caggagatca catatgatag gcagtatgtt
     7081 gagagcaagc aaaagaaact tactttaaat acttccactt cattttcaga ctccattgaa
     7141 tcatagggag aaactaagtt caagctccca ggccgtaggg aagctgggga cttcccaaga
     7201 gctgagcagc ttctattatg gggaaacagt tgtctgagtt caaacagctc aagaacaact
     7261 ccatcttgct ggcagagtca tacatactaa gttcatgttc ccaggtccag gaacctactc
     7321 ctaacctgtt tggtgaaaac tcccttgctc agccccttgt gtcaaaatat ggtagagtaa
     7381 tgctacagcc taccccgtcc ccctcgagtt gtggtcttgt cctttaaata aatatgttgt
     7441 acaatttctc ttctggtcgc agttcagctt ctgagtctgt tctttggcta tgattgatca
     7501 gtagtggctt aattacaata aatgtttttc atctgcattg
//
