LOCUS       NM_178623               5115 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus upregulator of cell proliferation (Urgcp), transcript
            variant 1, mRNA.
ACCESSION   NM_178623
VERSION     NM_178623.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5115)
  AUTHORS   Diez-Roux,G., Banfi,S., Sultan,M., Geffers,L., Anand,S., Rozado,D.,
            Magen,A., Canidio,E., Pagani,M., Peluso,I., Lin-Marq,N., Koch,M.,
            Bilio,M., Cantiello,I., Verde,R., De Masi,C., Bianchi,S.A.,
            Cicchini,J., Perroud,E., Mehmeti,S., Dagand,E., Schrinner,S.,
            Nurnberger,A., Schmidt,K., Metz,K., Zwingmann,C., Brieske,N.,
            Springer,C., Hernandez,A.M., Herzog,S., Grabbe,F., Sieverding,C.,
            Fischer,B., Schrader,K., Brockmeyer,M., Dettmer,S., Helbig,C.,
            Alunni,V., Battaini,M.A., Mura,C., Henrichsen,C.N.,
            Garcia-Lopez,R., Echevarria,D., Puelles,E., Garcia-Calero,E.,
            Kruse,S., Uhr,M., Kauck,C., Feng,G., Milyaev,N., Ong,C.K.,
            Kumar,L., Lam,M., Semple,C.A., Gyenesei,A., Mundlos,S., Radelof,U.,
            Lehrach,H., Sarmientos,P., Reymond,A., Davidson,D.R., Dolle,P.,
            Antonarakis,S.E., Yaspo,M.L., Martinez,S., Baldock,R.A., Eichele,G.
            and Ballabio,A.
  TITLE     A high-resolution anatomical atlas of the transcriptome in the
            mouse embryo
  JOURNAL   PLoS Biol 9 (1), e1000582 (2011)
   PUBMED   21267068
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY058620.1 and AL627069.10.
            
            On Nov 13, 2006 this sequence version replaced NM_178623.2.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BY059282.1, AK033577.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849385
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-268               BY058620.1         1-268
            269-5115            AL627069.10        18509-23355         c
FEATURES             Location/Qualifiers
     source          1..5115
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 3.87 cM"
     gene            1..5115
                     /gene="Urgcp"
                     /gene_synonym="2010005J08Rik; 9130001I21Rik; mKIAA1507;
                     Urg4"
                     /note="upregulator of cell proliferation"
                     /db_xref="GeneID:72046"
                     /db_xref="MGI:MGI:1919296"
     exon            1..80
                     /gene="Urgcp"
                     /gene_synonym="2010005J08Rik; 9130001I21Rik; mKIAA1507;
                     Urg4"
                     /inference="alignment:Splign:2.1.0"
     CDS             67..2847
                     /gene="Urgcp"
                     /gene_synonym="2010005J08Rik; 9130001I21Rik; mKIAA1507;
                     Urg4"
                     /note="isoform 1 is encoded by transcript variant 1;
                     protein URG4; up-regulator of cell proliferation; HBxAg
                     up-regulated gene 4 protein homolog; HBV X protein
                     up-regulated gene 4 protein homolog"
                     /codon_start=1
                     /product="up-regulator of cell proliferation isoform 1"
                     /protein_id="NP_848738.2"
                     /db_xref="CCDS:CCDS36104.1"
                     /db_xref="GeneID:72046"
                     /db_xref="MGI:MGI:1919296"
                     /translation="MASPGIEVELLVKGHSDLGEVAPEVKPSDSQTSVAIADLEWREM
                     EGDDCGFHYGDGTNEAQDNDFPTVERSRLQEMLSLLGLETYQAQKLTLQDSLQISFDS
                     MKNWAPQVPKDLPWHFLRKLQALNAEARNTTMVLDVPPEAWPAEKESQAEEEMMYWDP
                     AEDVAADIYSFSELPMPDTPVNPLDLLCALLLSSDTFLQQEVLLKMSLCQFALPLVLP
                     DSENHYHTFLLWALRGVVRTWWFQPLRSLGSFREDSVVLSRVPTFAFVRMDVSSNSKS
                     QLLNAVLSPARRQWDCFWHRDLNLGTNPREISDGLVEISWFFPSGKEDLDVFPEPMAF
                     LNLRGDIGSHWLQFKLLTEVSSAVFILTDNISKKEYKLLYSMKESTTKYYFILSPYRG
                     KRNTNLRFLNRLIPVLKIDHSHVLVKVSSTDSEGFVRRIRAIMCSVARSPCRRVSVED
                     MAHAARKLGLRVDEDFEECQKAKDRMEKILRKIKDVDAYKRDELRLQGEPARRAAQAE
                     REFCQLQWVPEPPEKHRAELRRRVLELRVQQNGQEPTSGVQEFILGISSPSPSERQYF
                     LRWMEWGLARLGQPRPRQPPETLLTLRPKLGGPSDLTEPLWPEPLGVEHFLREMGQFY
                     EAESCLIEAGRLPAGQRRFAHFPGVAVELLLGGLPLELVDGATLSIPVRWVTGLLKEL
                     HTRLDRRSRLVVLSALGVPGTGKSTLLNTMFGLKFATGRSCSPRGAFMQLLPVAEGFS
                     QDLGCDQILVIDSGGLISGALASAGDRFELEASLATLLMGLSNVTVVSLAETKDIPPA
                     VLHAFLRLEKMGHMPNYQFVYQNLHDLPVPSPKPRDRRQLLDPPSDLSRATHLEKQGG
                     GFRTLAGLAERQHVWHIPALWHGAPPMAAVSLGYSEAIFELKRCLLENIRNGLSNQNQ
                     NIQQLIELLRRL"
     misc_feature    73..75
                     /gene="Urgcp"
                     /gene_synonym="2010005J08Rik; 9130001I21Rik; mKIAA1507;
                     Urg4"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q8TCY9; propagated from
                     UniProtKB/Swiss-Prot (Q5NCI0.1); phosphorylation site"
     exon            81..107
                     /gene="Urgcp"
                     /gene_synonym="2010005J08Rik; 9130001I21Rik; mKIAA1507;
                     Urg4"
                     /inference="alignment:Splign:2.1.0"
     exon            108..178
                     /gene="Urgcp"
                     /gene_synonym="2010005J08Rik; 9130001I21Rik; mKIAA1507;
                     Urg4"
                     /inference="alignment:Splign:2.1.0"
     exon            179..229
                     /gene="Urgcp"
                     /gene_synonym="2010005J08Rik; 9130001I21Rik; mKIAA1507;
                     Urg4"
                     /inference="alignment:Splign:2.1.0"
     exon            230..268
                     /gene="Urgcp"
                     /gene_synonym="2010005J08Rik; 9130001I21Rik; mKIAA1507;
                     Urg4"
                     /inference="alignment:Splign:2.1.0"
     exon            269..5115
                     /gene="Urgcp"
                     /gene_synonym="2010005J08Rik; 9130001I21Rik; mKIAA1507;
                     Urg4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3529..3534
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Urgcp"
                     /gene_synonym="2010005J08Rik; 9130001I21Rik; mKIAA1507;
                     Urg4"
                     /note="hexamer: AATAAA"
     polyA_site      3549
                     /gene="Urgcp"
                     /gene_synonym="2010005J08Rik; 9130001I21Rik; mKIAA1507;
                     Urg4"
                     /note="major polyA site"
     regulatory      4787..4792
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Urgcp"
                     /gene_synonym="2010005J08Rik; 9130001I21Rik; mKIAA1507;
