LOCUS       NM_026063                473 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus ubiquinol-cytochrome c reductase complex assembly
            factor 2 (Uqcc2), transcript variant 1, mRNA.
ACCESSION   NM_026063
VERSION     NM_026063.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Zurkirchen,L., Varum,S., Giger,S., Klug,A., Hausel,J., Bossart,R.,
            Zemke,M., Cantu,C., Atak,Z.K., Zamboni,N., Basler,K. and Sommer,L.
  TITLE     Yin Yang 1 sustains biosynthetic demands during brain development
            in a stage-specific manner
  JOURNAL   Nat Commun 10 (1), 2192 (2019)
   PUBMED   31097699
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Cambier,L., Rassam,P., Chabi,B., Mezghenna,K., Gross,R., Eveno,E.,
            Auffray,C., Wrutniak-Cabello,C., Lajoix,A.D. and Pomies,P.
  TITLE     M19 modulates skeletal muscle differentiation and insulin secretion
            in pancreatic beta-cells through modulation of respiratory chain
            activity
  JOURNAL   PLoS One 7 (2), e31815 (2012)
   PUBMED   22363741
  REMARK    GeneRIF: The function of M19, a novel mitochondrial nucleoid
            protein, is characterized in muscle and pancreatic beta-cells.
REFERENCE   3  (bases 1 to 473)
  AUTHORS   Sumitani,M., Kasashima,K., Ohta,E., Kang,D. and Endo,H.
  TITLE     Association of a novel mitochondrial protein M19 with mitochondrial
            nucleoids
  JOURNAL   J Biochem 146 (5), 725-732 (2009)
   PUBMED   19643811
  REMARK    GeneRIF: M19 associates with the nucleoid and likely regulates the
            organization and metabolism of mtDNA.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK013521.1.
            
            On Apr 5, 2007 this sequence version replaced NM_026063.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK013521.1, BC030629.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-473               AK013521.1         5-477
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 13.75 cM"
     gene            1..473
                     /gene="Uqcc2"
                     /gene_synonym="2900010M23Rik; Cbp6; M19; Mnf1"
                     /note="ubiquinol-cytochrome c reductase complex assembly
                     factor 2"
                     /db_xref="GeneID:67267"
                     /db_xref="MGI:MGI:1914517"
     exon            1..152
                     /gene="Uqcc2"
                     /gene_synonym="2900010M23Rik; Cbp6; M19; Mnf1"
                     /inference="alignment:Splign:2.1.0"
     CDS             15..425
                     /gene="Uqcc2"
                     /gene_synonym="2900010M23Rik; Cbp6; M19; Mnf1"
                     /EC_number="2.7.4.21"
                     /note="isoform 1 is encoded by transcript variant 1;
                     mitochondrial protein M19; mitochondrial nucleoid factor
                     1"
                     /codon_start=1
                     /product="ubiquinol-cytochrome c reductase complex
                     assembly factor 2 isoform 1"
                     /protein_id="NP_080339.1"
                     /db_xref="CCDS:CCDS28561.1"
                     /db_xref="GeneID:67267"
                     /db_xref="MGI:MGI:1914517"
                     /translation="MAALRYRRFLKLCEEWPVDETKRGRDLGAYLRQRVAQAFREGEN
                     TQIAEPEACDQMYESLARLHSNYYKHKYPRPRDTSFSGLSVEEYKLILSTDTLEEFQE
                     MNKSMWKKLQEKFAPTRPEEKHKAWTRVLSRPRT"
     exon            153..227
                     /gene="Uqcc2"
                     /gene_synonym="2900010M23Rik; Cbp6; M19; Mnf1"
                     /inference="alignment:Splign:2.1.0"
     exon            228..297
                     /gene="Uqcc2"
                     /gene_synonym="2900010M23Rik; Cbp6; M19; Mnf1"
                     /inference="alignment:Splign:2.1.0"
     exon            298..473
                     /gene="Uqcc2"
                     /gene_synonym="2900010M23Rik; Cbp6; M19; Mnf1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      447..452
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Uqcc2"
                     /gene_synonym="2900010M23Rik; Cbp6; M19; Mnf1"
                     /note="hexamer: AATAAA"
     polyA_site      470
                     /gene="Uqcc2"
                     /gene_synonym="2900010M23Rik; Cbp6; M19; Mnf1"
                     /note="major polyA site"
ORIGIN      
        1 aagcggggcc caagatggcc gctctccgct accggcgttt ccttaagctc tgtgaggaat
       61 ggccagtgga cgagaccaaa cggggccggg acttgggcgc ttacctgcgg cagcgggtag
      121 cgcaggcctt ccgggaggga gagaacaccc agattgcaga acccgaggcc tgtgatcaga
      181 tgtacgagag cttagcacga ctgcattcaa actactacaa gcacaagtac cctcgcccca
      241 gagacaccag cttcagtggc ctgtccgtgg aagagtacaa gctgatcctg tccacagaca
      301 ctttggaaga gttccaagag atgaataaga gcatgtggaa gaaactgcag gagaagtttg
      361 cgcccaccag gcctgaggag aagcacaagg cctggactcg ggtcctgtcc cgcccacgga
      421 cctgaccgtg gggtctgata ctcatcaata aaactgcctg gtttctccca ccc
//
