LOCUS       NM_001039678             786 bp    mRNA    linear   ROD 05-FEB-2024
DEFINITION  Mus musculus ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5)
            decarboxylase (Urad), mRNA.
ACCESSION   NM_001039678 XM_149717 XM_905261
VERSION     NM_001039678.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 786)
  AUTHORS   Ramazzina,I., Folli,C., Secchi,A., Berni,R. and Percudani,R.
  TITLE     Completing the uric acid degradation pathway through phylogenetic
            comparison of whole genomes
  JOURNAL   Nat Chem Biol 2 (3), 144-148 (2006)
   PUBMED   16462750
  REMARK    GeneRIF: Identified as the gene encoding the enzyme catalyzing the
            third step of the pathway from uric acid to S-allantoin.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC147779.1 and DQ225767.1.
            
            On Sep 19, 2009 this sequence version replaced NM_001039678.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC147779.1, DQ225767.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849379
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-725               BC147779.1         1-725
            726-758             DQ225767.1         626-658
            759-762             DQ225767.1         660-663
            763-786             DQ225767.1         665-688
FEATURES             Location/Qualifiers
     source          1..786
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 86.87 cM"
     gene            1..786
                     /gene="Urad"
                     /gene_synonym="EG231903; Prhoxnb"
                     /note="ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5)
                     decarboxylase"
                     /db_xref="GeneID:231903"
                     /db_xref="MGI:MGI:3647519"
     exon            1..284
                     /gene="Urad"
                     /gene_synonym="EG231903; Prhoxnb"
                     /inference="alignment:Splign:2.1.0"
     CDS             110..646
                     /gene="Urad"
                     /gene_synonym="EG231903; Prhoxnb"
                     /EC_number="4.1.1.97"
                     /note="OHCU decarboxylase; parahox neighbor; parahox
                     cluster neighbor; ureidoimidazoline
                     (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase"
                     /codon_start=1
                     /product="2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline
                     decarboxylase"
                     /protein_id="NP_001034767.1"
                     /db_xref="CCDS:CCDS39399.1"
                     /db_xref="GeneID:231903"
                     /db_xref="MGI:MGI:3647519"
                     /translation="MDMVKVNSMDFGEFVDVFGNIVEKCPLIAAAVWSQRPFSGLEDL
                     ENHFFAFIDALPRSGQEGILRCHPDLAGRDLQQGTLTAESQREQSQAGLTSLDTDDRL
                     RLQQLNAQYRERFGFPFVLAARLSDRATVPRELARRLQCQPESELRTALGEVKKISHL
                     RLTDLLGAHSHSARVELP"
     exon            285..766
                     /gene="Urad"
                     /gene_synonym="EG231903; Prhoxnb"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccagcatgtg tgttcagcaa acacaaccca tgaggaggaa ttagctcact cgctcgatga
       61 gagcggacca caggcagggc agaacactgc ctccagtcca ggatcagcca tggacatggt
      121 gaaggtcaat tccatggact tcggagaatt tgtggatgtg tttgggaaca ttgttgagaa
      181 atgccctctg attgccgctg ctgtctggtc ccagcgtcca ttctctggct tggaagactt
      241 agaaaatcac ttttttgcct ttattgatgc tctcccgaga tcaggccagg aaggcatcct
      301 gcgttgtcac ccggacctag ctggccgtga tctgcaacag ggcacactca ctgctgagtc
      361 acagcgtgag cagagccaag caggtctcac tagcctagac accgacgaca ggctgcggct
      421 gcagcaactc aatgctcagt accgtgagcg cttcggcttt ccgttcgttc tggcagcgcg
      481 cctgagcgac cgtgccactg tgccccgaga gctagcccgc aggcttcagt gccagccgga
      541 atccgagctg cgcaccgccc tgggtgaagt gaagaagatc agccacctgc gcctgacaga
      601 tttgctcggt gcccactccc actccgccag ggtggaacta ccgtgagact ggggatcgga
      661 actccagcag gatgcctcag agaggggaca ccctgcgccc cggaatggct tgggcctgga
      721 aagacaattc atacacccac acaaaggaag tggagaattg aagcaaaaaa aaaaaaaaaa
      781 aaaaaa
//
