LOCUS       NM_001160356             847 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus ubiquinol-cytochrome c reductase complex assembly
            factor 3 (Uqcc3), mRNA.
ACCESSION   NM_001160356 XM_887080 XM_907845
VERSION     NM_001160356.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 847)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 847)
  AUTHORS   Zhang,G., Liu,B., Yang,Y., Xie,S., Chen,L., Luo,H., Zhong,J.,
            Wei,Y., Guo,F., Gan,J., Zhu,F., Xu,L., Li,Q., Shen,Y., Zhang,H.,
            Liu,Y., Li,R., Deng,H. and Yang,H.
  TITLE     Mitochondrial UQCC3 controls embryonic and tumor angiogenesis by
            regulating VEGF expression
  JOURNAL   iScience 26 (8), 107370 (2023)
   PUBMED   37539028
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 847)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 847)
  AUTHORS   Yang,Y., Zhang,G., Guo,F., Li,Q., Luo,H., Shu,Y., Shen,Y., Gan,J.,
            Xu,L. and Yang,H.
  TITLE     Mitochondrial UQCC3 Modulates Hypoxia Adaptation by Orchestrating
            OXPHOS and Glycolysis in Hepatocellular Carcinoma
  JOURNAL   Cell Rep 33 (5), 108340 (2020)
   PUBMED   33147459
REFERENCE   5  (bases 1 to 847)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
REFERENCE   6  (bases 1 to 847)
  AUTHORS   Jiang,H.Y., Jiang,L. and Wek,R.C.
  TITLE     The eukaryotic initiation factor-2 kinase pathway facilitates
            differential GADD45a expression in response to environmental stress
  JOURNAL   J Biol Chem 282 (6), 3755-3765 (2007)
   PUBMED   17170114
  REMARK    GeneRIF: The eIF2 kinase pathway induces both pro-survival and
            pro-apoptotic pathways.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC129217.3, AK132116.1 and BQ174007.1.
            
            On or before May 22, 2009 this sequence version replaced
            XM_907845.2, XM_887080.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AV166990.2, AY941793.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10                AC129217.3         113723-113732       c
            11-828              AK132116.1         2-819
            829-847             BQ174007.1         1-19                c
FEATURES             Location/Qualifiers
     source          1..847
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 5.9 cM"
     gene            1..847
                     /gene="Uqcc3"
                     /gene_synonym="Cbp4"
                     /note="ubiquinol-cytochrome c reductase complex assembly
                     factor 3"
                     /db_xref="GeneID:107197"
                     /db_xref="MGI:MGI:2147553"
     exon            1..228
                     /gene="Uqcc3"
                     /gene_synonym="Cbp4"
                     /inference="alignment:Splign:2.1.0"
     CDS             109..378
                     /gene="Uqcc3"
                     /gene_synonym="Cbp4"
                     /note="UPF0723 protein C11orf83 homolog"
                     /codon_start=1
                     /product="ubiquinol-cytochrome-c reductase complex
                     assembly factor 3"
                     /protein_id="NP_001153828.1"
                     /db_xref="CCDS:CCDS50383.1"
                     /db_xref="GeneID:107197"
                     /db_xref="MGI:MGI:2147553"
                     /translation="MEVARKALVAVAVLGGGAGVGSILFALVTPGELQKQSMLQEMPE
                     RDSRRRDEAVRTTELVMATLKDAAATKENVAWRRNWTVSGDGRSA"
     exon            229..831
                     /gene="Uqcc3"
                     /gene_synonym="Cbp4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      553..558
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Uqcc3"
                     /gene_synonym="Cbp4"
                     /note="hexamer: AATAAA"
     polyA_site      580
                     /gene="Uqcc3"
                     /gene_synonym="Cbp4"
                     /note="major polyA site"
     polyA_site      767
                     /gene="Uqcc3"
                     /gene_synonym="Cbp4"
                     /note="major polyA site"
     regulatory      809..814
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Uqcc3"
                     /gene_synonym="Cbp4"
                     /note="hexamer: AATGAA"
     polyA_site      831
                     /gene="Uqcc3"
                     /gene_synonym="Cbp4"
                     /note="major polyA site"
ORIGIN      
        1 cccctctcct aggtcgctct agcccgcata gggagcggtg agatgtcatg gcttccttct
       61 aggctgcggg aggaagcgga cggcacctct tttgtagtgt aatccgccat ggaggtggct
      121 cgtaaagcac ttgtggcagt tgcagtgcta ggcgggggag ctggcgtggg ttctattctg
      181 tttgctcttg tgaccccagg agaactacag aagcagtcga tgctgcagga gatgccggaa
      241 agggactcgc ggcgcaggga cgaagcagtc aggaccacgg aactggtgat ggctaccctg
      301 aaggacgccg cagccacgaa ggagaacgtg gcctggagga gaaactggac agttagcggg
      361 gatggcaggt cagcatgaca ccagagctcg cccgtggtca cgggaacctg taaggctcct
      421 ttcttggtgc tccggacatg gagtcgggag atacaccagg actctctcca agtcactggg
      481 aactgcggtt gggggaacgc ctttaaagag cacatcgcct gacagggtcg gatgtgtgga
      541 accaacggaa ctaataaatg cagttcatcc attaagtgga tttcgcagct ggacatctaa
      601 tgcttagaga gctgtgagag agcgcaatgt gcgctgaaga cctaggcaac tgcatgccat
      661 cctacccctg agagttctta agtccaataa gttttctgac tattcaaaat aggtcatatg
      721 atctaagttt gcttctgcaa ctgttgggta aaagacttta ggaaaaagtc tggttttgta
      781 tgtcacaatg tgtgttgtgt gaatgaaaaa tgaaagtcgg aagtcaccga aaaaaaaaaa
      841 aaaaaaa
//
