LOCUS       NM_025650                436 bp    mRNA    linear   ROD 11-DEC-2024
DEFINITION  Mus musculus ubiquinol-cytochrome c reductase, complex III subunit
            XI (Uqcr11), mRNA.
ACCESSION   NM_025650
VERSION     NM_025650.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Vercellino,I. and Sazanov,L.A.
  TITLE     SCAF1 drives the compositional diversity of mammalian respirasomes
  JOURNAL   Nat Struct Mol Biol 31 (7), 1061-1071 (2024)
   PUBMED   38575788
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Ma,W., Tian,Y., Shi,L., Liang,J., Ouyang,Q., Li,J., Chen,H.,
            Sun,H., Ji,H., Liu,X., Huang,W., Gao,X., Jin,X., Wang,X., Liu,Y.,
            Yu,Y., Guo,X., Tian,Y., Yang,F., Li,F., Wang,N. and Cai,B.
  TITLE     N-Acetyltransferase 10 represses Uqcr11 and Uqcrb independently of
            ac4C modification to promote heart regeneration
  JOURNAL   Nat Commun 15 (1), 2137 (2024)
   PUBMED   38459019
  REMARK    GeneRIF: N-Acetyltransferase 10 represses Uqcr11 and Uqcrb
            independently of ac4C modification to promote heart regeneration.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 436)
  AUTHORS   Chong,D., Gu,Y., Zhang,T., Xu,Y., Bu,D., Chen,Z., Xu,N., Li,L.,
            Zhu,X., Wang,H., Li,Y., Zheng,F., Wang,D., Li,P., Xu,L., Hu,Z. and
            Li,C.
  TITLE     Neonatal ketone body elevation regulates postnatal heart
            development by promoting cardiomyocyte mitochondrial maturation and
            metabolic reprogramming
  JOURNAL   Cell Discov 8 (1), 106 (2022)
   PUBMED   36220812
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 436)
  AUTHORS   Vercellino,I. and Sazanov,L.A.
  TITLE     Structure and assembly of the mammalian mitochondrial supercomplex
            CIII2CIV
  JOURNAL   Nature 598 (7880), 364-367 (2021)
   PUBMED   34616041
REFERENCE   5  (bases 1 to 436)
  AUTHORS   Guo,R., Zong,S., Wu,M., Gu,J. and Yang,M.
  TITLE     Architecture of Human Mitochondrial Respiratory Megacomplex
            I2III2IV2
  JOURNAL   Cell 170 (6), 1247-1257 (2017)
   PUBMED   28844695
REFERENCE   6  (bases 1 to 436)
  AUTHORS   Dai,N., Zhao,L., Wrighting,D., Kramer,D., Majithia,A., Wang,Y.,
            Cracan,V., Borges-Rivera,D., Mootha,V.K., Nahrendorf,M.,
            Thorburn,D.R., Minichiello,L., Altshuler,D. and Avruch,J.
  TITLE     IGF2BP2/IMP2-Deficient mice resist obesity through enhanced
            translation of Ucp1 mRNA and Other mRNAs encoding mitochondrial
            proteins
  JOURNAL   Cell Metab 21 (4), 609-621 (2015)
   PUBMED   25863250
REFERENCE   7  (bases 1 to 436)
  AUTHORS   Xu,F., Ackerley,C., Maj,M.C., Addis,J.B., Levandovskiy,V., Lee,J.,
            Mackay,N., Cameron,J.M. and Robinson,B.H.
  TITLE     Disruption of a mitochondrial RNA-binding protein gene results in
            decreased cytochrome b expression and a marked reduction in
            ubiquinol-cytochrome c reductase activity in mouse heart
            mitochondria
  JOURNAL   Biochem J 416 (1), 15-26 (2008)
   PUBMED   18729827
REFERENCE   8  (bases 1 to 436)
  AUTHORS   Schilling,B., Murray,J., Yoo,C.B., Row,R.H., Cusack,M.P.,
            Capaldi,R.A. and Gibson,B.W.
  TITLE     Proteomic analysis of succinate dehydrogenase and
            ubiquinol-cytochrome c reductase (Complex II and III) isolated by
            immunoprecipitation from bovine and mouse heart mitochondria
  JOURNAL   Biochim Biophys Acta 1762 (2), 213-222 (2006)
   PUBMED   16120479
REFERENCE   9  (bases 1 to 436)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   10 (bases 1 to 436)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK003033.1 and BU529273.1.
            
            On Sep 6, 2006 this sequence version replaced NM_025650.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BU529273.1, AK003033.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-17                AK003033.1         11-27
            18-436              BU529273.1         19-437
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 39.72 cM"
     gene            1..436
                     /gene="Uqcr11"
                     /gene_synonym="0710008D09Rik; Uqcr"
                     /note="ubiquinol-cytochrome c reductase, complex III
                     subunit XI"
                     /db_xref="GeneID:66594"
                     /db_xref="MGI:MGI:1913844"
     exon            1..126
                     /gene="Uqcr11"
                     /gene_synonym="0710008D09Rik; Uqcr"
                     /inference="alignment:Splign:2.1.0"
     CDS             77..247
                     /gene="Uqcr11"
                     /gene_synonym="0710008D09Rik; Uqcr"
                     /note="ubiquinol-cytochrome c reductase subunit;
                     ubiquinol-cytochrome c reductase (6.4kD) subunit; complex
                     III subunit 10; complex III subunit XI;
                     ubiquinol-cytochrome c reductase complex 6.4 kDa protein"
                     /codon_start=1
                     /product="cytochrome b-c1 complex subunit 10"
                     /protein_id="NP_079926.1"
                     /db_xref="CCDS:CCDS35981.1"
                     /db_xref="GeneID:66594"
                     /db_xref="MGI:MGI:1913844"
                     /translation="MLSRFLGPRYRELARNWIPTAGMWGTVGAVGLVWATDWRLILDW
                     VPYINGKFKKDD"
     exon            127..277
                     /gene="Uqcr11"
                     /gene_synonym="0710008D09Rik; Uqcr"
                     /inference="alignment:Splign:2.1.0"
     exon            278..436
                     /gene="Uqcr11"
                     /gene_synonym="0710008D09Rik; Uqcr"
                     /inference="alignment:Splign:2.1.0"
     regulatory      411..416
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Uqcr11"
                     /gene_synonym="0710008D09Rik; Uqcr"
                     /note="hexamer: ATTAAA"
     polyA_site      436
                     /gene="Uqcr11"
                     /gene_synonym="0710008D09Rik; Uqcr"
                     /note="major polyA site"
ORIGIN      
        1 gcgctatacg tctgcacatg cgtagtgctc cagggcagcg gaacggggtg accctgagta
       61 ttgagaccct gcagcgatgc tgagcaggtt tctaggcccg cgctaccggg aactggccag
      121 aaactggatt cccacagccg gcatgtgggg cactgtgggt gccgtgggac tggtgtgggc
      181 cacggactgg cggctgatcc tggactgggt gccttacatc aacggcaagt ttaagaagga
      241 cgattaggca gcccctcccc caccacaggc ctcgatggta ccatgtgccg aggcctcaga
      301 cacagcgtag tcctgtggaa gacactgagg aagctggaca ctggagaggt ctgcaccgct
      361 cagggagctt ccatgttgac agacactagg gctgccttga tgggtgcagc attaaacctt
      421 attcttatgc cttgga
//
