LOCUS       NM_021408              15891 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus usherin (Ush2a), mRNA.
ACCESSION   NM_021408 XM_136513 XM_136514 XM_196227
VERSION     NM_021408.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 15891)
  AUTHORS   Crane,R., Tebbe,L., Mwoyosvi,M.L., Al-Ubaidi,M.R. and Naash,M.I.
  TITLE     Expression of the human usherin c.2299delG mutation leads to
            early-onset auditory loss and stereocilia disorganization
  JOURNAL   Commun Biol 6 (1), 933 (2023)
   PUBMED   37700068
  REMARK    GeneRIF: Expression of the human usherin c.2299delG mutation leads
            to early-onset auditory loss and stereocilia disorganization.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15891)
  AUTHORS   Guan,Y., Du,H.B., Yang,Z., Wang,Y.Z., Ren,R., Liu,W.W., Zhang,C.,
            Zhang,J.H., An,W.T., Li,N.N., Zeng,X.X., Li,J., Sun,Y.X.,
            Wang,Y.F., Yang,F., Yang,J., Xiong,W., Yu,X., Chai,R.J., Tu,X.M.,
            Sun,J.P. and Xu,Z.G.
  TITLE     Deafness-Associated ADGRV1 Mutation Impairs USH2A Stability through
            Improper Phosphorylation of WHRN and WDSUB1 Recruitment
  JOURNAL   Adv Sci (Weinh) 10 (16), e2205993 (2023)
   PUBMED   37066759
  REMARK    GeneRIF: Deafness-Associated ADGRV1 Mutation Impairs USH2A
            Stability through Improper Phosphorylation of WHRN and WDSUB1
            Recruitment.
REFERENCE   3  (bases 1 to 15891)
  AUTHORS   Mathur,P.D., Zou,J., Neiswanger,G., Zhu,D., Wang,Y.,
            Almishaal,A.A., Vashist,D., Hammond,H.K., Park,A.H. and Yang,J.
  TITLE     Adenylyl cyclase 6 plays a minor role in the mouse inner ear and
            retina
  JOURNAL   Sci Rep 13 (1), 7075 (2023)
   PUBMED   37127773
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 15891)
  AUTHORS   Tebbe,L., Mwoyosvi,M.L., Crane,R., Makia,M.S., Kakakhel,M.,
            Cosgrove,D., Al-Ubaidi,M.R. and Naash,M.I.
  TITLE     The usherin mutation c.2299delG leads to its mislocalization and
            disrupts interactions with whirlin and VLGR1
  JOURNAL   Nat Commun 14 (1), 972 (2023)
   PUBMED   36810733
  REMARK    GeneRIF: The usherin mutation c.2299delG leads to its
            mislocalization and disrupts interactions with whirlin and VLGR1.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 15891)
  AUTHORS   Perrino,P.A., Newbury,D.F. and Fitch,R.H.
  TITLE     Peripheral Anomalies in USH2A Cause Central Auditory Anomalies in a
            Mouse Model of Usher Syndrome and CAPD
  JOURNAL   Genes (Basel) 12 (2), 151 (2021)
   PUBMED   33498833
  REMARK    GeneRIF: Peripheral Anomalies in USH2A Cause Central Auditory
            Anomalies in a Mouse Model of Usher Syndrome and CAPD.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 15891)
  AUTHORS   Bhattacharya,G., Kalluri,R., Orten,D.J., Kimberling,W.J. and
            Cosgrove,D.
  TITLE     A domain-specific usherin/collagen IV interaction may be required
            for stable integration into the basement membrane superstructure
  JOURNAL   J Cell Sci 117 (Pt 2), 233-242 (2004)
   PUBMED   14676276
REFERENCE   7  (bases 1 to 15891)
  AUTHORS   Pearsall,N., Bhattacharya,G., Wisecarver,J., Adams,J., Cosgrove,D.
            and Kimberling,W.
  TITLE     Usherin expression is highly conserved in mouse and human tissues
  JOURNAL   Hear Res 174 (1-2), 55-63 (2002)
   PUBMED   12433396
  REMARK    GeneRIF: Conservation of usherin is seen at the nucleotide and
            amino acid level when comparing the mouse and human gene sequences.
REFERENCE   8  (bases 1 to 15891)
  AUTHORS   Huang,D., Eudy,J.D., Uzvolgyi,E., Davis,J.R., Talmadge,C.B.,
            Pretto,D., Weston,M.D., Lehman,J.E., Zhou,M., Seemayer,T.A.,
            Ahmad,I., Kimberling,W.J. and Sumegi,J.
  TITLE     Identification of the mouse and rat orthologs of the gene mutated
            in Usher syndrome type IIA and the cellular source of USH2A mRNA in
            retina, a target tissue of the disease
  JOURNAL   Genomics 80 (2), 195-203 (2002)
   PUBMED   12160733
  REMARK    GeneRIF: Expressed in the cells of the outer nuclear layer of the
            retina and in cochlea.
REFERENCE   9  (bases 1 to 15891)
  AUTHORS   Bhattacharya,G., Miller,C., Kimberling,W.J., Jablonski,M.M. and
            Cosgrove,D.
  TITLE     Localization and expression of usherin: a novel basement membrane
            protein defective in people with Usher's syndrome type IIa
  JOURNAL   Hear Res 163 (1-2), 1-11 (2002)
   PUBMED   11788194
REFERENCE   10 (bases 1 to 15891)
  AUTHORS   Danciger,J.S., Danciger,M., Nusinowitz,S., Rickabaugh,T. and
            Farber,D.B.
  TITLE     Genetic and physical maps of the mouse rd3 locus; exclusion of the
            ortholog of USH2A
  JOURNAL   Mamm Genome 10 (7), 657-661 (1999)
   PUBMED   10384036
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122122.14, AK020845.1, DQ073638.1, AC165230.12 and AC129312.6.
            
            On Apr 25, 2007 this sequence version replaced NM_021408.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DQ073638.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMN00849374,
                                           SAMN00849381 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-672               AC122122.14        56229-56900         c
            673-1210            AK020845.1         43-580
            1211-2027           DQ073638.1         1015-1831
            2028-2158           AC165230.12        50128-50258         c
            2159-15778          DQ073638.1         1963-15582
            15779-15891         AC129312.6         106344-106456
FEATURES             Location/Qualifiers
     source          1..15891
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 92.29 cM"
     gene            1..15891
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /note="usherin"
                     /db_xref="GeneID:22283"
                     /db_xref="MGI:MGI:1341292"
     exon            1..672
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     CDS             197..15778
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /note="usher syndrome type-2A protein homolog; usher
                     syndrome type IIa protein homolog; Usher syndrome 2A
                     (autosomal recessive, mild) homolog"
                     /codon_start=1
                     /product="usherin precursor"
                     /protein_id="NP_067383.3"
                     /db_xref="CCDS:CCDS15607.1"
                     /db_xref="GeneID:22283"
                     /db_xref="MGI:MGI:1341292"
                     /translation="MHYLALSPGFLCYTIKTLILAYLASVLVLAASQGVFPRLENVGA
                     FRKVSTVPTHATCGFPGPSTFCRSPVAAEHVQLCTERLCIQDCPYRSASPLYTALLEG
                     LRSCIPADDGDLHPYSRSSSVSFMFGSHQNCPSLRAPRLAAELTLAVWLKLEQGGTMC
                     VIEKTVDGQIVFKVTISEKETMFYYRTVNGLQPPIKVMTPGRILMKKWIHLTVQVHQT
                     AISFFVDGLEENSTAFDTRTLHDSVTDSVSSVIQVGQSLNGSEQFVGRMQDFRLYNVS
                     LTNREILEVFSGDFPHLHIQPHCRCPGSHPRVHPSVQQYCIPNGAGDTPEHRMSRLNP
                     EAHPLSFINDDDVATSWISHVFTNITQLYEGVAISIDLENGQYQVLKVITQFSSLQPV
                     AIRIQRKKADSSPWEDWQYFARNCSVWGMKDNEDLENPNSVNCLQLPDFIPFSHGNVT
                     FDLLTSGQKHRPGYNDFYNSSVLQEFMRATQIRLHFHGQYYPAGHTVDWRHQYYAVDE
                     IIVSGRCQCHGHAETCDRTRRPYRCLCSPHSFTEGPQCDRCSPLYNDKPFRSGDNVNA
                     FNCKPCQCHGHASSCHYDASVDPFPLEHNRGGGGVCDDCQHHTTGRHCESCQDYFYRP
                     VGADPAAPDACKLCDCNRAGTRNGSLHCDPIGGQCDCKRRVSGRQCLQCQDGFYDLQA
                     LDPDGCRPCNCNPSGTVDGDITCHQNSGQCSCKANVIGLRCNRCNFGFKFLQSFNGDG
                     CEPCQCNLHGSVNQLCDPLSGQCACKKEAKGLKCDSCRENFYGLPWSACEVCDCSKAG
                     SQPGTVCDTETGQCVCKPNVGGRQCSQCKAGYFNLYQNDSHLCLTCNCEKMGTVNGSL
                     RCDKSTGQCPCKLGVTGLRCHQCKPHRFNLTMDNPQGCQACDCDSLGTLPGSMCDPIS
                     GQCLCLPHRQGRRCEQCQPGFYSSPSNATGCLPCLCHTAGAVSHICNSVTGQCSCHDP
                     STTGRSCHQCQESYFRFDPLTGRCRPCHCHVAGASNGTCDAVTGQCFCKEFVTGSKCD
                     TCVPGASHLDVNNLLGCSKTPSQQPPPRGWVQSSSTINVSWSPPECPNAHWLTYTLFR
                     NGSEIYTTEDEHPYYTQYFLDTSLSPHTAYSYYIETSNVHSSTRSIPVIYETKPEVSE
                     GHLNLTHIIPVGSDSITLTWTGLSNSSDPVAKYVLSCTPVDSTEPCVSYEGPETSATI
                     WNLVPFTQYCFSVQGCTNESCFYSLPIIVTTAQAPPQTQGPPTVWKISPTELRIEWSP
                     PVDSNGIIISYELYMRRWLSTEESLVFESHGLVSSHSALQSVNPSKNLLQQPQASTFI
                     SGLEPHTEYAFRVLAVNMAGRVSSAWASERTGESVPVFMAPPSVSPLSPHSLSVSWEK
                     PAENFTRGEIIGYKISMVSEHFPLHDVPVMCSKMVHFAKSQDQSYIVRGLEPYRTYSF
                     TVSLCDSVGCVTSALGSGQTLAAAPAQLRPPMVTGVNSTTVHIRWLPPAGVNGPPPLY
                     HLERKKSSLPAATAAVTKGTRFVGHGYCRFPRTAHADFIGIKASFRTRVPEGLILLAL
                     SPGDQEEYFTLQLKNGRPYFLYNSQGTLVEVTPTDDPSQGYRDGEWHEIIAVRHQAFG
                     QITLDGQYTGSSSSLNGSSVTGGYTGLFVGGVPQGHSVLQKRLEIIQRGFVGCLKDVF
                     IMKGYSPSGTWLPLDWQSSEEQVNVHPSWEGCPTNLEEGVQFLGAGFLELPSDTFHAA
                     KDFEISLKFQTDQLNGLLLFIHNTEGPDFLAVELKRGLLSFKFNSSLVFTRVDLRLGL
                     ADCDGKWNTVSIKKEGSVVSVRVNALKKSTSQAGGQPLLVNSPVYLGGIPRELQDAYR
                     HLTLEPGFRGCVKEVAFARGVVVNLASVSSRAVRVNQDGCLSSDSTVNCGGNDSILVY
                     RGSQQSVYESGLQPFTEYLYRVTASHEGGAVSSDWSRGRTLGTAPQSVPTPSRAQSIN
                     GSSVEVAWNEPAVVKGVLEKYVLKAYSEDSSQPRVPSASTELHDTSTHSGVLIGLHPF
                     HSYTVTLTACSRAGCTESSQALSISTPQEAPQEVQAPVAVALPNSLSFFWSLPRQANG
                     IITQYSLYVDGRLVYTGKGQNYTVTDLRVFAAYEIIVGACTQAGCTNSSQVILHTAQL
                     PPEQVDPPGLTVLDSRTIHVRWKQPRQLNGILERYILYILNPIHNSTMWSVVYNSTEK
                     LQAHVLHHLSPGGLYLIRLRVCTGGGCTTSEPSQALMEETIPEGVPAPRAHSYSPDSF
                     NISWTEPEYPNGVITTYELYLDDTLIHNSSGLSCHAYGFDPGSLHTFQVQACTAKGCA
                     LGPLVGNRTLEAPPEGVVNVLVKPEGSREAHVRWDAPAHPNGRLTYSVHFTGSFYADQ
                     AGDNYTLLSGTKTIRGIEGSRLWVLVDGLVPCSHYMVQVNASNSRGSVLSDPVSVEMP
                     PGAPDGLLSPRLAAAAPTSLQVVWSTPARNNAPGSPRYQLQMRPGPSTHGRLELFPIP
                     SASLSYEVTGLQPFTVYEFRLVATNGFGTAYSAWTPLMTTEDKPGPIDAPILINVKAR
                     MLSVIWRQPAKCNGAITHYNIYLHGRLYLTVSGRVTNYTVVPLHPYKAYHFQVEACTS
                     QGCSKSPSSETVWTLPGNPEGIPSPQLFPYTPTSIIVTWQPSAHLDLLVENVTIERRV
                     KGKKEVRNLVTLARSQAMKFIDNDPALRPWTRYEYRVLGSTLDGGTNSSAWVEVTTRP
                     CRPSGVQPPTVRVLAPDTVEVSWKAPLMQNGDILSYEIRMPEPLIKMTNMSSIMLSHL
                     VKHLIPFTNYSVTIVACSGGNGYLAGCTESPPTLATTHPAPPQELAPLSVILLSESDV
                     GISWQPPSKPNGPNLRYELLRCKIQQPLASNPPEDLNLWHNIYSGTRWFYKDKGLSRF
                     TTYEYKLFVHNSVGFTPSREVTVTTLAGSPERGATVTASILNHTAIDVRWKKPTFQDL
                     QGDVEYYTLFWSSGTSEESLKIFPDVDFHVIGQLSPNVEYQVFLLVFNGVHAINSTVV
                     HVTMWEEEPQGMLPPEVVIINSTAVRVIWTSPSNPNAVVTESSVYVNNKLYKTGTDAP
                     GSFVLEDLSPFTIYDIQVEVCTKDACVKSNGTQVSTAEDTPSDISIPVIRGITSRSLQ
                     IDWTTPANPNGIILGYDVLRKTWRPCSETQKLTDKPRDELCKAVKCQYPGKVCGHTCY
                     SPGTKVCCDGLLYDPQPGYSCCEDKYIALSPNATGVCCGGRMWEAQPDHQCCSGHYAR
                     ILPGEICCPDERHNRVSVGFGDACCGTMPYATSGSQVCCAGRLQDGYRQQCCGGEMVS
                     QDFQCCGGGEEGMVYSYLPGMLCCGQDYVNMSETICCSASSGESKAHVRKDDPTPVKC
                     CGTELSPESQRCCDGVGYNPLKYVCSDEISAGMAMKETRVCATICPATMKATAHCGRC
                     DFNATTHICTVMRGPLNPTGKKAVEGLCSAAEEIVHSGDVNTHSFIDRDLKPSTVYEY
                     RISAWNSYGRGFSQSVRASTREDVPEGVKAPRWARTGKHEDVIFLQWEEPMQSNGPII
                     HYILFRDGRERFQGTALSFTDTQGIQPLQEYSYQLKACTAAGCAVSCKVVAATTQRSP
                     ENVPPPNITAQSSETLHLSWSVPEKMKDAIKAYQLWLDGKGLIYTDTSDRRQHTVTGL
                     QPYTNYSFTLAVCTSVGCTSSEPCVGQTLQAAPQGVWVTPRHIIINSTTVELYWNPPE
                     RPNGLISQYQLRRNGSLLLVGGRDNQSFTDSNLEPGSRYIYKLEARTGGGSSWSEDYL
                     VQMPLWTPEDIHPPCNVTVLGSDSIFVAWPTPGNLLPKIPVEYSILLSGGSVTLLVFS
                     VRHRQSAHLKNLSPFTQYEIRIQACQNGGCGVSPGTYVRTLEAAPVGLMPPLLKALGS
                     SCIEVKWMPPTRPNGIITSYVVHRRPADTEEESLLFVWSEGALEFTDDTGTLRPFTLY
                     EYRVRAWNSQGAVDSPWSTIQTLEAPPRGLPAPRVQATSAHSAMLNWTEPEAPNGLIS
                     QYHVIYQERPDAAAPGSSTVHAFTVTGTSRQAHLFGLEPFTTYHIGVVAVNSAGKVSS
                     PWTLIKTLESAPSGLMNFTVEQREKGRALLLQWSEPVKTNGVIKAYNIFNDGVLEYSG
                     LGRQFLFRRLAPFTLYTLILEACTTAGCAHSVPQPLWTEEAPPDTQMAPTIQSVGPTN
                     VRLHWSQPASPNGKIIHYEVIRRRSEEEDWGNTTWQADGNTVFTEYNTQGNAWVYNDT
                     GLQPWRQYAYRICAWNSAGHTCSSWNVVRTLQAPPDGLSPPEISYVSMSPLQLLISWL
                     PPRHSNGVIQGYRLQRDGVLPALNFNASTFSYMDSQLLPFSTYSYAILACTGGGCCTS
                     EPTNITTPEVPPSEVSPPVLWDISAHQMNVSWSPPSIPNGKIVKYLLQCDGEEHLAGQ
                     GLSFLLSNLQPSTQYNISLVACTSGGCTASRTTSAWTKEAPPENMDPPTLHITGPESI
                     EITWTPPRNPHGLIRSYELRRDGAIVYVGLETRYHDFTLAPGVEYSYSVTATNSRGSV
                     LSPLVKGQTSPSAPSGLQPPKLHSGDALELLADWDPPVRTNGKIINYTLFVREMFEGK
                     TRAMSINTTHSSFGTRSLTVKHLKPFHRYEVRVQACTALGCTSSEWTSTQTSEVPPLR
                     QPAPHLEVQTATGGFQPIVAVWWAGPLQPNGKIICFELYRRQVAAWPGTSSSLLIYNG
                     SFRSFMDSELLPFTEYEYQVWAVNSAGKAASNWTRCRTGPAPPEGLQAPTFHTVSSTR
                     AVVNISVPSRPNGNISLFRVFSNSSGTHVTLSEGTATQQTLHDLSPFTTYTIGVEACT
                     CFNCCSRGPTAELRTHPAPPSGLSPPQVQTLGSRMASVHWTPPLLPNGVIHSYELQLQ
                     RACPPDSAPRCPPSHTERKYWGPGHRASLAGLQPNTAYGVQVVAYNEAGSTASGWTNF
                     STKKEMPQYQALFSVDSNASMVWVDWSGTFLLNGHLKEYVVTDGGRRVYSGLDTTLYI
                     PRMVDKIFFFQVTCTTDIGSVKTPLVQYDAATGSGLVLTTPGEKKGAGTKSTEFYSEL
                     WFIMVMAVVGLILLAIFLSLILQRKIHKEPCIRERPPLVPLQKRMTPLSVYPPGETHV
                     GLADTRLPRSGTPMSIRSSQSVSVLRIPSQSQLSHAYSQSSLHRSVSQLMDMADKKVV
                     TEDSLWETIMGHSSGLYVDEEELMNAIKGFSSVTKEHTAFTDTHL"
     exon            673..838
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            839..971
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            972..1035
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            1036..1330
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            1331..1515
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            1516..1737
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            1738..1831
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            1832..2027
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            2028..2158
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            2159..2354
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            2355..2996
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            2997..3180
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            3181..3344
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            3345..3503
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            3504..3998
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            3999..4259
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            4260..4429
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            4430..4574
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            4575..4796
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            4797..4927
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            4928..5054
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            5055..5156
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            5157..5336
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            5337..5467
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            5468..5741
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            5742..5945
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            5946..6026
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            6027..6218
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            6219..6332
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            6333..6494
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            6495..6654
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            6655..6826
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            6827..6974
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            6975..7126
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            7127..7289
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            7290..7469
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            7470..7620
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            7621..7763
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            7764..8392
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            8393..8727
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            8728..8850
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            8851..9014
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            9015..9224
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            9225..9427
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            9428..9540
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            9541..9739
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            9740..9908
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            9909..10130
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            10131..10354
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            10355..10559
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            10560..10757
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            10758..10912
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            10913..11111
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            11112..11219
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            11220..11403
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            11404..11561
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            11562..11720
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            11721..11883
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            11884..12238
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            12239..12466
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            12467..13983
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            13984..14305
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            14306..14512
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            14513..14751
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            14752..14960
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            14961..15137
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            15138..15221
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            15222..15466
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            15467..15688
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     exon            15689..15891
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /inference="alignment:Splign:2.1.0"
     regulatory      15778..15783
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /note="hexamer: AATAAA"
     polyA_site      15804
                     /gene="Ush2a"
                     /gene_synonym="A930011D15Rik; A930037M10Rik; Gm676; Gm983;
                     Mush2a; Ushrn"
                     /note="major polyA site"
ORIGIN      
        1 gcaccggctt cgactcatgt ttctgtcctc cctcaggaca cccttgctct gccttccctg
       61 tgacagtgtg tctacagtct ccccaagatg aaacatctca gggatcaagt gcctttccag
      121 gatttctggt gaacagtgca gccctggatc ttaatttagg aatgcttcat tgggtgaaga
      181 atcctttttt gtaatcatgc attacctggc tctctcaccg ggcttcctgt gttacaccat
      241 taaaacattg atccttgcct atttggcttc ggtattggtg ttggctgcct cacagggcgt
      301 tttcccaagg ctggagaatg tgggtgcttt caggaaggta tccactgtgc caacccacgc
      361 cacgtgtgga ttcccaggcc ctagcacttt ttgtcgtagc ccggtggcgg ctgagcatgt
      421 gcaactgtgt acggagaggc tgtgtatcca ggattgcccc taccgctctg cctctcctct
      481 ctatactgcc ctcctagaag gcctccggag ctgcatccct gcagacgacg gtgatctcca
      541 cccttactcc aggagcagct ccgtgagctt catgttcgga agtcaccaga actgcccgtc
      601 tctacgggct ccgaggctgg cagccgaatt gaccttagct gtgtggttga agcttgagca
      661 aggaggcact atgtgtgtga tagaaaagac agtggacggg cagattgtgt tcaaagttac
      721 aatatctgag aaagagacca tgttttatta tcgcacagta aatggtttgc agcctccaat
      781 aaaagtaatg acaccaggga gaattcttat gaagaaatgg attcatctca ctgtgcaggt
      841 gcatcagacg gcaatcagct tctttgtgga cggtctggag gagaacagta ctgcatttga
      901 tacaagaact ctccatgatt cagtcacaga ctcagtctcc agcgtgatac aagtaggaca
      961 gagtttaaat ggttcagagc agtttgttgg aagaatgcaa gattttcgat tgtacaatgt
     1021 gtcacttaca aacagggaga ttctagaggt cttttctgga gattttcctc acttgcacat
     1081 ccagccacat tgccgatgtc caggtagcca cccccgtgtc cacccctccg ttcagcagta
     1141 ctgcattccc aatggtgcag gagacacgcc cgagcatcga atgtcacggc tgaatcccga
     1201 agcccaccct ctctccttca tcaatgatga cgacgttgct acttcatgga tctctcatgt
     1261 gtttacaaac attacgcagc tctatgaagg agtggctatt tctatagact tagaaaatgg
     1321 acagtaccag gtgcttaaag tcatcaccca gttctccagc ctacagcctg tggcaattcg
     1381 gatccagagg aagaaggcag acagctctcc ctgggaggac tggcagtatt ttgccagaaa
     1441 ttgcagtgtt tggggaatga aggacaatga agatttggaa aatcccaatt ctgtcaactg
     1501 tctccagctt cctgatttta tcccgttttc ccatggtaat gtcacctttg acctcctgac
     1561 atctggacag aagcatcgtc ctgggtacaa cgacttttac aacagctcag tgcttcaaga
     1621 attcatgaga gccactcaaa taaggctgca cttccatggg cagtactatc cggctggaca
     1681 cactgttgac tggagacacc aatactatgc agtggatgag atcattgtca gtggaagatg
     1741 ccaatgccac ggccatgctg agacctgtga caggaccaga cggccttaca gatgtctctg
     1801 ctctccacac agcttcactg aagggcctca gtgtgatcga tgctcccctc tttataatga
     1861 caagcctttc cgcagtggtg acaatgttaa tgcattcaac tgtaagcctt gccagtgcca
     1921 tggccatgcc agcagctgcc actacgatgc ttctgtggac ccatttcccc tggaacacaa
     1981 cagaggcggt ggaggagtct gtgatgactg tcagcatcat acaacaggga gacactgtga
     2041 gtcgtgccag gattactttt accgacctgt tggtgctgat cctgctgccc cggatgcttg
     2101 caagctctgt gactgtaaca gggccgggac tagaaatggc agcctccact gtgacccgat
     2161 tggaggccaa tgtgattgta agagacgtgt gtctggcaga cagtgccttc agtgccagga
     2221 tggattctat gacctgcagg cgctagatcc tgacggctgc cgtccctgta actgtaatcc
     2281 ctctgggacc gtggatggag acattacctg tcaccaaaat tcaggccagt gctcgtgcaa
     2341 agcgaatgtt attgggctta gatgcaatcg ctgcaatttc ggatttaaat tcctccagag
     2401 ttttaatggt gatggatgtg agccttgcca atgtaacctc cacggctcag tgaaccaact
     2461 ctgtgatccg ctttctgggc agtgtgcatg caagaaggaa gccaaaggac ttaagtgtga
     2521 ctcttgcaga gaaaactttt atgggttgcc ctggagtgct tgtgaggtct gtgactgcag
     2581 caaggctggg tcccagcctg ggactgtctg tgacactgag acagggcagt gcgtttgtaa
     2641 gcccaatgtt ggagggagac aatgtagtca gtgtaaggca ggctacttca acctatatca
     2701 gaatgattcc cacctctgtt tgacttgtaa ctgcgagaag atgggaacgg taaatggctc
     2761 tctaaggtgt gacaagtcaa ccgggcagtg tccttgcaaa ctaggggtaa ctggtctgcg
     2821 ttgccaccag tgcaagcctc acaggttcaa tttgacgatg gacaatcctc aaggttgtca
     2881 ggcgtgcgac tgtgactcgt tggggacatt acctggaagc atgtgtgacc ccatcagtgg
     2941 ccagtgtcta tgtctacctc atcgacaagg aagaaggtgt gagcagtgtc agccaggctt
     3001 ttacagttct cccagcaatg ccactggctg cctgccatgc ttatgccaca cagctggtgc
     3061 tgtgagccac atctgtaata gtgtcacggg acagtgctct tgccatgacc cctcaaccac
     3121 tgggcgtagc tgtcaccagt gtcaagaaag ttactttaga tttgatcccc tgactggaag
     3181 atgcaggcct tgtcactgtc atgtagcagg agcctcgaat ggaacttgtg atgcagtcac
     3241 aggccagtgt ttctgcaaag agtttgtcac tggctcaaaa tgtgacactt gtgttcctgg
     3301 tgcaagccac ttggacgtca acaatctatt aggctgcagc aaaactccat ctcagcaacc
     3361 tccacccaga ggatgggttc agagttcttc taccatcaat gtgtcctgga gtccacccga
     3421 gtgcccaaat gctcactggc ttacatacac tctgttcagg aatggctctg agatctacac
     3481 aactgaagat gaacacccgt actatactca gtacttctta gacactagtc tgtcaccaca
     3541 cacagcatat tcatattata tagagacctc caatgtgcac agttcgacaa ggagcatacc
     3601 tgtcatttat gagacaaagc cagaggtctc agaaggacac ttgaacttga ctcacatcat
     3661 tcctgtgggc tcggactcca ttacacttac ctggactgga ctctccaaca gctctgatcc
     3721 tgtggcaaaa tatgttttat catgcacacc tgtggacagc actgagccct gtgtctccta
     3781 tgaaggtcca gaaacctcag ctaccatctg gaatctggtt ccattcaccc agtactgttt
     3841 ttctgtccag ggctgtacta atgagagctg tttctacagc ttgcctatta tagtaaccac
     3901 agcccaagca cctcctcaaa cgcaggggcc acctacagta tggaaaatca gtcccacaga
     3961 actcagaata gaatggtctc ctccagtgga ctcaaatggt ataattataa gctatgagtt
     4021 atacatgagg agatggctgt ccaccgaaga aagcctagtg tttgagagcc acggtttggt
     4081 cagttctcac tcagctttac agtcggtcaa tccgagtaag aacctgctcc agcagcccca
     4141 agccagcacg ttcatctctg gcttggagcc acacacagag tatgcattta gggtcttggc
     4201 tgtgaatatg gctggcaggg tgtcgtctgc ctgggcctca gaaagaacgg gggaatcagt
     4261 acccgtattc atggcccctc cttcagtctc tccactctca ccacactccc tcagtgtctc
     4321 ctgggagaag ccagcagaaa actttacaag aggagaaatt atagggtaca agatcagcat
     4381 ggtttctgaa catttccctc tacacgatgt tccagtcatg tgctcaaaga tggtgcattt
     4441 tgctaagtcc caagaccagt cttacatcgt aaggggactc gagccttata ggacctacag
     4501 cttcacagtg tccctctgcg attccgtggg ctgtgtaacc agtgctttgg gatcaggaca
     4561 aaccttagca gcagctcctg ctcagctccg gcctcccatg gtgacaggag tcaacagtac
     4621 tacagtccat atcaggtggc ttcctcctgc aggagtcaat ggaccacctc ctttgtacca
     4681 tctagaaagg aagaagtctt ccctcccagc tgccacagct gctgtgacaa agggaacccg
     4741 cttcgtggga cacggttact gcaggtttcc cagaacagct cacgcagatt ttataggaat
     4801 caaggccagc ttccggacaa gggtgcctga agggctgatc ctcctggcac tgtcccctgg
     4861 cgaccaggaa gagtatttca ccctgcagtt gaagaatggc cgtccttact ttctttacaa
     4921 ttcccaggga acactagtgg aagttacccc aactgatgat cctagtcaag gatacaggga
     4981 tggagagtgg catgaaatca tagcagtcag acatcaggct tttggccaga ttactcttga
     5041 tggacagtac acaggctcct cttcttctct gaatggaagc tccgtgacag gaggctacac
     5101 tggactgttt gtgggtggag tgccacaagg tcatagcgtc ctccagaaga ggcttgagat
     5161 aatccaaaga ggttttgtgg gctgcctcaa ggatgtgttc atcatgaagg gttacagccc
     5221 ctctgggacg tggctacctt tggattggca gagctctgag gagcaggtga atgttcatcc
     5281 cagctgggaa ggttgtccca ccaacctaga agaaggagtt cagttcctag gagcaggatt
     5341 tctggagctt ccttcagata cgtttcatgc tgcaaaggac tttgagatct ccctgaagtt
     5401 tcaaacagac caactaaatg gattgcttct tttcattcac aatacagagg gaccggattt
     5461 tcttgcggtg gagctgaaga gagggctgct gagcttcaag ttcaattcca gtctcgtctt
     5521 tacacgcgtg gatctcaggc tggggctggc cgattgtgat ggaaagtgga atacagtcag
     5581 tatcaaaaag gaaggctctg tggtatctgt ccgtgtgaat gcacttaaga agagcacctc
     5641 ccaggctgga ggccagcctc tgctggtgaa ttctcctgtc tatctgggcg ggatcccacg
     5701 ggagctgcag gacgcctaca gacatttgac tctggagcca gggttccgtg gttgcgtgaa
     5761 ggaagttgca tttgcacggg gtgttgtcgt taacttggca tctgtgtcca gccgtgctgt
     5821 cagagtcaat caggatggat gcctatcaag tgacagtact gttaactgtg ggggaaatga
     5881 ctccatcctg gtttatcggg gaagccagca gagtgtttat gagagcggtc tccagccctt
     5941 tacagaatac ctgtatcggg tcacagcctc acacgaagga ggagcggtgt ccagtgattg
     6001 gagtcgggga cgcacattgg gcacagctcc gcagagtgtg ccaactccct caagagccca
     6061 gagcataaac ggatccagcg ttgaggtggc ctggaatgag cctgctgtgg ttaaaggtgt
     6121 cctggagaag tacgttctga aagcctacag tgaggacagc tcccagcccc gcgtgccctc
     6181 tgccagcact gagcttcatg acaccagcac ccactcaggc gtgttgatag gacttcatcc
     6241 cttccacagc tacacggtaa ccctgactgc ttgttctcgg gcaggctgca ccgagagctc
     6301 acaggcattg agcatctcca ctccacaaga agcgccccag gaggtgcagg caccagtcgc
     6361 cgtggccctt cccaactcct tgtcattctt ttggagtcta cccagacaag caaatgggat
     6421 tattacgcag tactccttat acgtggatgg gaggctggtc tacacaggca agggacagaa
     6481 ctacacagtc acagatttaa gagtattcgc agcctacgag attatagttg gtgcatgcac
     6541 acaagcaggg tgcacaaaca gctcccaagt catcttgcac acagcacagc tgccgccaga
     6601 gcaagtggat cccccgggtt tgactgtcct ggattctagg actatccatg tacggtggaa
     6661 acaaccaagg caactaaatg gaattctgga gcgctacata ttatatattt tgaatcctat
     6721 acataactcc acaatgtgga gtgttgtcta taacagcaca gaaaaactcc aggctcacgt
     6781 gctccaccac ctttcccctg ggggtctata cctcatcagg ctgagagtgt gtaccggtgg
     6841 gggctgcaca acaagtgagc ccagccaggc cctaatggag gagacgattc cagaaggtgt
     6901 gccagccccc agagctcact cctactcacc agactccttt aacatctcct ggacagagcc
     6961 tgagtatccg aatggagtga tcaccacata tgagttatat ctagatgaca ctctgattca
     7021 caattcatca ggactcagct gccatgccta tggatttgat cctgggagct tacacacctt
     7081 ccaagttcaa gcatgcacgg caaagggttg tgctctgggc ccactggtag gaaaccggac
     7141 tctagaagct cctccggaag gcgtggtcaa cgtgcttgtc aaacctgagg gatcccggga
     7201 agcccacgtg aggtgggatg cgcctgcgca ccctaacggg cgcttaacct actcagtcca
     7261 tttcaccgga agtttctatg cagatcaagc aggtgacaac tacacccttc tcagtggtac
     7321 aaaaactatc cgcggcatcg aaggaagccg gctctgggtg ctggtggacg gactggttcc
     7381 ttgctcacac tacatggtac aagtgaatgc ttctaacagc agagggagcg tgctcagtga
     7441 ccctgtttcc gttgaaatgc ctcccggggc tccagatggc ctgctgtctc ccaggcttgc
     7501 agctgccgct ccaaccagtc ttcaggttgt ctggtctaca ccagctcgca acaacgctcc
     7561 gggctctccc agataccagc tccagatgag gcctggtccc tccactcatg gccgtctaga
     7621 attattcccc attccttctg catcgttaag ctacgaagtg actggtctcc agccgttcac
     7681 agtgtatgag tttcggttgg ttgccaccaa tggctttggc actgcataca gtgcttggac
     7741 tccgctcatg actacagagg acaagcctgg acctatagat gctccaattc ttatcaatgt
     7801 gaaagctagg atgttgtcgg tcatctggag gcagcctgca aagtgcaatg gggccattac
     7861 ccattataac atctacctgc atggccgtct ctacttaaca gtctctggac gagtcactaa
     7921 ctatactgtg gtccctctgc atccttacaa ggcctatcac ttccaggtag aagcctgcac
     7981 ctcccaaggg tgctctaagt caccatcgtc tgagactgtg tggacactcc caggaaatcc
     8041 agaaggcatc ccaagcccac agttgttccc atacactcca acatcaatca tagtaacttg
     8101 gcaaccctcg gcacacctgg atctcttggt tgagaacgtt acaatcgaga gacgagtcaa
     8161 agggaaaaag gaagttagga acctggtgac cctggcaaga agtcaagcca tgaagtttat
     8221 tgataatgat cctgccctcc gcccttggac acgctatgaa taccgggttc tggggagcac
     8281 tcttgatggg ggcacaaaca gcagtgcttg ggtagaagtg accacaagac cctgtcggcc
     8341 ttccggagta cagccaccca cagtgcgtgt gctggcacca gatacagtcg aggtctcttg
     8401 gaaagcccca cttatgcaga acggagatat actgagctat gagatacgaa tgccagagcc
     8461 tctcatcaaa atgaccaata tgagctccat catgttgagt catctggtca agcatctgat
     8521 ccctttcaca aactattcag tcaccatcgt tgcttgctct ggaggtaacg ggtacctagc
     8581 agggtgcacg gagagcccac ccacccttgc tactactcac ccagccccgc ctcaggaact
     8641 ggccccgttg tctgtgattc ttctaagtga atctgatgtt gggatttctt ggcagccacc
     8701 atccaaacca aatggaccaa atttgagata cgagcttctg agatgtaaaa tccagcagcc
     8761 acttgcttca aatcccccag aagatttaaa tctgtggcac aatatttact caggaactcg
     8821 gtggttttac aaagataagg gtcttagcag gttcacaacg tacgaatata agctctttgt
     8881 acacaacagt gtgggcttta caccaagccg agaagtgaca gtcaccacct tagcaggctc
     8941 tccagagaga ggagccacgg tcaccgcaag catccttaat cacacagcca tagacgtgag
     9001 atggaagaaa ccaacatttc aagatctaca aggtgatgtg gaatattaca cactgttttg
     9061 gagttctggg acctcagagg aatctctgaa aatcttcccg gatgtagact ttcacgtcat
     9121 tggccagtta tctccaaacg tggagtacca ggttttcctc ttggttttca atggagtcca
     9181 cgcaatcaac agcacagttg tgcatgtgac catgtgggag gaggagcctc agggcatgct
     9241 tcccccagag gttgtcatca tcaacagtac agctgtacgt gtcatctgga catcgccttc
     9301 aaacccaaat gccgttgtca ccgagtcttc tgtctatgta aataataagc tctacaagac
     9361 tggaacggat gcgcccgggt cgtttgttct ggaagacctg tctcccttca ctatctatga
     9421 cattcaggtg gaagtctgta caaaagacgc ctgcgtgaaa agcaatggaa cgcaagtcag
     9481 cacagcggaa gatactccaa gtgacatttc aatacctgta atccgaggta ttacttcaag
     9541 atcccttcaa atagattgga caacaccagc aaatccaaat ggtatcattc ttgggtatga
     9601 cgttttgcgg aaaacatggc gcccatgctc tgaaacccag aagttaacag acaaaccgcg
     9661 tgatgagctt tgcaaagcag tcaagtgcca ataccctgga aaagtctgtg ggcacacgtg
     9721 ctactctcca ggaactaagg tatgttgtga cggacttctg tatgaccctc agcctggata
     9781 cagctgctgt gaggacaaat acatcgcact ctctccgaat gccactgggg tttgctgtgg
     9841 agggcgaatg tgggaggcac agccagacca ccagtgctgc tctgggcatt acgctagaat
     9901 ccttccagga gagatatgct gccccgatga gaggcacaac cgggtgtccg tgggctttgg
     9961 tgatgcctgc tgcggcacaa tgccttatgc cacctctggg agccaggtgt gctgtgccgg
    10021 gaggctccag gacggctata gacagcagtg ctgtggggga gagatggtga gccaagattt
    10081 ccagtgctgt ggtggaggag aagagggcat ggtatacagt tacctcccag gaatgctgtg
    10141 ttgtgggcag gattatgtga atatgtcaga gaccatatgc tgttcagctt ccagtggaga
    10201 gtctaaagca catgttagaa aggatgaccc cacaccagtg aaatgctgcg gcactgaact
    10261 gagtccagag agccagcgat gctgtgatgg ggttggatat aatcctttga aatatgtttg
    10321 ttctgatgag atttcagctg gaatggcgat gaaggaaacc agagtatgtg cgactatctg
    10381 cccagcaacc atgaaagcca cagcacactg tgggaggtgt gacttcaacg ccaccaccca
    10441 tatctgcacg gtgatgagag ggcctctcaa tcccacaggg aagaaagcgg tggaaggact
    10501 gtgttctgca gcagaggaaa tagttcattc tggagatgta aacacacact ctttcataga
    10561 tagagacctc aagccaagca ctgtgtatga atatagaatt tctgcatgga acagctacgg
    10621 gcgaggattc agccaatccg tgagagctag cacaagagaa gatgtgcctg aaggagtcaa
    10681 ggcccctaga tgggccagga cgggcaaaca tgaagatgtt attttcttac agtgggaaga
    10741 gcccatgcag tcaaatggtc ctatcattca ctatattctt tttcgagacg gaagggagcg
    10801 ctttcaggga acagcgctga gcttcacgga cacgcaggga attcagccac tccaggaata
    10861 ctcataccag ctgaaggctt gcacagctgc tggttgtgct gtcagttgca aggtagtcgc
    10921 tgccaccacc caaagaagcc cggagaatgt cccaccacca aacatcacag cccagagctc
    10981 agagactcta cacctcagct ggagtgtccc cgagaaaatg aaagatgcca ttaaagcata
    11041 ccagctctgg ctggatggga aagggctcat ctacaccgac acaagtgaca ggaggcagca
    11101 tacggttaca ggtctccagc catacacaaa ctacagcttc acactcgcgg tttgtacatc
    11161 tgtcggatgc acttccagtg agccctgtgt aggtcagact ctgcaggctg cccctcaagg
    11221 agtttgggtg acaccgcgac acattatcat caattctaca accgtggagc tatattggaa
    11281 tcctccagaa aggcccaacg gcctcatttc tcaatatcag ctgaggcgta atggaagctt
    11341 gcttctcgtg gggggcagag ataatcagag tttcactgat agcaacctgg agcccggcag
    11401 caggtacatt tacaagttgg aagcgagaac tggaggtggt agcagttgga gtgaggacta
    11461 ccttgtccag atgcctctgt ggaccccaga agacattcat cccccatgta atgtcactgt
    11521 gctgggctct gattccatat ttgtagcatg gccaacacca gggaacctgc ttcccaaaat
    11581 tccagtcgag tacagcatct tactcagtgg cgggagtgtg acgctcttag tcttctctgt
    11641 cagacaccgg caatctgcac acctgaaaaa cctgtctccg ttcacacagt atgaaatacg
    11701 gatccaagcc tgccaaaatg ggggctgtgg agtcagccct gggacatacg tcagaacgct
    11761 tgaagcagca cccgtgggtc tgatgccccc tcttctgaag gctctggggt catcttgcat
    11821 agaggttaag tggatgccac caacgagacc caatggaatc atcactagct atgtcgttca
    11881 caggcgtcct gctgacactg aagaagagtc tctgctcttt gtctggtcag aaggagctct
    11941 ggagtttact gatgatacag gcactctgcg gccttttaca ctgtatgagt accgggtgag
    12001 agcctggaac tcccagggtg cagtggacag cccgtggtcc acaatacaga ccctggaagc
    12061 cccacctcga ggcctcccag caccacgggt tcaagccacc agtgctcatt cagccatgct
    12121 aaactggaca gagccagagg cccccaatgg cctcatctcc cagtaccatg tgatctacca
    12181 agaaagacca gatgcggcag cacccggcag ttctaccgtg catgctttca cggtgacggg
    12241 aacgagtcgt caagcccatc tctttggctt ggaaccattc acaacatacc acattggtgt
    12301 ggtggctgta aacagtgcag gaaaggtgtc gagcccctgg accctgatta agactttaga
    12361 atctgcccca agcggactga tgaacttcac agtggagcag agagaaaagg gccgggcttt
    12421 gctgctgcag tggtcagagc cagtgaagac caatggagtg atcaaggcat acaacatctt
    12481 caatgatggg gtcctggagt actctggcct gggtcggcag tttctcttca ggcgcctggc
    12541 ccccttcact ctctatacct tgatcctgga ggcctgcacg acagcaggct gtgctcactc
    12601 ggtgcctcag cctctctgga cagaggaagc ccctccagat actcagatgg ctcctaccat
    12661 ccagtctgtg gggcccacca atgtaaggct gcactggtct cagccggcta gccccaatgg
    12721 gaagataatc cattacgaag tgatccgcag acgctcggag gaagaggact gggggaacac
    12781 aacatggcag gcagacggga acactgtttt cacagaatac aacacgcaag ggaatgcatg
    12841 ggtgtataat gacacgggtc tgcagccgtg gaggcagtat gcttatagaa tctgcgcttg
    12901 gaattctgca gggcacacct gtagctcttg gaatgtggtg agaacattgc aagcaccccc
    12961 agatggcctc tctccaccag agatatccta tgtgtctatg agtcccctcc aactgctgat
    13021 ttcctggctt ccaccccgac actctaacgg tgtcatccag ggctacagac ttcaaagaga
    13081 tggagtgctt cctgctctca atttcaatgc cagcaccttc agctacatgg acagccagct
    13141 gcttcccttc tcaacgtaca gttatgccat cctggcctgc acaggtggtg gctgctgtac
    13201 cagtgaaccc accaacatca ccactcctga ggtacctcca tcagaagtca gccctccagt
    13261 tctttgggac atcagtgccc accagatgaa tgtgtcttgg tccccgccat caatcccaaa
    13321 tggaaagatt gttaaatatt tgcttcaatg cgatggtgag gagcacctgg ctgggcaggg
    13381 tctgtccttt ctgctctcta acctgcagcc ttccactcag tataatatct cccttgtggc
    13441 ctgcacaagt ggagggtgca ctgctagtag gaccacatcc gcctggacaa aggaggctcc
    13501 accagagaac atggacccac caacactgca catcacaggc ccagaatcaa tagaaattac
    13561 atggacacct ccaagaaacc cacatggcct gatcagaagt tatgagcttc ggagagatgg
    13621 agccattgtg tatgtaggtc tggaaactcg ctaccatgat tttacccttg ctcctggtgt
    13681 tgaatacagc tactcggtga ctgccactaa cagccggggc agtgtcttga gcccacttgt
    13741 caagggtcaa actagcccct cagccccctc aggtttacag cccccaaagc tgcattcggg
    13801 ggatgctctt gagctcttag ctgattggga ccctccggtg aggacaaacg gcaagatcat
    13861 caactacact ctcttcgtcc gtgagatgtt tgaaggaaaa accagagcca tgtccattaa
    13921 cacaacacac agttcttttg gcacacggtc actcacggta aagcacctga agccgtttca
    13981 taggtatgaa gtgcgtgtcc aagcctgcac tgccctcggg tgtacctcca gtgagtggac
    14041 atctacccaa acctcagagg tcccaccact gaggcagcca gccccacatc tggaggtgca
    14101 gacagctaca gggggattcc agcccatagt agccgtgtgg tgggcaggac cacttcagcc
    14161 aaatggaaaa atcatatgct ttgaattgta cagaagacaa gtagcagcct ggcctggcac
    14221 atccagttca ctgctaatct acaacggcag cttccgctcc tttatggact cagagctact
    14281 accattcacg gaatacgaat accaggtatg ggcggtgaat tctgcaggca aagctgcaag
    14341 taactggaca cggtgcagaa ctggacctgc cccaccggaa ggtctccaag cgcccacatt
    14401 ccacaccgtc tcctccaccc gagcggtggt caacatcagt gtgccttcga gacccaatgg
    14461 gaacatcagc ctcttcaggg tcttctccaa ctccagcggg acgcacgtca cgctgtctga
    14521 aggcaccgcc acccagcaga cccttcatga cctgagtccc ttcaccacat acaccattgg
    14581 ggttgaggcc tgcacctgct tcaactgctg cagccgaggc ccgacagccg agctgaggac
    14641 ccaccctgcc ccgccctcag ggctgtctcc tccccaggtc cagacactgg gctccaggat
    14701 ggcctccgtc cactggactc cccccctgct ccccaatggt gtcattcaca gctatgagct
    14761 gcagctgcag cgggcttgcc ctcctgattc agccccacgc tgccctccaa gccacacaga
    14821 aaggaagtac tggggccctg ggcacagagc cagcctggcg gggcttcagc ctaatactgc
    14881 ctacggggtg caagtggtgg catacaatga agcaggcagc acggcttccg ggtggaccaa
    14941 cttcagcacc aagaaggaga tgcctcagta ccaagccctg ttctcagtgg acagcaacgc
    15001 atccatggtg tgggtggact ggagtggcac ttttctcctg aacggccatc taaaggagta
    15061 cgtggtcacc gacggaggac ggagggtgta cagtggccta gacaccacac tctacatacc
    15121 aaggatggtg gacaaaattt tcttcttcca ggtcacctgc acgaccgaca ttggaagtgt
    15181 taagactcca ctggtccaat atgatgctgc tactggatct ggcctggtgc tgacaactcc
    15241 tggagaaaag aagggagcag ggaccaaaag cacagagttc tacagtgagc tgtggtttat
    15301 tatggtaatg gctgtggtgg gcctgatctt gttggccatt tttctgtcct tgattctaca
    15361 aagaaaaatc cacaaggaac catgtatcag agagcgacct cccttggtac ctcttcagaa
    15421 acgaatgacc ccactgagcg tctacccacc aggggaaacc catgtgggat tagccgacac
    15481 cagactccct aggtctggga cacctatgag tattcggagc agccaaagtg tgtctgtact
    15541 gcggatccca agtcaaagcc aactgagcca cgcctactcc cagagctctc tccaccgcag
    15601 tgtcagccag ctcatggaca tggcagacaa gaaggttgtt acggaagact cactgtggga
    15661 aactattatg ggccacagca gtggactgta tgtggacgaa gaagagctca tgaacgccat
    15721 caagggtttc agctccgtga ccaaggagca caccgccttt accgacaccc acctctgaat
    15781 aaacaatcaa gttagagcgt ggaaccctgg gatgcatgct ctgcacactg tttttttttt
    15841 ttttccagtt gccaccacat gtgataaaag ctgaaaaaag ctgaaacaaa a
//
