LOCUS       NM_144940               3365 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus urocanase domain containing 1 (Uroc1), transcript
            variant 2, mRNA.
ACCESSION   NM_144940 XM_983419
VERSION     NM_144940.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3365)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK149464.1 and AC163346.3.
            
            On Apr 4, 2008 this sequence version replaced NM_144940.1.
            
            Transcript Variant: This variant (2) lacks an alternate in-frame
            exon in the coding region, compared to variant 1. It encodes a
            shorter isoform (2), compared to isoform 1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            transcript and genomic sequence to make the sequence consistent
            with the reference genome assembly. The genomic coordinates used
            for the transcript record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC022133.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849385, SAMN00849386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-932               AK149464.1         2-933
            933-1920            AK149464.1         1036-2023
            1921-3365           AC163346.3         136894-138338       c
FEATURES             Location/Qualifiers
     source          1..3365
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 40.15 cM"
     gene            1..3365
                     /gene="Uroc1"
                     /note="urocanase domain containing 1"
                     /db_xref="GeneID:243537"
                     /db_xref="MGI:MGI:2385332"
     exon            1..156
                     /gene="Uroc1"
                     /inference="alignment:Splign:2.1.0"
     exon            157..287
                     /gene="Uroc1"
                     /inference="alignment:Splign:2.1.0"
     exon            288..381
                     /gene="Uroc1"
                     /inference="alignment:Splign:2.1.0"
     exon            382..441
                     /gene="Uroc1"
                     /inference="alignment:Splign:2.1.0"
     exon            442..570
                     /gene="Uroc1"
                     /inference="alignment:Splign:2.1.0"
     exon            571..632
                     /gene="Uroc1"
                     /inference="alignment:Splign:2.1.0"
     exon            633..699
                     /gene="Uroc1"
                     /inference="alignment:Splign:2.1.0"
     exon            700..843
                     /gene="Uroc1"
                     /inference="alignment:Splign:2.1.0"
     exon            844..932
                     /gene="Uroc1"
                     /inference="alignment:Splign:2.1.0"
     exon            933..995
                     /gene="Uroc1"
                     /inference="alignment:Splign:2.1.0"
     exon            996..1175
                     /gene="Uroc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1176..1273
                     /gene="Uroc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1274..1346
                     /gene="Uroc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1347..1468
                     /gene="Uroc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1469..1539
                     /gene="Uroc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1540..1638
                     /gene="Uroc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1639..1738
                     /gene="Uroc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1739..1820
                     /gene="Uroc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1821..1920
                     /gene="Uroc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1921..3365
                     /gene="Uroc1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3341..3346
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Uroc1"
                     /note="hexamer: AATAAA"
     polyA_site      3365
                     /gene="Uroc1"
                     /note="major polyA site"
ORIGIN      
        1 atacttgcct ccacctcagc ttctgcagac atgtccagcc tccaggaact gtgctctggt
       61 ctgcccctac gaccccttcc tgagaaccgg ggtcgctggg ctggggtgcc acatgctccg
      121 gttagaactc cgaacctcag ccctgaagaa gagcagctgg ccctgaggaa tgccttgcgc
      181 tatttcccac ctgatgtcca gaaactgttg gccctggagt ttgcccagga gctaagacag
      241 tttggacaca tctacatgta ccggttctgc cccagcattg agatgagagc ctacccaatt
      301 gatcagtacc catgccggac acgggcagct gcagccatca tgcacatgat catgaacaac
      361 ttggaccctg ctgtggccca gtttccacag gagctggtga cctacggagg caacgggcaa
      421 gtgttcagca actgggccca gttccggctg accatgtcct acctgtcgaa gatgactgag
      481 gaacagactc tggtcatgta cagtggacac cctctgggcc tcttccccag cagcccccgt
      541 gccccacggc tggtcatcac taacgggatg gtcattccca actactcctc caggacagag
      601 tatgagaagc tgtttgcctt gggggtgacc atgtatggcc agatgacagc gggcagctac
      661 tgctacattg gtccccaggg aatcgtccat ggcacagtgc tcactgtgct gaatgctggt
      721 cgtcggtacc tgggcatcga gaacttggca gggaaggtct ttgtcacctc tgggcttggc
      781 gggatgagtg gggctcaagc caaggcagca gccatcgttg gatgcattgg ggtgattgcg
      841 gaggtggata aagctgcact tgtaaaacgc caccggcaag gctggctgat ggaggtgaca
      901 gacagcttgg accgctgcat tgcaagactc agggaagcaa ggaaaaagaa ggaggttctc
      961 agcctcggct accatggcaa cgtggtggat ctttgggagc gccttgtcca tgaactggac
     1021 acaacggggg aactcttggt ggacctcggg tcagaccaga catcctgtca caacccgttc
     1081 aatggcggct actaccctgt gcagctcagc ttctcagagg cccagagcct catgtcctcc
     1141 aaccctgctg ccttcaagca cctggtgcag gaaagcctga ggaggcatgt cgcagccatc
     1201 aacaggttgg cccaagagaa gttcttcttc tgggactatg gtaatgcctt cctcttggag
     1261 gctcagagag caggagcaga tgtagagaag aaaggagcca acaagatgga gttccgctac
     1321 ccctcctatg tccagcacat tatgggggat atattctccc agggctttgg gcccttccgc
     1381 tgggtatgca catcagggga cccccaggac ctggctgtca ctgatcatct ggccacatct
     1441 gtactggaga aagccattgc tgatggagtg aaggcatctg tgaagctaca gtatatggat
     1501 aatatacgct ggatccgaga ggctgccaag catcagctgg tggtgggctc ccaggcaagg
     1561 atcctgtact cagaccagaa aggccgtgtg gccattgctg tggccattaa ccaggccatc
     1621 gccagtggga agatcaaggc accagtggtc ctgagccgtg accaccatga tgtgagtggc
     1681 actgacagcc ccttcaggga gacttcgaat atttatgacg gttctgcctt ctgcgcagac
     1741 atggccgtgc agaacttcgt gggagatgcc tgtcgtggtg ccacctgggt tgcacttcac
     1801 aatggagggg gtgtaggctg gggtgaagtc atcaatgggg gatttggcct tgttctagat
     1861 ggaactgcag aggctgagca gaaagccagg atgatgctca gctgggatgt ctccaatggt
     1921 gtggcacgac gctgctggtc tggaaacccc aaggcctatg agatcatctg ccagacaatg
     1981 caggagaaca gtggcctggt ggtgacgctt ccccatgagg tggcagatga acaagtgcta
     2041 cagcaggccc tgcggccctg agaagagcaa gggtcctctt gatcccctcc ttcccactgc
     2101 cctcccctcg cagctcatga ccctccccca ccccactgca tccctacatg gcactcttcg
     2161 tgtcccacat actaaccaca gaggcctatc aaggtgaagg cgctagtctt tgaccactgg
     2221 tttgagggca gggtacatct tgttcatgaa caggcctgta agagtagact ccagcttgga
     2281 taggaaggaa ccttgaatgc tggccaagct ggcacccgcc tcacaagatt ctctgtgacc
     2341 ttctaaatgt gctgttcagt ctcctatcta ctactgtcca cgcagttacc cagccatccc
     2401 ttgtctatgt catccatcac ttccggttcc tcagagaacc tggcattctc tcatgggttc
     2461 acaaagtgct cacaccaagt ccttggtgct gaggagtatg ggggaagata gacaggaaat
     2521 aaagactaga gtagagccaa acacatggca cagactgggc tagcaagagt ggataacaga
     2581 gtctctgagg caaagtggcc aggtgctgct gcaacatgtg gagaaaaggc aattgtgtga
     2641 ccatgaaaaa cagaaccaac cacttccaga ggtccctggg tggatctgga atcctgcagg
     2701 agttgcatta gccataagct gggttcttat atctttccca tggcctgcaa tccaacctct
     2761 gaagcaggag acctagcaag aaagttgggt agctgtgctt cctccccctc cccctggaag
     2821 ttgccactac tttataatgc ctcctaaccc ccaataccca tcttttaggc cccttcccac
     2881 taccatgtcc tgtgccctct tttcaatctt caccaggcca gatctcctgc tgtgtgatcc
     2941 cctaaactga ggcaggccta caaggcagtt aacttacaaa gagaaaaagg attttttttt
     3001 tttttttttt ttttttggct gaccattctg gatgttccca cgcaagataa ggaagtcgtg
     3061 ttgctttggg cctctggcaa caatgccaag tggcaatggc agggagcaca tggcagagca
     3121 aaattacact atgagccagg aagaaagaag agacgcttgg acccaagtcc tccaatcctt
     3181 caagggtgtg ttccagtagc ctaaagccct ttccctagct ccacttctaa aggtcccctc
     3241 acctccctgc acagctttgg aataagcctt tagcccatct gcagccatag cagaggtcaa
     3301 aatcggcttt ctggcatttt ggtctatgtt tcttgcatta aataaagatt ttcctaaatc
     3361 aaaaa
//
