LOCUS       NM_001001559            1638 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus ubiquitin specific peptidase 17-like D (Usp17ld),
            mRNA.
ACCESSION   NM_001001559 XM_357799
VERSION     NM_001001559.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1638)
  AUTHORS   Gonzalez-Navajas,J.M., Law,J., Nguyen,K.P., Bhargava,M., Corr,M.P.,
            Varki,N., Eckmann,L., Hoffman,H.M., Lee,J. and Raz,E.
  TITLE     Interleukin 1 receptor signaling regulates DUBA expression and
            facilitates Toll-like receptor 9-driven antiinflammatory cytokine
            production
  JOURNAL   J Exp Med 207 (13), 2799-2807 (2010)
   PUBMED   21115691
  REMARK    GeneRIF: Data show that DUBA short interference RNA augmented the
            TLR9-dependent type I IFN response.
REFERENCE   2  (bases 1 to 1638)
  AUTHORS   Ramakrishna,S., Suresh,B., Kang,I.C. and Baek,K.H.
  TITLE     Polyclonal and monoclonal antibodies specific for USP17, a
            proapoptotic deubiquitinating enzyme
  JOURNAL   Hybridoma (Larchmt) 29 (4), 311-319 (2010)
   PUBMED   20715989
REFERENCE   3  (bases 1 to 1638)
  AUTHORS   Burrows,J.F., Scott,C.J. and Johnston,J.A.
  TITLE     The DUB/USP17 deubiquitinating enzymes: a gene family within a
            tandemly repeated sequence, is also embedded within the copy number
            variable beta-defensin cluster
  JOURNAL   BMC Genomics 11, 250 (2010)
   PUBMED   20403174
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1638)
  AUTHORS   Baek,K.H.
  TITLE     Cytokine-regulated protein degradation by the ubiquitination system
  JOURNAL   Curr Protein Pept Sci 7 (2), 171-177 (2006)
   PUBMED   16611142
  REMARK    Review article
REFERENCE   5  (bases 1 to 1638)
  AUTHORS   Burrows,J.F., McGrattan,M.J. and Johnston,J.A.
  TITLE     The DUB/USP17 deubiquitinating enzymes, a multigene family within a
            tandemly repeated sequence
  JOURNAL   Genomics 85 (4), 524-529 (2005)
   PUBMED   15780755
REFERENCE   6  (bases 1 to 1638)
  AUTHORS   Burrows,J.F., McGrattan,M.J., Rascle,A., Humbert,M., Baek,K.H. and
            Johnston,J.A.
  TITLE     DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks
            proliferation
  JOURNAL   J Biol Chem 279 (14), 13993-14000 (2004)
   PUBMED   14699124
REFERENCE   7  (bases 1 to 1638)
  AUTHORS   Baek,K.H., Kim,M.S., Kim,Y.S., Shin,J.M. and Choi,H.K.
  TITLE     DUB-1A, a novel deubiquitinating enzyme subfamily member, is
            polyubiquitinated and cytokine-inducible in B-lymphocytes
  JOURNAL   J Biol Chem 279 (4), 2368-2376 (2004)
   PUBMED   14583620
REFERENCE   8  (bases 1 to 1638)
  AUTHORS   Baek,K.H., Mondoux,M.A., Jaster,R., Fire-Levin,E. and D'Andrea,A.D.
  TITLE     DUB-2A, a new member of the DUB subfamily of hematopoietic
            deubiquitinating enzymes
  JOURNAL   Blood 98 (3), 636-642 (2001)
   PUBMED   11468161
REFERENCE   9  (bases 1 to 1638)
  AUTHORS   Zhu,Y., Lambert,K., Corless,C., Copeland,N.G., Gilbert,D.J.,
            Jenkins,N.A. and D'Andrea,A.D.
  TITLE     DUB-2 is a member of a novel family of cytokine-inducible
            deubiquitinating enzymes
  JOURNAL   J Biol Chem 272 (1), 51-57 (1997)
   PUBMED   8995226
REFERENCE   10 (bases 1 to 1638)
  AUTHORS   Zhu,Y., Pless,M., Inhorn,R., Mathey-Prevot,B. and D'Andrea,A.D.
  TITLE     The murine DUB-1 gene is specifically induced by the betac subunit
            of interleukin-3 receptor
  JOURNAL   Mol Cell Biol 16 (9), 4808-4817 (1996)
   PUBMED   8756639
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC108410.9.
            
            On Aug 23, 2006 this sequence version replaced NM_001001559.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF393638.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-28                AC108410.9         155343-155370
            29-1638             AC108410.9         156153-157762
FEATURES             Location/Qualifiers
     source          1..1638
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 54.85 cM"
     gene            1..1638
                     /gene="Usp17ld"
                     /gene_synonym="Dub2a; Dub4"
                     /note="ubiquitin specific peptidase 17-like D"
                     /db_xref="GeneID:384701"
                     /db_xref="MGI:MGI:3051372"
     CDS             1..1638
                     /gene="Usp17ld"
                     /gene_synonym="Dub2a; Dub4"
                     /EC_number="3.4.19.12"
                     /note="deubiquitinating enzyme 2a"
                     /codon_start=1
                     /product="ubiquitin carboxyl-terminal hydrolase 17-like
                     protein D"
                     /protein_id="NP_001001559.2"
                     /db_xref="CCDS:CCDS21567.1"
                     /db_xref="GeneID:384701"
                     /db_xref="MGI:MGI:3051372"
                     /translation="MVVSLSFPEADPALSSPGAQQLHQDEAQVVVELTANDKPSLSWE
                     CPQGPGCGLQNTGNSCYLNAALQCLTHTPPLADYMLSQEYSQTCCSPEGCKMCAMEAH
                     VTQSLLHSHSGDVMKPSQILTSAFHKHQQEDAHEFLMFTLETMHESCLQVHRQSEPTS
                     EDSSPIHDIFGGLWRSQIKCLHCQGTSDTYDRFLDVPLDISSAQSVNQALWDTEKSEE
                     LRGENAYYCGRCRQKMPASKTLHIHSAPKVLLLVLKRFSAFMGNKLDRKVSYPEFLDL
                     KPYLSQPTGGPLPYALYAVLVHEGATCHSGHYFSYVKAGHGKWYKMDDTKVTSCDVTS
                     VLNENAYVLFYVQQTDLKEVSIDMPEGRIHEVLDPEYQLKKSRRKKHKKKSPCTEDVG
                     EPSKNREKKATKETSLGEGKVLQEKNHKKAGQKHENTKLVPQEQNHQKLGQKHRNNEI
                     LPQEQNHQKTGQSLRNTEGELDLPADAIVIHLPRSIANWGRDTPDKVNQPWHNADRLL
                     TSQDLVNTGQLCRQEGRRRSKKGKNKNKQGQKLLLVR"
     exon            1..28
                     /gene="Usp17ld"
                     /gene_synonym="Dub2a; Dub4"
                     /inference="alignment:Splign:2.1.0"
     exon            29..1638
                     /gene="Usp17ld"
                     /gene_synonym="Dub2a; Dub4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggtggttt ctctttcctt cccagaagca gatccagccc tatcatctcc tggtgcccaa
       61 cagctgcatc aggatgaagc tcaggtagtg gtggagctaa ctgccaatga caagcccagt
      121 ctgagttggg aatgtcccca aggaccagga tgcgggcttc agaacacagg caacagctgc
      181 tacctgaatg cagccctgca gtgcttgaca cacacaccac ctctagctga ctacatgctg
      241 tcccaggagt acagtcaaac ctgttgttcc ccagaaggct gtaagatgtg tgctatggaa
      301 gcccatgtaa cccagagtct cctgcactct cactcggggg atgtcatgaa gccctcccag
      361 attttgacct ctgccttcca caagcaccag caggaagatg cccatgagtt tctcatgttc
      421 accttggaaa caatgcatga atcctgcctt caagtgcaca gacaatcaga acccacctct
      481 gaggacagct cacccattca tgacatattt ggaggcttgt ggaggtctca gatcaagtgt
      541 ctccattgcc agggtacctc agatacatat gatcgcttcc tggatgtccc cctggatatc
      601 agctcagctc agagtgtaaa tcaagccttg tgggatacag agaagtcaga agagctacgt
      661 ggagagaatg cctactactg tggtaggtgt agacagaaga tgccagcttc caagaccctg
      721 catattcata gtgccccaaa ggtactcctg ctagtgttaa agcgcttctc ggccttcatg
      781 ggtaacaagt tggacagaaa agtaagctac ccggagttcc ttgacctgaa gccatacctg
      841 tcccagccta ctggaggacc tttgccttat gccctctatg ctgtcctggt ccatgaaggt
      901 gcgacttgtc acagtggaca ttacttctct tatgtcaaag ctggacatgg gaagtggtac
      961 aagatggatg atactaaggt caccagctgc gatgtgactt ctgtcctgaa tgagaatgcc
     1021 tatgtgctct tctatgtgca gcagactgac ctcaaagagg tcagtattga catgccagag
     1081 ggcagaatac atgaggttct cgaccctgaa taccagctga agaaatcccg gagaaaaaag
     1141 cataagaaga aaagcccttg cacagaagat gtgggagagc cctccaaaaa cagggagaag
     1201 aaagcaacca aagaaacctc cttaggggag gggaaagtgc ttcaggaaaa gaaccacaag
     1261 aaagctgggc agaaacacga gaataccaaa ctcgtgcctc aggaacagaa ccaccagaaa
     1321 ctggggcaga aacacaggaa caatgaaatc ttgcctcagg aacagaacca ccagaaaact
     1381 gggcagagcc tcaggaacac ggaaggtgaa cttgatctgc ctgctgatgc aattgtgatt
     1441 cacctgccca gatccatagc aaattggggc agggatactc cagacaaggt gaatcaaccc
     1501 tggcacaatg ctgacaggct cctcacctct caggaccttg tgaacactgg gcagctctgt
     1561 agacaggaag gaagacgaag atcgaagaag gggaagaaca agaacaagca agggcagaag
     1621 cttctgcttg ttcgctag
//
