LOCUS       NM_197979                441 bp    mRNA    linear   ROD 11-DEC-2024
DEFINITION  Mus musculus ubiquinol-cytochrome c reductase, complex III subunit
            X (Uqcr10), transcript variant 1, mRNA.
ACCESSION   NM_197979
VERSION     NM_197979.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Vercellino,I. and Sazanov,L.A.
  TITLE     SCAF1 drives the compositional diversity of mammalian respirasomes
  JOURNAL   Nat Struct Mol Biol 31 (7), 1061-1071 (2024)
   PUBMED   38575788
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 441)
  AUTHORS   Vercellino,I. and Sazanov,L.A.
  TITLE     Structure and assembly of the mammalian mitochondrial supercomplex
            CIII2CIV
  JOURNAL   Nature 598 (7880), 364-367 (2021)
   PUBMED   34616041
REFERENCE   4  (bases 1 to 441)
  AUTHORS   Guo,R., Zong,S., Wu,M., Gu,J. and Yang,M.
  TITLE     Architecture of Human Mitochondrial Respiratory Megacomplex
            I2III2IV2
  JOURNAL   Cell 170 (6), 1247-1257 (2017)
   PUBMED   28844695
REFERENCE   5  (bases 1 to 441)
  AUTHORS   Poche,R.A., Zhang,M., Rueda,E.M., Tong,X., McElwee,M.L., Wong,L.,
            Hsu,C.W., Dejosez,M., Burns,A.R., Fox,D.A., Martin,J.F., Zwaka,T.P.
            and Dickinson,M.E.
  TITLE     RONIN Is an Essential Transcriptional Regulator of Genes Required
            for Mitochondrial Function in the Developing Retina
  JOURNAL   Cell Rep 14 (7), 1684-1697 (2016)
   PUBMED   26876175
REFERENCE   6  (bases 1 to 441)
  AUTHORS   Schilling,B., Murray,J., Yoo,C.B., Row,R.H., Cusack,M.P.,
            Capaldi,R.A. and Gibson,B.W.
  TITLE     Proteomic analysis of succinate dehydrogenase and
            ubiquinol-cytochrome c reductase (Complex II and III) isolated by
            immunoprecipitation from bovine and mouse heart mitochondria
  JOURNAL   Biochim Biophys Acta 1762 (2), 213-222 (2006)
   PUBMED   16120479
REFERENCE   7  (bases 1 to 441)
  AUTHORS   Lin,Q., Donahue,S.L., Moore-Jarrett,T., Cao,S., Osipovich,A.B. and
            Ruley,H.E.
  TITLE     Mutagenesis of diploid mammalian genes by gene entrapment
  JOURNAL   Nucleic Acids Res 34 (20), e139 (2006)
   PUBMED   17062627
REFERENCE   8  (bases 1 to 441)
  AUTHORS   Osipovich,A.B., Singh,A. and Ruley,H.E.
  TITLE     Post-entrapment genome engineering: first exon size does not affect
            the expression of fusion transcripts generated by gene entrapment
  JOURNAL   Genome Res 15 (3), 428-435 (2005)
   PUBMED   15741512
REFERENCE   9  (bases 1 to 441)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   10 (bases 1 to 441)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB599515.1, BC100591.1 and AW985484.1.
            
            On May 2, 2018 this sequence version replaced NM_197979.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AW985484.1, CB599515.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10                CB599515.1         4-13
            11-434              BC100591.1         1-424
            435-441             AW985484.1         403-409
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 2.96 cM"
     gene            1..441
                     /gene="Uqcr10"
                     /gene_synonym="1110020P15Rik; Ucrc"
                     /note="ubiquinol-cytochrome c reductase, complex III
                     subunit X"
                     /db_xref="GeneID:66152"
                     /db_xref="MGI:MGI:1913402"
     exon            1..188
                     /gene="Uqcr10"
                     /gene_synonym="1110020P15Rik; Ucrc"
                     /inference="alignment:Splign:2.1.0"
     CDS             39..233
                     /gene="Uqcr10"
                     /gene_synonym="1110020P15Rik; Ucrc"
                     /note="isoform 1 is encoded by transcript variant 1;
                     ubiquinol-cytochrome c reductase complex protein;
                     cytochrome b-c1 complex subunit 9; ubiquinol-cytochrome c
                     reductase complex (7.2 kD); complex III subunit 9; complex
                     III subunit X; cytochrome c1 non-heme 7 kDa protein;
                     ubiquinol-cytochrome c reductase complex 7.2 kDa protein"
                     /codon_start=1
                     /product="cytochrome b-c1 complex subunit 9 isoform 1"
                     /protein_id="NP_932096.1"
                     /db_xref="CCDS:CCDS36098.1"
                     /db_xref="GeneID:66152"
                     /db_xref="MGI:MGI:1913402"
                     /translation="MSSPTIPSRLYSLLFRRTSTFALTIAVGALFFERAFDQGADAIY
                     EHINEGKLWKHIKHKYENKE"
     exon            189..441
                     /gene="Uqcr10"
                     /gene_synonym="1110020P15Rik; Ucrc"
                     /inference="alignment:Splign:2.1.0"
     regulatory      413..418
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Uqcr10"
                     /gene_synonym="1110020P15Rik; Ucrc"
                     /note="hexamer: AATAAA"
     polyA_site      436
                     /gene="Uqcr10"
                     /gene_synonym="1110020P15Rik; Ucrc"
                     /note="major polyA site"
ORIGIN      
        1 acgcaagcgc agtggcgcga gttcggcagt gaggcaacat gtcgtcgccg acgatccctt
       61 cgcgcctgta ctccttgctg ttccgcagaa cttccacctt tgccctcacc atcgcagtgg
      121 gcgccctgtt cttcgagcga gccttcgatc agggcgcaga cgcgatctac gagcacatca
      181 acgaggggaa actgtggaaa catataaagc acaagtatga gaacaaggag taacaccctg
      241 cccctgtggg acccgaagga acagtcgccg gtcagctgtt tgcctggagt tggggcctca
      301 gcctaaggat gagtttcaag ttgccgttca ccgaccgcca gtgtgtgggc aagctatggc
      361 tccactgtac aaacagactc acttctgctg tgtttgagta cagctgtcag caaataaatg
      421 caaagtgctc atgagaccgg c
//
