LOCUS       NM_010089               1697 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus ubiquitin specific peptidase 17-like C (Usp17lc),
            mRNA.
ACCESSION   NM_010089
VERSION     NM_010089.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1697)
  AUTHORS   Baek,K.H., Lee,H., Yang,S., Lim,S.B., Lee,W., Lee,J.E., Lim,J.J.,
            Jun,K., Lee,D.R. and Chung,Y.
  TITLE     Embryonic demise caused by targeted disruption of a cysteine
            protease Dub-2
  JOURNAL   PLoS One 7 (9), e44223 (2012)
   PUBMED   22984479
  REMARK    GeneRIF: The targeted disruption of Dub-2 may cause embryonic
            lethality during early gestation.
REFERENCE   2  (bases 1 to 1697)
  AUTHORS   Ramakrishna,S., Suresh,B., Kang,I.C. and Baek,K.H.
  TITLE     Polyclonal and monoclonal antibodies specific for USP17, a
            proapoptotic deubiquitinating enzyme
  JOURNAL   Hybridoma (Larchmt) 29 (4), 311-319 (2010)
   PUBMED   20715989
REFERENCE   3  (bases 1 to 1697)
  AUTHORS   Burrows,J.F., Scott,C.J. and Johnston,J.A.
  TITLE     The DUB/USP17 deubiquitinating enzymes: a gene family within a
            tandemly repeated sequence, is also embedded within the copy number
            variable beta-defensin cluster
  JOURNAL   BMC Genomics 11, 250 (2010)
   PUBMED   20403174
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1697)
  AUTHORS   Baek,K.H.
  TITLE     Cytokine-regulated protein degradation by the ubiquitination system
  JOURNAL   Curr Protein Pept Sci 7 (2), 171-177 (2006)
   PUBMED   16611142
  REMARK    Review article
REFERENCE   5  (bases 1 to 1697)
  AUTHORS   Burrows,J.F., McGrattan,M.J. and Johnston,J.A.
  TITLE     The DUB/USP17 deubiquitinating enzymes, a multigene family within a
            tandemly repeated sequence
  JOURNAL   Genomics 85 (4), 524-529 (2005)
   PUBMED   15780755
REFERENCE   6  (bases 1 to 1697)
  AUTHORS   Baek,K.H., Kim,M.S., Kim,Y.S., Shin,J.M. and Choi,H.K.
  TITLE     DUB-1A, a novel deubiquitinating enzyme subfamily member, is
            polyubiquitinated and cytokine-inducible in B-lymphocytes
  JOURNAL   J Biol Chem 279 (4), 2368-2376 (2004)
   PUBMED   14583620
REFERENCE   7  (bases 1 to 1697)
  AUTHORS   Baek,K.H.
  TITLE     Lymphocyte-specific murine deubiquitinating enzymes induced by
            cytokines
  JOURNAL   Am J Hematol 71 (4), 340-345 (2002)
   PUBMED   12447969
  REMARK    GeneRIF: induced by cytokines in lymphocytees [review]
            Review article
REFERENCE   8  (bases 1 to 1697)
  AUTHORS   Baek,K.H., Mondoux,M.A., Jaster,R., Fire-Levin,E. and D'Andrea,A.D.
  TITLE     DUB-2A, a new member of the DUB subfamily of hematopoietic
            deubiquitinating enzymes
  JOURNAL   Blood 98 (3), 636-642 (2001)
   PUBMED   11468161
REFERENCE   9  (bases 1 to 1697)
  AUTHORS   Zhu,Y., Lambert,K., Corless,C., Copeland,N.G., Gilbert,D.J.,
            Jenkins,N.A. and D'Andrea,A.D.
  TITLE     DUB-2 is a member of a novel family of cytokine-inducible
            deubiquitinating enzymes
  JOURNAL   J Biol Chem 272 (1), 51-57 (1997)
   PUBMED   8995226
REFERENCE   10 (bases 1 to 1697)
  AUTHORS   Zhu,Y., Pless,M., Inhorn,R., Mathey-Prevot,B. and D'Andrea,A.D.
  TITLE     The murine DUB-1 gene is specifically induced by the betac subunit
            of interleukin-3 receptor
  JOURNAL   Mol Cell Biol 16 (9), 4808-4817 (1996)
   PUBMED   8756639
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC162877.2.
            
            [WARNING] On Feb 7, 2025 this sequence was replaced by NM_010089.4.
            
            On Dec 27, 2006 this sequence version replaced NM_010089.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U70369.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-50                AC162877.2         80937-80986
            51-1697             AC162877.2         81769-83415
FEATURES             Location/Qualifiers
     source          1..1697
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 54.85 cM"
     gene            1..1697
                     /gene="Usp17lc"
                     /gene_synonym="Dub-2; Dub2; Dub2b; Usp17l5"
                     /note="ubiquitin specific peptidase 17-like C"
                     /db_xref="GeneID:13532"
                     /db_xref="MGI:MGI:107698"
     exon            1..50
                     /gene="Usp17lc"
                     /gene_synonym="Dub-2; Dub2; Dub2b; Usp17l5"
                     /inference="alignment:Splign:2.1.0"
     CDS             23..1660
                     /gene="Usp17lc"
                     /gene_synonym="Dub-2; Dub2; Dub2b; Usp17l5"
                     /EC_number="3.4.19.12"
                     /note="deubiquitinating enzyme 2; ubiquitin specific
                     peptidase 17-like 5"
                     /codon_start=1
                     /product="ubiquitin carboxyl-terminal hydrolase 17-like
                     protein C"
                     /protein_id="NP_034219.3"
                     /db_xref="CCDS:CCDS21572.1"
                     /db_xref="GeneID:13532"
                     /db_xref="MGI:MGI:107698"
                     /translation="MVVSLSFPEADPALSSPGAQQLHQDEAQVVVELTANDKPSLSWE
                     CPQGPGCGLQNTGNSCYLNAALQCLTHTPPLADYMLSQEYSQTCCSPEGCKMCAMEAH
                     VTQSLLHSHSGDVMKPSQILTSAFHKHQQEDAHEFLMFTLETMHESCLQVHRQSEPTS
                     EDSSPIHDIFGGLWRSQIKCLHCQGTSDTYDRFLDVPLDISSAQSVNQALWDTEKSEE
                     LRGENAYYCGRCRQKMPASKTLHIHSAPKVLLLVLKRFSAFMGNKLDRKVSYPEFLDL
                     KPYLSQPTGGPLPYALYAVLVHEGATCHSGHYFSYVKARHGAWYKMDDTKVTSCDVTS
                     VLNENAYVLFYVQQTDLKQVSIDMPEGRVHEVLDPEYQLKKSRRKKHKKKSPCTEDAG
                     EPCKNREKRATKETSLGEGKVLQEKNHKKAGQKHENTKLVPQEQNHQKLGQKHRINEI
                     LPQEQNHQKAGQSLRNTEGELDLPADAIVIHLLRSTENWGRDAPDKENQPWHNADRLL
                     TSQDPVNTGQLCRQEGRRRSKKGKNKNKQGQRLLLVC"
     exon            51..1697
                     /gene="Usp17lc"
                     /gene_synonym="Dub-2; Dub2; Dub2b; Usp17l5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atttgaagag gtctttggag acatggtggt ttctctttcc ttcccagaag cagatccagc
       61 cctatcatct cctggtgccc aacagctgca tcaggatgaa gctcaggtag tggtggagct
      121 aactgccaat gacaagccca gtctgagttg ggaatgtccc caaggaccag gatgcgggct
      181 tcagaacaca ggcaacagct gctacctgaa tgcagccctg cagtgcttga cacacacacc
      241 acctctagct gactacatgc tgtcccagga gtacagtcaa acctgttgtt ccccagaagg
      301 ctgtaagatg tgtgctatgg aagcccatgt aacccagagt ctcctgcact ctcactcggg
      361 ggatgtcatg aagccctccc agattttgac ctctgccttc cacaagcacc agcaggaaga
      421 tgcccatgag tttctcatgt tcaccttgga aacaatgcat gaatcctgcc ttcaagtgca
      481 cagacaatca gaacccacct ctgaggacag ctcacccatt catgacatat ttggaggctt
      541 gtggaggtct cagatcaagt gtctccattg ccagggtacc tcagatacat atgatcgctt
      601 cctggatgtc cccctggata tcagctcagc tcagagtgta aatcaagcct tgtgggatac
      661 agagaagtca gaagagctac gtggagagaa tgcctactac tgtggtaggt gtagacagaa
      721 gatgccagct tccaagaccc tgcatattca tagtgcccca aaggtactcc tgctagtgtt
      781 aaagcgcttc tcggccttca tgggtaacaa gttggacaga aaagtaagct acccagagtt
      841 ccttgacctg aagccatacc tgtcccagcc tactggagga cctttgcctt atgccctcta
      901 tgctgtcctg gtccatgaag gtgcgacttg tcacagtgga cattacttct cttatgtcaa
      961 agccagacat ggggcatggt acaagatgga tgatactaag gtcaccagct gcgatgtgac
     1021 ttctgtcctg aatgagaatg cctatgtgct cttctatgtg cagcagactg acctcaaaca
     1081 ggtcagtatt gacatgccag agggcagagt acatgaggtt ctcgaccctg aataccagct
     1141 gaagaaatcc cggagaaaaa agcataagaa gaaaagccct tgcacagaag atgcgggaga
     1201 gccctgcaaa aacagggaga agagagcaac caaagaaacc tccttagggg aggggaaagt
     1261 gcttcaggaa aagaaccaca agaaagctgg gcagaaacat gagaatacca aacttgtgcc
     1321 tcaggaacag aaccaccaga aacttgggca gaaacacagg atcaatgaaa tcttgcctca
     1381 ggaacagaac caccagaaag ctgggcagag cctcaggaac acggaaggtg aacttgatct
     1441 gcctgctgat gcaattgtga ttcacctgct cagatccaca gaaaactggg gcagggatgc
     1501 tccagacaag gagaatcaac cctggcacaa tgctgacagg ctcctcacct ctcaggaccc
     1561 tgtgaacact gggcagctct gtagacagga aggaagacga agatcaaaga aggggaagaa
     1621 caagaacaag caagggcaga ggcttctgct tgtttgctag tgttcactca cccactcaca
     1681 caggctcctg tggacac
//
