LOCUS       NM_025710               1313 bp    mRNA    linear   ROD 31-DEC-2024
DEFINITION  Mus musculus ubiquinol-cytochrome c reductase, Rieske iron-sulfur
            polypeptide 1 (Uqcrfs1), mRNA; nuclear gene for mitochondrial
            product.
ACCESSION   NM_025710
VERSION     NM_025710.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1313)
  AUTHORS   Vercellino,I. and Sazanov,L.A.
  TITLE     SCAF1 drives the compositional diversity of mammalian respirasomes
  JOURNAL   Nat Struct Mol Biol 31 (7), 1061-1071 (2024)
   PUBMED   38575788
REFERENCE   2  (bases 1 to 1313)
  AUTHORS   Waypa,G.B., Smith,K.A., Mungai,P.T., Dudley,V.J., Helmin,K.A.,
            Singer,B.D., Peek,C.B., Bass,J., Nelson,L., Shah,S.J., Ofman,G.,
            Wasserstrom,J.A., Muller,W.A., Misharin,A.V., Budinger,G.R.S.,
            Abdala-Valencia,H., Chandel,N.S., Dokic,D., Bartom,E., Zhang,S.,
            Tatekoshi,Y., Mahmoodzadeh,A., Ardehali,H., Thorp,E.B. and
            Schumacker,P.T.
  TITLE     Mitochondria regulate proliferation in adult cardiac myocytes
  JOURNAL   J Clin Invest 134 (13), e165482 (2024)
   PUBMED   38722697
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1313)
  AUTHORS   Cabello-Rivera,D., Ortega-Saenz,P., Gao,L., Munoz-Cabello,A.M.,
            Bonilla-Henao,V., Schumacker,P.T. and Lopez-Barneo,J.
  TITLE     Oxygen regulation of breathing is abolished in mitochondrial
            complex III-deficient arterial chemoreceptors
  JOURNAL   Proc Natl Acad Sci U S A 119 (39), e2202178119 (2022)
   PUBMED   36122208
REFERENCE   4  (bases 1 to 1313)
  AUTHORS   Vercellino,I. and Sazanov,L.A.
  TITLE     Structure and assembly of the mammalian mitochondrial supercomplex
            CIII2CIV
  JOURNAL   Nature 598 (7880), 364-367 (2021)
   PUBMED   34616041
REFERENCE   5  (bases 1 to 1313)
  AUTHORS   Yao,Y., Liu,Q., Adrianto,I., Wu,X., Glassbrook,J., Khalasawi,N.,
            Yin,C., Yi,Q., Dong,Z., Geissmann,F., Zhou,L. and Mi,Q.S.
  TITLE     Histone deacetylase 3 controls lung alveolar macrophage development
            and homeostasis
  JOURNAL   Nat Commun 11 (1), 3822 (2020)
   PUBMED   32732898
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1313)
  AUTHORS   Wiley,S.E., Murphy,A.N., Ross,S.A., van der Geer,P. and Dixon,J.E.
  TITLE     MitoNEET is an iron-containing outer mitochondrial membrane protein
            that regulates oxidative capacity
  JOURNAL   Proc Natl Acad Sci U S A 104 (13), 5318-5323 (2007)
   PUBMED   17376863
REFERENCE   7  (bases 1 to 1313)
  AUTHORS   Schilling,B., Murray,J., Yoo,C.B., Row,R.H., Cusack,M.P.,
            Capaldi,R.A. and Gibson,B.W.
  TITLE     Proteomic analysis of succinate dehydrogenase and
            ubiquinol-cytochrome c reductase (Complex II and III) isolated by
            immunoprecipitation from bovine and mouse heart mitochondria
  JOURNAL   Biochim Biophys Acta 1762 (2), 213-222 (2006)
   PUBMED   16120479
REFERENCE   8  (bases 1 to 1313)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   9  (bases 1 to 1313)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
REFERENCE   10 (bases 1 to 1313)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK014470.1.
            
            On Aug 5, 2008 this sequence version replaced NM_025710.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK014470.1, AK152391.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849377, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1313              AK014470.1         4-1316
FEATURES             Location/Qualifiers
     source          1..1313
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 13.23 cM"
     gene            1..1313
                     /gene="Uqcrfs1"
                     /gene_synonym="4430402G14Rik"
                     /note="ubiquinol-cytochrome c reductase, Rieske
                     iron-sulfur polypeptide 1"
                     /db_xref="GeneID:66694"
                     /db_xref="MGI:MGI:1913944"
     exon            1..283
                     /gene="Uqcrfs1"
                     /gene_synonym="4430402G14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            284..1313
                     /gene="Uqcrfs1"
                     /gene_synonym="4430402G14Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1150..1155
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Uqcrfs1"
                     /gene_synonym="4430402G14Rik"
                     /note="hexamer: AATAAA"
     regulatory      1158..1163
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Uqcrfs1"
                     /gene_synonym="4430402G14Rik"
                     /note="hexamer: ATTACA"
     polyA_site      1173
                     /gene="Uqcrfs1"
                     /gene_synonym="4430402G14Rik"
                     /note="major polyA site"
     polyA_site      1191
                     /gene="Uqcrfs1"
                     /gene_synonym="4430402G14Rik"
ORIGIN      
        1 ctcttcgggc cgtcgttcga acgaaaggtc gtccctgtga ccgacgaggt ggtttgagca
       61 gctgtcgcca tgttgtcggt cgccgcccgc tcgggcccgt tcgcgcccgt cctatcggcc
      121 acttcccgcg gggtggcggg cgcgctgcgt cctctgctgc aaggcgcggt gcccgccgcc
      181 tcggagccac ctgttctgga tgtgaagcga cccttcctgt gccgcgagtc cctgagtggc
      241 caggccgcag cccggccttt ggtggccacg gtgggcctga acgttcctgc ttctgtccgt
      301 ttttcccata cagatgtcaa ggtgcccgac ttctctgact atcgtcgtgc tgaagttctt
      361 gatagcacaa aatcttctaa agaaagcagt gaggctagaa aaggcttctc ttacctggta
      421 actgcaacta ctactgtggg tgttgcttat gcggccaaaa atgtggtctc ccagtttgtt
      481 tccagcatga gtgcttctgc tgacgtactg gccatgtcga agatcgagat caagttgtct
      541 gatatccctg aagggaagaa catggctttt aaatggagag gcaaacctct gtttgtgcgc
      601 catagaacca agaaggagat tgaccaggaa gctgcagtcg aagtgtccca gttaagggac
      661 ccacagcatg atttagatcg agtaaagaaa cctgaatggg ttattctgat aggtgtctgt
      721 actcatcttg gttgtgtacc cattgcaaac gcaggagatt ttggtggcta ttattgcccc
      781 tgccatgggt cacactatga cgcctctggc aggatcagga agggccctgc acctctcaac
      841 ctggaagtgc ctgcctacga gttcaccagt gatgatgtag ttgttgtggg ttagacacgt
      901 ggactcaggg cctaggtttc tgtcggtctt caggtcccct cagaagagtg gagagtaagc
      961 cttgtgtacg tctaggttgg ttgatttaaa atatttaaga attgttaata atgtattggc
     1021 aaacattaat gtgaagtaat tgaattcact gttaaatatt atcaagcatt agcataataa
     1081 aaccactgtt gaacatcatt agattcagtc atagacttga aaggtgcaat gtctttgata
     1141 gctaattcta ataaaacatt acagattgtt gtattggtgt tctcatctaa atttcttttc
     1201 gtatcttgaa cttgagaaaa ggtggggaca ttatttttca tctcaaagtg gatgggaaaa
     1261 tcattttgat atctaatatt tttctgtttt gatattaaac ctttcacagt tat
//
