LOCUS       NM_001368414            5817 bp    mRNA    linear   ROD 06-AUG-2023
DEFINITION  Mus musculus URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
            (Urb2), transcript variant 2, mRNA.
ACCESSION   NM_001368414 XM_006531151
VERSION     NM_001368414.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5817)
  AUTHORS   Okazaki N, Kikuno R, Ohara R, Inamoto S, Aizawa H, Yuasa S,
            Nakajima D, Nagase T, Ohara O and Koga H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC139575.3.
            
            On Feb 12, 2019 this sequence version replaced XM_006531151.3.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Variants 1 and 2 both encode the same protein.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR10223970.10879.1,
                                           SRR10223971.8844.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-30                AC139575.3         99424-99453         c
            31-169              AC139575.3         97352-97490         c
            170-346             AC139575.3         95718-95894         c
            347-3677            AC139575.3         89761-93091         c
            3678-3838           AC139575.3         85762-85922         c
            3839-3949           AC139575.3         84204-84314         c
            3950-4192           AC139575.3         82547-82789         c
            4193-4280           AC139575.3         79697-79784         c
            4281-4420           AC139575.3         75732-75871         c
            4421-5817           AC139575.3         72445-73841         c
FEATURES             Location/Qualifiers
     source          1..5817
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 72.33 cM"
     gene            1..5817
                     /gene="Urb2"
                     /gene_synonym="mKIAA0133"
                     /note="URB2 ribosome biogenesis 2 homolog (S. cerevisiae)"
                     /db_xref="GeneID:382038"
                     /db_xref="MGI:MGI:2681124"
     exon            1..30
                     /gene="Urb2"
                     /gene_synonym="mKIAA0133"
                     /inference="alignment:Splign:2.1.0"
     exon            31..169
                     /gene="Urb2"
                     /gene_synonym="mKIAA0133"
                     /inference="alignment:Splign:2.1.0"
     CDS             44..4618
                     /gene="Urb2"
                     /gene_synonym="mKIAA0133"
                     /codon_start=1
                     /product="unhealthy ribosome biogenesis protein 2 homolog"
                     /protein_id="NP_001355343.1"
                     /db_xref="CCDS:CCDS22768.1"
                     /db_xref="GeneID:382038"
                     /db_xref="MGI:MGI:2681124"
                     /translation="MAAVYSGISFKLKSKTTSWEDKLKLAHFAWISHQCFLPNKEQVL
                     LDWARQSLVAFYKKKLELQEDIVERLWIYVDNILHSKKLQNLLKDGKTVNLQLSLVKI
                     INERIEEFSRSGCQRNICAVLSCCQGILSAPALAVIYTAKPELIVALLSQLCWSACRQ
                     PEGATTAKLFEVIHLALDHYLRLQQQQANPKRVFGDMTGHLFQPCLVLRHLLLGGTWT
                     QASQGQLWQVLSRDIRSKIDAVLRAGVFRHDLLSSYKEELLEQHQESVRMGVLKGLLT
                     PMEAVIARLVEPGYVRSDLHALVVASSVPLLFRLFLEAYLQEESQFLCFQVLPRLFGC
                     LQISHLQEGQIEALSLSDWTTELLAIEQLLNSVATSNIYNVATDRIRHAETQFHFYRR
                     VAEVLINHSQASVPAWFRCLKILISLNHLILEPDLDDLLSSAWIDAEVTEFRAKKAQE
                     VLINTVFQTYAKLRQVPRLFEEVLGVICRPAAEALRQPLLASGLSVALSACLLELPLS
                     QILDSWSLVLDKFQSLVMPCLQSDTDMALKAMSLSSLLHCIMFNMQSLDNNMPLPIIR
                     RTQCIMERMLRELVGPLLGLLLDLWSPEPELWQQKVCDSALLLSYTWAQVDATISLHC
                     SQYYSLGISLARAALDSSNLPLLLPGVEMEFWKKVEECVGQSRSLSRYCLEQLYLQKV
                     KRTLMRSNSQSKEALQTLRFDTAHILDSSRDCLSQKTAAAWDRQVSTMNESIYPVAHW
                     HLIVSNLTVLIPYLCLNDVRYVATVLLRTLPASKAQGSLAHGEPHVTLEKISTALLHS
                     PLFPEMQSLYSAFLTCIIAECSSTLCSGAHSDLSLVSQQLPWLSGKDDHTIVAHWETR
                     LAKVGPEGVEPRGEIAQNFLSMVKSGFPIKLDEEQLKGLLELLEVISALRLDSLSPSY
                     HVHMFFLLFSMAVSTLGHCSCPLALQFLVKCYRLLSSLQRGKNGRTVFRVMYVSDIFE
                     VVLTSLLQASAEFQVREDDPAWLQLLQVSGVFLEQLMQMLTQVKLSLVLNFGKITAFL
                     SRYRKEASCKEGKIPNLRSRQLLLVALTKLCQSLGPCVKERRQLLEAPAELAELLQQA
                     MMQMGTMLKLCLVSGTTGRRRLPSVLLAAVPTLLEVDMSQHLRDGQPKIAQVVDTDKT
                     LLSHGTLYQDVYTQLLEELPALSGNAQSFQAALQFLTLFLLAPELHSKETSVFASVFY
                     SVQKVLTGPCIPAPVTQDTELHLGALLTQMFEAGTTEHFGMVLQSILQGLDVTQAWRS
                     DLQVVLCAIRLLKLLLKCPLNGEKASLLWRSCPQIITALMLQHREACREQPVALAVIE
                     PVLEVLAVLLRKGEESISNPHHVSLAFNILLTVPLEHLQPREFGSVFLKMHSVLFSIL
                     QCHSKVMLKAVPSFLNSFNRLLVSVMHEGRQKDKGSVDDLTVVLESARLVERMYSHLA
                     TRAEEFTAFSPFLVAQYVTEVQKVTLYPPVKNLLQEGIYLILDLCMERDIQFLRASLQ
                     AGARDVFKDLHSDYLKYHKAKHEGEKRYTA"
     exon            170..346
                     /gene="Urb2"
                     /gene_synonym="mKIAA0133"
                     /inference="alignment:Splign:2.1.0"
     exon            347..3677
                     /gene="Urb2"
                     /gene_synonym="mKIAA0133"
                     /inference="alignment:Splign:2.1.0"
     exon            3678..3838
                     /gene="Urb2"
                     /gene_synonym="mKIAA0133"
                     /inference="alignment:Splign:2.1.0"
     exon            3839..3949
                     /gene="Urb2"
                     /gene_synonym="mKIAA0133"
                     /inference="alignment:Splign:2.1.0"
     exon            3950..4192
                     /gene="Urb2"
                     /gene_synonym="mKIAA0133"
                     /inference="alignment:Splign:2.1.0"
     exon            4193..4280
                     /gene="Urb2"
                     /gene_synonym="mKIAA0133"
                     /inference="alignment:Splign:2.1.0"
     exon            4281..4420
                     /gene="Urb2"
                     /gene_synonym="mKIAA0133"
                     /inference="alignment:Splign:2.1.0"
     exon            4421..5817
                     /gene="Urb2"
                     /gene_synonym="mKIAA0133"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acatgtggct cgccgccgtg gaggtcccag aagacgtgta gcaatggctg ctgtttattc
       61 tggtatttcc tttaaactta aaagcaagac aacttcctgg gaagataaac taaaattagc
      121 tcactttgct tggatttccc atcagtgctt tctaccaaat aaagaacaag ttttacttga
      181 ttgggcaagg cagtcattgg ttgcatttta taagaaaaag cttgaactgc aggaagatat
      241 tgttgaaagg ctctggatct atgtagataa cattctacat agtaagaaat tgcagaacct
      301 ccttaaggat gggaagactg taaatctcca gctctccctt gtcaagatca taaatgagag
      361 aatagaagag ttctcacgtt caggatgcca gaggaatatc tgtgccgtcc tgagttgctg
      421 ccagggcatc ctctcagcac ctgcccttgc tgtcatctat acagccaaac cagagctcat
      481 tgtggctttg ctgagccagc tctgctggtc ggcctgcaga cagccagaag gagccacgac
      541 agccaagctg tttgaggtca ttcatctggc tcttgaccat tacctcagac ttcagcaaca
      601 acaagccaac cctaagcgtg tctttggaga tatgactgga cacctctttc agccctgcct
      661 agtcctgaga cacttgcttt tggggggcac gtggacccaa gctagtcagg gtcagctatg
      721 gcaggtactg agcagagata tcaggagcaa gattgacgct gttcttcgag ctggtgtttt
      781 tcgacacgat ttactttcat cctacaaaga ggagctcttg gagcagcacc aagagagtgt
      841 gaggatgggg gtcctgaagg gtcttctcac tccaatggaa gctgtgattg caagactggt
      901 agagcctggc tatgtcagat cagacctcca tgctttggtt gtggccagct cagtgccctt
      961 gttgtttaga ctctttctgg aagcatacct tcaggaagaa agccagtttc tctgttttca
     1021 ggttctcccc aggttgtttg gctgcttgca gatttcacac ctgcaggagg ggcagataga
     1081 agccctgtcc ctatcagatt ggactacaga gcttctggct atagagcaac tgttaaactc
     1141 agtggccacc agtaacatct acaatgtggc tactgacagg attcggcatg cagagacaca
     1201 gtttcacttc taccgccgtg tggctgaggt gctgatcaac cattcacaag catctgtgcc
     1261 agcttggttt cgctgcctca agattttgat ctctctgaat catttgattt tagagccaga
     1321 cctggatgac ctgttgtctt cggcttggat tgatgcggaa gtaacagaat ttcgagccaa
     1381 aaaggcccag gaggtactta tcaacactgt cttccagacg tacgccaaac tccgacaggt
     1441 gccacggttg tttgaggagg ttttgggggt gatctgccgc ccagctgctg aggcactgcg
     1501 gcagcctttg cttgcctcag gcctctctgt ggctctcagt gcatgtcttt tggagctgcc
     1561 actgagtcag atcctggatt catggtccct tgtgctagat aagttccagt ctttagttat
     1621 gccctgtttg cagagtgata ctgacatggc tttaaaggca atgtcactga gctctctgct
     1681 gcactgcatc atgttcaaca tgcagagtct ggacaataac atgcctctgc ccatcataag
     1741 acggacacag tgcataatgg agaggatgct gagagagctt gtggggcccc ttttgggcct
     1801 tctcctggac ctctggagtc cagagcctga gctgtggcag cagaaggtgt gtgactctgc
     1861 actcttactc tcttacacct gggctcaggt ggacgctacc atcagtttgc actgcagcca
     1921 gtattattct ctggggatct ccctagccag agctgctctg gatagttcaa acctcccttt
     1981 gttgctacca ggtgtagaaa tggagttttg gaagaaggtg gaagagtgtg taggccagtc
     2041 caggtctctc agtaggtact gcttagaaca gctgtatctt cagaaggtga aaaggacttt
     2101 aatgcggagt aattcacaat ccaaagaagc ccttcaaacc ttgaggtttg acactgctca
     2161 cattcttgat tctagcagag actgtttaag tcagaagaca gcagctgcct gggataggca
     2221 ggtgtcgaca atgaatgagt ccatatatcc tgtagcacac tggcacttga ttgtatcaaa
     2281 cctcacagtt ttaataccct acctttgttt gaatgatgtg agatatgtgg ccactgtctt
     2341 gttaagaact ttaccagcaa gtaaagccca gggaagcttg gcacatggtg agccacatgt
     2401 cacacttgag aaaatatcca cagccctcct tcacagccct ctctttccag agatgcagtc
     2461 cctctactct gccttcctga cgtgtatcat tgcagaatgt tccagcactc tgtgctctgg
     2521 agctcatagt gacctgagtc ttgttagtca gcagctcccc tggctttctg gaaaggacga
     2581 ccacacaatc gtggctcact gggaaaccag attggcaaaa gttggacctg aaggtgtaga
     2641 accaagagga gaaattgccc agaattttct atccatggtc aagagtggtt ttccaatcaa
     2701 gctggatgaa gaacagctaa aaggcctcct ggagctctta gaagtcatct ctgcccttcg
     2761 cctggacagc ctctcgccat cttaccacgt gcatatgttt ttcctgctat tctccatggc
     2821 tgtctccaca ttagggcatt gctcttgccc actagccctc cagttcttgg tgaagtgcta
     2881 ccggctcctc agtagtctgc agagaggaaa gaatggccgc actgtattca gggttatgta
     2941 cgttagtgac atctttgagg ttgtgctgac ctcactgttg caagccagtg ccgagtttca
     3001 ggttagggag gatgaccctg cttggctgca gcttcttcag gtgtcagggg tgttcttaga
     3061 gcagctgatg cagatgctta cccaagtcaa gctgagcttg gtgctcaact tcgggaaaat
     3121 cactgccttt ctctcaaggt acaggaagga agcttcctgc aaagagggga aaatcccgaa
     3181 ccttcggagc aggcaactgc ttctggtggc tctaaccaag ttgtgtcaga gtttggggcc
     3241 ttgtgttaag gagcggaggc agctactgga ggccccagca gagctagctg aattgctaca
     3301 gcaggccatg atgcagatgg gcaccatgct gaagctttgc ctagtgtccg ggactacagg
     3361 ccgccgccgc ctgccttcag tactcctcgc tgctgtcccc acacttttag aagtagacat
     3421 gagccagcac ctcagggacg gacagcccaa aattgctcaa gtggtggata cagacaaaac
     3481 actgctttct catgggacac tttaccagga tgtctacacg cagttgctgg aggagttgcc
     3541 agccctgtcg gggaatgctc agtctttcca ggcagcattg caatttctaa ccttgttcct
     3601 tttggcccca gagctccatt ccaaggagac ctctgttttt gcttccgtct tttattctgt
     3661 gcagaaagtt cttacaggtc catgcatacc tgctccagtc actcaggata ctgaacttca
     3721 cttgggagcc ctgctcaccc agatgtttga ggctgggaca acagagcact ttgggatggt
     3781 actgcagtct attcttcagg ggctggacgt cactcaggca tggaggtcag atctacaggt
     3841 tgttttgtgt gccattagac tactcaaact gctactcaaa tgtccactca acggagaaaa
     3901 ggcaagtttg ctgtggcgtt cgtgtcccca gatcatcacg gctctaatgc tgcaacaccg
     3961 agaggcctgc cgggagcagc ctgtggccct agcagtgatt gagcctgttc ttgaagttct
     4021 ggccgttctg ctccggaaag gggaggagag cattagcaac cctcaccatg tcagcctggc
     4081 cttcaacatc ctgctcacag tccctctgga gcacctgcag cctcgggagt ttggcagcgt
     4141 cttcctgaag atgcacagtg tgctcttctc catcttgcag tgccactcca aggtgatgct
     4201 gaaggccgtt ccatctttct tgaactcctt caatagactg ttggtttcag ttatgcatga
     4261 aggacggcag aaagacaaag ggagtgtgga tgacctgaca gtggtccttg agtctgcacg
     4321 cctggtggag aggatgtata gccaccttgc tactcgagct gaggagttca ccgcgttctc
     4381 cccgttcctg gtggcccagt atgtgacaga ggtccagaag gtaaccttgt acccacctgt
     4441 gaagaacctg cttcaggagg ggatttatct catcttggat ctttgcatgg agcgggatat
     4501 ccagtttctt cgggcctcac tacaggctgg agcgcgagat gtctttaagg atctgcacag
     4561 cgactacctc aagtaccaca aggccaagca tgaaggagag aaaagatata cggcctaggt
     4621 cacaccacag aatcacctgg gacaccttgc agaacattca tagttcagag tcctggagga
     4681 tgtaaggctt ctgacgttct catacacgtt gtcaacaacc atggaaaaca cacacacaca
     4741 cacacacaca cacacacaca cacacagtct cactgtatat ccttgaatgg cctagaactc
     4801 actatgtaga acaccaggct ggctttgaac tcacagagat ccctctgctt tctgtatgcc
     4861 gagtctaaat gtatcacctt gcccaccttg gggattatat atttttatag cttttttttt
     4921 taaatgctaa atgttctttg atatcccacc cctccagcag gataaagatt gaaccaggcc
     4981 ctcacacaca ctaattgcac acttctgcgg ctcagccaca cctgcatgcc tcagtgcacc
     5041 tttgaaaact aagtgtggta taagagacct ggaaatcggg actgggcttg gtggtgcaca
     5101 tctttaatcc cagcattcag gaggcagagg gaggtggatc tctgtgagtt tgaggccagc
     5161 aaagccacac acagaaacct tgtatcgaaa acaaacaaac aaataaactt ggaaatgggt
     5221 tctgagatga atttaatgga aaattcctga ccattatgac tgtacctaat gtggtccttt
     5281 ctttcctctc ttctggctgt gaactgcgta gaattgggtc tataattgaa tcctgtgtga
     5341 gtaattctgc tctttaagtt aaatcaagtt gcacagagac actttccagc tgctacactg
     5401 tgccgtcctg ttgggaattc tagtggtgct ggggaacagc cagggcccag cagggtggtg
     5461 tgcacttgtc tggtagggaa gtcctctagc acaggagaca ggactcctgc ttgttcccac
     5521 ttcagtttga gaagctgatt acaaatcttt tcctactcag ttcaaaaata acgttaacag
     5581 ttcttacgac ctaagcaata tatcatagtg gtcttgatta ttaagccttt attatcgctt
     5641 ggaaatgtct tgttttagag tctttgctgt atatatatag atacatatgt gcatatatat
     5701 atatatatat atagtaaatt gatcaaaaat gtgttttaag gtttcttaat gttttctttt
     5761 gtaatggctg tcattatctt aagagttaat aaaaaaattt ggtatttttt aatgtca
//
