LOCUS       NM_201409               1541 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus ubiquitin specific peptidase 17-like B (Usp17lb),
            transcript variant 1, mRNA.
ACCESSION   NM_201409
VERSION     NM_201409.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1541)
  AUTHORS   Ramakrishna,S., Suresh,B., Kang,I.C. and Baek,K.H.
  TITLE     Polyclonal and monoclonal antibodies specific for USP17, a
            proapoptotic deubiquitinating enzyme
  JOURNAL   Hybridoma (Larchmt) 29 (4), 311-319 (2010)
   PUBMED   20715989
REFERENCE   2  (bases 1 to 1541)
  AUTHORS   Burrows,J.F., Scott,C.J. and Johnston,J.A.
  TITLE     The DUB/USP17 deubiquitinating enzymes: a gene family within a
            tandemly repeated sequence, is also embedded within the copy number
            variable beta-defensin cluster
  JOURNAL   BMC Genomics 11, 250 (2010)
   PUBMED   20403174
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1541)
  AUTHORS   Baek,K.H.
  TITLE     Cytokine-regulated protein degradation by the ubiquitination system
  JOURNAL   Curr Protein Pept Sci 7 (2), 171-177 (2006)
   PUBMED   16611142
  REMARK    Review article
REFERENCE   4  (bases 1 to 1541)
  AUTHORS   Burrows,J.F., McGrattan,M.J. and Johnston,J.A.
  TITLE     The DUB/USP17 deubiquitinating enzymes, a multigene family within a
            tandemly repeated sequence
  JOURNAL   Genomics 85 (4), 524-529 (2005)
   PUBMED   15780755
REFERENCE   5  (bases 1 to 1541)
  AUTHORS   Burrows,J.F., McGrattan,M.J., Rascle,A., Humbert,M., Baek,K.H. and
            Johnston,J.A.
  TITLE     DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks
            proliferation
  JOURNAL   J Biol Chem 279 (14), 13993-14000 (2004)
   PUBMED   14699124
REFERENCE   6  (bases 1 to 1541)
  AUTHORS   Baek,K.H., Kim,M.S., Kim,Y.S., Shin,J.M. and Choi,H.K.
  TITLE     DUB-1A, a novel deubiquitinating enzyme subfamily member, is
            polyubiquitinated and cytokine-inducible in B-lymphocytes
  JOURNAL   J Biol Chem 279 (4), 2368-2376 (2004)
   PUBMED   14583620
  REMARK    GeneRIF: DUB-1A has functional deubiquitinating activity and the
            5'-flanking sequence of Dub-1A has a functional enhancer
            domain.Dub-1A is expressed in B- and T-lymphocytes, brain, heart,
            liver, lung, kidney, ovary, and spleen
REFERENCE   7  (bases 1 to 1541)
  AUTHORS   Baek,K.H., Mondoux,M.A., Jaster,R., Fire-Levin,E. and D'Andrea,A.D.
  TITLE     DUB-2A, a new member of the DUB subfamily of hematopoietic
            deubiquitinating enzymes
  JOURNAL   Blood 98 (3), 636-642 (2001)
   PUBMED   11468161
REFERENCE   8  (bases 1 to 1541)
  AUTHORS   Zhu,Y., Lambert,K., Corless,C., Copeland,N.G., Gilbert,D.J.,
            Jenkins,N.A. and D'Andrea,A.D.
  TITLE     DUB-2 is a member of a novel family of cytokine-inducible
            deubiquitinating enzymes
  JOURNAL   J Biol Chem 272 (1), 51-57 (1997)
   PUBMED   8995226
REFERENCE   9  (bases 1 to 1541)
  AUTHORS   Zhu,Y., Pless,M., Inhorn,R., Mathey-Prevot,B. and D'Andrea,A.D.
  TITLE     The murine DUB-1 gene is specifically induced by the betac subunit
            of interleukin-3 receptor
  JOURNAL   Mol Cell Biol 16 (9), 4808-4817 (1996)
   PUBMED   8756639
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC110621.6.
            
            On Dec 13, 2017 this sequence version replaced NM_201409.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY257250.1, BY726474.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-107               AC110621.6         193562-193668       c
            108-1541            AC110621.6         191342-192775       c
FEATURES             Location/Qualifiers
     source          1..1541
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 55.69 cM"
     gene            1..1541
                     /gene="Usp17lb"
                     /gene_synonym="DUB-1A; Dub1a; USP17-B"
                     /note="ubiquitin specific peptidase 17-like B"
                     /db_xref="GeneID:381944"
                     /db_xref="MGI:MGI:3051498"
     exon            1..107
                     /gene="Usp17lb"
                     /gene_synonym="DUB-1A; Dub1a; USP17-B"
                     /inference="alignment:Splign:2.1.0"
     CDS             80..1486
                     /gene="Usp17lb"
                     /gene_synonym="DUB-1A; Dub1a; USP17-B"
                     /EC_number="3.4.19.12"
                     /note="isoform 1 is encoded by transcript variant 1;
                     deubiquitinating enzyme 1a; ubiquitin carboxyl-terminal
                     hydrolase 17-like protein B"
                     /codon_start=1
                     /product="ubiquitin carboxyl-terminal hydrolase 17-like
                     protein B isoform 1"
                     /protein_id="NP_958811.2"
                     /db_xref="CCDS:CCDS21628.1"
                     /db_xref="GeneID:381944"
                     /db_xref="MGI:MGI:3051498"
                     /translation="MVVALSFPEADPAMSPPSAPELHQDEAQVVEELAANGKHSLSWE
                     SPQGPGCGLQNTGNSCYLNAALQCLTHTPPLADYMLSQEHSQTCCSPEGCKMCAMEAH
                     VTQSLLHTHSGDVMKPSQNLTSAFHKRKQEDAHEFLMFTLETMHESCLQVHRQSEPTS
                     EDSSPIHDIFGGWWRSQIKCHHCQGTSYSYDPFLDIPLDISSVQSVKQALQDTEKAEE
                     LCGENSYYCGRCRQKKPASKTLKLYSAPKVLMLVLKRFSGSMGKKLDRKVSYPEFLDL
                     KPYLSQPTGGPLPYALYAVLVHEGATCHSGHYFCCVKAGHGKWYKMDDTKVTSCDVTS
                     VLNENAYVLFYVQQNDLKKGSINMPEGRIHEVLDAKYQLKKSGEKKHNKSPCTEDAGE
                     PCENREKRSSKETSLGEGKVLQEQDHQKAGQKQENTKLTPQEQNHEKGGQNLRNTEGE
                     LDRLSGAIVVYQPICTAN"
     exon            108..1541
                     /gene="Usp17lb"
                     /gene_synonym="DUB-1A; Dub1a; USP17-B"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agacattctc tggagagaaa gacttcctgc tgatccctta gaagactaca gcaagttatt
       61 tgaagaggtc tttgaagtca tggtggttgc tctctccttc ccagaagcag atccagccat
      121 gtcacctcct agtgccccag agctgcatca ggatgaagcc caggtggtag aggagctggc
      181 tgccaatgga aagcacagtc tgagttggga gagtccccaa ggaccaggat gcgggctcca
      241 gaacacaggc aacagctgct acctgaatgc agccctgcag tgcttgacac acacaccacc
      301 tctagctgac tacatgctgt cccaggagca cagtcaaacc tgttgttccc cagaaggctg
      361 taagatgtgt gctatggaag cccatgtgac ccagagtctc ctgcacaccc actcagggga
      421 tgttatgaag ccctcccaga atttgacctc tgccttccac aagcgcaagc aggaagatgc
      481 ccatgagttt ctcatgttca ccttggaaac aatgcatgaa tcctgccttc aagtgcacag
      541 acaatcagaa cccacctctg aggacagctc acccattcat gacatatttg gaggctggtg
      601 gaggtctcag atcaagtgtc accactgcca gggcacctca tattcctatg atcccttcct
      661 ggacatcccc ctggatatca gctcagttca gagtgtgaag caagccttgc aggatacaga
      721 gaaggcagaa gagctatgtg gggagaattc ctactactgt ggtaggtgta gacaaaagaa
      781 gccagcttcc aagaccctaa agctttatag tgccccaaag gtactcatgc tagtgttaaa
      841 gcgcttttcg ggctctatgg gtaaaaagtt ggacagaaaa gtaagctacc cagagttcct
      901 tgacctgaag ccatacctgt cccagcctac tggagggcct ttgccttatg ccctctatgc
      961 cgtcctggtc catgaaggtg caacttgtca cagtggacat tacttctgtt gtgtcaaagc
     1021 tggccatggg aagtggtaca agatggatga tactaaggtc accagctgtg atgtgacttc
     1081 tgtcctgaat gagaatgcct atgtgctctt ctatgtgcag cagaatgacc tcaaaaaggg
     1141 tagtatcaac atgccagagg gcagaataca tgaggttctt gatgccaaat accagctgaa
     1201 gaaatcaggg gaaaaaaagc ataataaaag cccttgcaca gaagatgcag gagagccctg
     1261 cgaaaacagg gagaagagat catccaaaga aacctcctta ggggagggga aagttcttca
     1321 ggaacaggac caccagaaag ctgggcagaa acaagagaat accaaactca cgcctcagga
     1381 acagaaccac gagaaaggtg ggcagaacct caggaatact gaaggtgaac ttgatcgact
     1441 cagtggtgca attgtggttt accaacctat atgcactgca aactgaggca gggatgcttc
     1501 agacaaggag aatcaaccct tgcacaatgc tgacaggctc c
//
