LOCUS       NM_175309               2036 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus uroplakin 3B (Upk3b), mRNA.
ACCESSION   NM_175309
VERSION     NM_175309.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2036)
  AUTHORS   Qiu,C., Martin,B.K., Welsh,I.C., Daza,R.M., Le,T.M., Huang,X.,
            Nichols,E.K., Taylor,M.L., Fulton,O., O'Day,D.R., Gomes,A.R.,
            Ilcisin,S., Srivatsan,S., Deng,X., Disteche,C.M., Noble,W.S.,
            Hamazaki,N., Moens,C.B., Kimelman,D., Cao,J., Schier,A.F.,
            Spielmann,M., Murray,S.A., Trapnell,C. and Shendure,J.
  TITLE     A single-cell time-lapse of mouse prenatal development from
            gastrula to birth
  JOURNAL   Nature 626 (8001), 1084-1093 (2024)
   PUBMED   38355799
REFERENCE   2  (bases 1 to 2036)
  AUTHORS   Han,X., Zhang,Z., He,L., Zhu,H., Li,Y., Pu,W., Han,M., Zhao,H.,
            Liu,K., Li,Y., Huang,X., Zhang,M., Jin,H., Lv,Z., Tang,J., Wang,J.,
            Sun,R., Fei,J., Tian,X., Duan,S., Wang,Q.D., Wang,L., He,B. and
            Zhou,B.
  TITLE     A suite of new Dre recombinase drivers markedly expands the ability
            to perform intersectional genetic targeting
  JOURNAL   Cell Stem Cell 28 (6), 1160-1176 (2021)
   PUBMED   33567267
REFERENCE   3  (bases 1 to 2036)
  AUTHORS   Christians,A., Weiss,A.C., Martens,H., Klopf,M.G., Hennies,I.,
            Haffner,D., Kispert,A. and Weber,R.G.
  TITLE     Inflammation-like changes in the urothelium of Lifr-deficient mice
            and LIFR-haploinsufficient humans with urinary tract anomalies
  JOURNAL   Hum Mol Genet 29 (7), 1192-1204 (2020)
   PUBMED   32179912
REFERENCE   4  (bases 1 to 2036)
  AUTHORS   Velecela,V., Torres-Cano,A., Garcia-Melero,A., Ramiro-Pareta,M.,
            Muller-Sanchez,C., Segarra-Mondejar,M., Chau,Y.Y.,
            Campos-Bonilla,B., Reina,M., Soriano,F.X., Hastie,N.D.,
            Martinez,F.O. and Martinez-Estrada,O.M.
  TITLE     Epicardial cell shape and maturation are regulated by Wt1 via
            transcriptional control of Bmp4
  JOURNAL   Development 146 (20) (2019)
   PUBMED   31624071
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2036)
  AUTHORS   Weiss,A.C., Bohnenpoll,T., Kurz,J., Blank,P., Airik,R.,
            Ludtke,T.H., Kleppa,M.J., Deuper,L., Kaiser,M., Mamo,T.M.,
            Costa,R., von Hahn,T., Trowe,M.O. and Kispert,A.
  TITLE     Delayed onset of smooth muscle cell differentiation leads to
            hydroureter formation in mice with conditional loss of the zinc
            finger transcription factor gene Gata2 in the ureteric mesenchyme
  JOURNAL   J Pathol 248 (4), 452-463 (2019)
   PUBMED   30916783
REFERENCE   6  (bases 1 to 2036)
  AUTHORS   Cain,J.E., Islam,E., Haxho,F., Blake,J. and Rosenblum,N.D.
  TITLE     GLI3 repressor controls functional development of the mouse ureter
  JOURNAL   J Clin Invest 121 (3), 1199-1206 (2011)
   PUBMED   21339645
REFERENCE   7  (bases 1 to 2036)
  AUTHORS   Drerup,J.M., Hayashi,K., Cui,H., Mettlach,G.L., Long,M.A.,
            Marvin,M., Sun,X., Goldberg,M.S., Lutter,M. and Bibb,J.A.
  TITLE     Attention-deficit/hyperactivity phenotype in mice lacking the
            cyclin-dependent kinase 5 cofactor p35
  JOURNAL   Biol Psychiatry 68 (12), 1163-1171 (2010)
   PUBMED   20832057
REFERENCE   8  (bases 1 to 2036)
  AUTHORS   Yu,Z., Mannik,J., Soto,A., Lin,K.K. and Andersen,B.
  TITLE     The epidermal differentiation-associated Grainyhead gene Get1/Grhl3
            also regulates urothelial differentiation
  JOURNAL   EMBO J 28 (13), 1890-1903 (2009)
   PUBMED   19494835
REFERENCE   9  (bases 1 to 2036)
  AUTHORS   Cheng,W., Jacobs,W.B., Zhang,J.J., Moro,A., Park,J.H., Kushida,M.,
            Qiu,W., Mills,A.A. and Kim,P.C.
  TITLE     DeltaNp63 plays an anti-apoptotic role in ventral bladder
            development
  JOURNAL   Development 133 (23), 4783-4792 (2006)
   PUBMED   17079275
REFERENCE   10 (bases 1 to 2036)
  AUTHORS   Deng,F.M., Liang,F.X., Tu,L., Resing,K.A., Hu,P., Supino,M.,
            Hu,C.C., Zhou,G., Ding,M., Kreibich,G. and Sun,T.T.
  TITLE     Uroplakin IIIb, a urothelial differentiation marker, dimerizes with
            uroplakin Ib as an early step of urothelial plaque assembly
  JOURNAL   J Cell Biol 159 (4), 685-694 (2002)
   PUBMED   12446744
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK052525.1.
            
            On Apr 6, 2007 this sequence version replaced NM_175309.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK052525.1, AK157647.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849376
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2036              AK052525.1         3-2038
FEATURES             Location/Qualifiers
     source          1..2036
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 75.7 cM"
     gene            1..2036
                     /gene="Upk3b"
                     /gene_synonym="P35; PMS2L14; UpIIIb"
                     /note="uroplakin 3B"
                     /db_xref="GeneID:100647"
                     /db_xref="MGI:MGI:2140882"
     exon            1..391
                     /gene="Upk3b"
                     /gene_synonym="P35; PMS2L14; UpIIIb"
                     /inference="alignment:Splign:2.1.0"
     CDS             307..1137
                     /gene="Upk3b"
                     /gene_synonym="P35; PMS2L14; UpIIIb"
                     /note="uroplakin-3b; uroplakin IIIb; UP3b"
                     /codon_start=1
                     /product="uroplakin-3b precursor"
                     /protein_id="NP_780518.1"
                     /db_xref="CCDS:CCDS19750.1"
                     /db_xref="GeneID:100647"
                     /db_xref="MGI:MGI:2140882"
                     /translation="MVRTRWQPHPPPPLLLLVLVWLPQSLSLDLIAYVPQITAWDLEG
                     KITATTFSLEQPRCVFDEHVSTKDTIWLVVAFSNASRDFQNPQTAAKIPTFPQLLTDG
                     HYMTLPLSLDQLPCEDLTGGSGGVPVLRVGNDFGCYQRPYCNAPLPSQGPYSVKFLVM
                     DAAGPPKAETKWSNPIYLHQGKNPNSIDTWPGRRSGCMIVITSILSALAGLLLLAFLA
                     ASTTRFSSLWWPEEAPEQLRIGSFMGKRYMTHHIPPSEAATLPVGCEPGLDPLPSLSP
                     "
     exon            392..541
                     /gene="Upk3b"
                     /gene_synonym="P35; PMS2L14; UpIIIb"
                     /inference="alignment:Splign:2.1.0"
     exon            542..767
                     /gene="Upk3b"
                     /gene_synonym="P35; PMS2L14; UpIIIb"
                     /inference="alignment:Splign:2.1.0"
     exon            768..847
                     /gene="Upk3b"
                     /gene_synonym="P35; PMS2L14; UpIIIb"
                     /inference="alignment:Splign:2.1.0"
     exon            848..977
                     /gene="Upk3b"
                     /gene_synonym="P35; PMS2L14; UpIIIb"
                     /inference="alignment:Splign:2.1.0"
     exon            978..2036
                     /gene="Upk3b"
                     /gene_synonym="P35; PMS2L14; UpIIIb"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agggagtaag gtggtaccac aatttagaca tcagctttgg gatggaggtg actggggggt
       61 cacgtgaagg ccaaccctaa atggctcctc tcccttagtt ctggagtggg gcccctgttc
      121 aggagcccac tgagcccctc cctggggtgg gctgggagca gggaggggtg agctcatagg
      181 ttcaggtctt tcctgttctc ctggcagtcc aagtgaccag caactgtagg ccagaggtgt
      241 cggaggtggg gtgagacagg accagcccct aagcctggtc aggcctgatc aagtgctgtg
      301 gcagtcatgg tgcgaacgcg gtggcagcct caccctccgc cgcccctgct tctcctggtg
      361 ctcgtgtggc tcccccaaag cctgagtcta gacctgattg cctacgtgcc gcagataaca
      421 gcctgggacc tggaagggaa gatcacagcc actacattct ctctggagca gcctcggtgc
      481 gtctttgatg agcatgtctc aactaaggac accatctggc tagtggtggc tttcagcaat
      541 gcctccaggg actttcagaa cccacagact gctgctaaga tcccgacctt cccacagctg
      601 ctgactgacg gccactatat gacattaccc ctgtccctgg atcagctgcc atgtgaggac
      661 ctgaccggtg gcagtggagg tgtccccgtg cttcgggtgg gcaatgattt tggctgttac
      721 cagcgaccct attgcaacgc ccccctcccc agccagggcc cttacagtgt gaagttcctt
      781 gtaatggatg ccgccggccc acccaaggct gagacgaagt ggtccaaccc catttatctc
      841 caccaaggaa agaatcccaa ctccattgac acatggcctg gccgacggag cggctgtatg
      901 atcgtcataa cttccatcct ctctgccctg gccggcctct tgctcctggc tttcctggca
      961 gcttccacta cgcgtttctc cagcctgtgg tggcccgagg aagctcctga gcagctgcgg
     1021 attggctcct tcatgggaaa acgttacatg actcaccata tcccccccag cgaagctgcc
     1081 acactgccgg tgggctgcga gcctggcctg gacccccttc ccagtctcag cccgtagcct
     1141 ggtctctgta gcttgggcct ggggtgaggg gcagagagca gatgtgcagg tcctgtgggg
     1201 tgggggtggg ggtcttgcat ctgcacagcc ccttctatct gcctggctgt tttatttctg
     1261 cttttgcccc tcactaggct ctgtctgtaa gtatgcttgc aggtggtcaa ggtcagcttg
     1321 gccaacttaa cctccttcat gtaaggctag aggaggtggc cagttcatct tcaccttagc
     1381 cagacttcag agaacgcagc aggacggttg acacaagcta cgatccccac acttgggagg
     1441 ctgaagtagg agggtcatgt acttcaggct agtctgggat atctggcagg agcaggtctc
     1501 aaatgaaaca aaccaaaaca aaacaaaaac acacaacccg gtaggcagcc ttgttgggca
     1561 gtcagtaggt tgggctgggc ccatcatgag ttatatgagg ttcaggccac cttccgtctg
     1621 acccaacaac caggggtggg gtgcagttac acaaatacca ctttcgtccc cctcgctctt
     1681 tctgaggatg ggtctcacca agtgtactgg ttagagagtg taaatggcta ttaatgacag
     1741 tcggctacct agcccagccc ctgtgcacac agagagatgg ttctgcacac ttctcggctc
     1801 actcagcatc atttattgtg catctggcat tctgcaccac atacagtgtt agacacggcc
     1861 tcggggaaag ctgattgtaa ctttggagga ctctaccttg ctttgaatcg cagactgaca
     1921 cctgtccaga tgtgggatct attactgctg gggagatgtc atgctctcaa actatcctcg
     1981 gagtcactct cccaattacc atagtgggct ctttgagacc cactgtacac tcgatc
//
