LOCUS       NM_001135567             748 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus ubiquinol-cytochrome c reductase complex assembly
            factor 6 (Uqcc6), transcript variant 1, mRNA.
ACCESSION   NM_001135567 XM_001476167 XM_985039
VERSION     NM_001135567.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 748)
  AUTHORS   Lanfranchi,M., Yandiev,S., Meyer-Dilhet,G., Ellouze,S.,
            Kerkhofs,M., Dos Reis,R., Garcia,A., Blondet,C., Amar,A.,
            Kneppers,A., Polveche,H., Plassard,D., Foretz,M., Viollet,B.,
            Sakamoto,K., Mounier,R., Bourgeois,C.F., Raineteau,O., Goillot,E.
            and Courchet,J.
  TITLE     The AMPK-related kinase NUAK1 controls cortical axons branching by
            locally modulating mitochondrial metabolic functions
  JOURNAL   Nat Commun 15 (1), 2487 (2024)
   PUBMED   38514619
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 748)
  AUTHORS   Liang,C., Zhang,S., Robinson,D., Ploeg,M.V., Wilson,R., Nah,J.,
            Taylor,D., Beh,S., Lim,R., Sun,L., Muoio,D.M., Stroud,D.A. and
            Ho,L.
  TITLE     Mitochondrial microproteins link metabolic cues to respiratory
            chain biogenesis
  JOURNAL   Cell Rep 40 (7), 111204 (2022)
   PUBMED   35977508
REFERENCE   3  (bases 1 to 748)
  AUTHORS   Zhang,S., Reljic,B., Liang,C., Kerouanton,B., Francisco,J.C.,
            Peh,J.H., Mary,C., Jagannathan,N.S., Olexiouk,V., Tang,C.,
            Fidelito,G., Nama,S., Cheng,R.K., Wee,C.L., Wang,L.C., Duek
            Roggli,P., Sampath,P., Lane,L., Petretto,E., Sobota,R.M.,
            Jesuthasan,S., Tucker-Kellogg,L., Reversade,B., Menschaert,G.,
            Sun,L., Stroud,D.A. and Ho,L.
  TITLE     Mitochondrial peptide BRAWNIN is essential for vertebrate
            respiratory complex III assembly
  JOURNAL   Nat Commun 11 (1), 1312 (2020)
   PUBMED   32161263
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 748)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC152980.2 and AK004515.1.
            
            On or before Oct 2, 2008 this sequence version replaced
            XM_001476167.1, XM_985039.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript. All three variants encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CO043219.1, AK045413.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164133, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-139               AC152980.2         87347-87485
            140-745             AK004515.1         2-607
            746-748             AC152980.2         90722-90724
FEATURES             Location/Qualifiers
     source          1..748
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 39.72 cM"
     gene            1..748
                     /gene="Uqcc6"
                     /gene_synonym="1190007I07Rik; Brawnin"
                     /note="ubiquinol-cytochrome c reductase complex assembly
                     factor 6"
                     /db_xref="GeneID:544717"
                     /db_xref="MGI:MGI:3698433"
     exon            1..264
                     /gene="Uqcc6"
                     /gene_synonym="1190007I07Rik; Brawnin"
                     /inference="alignment:Splign:2.1.0"
     exon            265..381
                     /gene="Uqcc6"
                     /gene_synonym="1190007I07Rik; Brawnin"
                     /inference="alignment:Splign:2.1.0"
     CDS             274..477
                     /gene="Uqcc6"
                     /gene_synonym="1190007I07Rik; Brawnin"
                     /note="uncharacterized protein C12orf73 homolog; protein
                     BRAWNIN"
                     /codon_start=1
                     /product="ubiquinol-cytochrome c reductase complex
                     assembly factor 6"
                     /protein_id="NP_001129039.1"
                     /db_xref="CCDS:CCDS48653.1"
                     /db_xref="GeneID:544717"
                     /db_xref="MGI:MGI:3698433"
                     /translation="MPGGVPWSAYLKMLSSSLLAMCAGAQVVHWYYRPDLTIPEIPPK
                     PGELKTELLGLKERRHEPHVSQQ"
     exon            382..748
                     /gene="Uqcc6"
                     /gene_synonym="1190007I07Rik; Brawnin"
                     /inference="alignment:Splign:2.1.0"
     regulatory      549..554
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Uqcc6"
                     /gene_synonym="1190007I07Rik; Brawnin"
                     /note="hexamer: AGTAAA"
     polyA_site      575
                     /gene="Uqcc6"
                     /gene_synonym="1190007I07Rik; Brawnin"
                     /note="major polyA site"
     regulatory      721..726
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Uqcc6"
                     /gene_synonym="1190007I07Rik; Brawnin"
                     /note="hexamer: AATAAA"
     polyA_site      744
                     /gene="Uqcc6"
                     /gene_synonym="1190007I07Rik; Brawnin"
                     /note="major polyA site"
ORIGIN      
        1 gcctgcgcga gtattgcctc cgctttccgc tccgtcgctg cgtcggaccc tgtactttgg
       61 ttcctgcccg ctggaggtcc gtcctggttc taaagcgacc ctgtgacctg tctccctgcg
      121 cgcgtgcact ccgcggtaca gtctcgtgcg cgcatagtcg tgggaaggaa cgaggggctc
      181 cagcgtctcc ctgagtggct gagggagcga ggaaccgccg agccctcctt cccctgctcg
      241 gcgggcgcag gctgcagcta gcagctctcc accatgcccg ggggcgtacc ctggtccgcc
      301 tacttgaaaa tgctttcctc cagcctcctg gccatgtgcg ccggggccca ggtggtgcat
      361 tggtactatc ggcctgacct gacaatacct gaaattccac caaagcctgg agaactcaaa
      421 acggagcttt tgggactgaa agagagacgc cacgaacctc atgtttcaca gcagtagaaa
      481 cttcaaaata acagctgtgc caagaattct gtgaataatg tttcaaatat gtattttaaa
      541 atttattaag taaaactact ttttaaaaca ccgaatttag ggggctcaat ggctcagagg
      601 ttaagagcac tgtctgctct tccagaggtc ctgtgttcaa ttcgcagcaa ccacttggtg
      661 gttcataacc atctatgagt tgtaccctgt tctggcccgc aggcagaatg ctgtatacat
      721 aataaatctt aatatttttt taaagata
//
