LOCUS       NM_007887               2661 bp    mRNA    linear   ROD 18-NOV-2024
DEFINITION  Mus musculus ubiquitin specific peptidase 17-like A (Usp17la),
            mRNA.
ACCESSION   NM_007887 XM_908214
VERSION     NM_007887.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2661)
  AUTHORS   Shi,F., Xu,Y., Zhang,S., Fu,Z., Yu,Q., Zhang,S., Sun,M., Zhao,X.
            and Feng,X.
  TITLE     Decabromodiphenyl ethane affects embryonic development by
            interfering with nuclear F-actin in zygotes and leads to cognitive
            and social disorders in offspring mice
  JOURNAL   FASEB J 36 (8), e22445 (2022)
   PUBMED   35816173
REFERENCE   2  (bases 1 to 2661)
  AUTHORS   Gomez-Redondo,I., Ramos-Ibeas,P., Pericuesta,E.,
            Fernandez-Gonzalez,R., Laguna-Barraza,R. and Gutierrez-Adan,A.
  TITLE     Minor Splicing Factors Zrsr1 and Zrsr2 Are Essential for Early
            Embryo Development and 2-Cell-Like Conversion
  JOURNAL   Int J Mol Sci 21 (11), 4115 (2020)
   PUBMED   32527007
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2661)
  AUTHORS   De Iaco,A., Verp,S., Offner,S., Grun,D. and Trono,D.
  TITLE     DUX is a non-essential synchronizer of zygotic genome activation
  JOURNAL   Development 147 (2) (2020)
   PUBMED   31806660
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2661)
  AUTHORS   Yang,J., Huang,X., Hu,F., Fu,X., Jiang,Z. and Chen,K.
  TITLE     LncRNA ANRIL knockdown relieves myocardial cell apoptosis in acute
            myocardial infarction by regulating IL-33/ST2
  JOURNAL   Cell Cycle 18 (23), 3393-3403 (2019)
   PUBMED   31674275
REFERENCE   5  (bases 1 to 2661)
  AUTHORS   Ramakrishna,S., Suresh,B., Kang,I.C. and Baek,K.H.
  TITLE     Polyclonal and monoclonal antibodies specific for USP17, a
            proapoptotic deubiquitinating enzyme
  JOURNAL   Hybridoma (Larchmt) 29 (4), 311-319 (2010)
   PUBMED   20715989
REFERENCE   6  (bases 1 to 2661)
  AUTHORS   Baek,K.H., Mondoux,M.A., Jaster,R., Fire-Levin,E. and D'Andrea,A.D.
  TITLE     DUB-2A, a new member of the DUB subfamily of hematopoietic
            deubiquitinating enzymes
  JOURNAL   Blood 98 (3), 636-642 (2001)
   PUBMED   11468161
REFERENCE   7  (bases 1 to 2661)
  AUTHORS   Jaster,R., Zhu,Y., Pless,M., Bhattacharya,S., Mathey-Prevot,B. and
            D'Andrea,A.D.
  TITLE     JAK2 is required for induction of the murine DUB-1 gene
  JOURNAL   Mol Cell Biol 17 (6), 3364-3372 (1997)
   PUBMED   9154835
REFERENCE   8  (bases 1 to 2661)
  AUTHORS   Zhu,Y., Lambert,K., Corless,C., Copeland,N.G., Gilbert,D.J.,
            Jenkins,N.A. and D'Andrea,A.D.
  TITLE     DUB-2 is a member of a novel family of cytokine-inducible
            deubiquitinating enzymes
  JOURNAL   J Biol Chem 272 (1), 51-57 (1997)
   PUBMED   8995226
REFERENCE   9  (bases 1 to 2661)
  AUTHORS   Zhu,Y., Pless,M., Inhorn,R., Mathey-Prevot,B. and D'Andrea,A.D.
  TITLE     The murine DUB-1 gene is specifically induced by the betac subunit
            of interleukin-3 receptor
  JOURNAL   Mol Cell Biol 16 (9), 4808-4817 (1996)
   PUBMED   8756639
REFERENCE   10 (bases 1 to 2661)
  AUTHORS   Zhu,Y., Carroll,M., Papa,F.R., Hochstrasser,M. and D'Andrea,A.D.
  TITLE     DUB-1, a deubiquitinating enzyme with growth-suppressing activity
  JOURNAL   Proc Natl Acad Sci U S A 93 (8), 3275-3279 (1996)
   PUBMED   8622927
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            U41636.1.
            
            On Jan 11, 2008 this sequence version replaced NM_007887.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U41636.1, BC140988.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2517              U41636.1           13-2529
            2518-2661           U41636.1           2531-2674
FEATURES             Location/Qualifiers
     source          1..2661
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 55.69 cM"
     gene            1..2661
                     /gene="Usp17la"
                     /gene_synonym="Dub1; USP17-A"
                     /note="ubiquitin specific peptidase 17-like A"
                     /db_xref="GeneID:13531"
                     /db_xref="MGI:MGI:107699"
     exon            1..93
                     /gene="Usp17la"
                     /gene_synonym="Dub1; USP17-A"
                     /inference="alignment:Splign:2.1.0"
     exon            94..199
                     /gene="Usp17la"
                     /gene_synonym="Dub1; USP17-A"
                     /inference="alignment:Splign:2.1.0"
     CDS             172..1752
                     /gene="Usp17la"
                     /gene_synonym="Dub1; USP17-A"
                     /EC_number="3.4.19.12"
                     /note="ubiquitin carboxyl-terminal hydrolase DUB-1;
                     ubiquitin thioesterase DUB-1;
                     ubiquitin-specific-processing protease DUB-1; ubiquitin
                     thiolesterase DUB-1; deubiquitinating enzyme 1"
                     /codon_start=1
                     /product="ubiquitin carboxyl-terminal hydrolase 17-like
                     protein A"
                     /protein_id="NP_031913.1"
                     /db_xref="CCDS:CCDS21629.1"
                     /db_xref="GeneID:13531"
                     /db_xref="MGI:MGI:107699"
                     /translation="MVVALSFPEADPALSSPDAPELHQDEAQVVEELTVNGKHSLSWE
                     SPQGPGCGLQNTGNSCYLNAALQCLTHTPPLADYMLSQEHSQTCCSPEGCKLCAMEAL
                     VTQSLLHSHSGDVMKPSHILTSAFHKHQQEDAHEFLMFTLETMHESCLQVHRQSKPTS
                     EDSSPIHDIFGGWWRSQIKCLLCQGTSDTYDRFLDIPLDISSAQSVKQALWDTEKSEE
                     LCGDNAYYCGKCRQKMPASKTLHVHIAPKVLMVVLNRFSAFTGNKLDRKVSYPEFLDL
                     KPYLSEPTGGPLPYALYAVLVHDGATSHSGHYFCCVKAGHGKWYKMDDTKVTRCDVTS
                     VLNENAYVLFYVQQANLKQVSIDMPEGRINEVLDPEYQLKKSRRKKHKKKSPFTEDLG
                     EPCENRDKRAIKETSLGKGKVLQEVNHKKAGQKHGNTKLMPQKQNHQKAGQNLRNTEV
                     ELDLPADAIVIHQPRSTANWGRDSPDKENQPLHNADRLLTSQGPVNTWQLCRQEGRRR
                     SKKGQNKNKQGQRLLLVC"
     exon            200..2649
                     /gene="Usp17la"
                     /gene_synonym="Dub1; USP17-A"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2628..2633
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Usp17la"
                     /gene_synonym="Dub1; USP17-A"
                     /note="hexamer: AATAAA"
     polyA_site      2649
                     /gene="Usp17la"
                     /gene_synonym="Dub1; USP17-A"
                     /note="major polyA site"
ORIGIN      
        1 aggaaaaact tccttctgct cccttagaag actccagcta gttatttgaa gaggtctttg
       61 tagacacggt ggttgctctt tcctcccaag aagagattct ctagaaggga aaaacttcct
      121 tctgctccct tagaagacta cagcaagttc tttgaagagg tctttggaga catggtggtt
      181 gctctttcct tcccagaagc agatccagcc ctatcatctc ctgatgcccc agagctgcat
      241 caggatgaag ctcaggtggt ggaggagcta actgtcaatg gaaagcacag tctgagttgg
      301 gagagtcccc aaggaccagg atgcgggctc cagaacacag gcaacagctg ctacctgaat
      361 gcagccctgc agtgcttgac acacacacca cctctagctg actacatgct gtcccaggag
      421 cacagtcaaa cctgttgttc cccagaaggc tgtaagttgt gtgctatgga agcccttgtg
      481 acccagagtc tcctgcactc tcactcgggg gatgtcatga agccctccca tattttgacc
      541 tctgccttcc acaagcacca gcaggaagat gcccacgagt ttctcatgtt caccttggaa
      601 acaatgcatg aatcctgcct tcaagtgcac agacaatcaa aacccacctc tgaggacagc
      661 tcacccattc atgacatatt tggaggctgg tggaggtctc agatcaagtg tctcctttgc
      721 cagggtacct cagataccta tgatcgcttc ctggacatcc ccctggatat cagctcagct
      781 cagagtgtaa agcaagcctt gtgggataca gagaagtcag aagagctatg tggagataat
      841 gcctactact gtggtaagtg tagacagaag atgccagctt ctaagaccct gcatgttcat
      901 attgctccaa aggtactcat ggtagtgtta aatcgcttct cagccttcac gggtaacaag
      961 ttagacagaa aagtaagtta cccggagttc cttgacctga agccatacct gtctgagcct
     1021 actggaggac ctttgcctta tgccctctat gccgtcctgg tccatgatgg tgcgacttct
     1081 cacagtggac attacttctg ttgtgtcaaa gctggtcatg ggaagtggta caagatggat
     1141 gatactaaag tcaccaggtg tgatgtgact tctgtcctga atgagaatgc ctatgtgctc
     1201 ttctatgtgc agcaggccaa cctcaaacag gtcagtattg acatgccaga gggaagaata
     1261 aatgaggttc ttgaccctga ataccagctg aagaaatcac ggagaaaaaa gcataagaag
     1321 aaaagccctt tcacagaaga tttaggagag ccctgcgaaa acagggataa gagagcaatt
     1381 aaagaaacct ccttaggaaa ggggaaagtg cttcaggaag tgaaccacaa gaaagctggg
     1441 cagaaacacg ggaataccaa actcatgcct cagaaacaga accaccagaa agctgggcag
     1501 aacctcagga atactgaagt tgaacttgat ctgcctgctg atgcaattgt gattcaccag
     1561 cccagatcca ctgcaaactg gggcagggat tctccagaca aggagaatca acccttgcac
     1621 aatgctgaca ggctcctcac ctctcagggc cctgtgaaca cttggcagct ctgtagacag
     1681 gaagggagac gaagatcgaa gaaggggcag aacaagaaca agcaagggca gaggcttctg
     1741 cttgtttgct agtgatcacc cacccactca cacaggctcc tgtggacaca ctgttgaccc
     1801 aaggtgcctg gaacaagagg tttggatctc tgtttcaggc agggacaatg cctcaccctt
     1861 cacgtggggt ccacctatcc tctgggccct tgcctgtttt tgctgactga ctctctgatt
     1921 gtttgaatgt ggaaaaaaag tgcccaggat gttggtacag gttaaagaca agaagctgga
     1981 cacccggagg aggtctgaat agcctctcct gcaactcatg gaatctgagc agcatagaga
     2041 ctaaatcacc acactggagc tttcttttct tttcttttct tttcttttct tttcttttct
     2101 tttcttttct cttctcttct cttctcttct cttctcttct cttctcttct cttctcttct
     2161 cttctcttct ctcctctcct ctcctctcct ctcctctcct ctcctctcct ctcctttcct
     2221 ttcctttcct ttcctttttt tttaaattta ttttttgtta ttagatattt tctttattta
     2281 catttcaaat gctatcccaa aagttcccta taccctcccc caactctgcc accctaccca
     2341 cccactccca cttcttggct ctggcatttc cctgtactgg ggcatataaa gtttgcaata
     2401 ccaaagggcc tctcttccca atgatggcca actaggtcac cttctgctac atatgcagct
     2461 agagacccta agaaaacaca ctggaactct tgaggtttgg agttttcgct caggcaacaa
     2521 gttgcttttc aactgccctt tctaacctct tacccagaaa atgtgtagtt caccctgtag
     2581 agatagatgc tcttattctt agtgtgtgat caacagttct ttggtcaaat aaattctgtt
     2641 acttcacaaa aaaaaaaaaa a
//
