LOCUS       NM_013702               2109 bp    mRNA    linear   ROD 29-AUG-2023
DEFINITION  Mus musculus UNC homeobox (Uncx), mRNA.
ACCESSION   NM_013702 XM_001000841
VERSION     NM_013702.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2109)
  AUTHORS   Qu F, Li W, Xu J, Zhang R, Ke J, Ren X, Meng X, Qin L, Zhang J, Lu
            F, Zhou X, Luo X, Zhang Z, Wang M, Wu G, Pei D, Chen J, Cui G, Suo
            S and Peng G.
  TITLE     Three-dimensional molecular architecture of mouse organogenesis
  JOURNAL   Nat Commun 14 (1), 4599 (2023)
   PUBMED   37524711
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2109)
  AUTHORS   Hatakeyama Y, Saito N, Mii Y, Takada R, Shinozuka T, Takemoto T,
            Naoki H and Takada S.
  TITLE     Intercellular exchange of Wnt ligands reduces cell population
            heterogeneity during embryogenesis
  JOURNAL   Nat Commun 14 (1), 1924 (2023)
   PUBMED   37024462
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2109)
  AUTHORS   Weiss AC, Blank E, Bohnenpoll T, Kleppa MJ, Rivera-Reyes R, Taketo
            MM, Trowe MO and Kispert A.
  TITLE     Permissive ureter specification by TBX18-mediated repression of
            metanephric gene expression
  JOURNAL   Development 150 (6) (2023)
   PUBMED   36960826
REFERENCE   4  (bases 1 to 2109)
  AUTHORS   Genuth NR, Shi Z, Kunimoto K, Hung V, Xu AF, Kerr CH, Tiu GC,
            Oses-Prieto JA, Salomon-Shulman REA, Axelrod JD, Burlingame AL, Loh
            KM and Barna M.
  TITLE     A stem cell roadmap of ribosome heterogeneity reveals a function
            for RPL10A in mesoderm production
  JOURNAL   Nat Commun 13 (1), 5491 (2022)
   PUBMED   36123354
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2109)
  AUTHORS   Filova I, Pysanenko K, Tavakoli M, Vochyanova S, Dvorakova M,
            Bohuslavova R, Smolik O, Fabriciova V, Hrabalova P, Benesova S,
            Valihrach L, Cerny J, Yamoah EN, Syka J, Fritzsch B and Pavlinkova
            G.
  TITLE     ISL1 is necessary for auditory neuron development and contributes
            toward tonotopic organization
  JOURNAL   Proc Natl Acad Sci U S A 119 (37), e2207433119 (2022)
   PUBMED   36074819
REFERENCE   6  (bases 1 to 2109)
  AUTHORS   Evrard YA, Lun Y, Aulehla A, Gan L and Johnson RL.
  TITLE     lunatic fringe is an essential mediator of somite segmentation and
            patterning
  JOURNAL   Nature 394 (6691), 377-381 (1998)
   PUBMED   9690473
REFERENCE   7  (bases 1 to 2109)
  AUTHORS   Zhang N and Gridley T.
  TITLE     Defects in somite formation in lunatic fringe-deficient mice
  JOURNAL   Nature 394 (6691), 374-377 (1998)
   PUBMED   9690472
REFERENCE   8  (bases 1 to 2109)
  AUTHORS   Mansouri A, Yokota Y, Wehr R, Copeland NG, Jenkins NA and Gruss P.
  TITLE     Paired-related murine homeobox gene expressed in the developing
            sclerotome, kidney, and nervous system
  JOURNAL   Dev Dyn 210 (1), 53-65 (1997)
   PUBMED   9286595
REFERENCE   9  (bases 1 to 2109)
  AUTHORS   Rovescalli AC, Asoh S and Nirenberg M.
  TITLE     Cloning and characterization of four murine homeobox genes
  JOURNAL   Proc Natl Acad Sci U S A 93 (20), 10691-10696 (1996)
   PUBMED   8855241
  REMARK    Erratum:[Proc Natl Acad Sci U S A 1996 Dec 24;93(26):15522]
REFERENCE   10 (bases 1 to 2109)
  AUTHORS   Bulleit RF, Lin X and Jeppi JV.
  TITLE     A novel gene selectively expressed in the cerebellum
  JOURNAL   Neurosci Lett 209 (2), 93-96 (1996)
   PUBMED   8761990
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK082472.1, BC051973.1, AV120135.1 and AJ001116.1.
            
            [WARNING] On Nov 16, 2023 this sequence was replaced by
            NM_013702.4.
            
            On Apr 19, 2007 this sequence version replaced NM_013702.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF247550.1, Z96107.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849385, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-38                AK082472.1         2-39
            39-1993             BC051973.1         1-1955
            1994-2006           AV120135.1         94-106
            2007-2109           AJ001116.1         1947-2049
FEATURES             Location/Qualifiers
     source          1..2109
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 78.75 cM"
     gene            1..2109
                     /gene="Uncx"
                     /gene_synonym="Chx4; Uncx4.1"
                     /note="UNC homeobox"
                     /db_xref="GeneID:22255"
                     /db_xref="MGI:MGI:108013"
     exon            1..382
                     /gene="Uncx"
                     /gene_synonym="Chx4; Uncx4.1"
                     /inference="alignment:Splign:2.1.0"
     CDS             97..1689
                     /gene="Uncx"
                     /gene_synonym="Chx4; Uncx4.1"
                     /note="homeobox protein Uncx4.1; Unc4.1 homeobox"
                     /codon_start=1
                     /product="homeobox protein unc-4 homolog"
                     /protein_id="NP_038730.1"
                     /db_xref="CCDS:CCDS19813.1"
                     /db_xref="GeneID:22255"
                     /db_xref="MGI:MGI:108013"
                     /translation="MMDGRLLEHPHAQFGGSLGGVVGFPYPLGHHHVYELAGHQLQSA
                     AAAAAAASVPFSIDGLLSGSCAAAAASVVNPTPLLPAACGVAGESQPFKLADSGDPDK
                     ESPGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNR
                     RAKWRKKENTKKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKS
                     QSRHLHSPGGLSLHSAPSSDSDSGGGGLSPEPPEPPPPTAAAKGPGAHGSGIAGSAPV
                     PPGEPPAPGTCDPAFYPSQRSGAGSQPRLGRPADKDTVPCGPGAAATAGLPKASPFSV
                     ESLLSDSPPRRKATPANAAATAGLDFTPGLPCAPRTLIGKGHFLLYPITQPLGFLVPQ
                     AALKGGAGPELVPKDAPPAPPAPPAPPAQASFGTFPGPGGAADPAFARRSPEVVASPG
                     PPAPASFRDLTAAAAESGAGDCADVGTVCPAASPPPPLETSPGPGPRAPSPPGEPATC
                     GAAEPGAATGPSPPEGEEVDMD"
     exon            383..558
                     /gene="Uncx"
                     /gene_synonym="Chx4; Uncx4.1"
                     /inference="alignment:Splign:2.1.0"
     exon            559..2094
                     /gene="Uncx"
                     /gene_synonym="Chx4; Uncx4.1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2073..2078
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Uncx"
                     /gene_synonym="Chx4; Uncx4.1"
ORIGIN      
        1 aaagcggcgg agcgcgggcc gaagcatgtg tagggctccg ggcccctgtc cccgccgccg
       61 tccgcgcccc cgcgccccgc cagccccgcg cgcgagatga tggacggtcg cctcctggag
      121 cacccgcatg cccagttcgg gggctcgctg ggcggcgtgg tgggcttccc ctacccgctg
      181 ggccaccacc acgtgtacga gctggccggt caccagctgc agtcggccgc cgccgccgct
      241 gccgcggcct cggtgccctt ctccatcgac ggcctgctca gcggctcgtg cgctgcagcc
      301 gccgcctcgg tggtcaaccc cacgccgctg ctgccggctg cctgcggggt ggccggcgaa
      361 agccagccct tcaagcttgc agactcgggg gatccagaca aggagagccc cggctgcaaa
      421 cggagacgca cccgcaccaa ctttaccggc tggcagctgg aggagctgga gaaggcgttc
      481 aatgagagcc actacccgga cgtgtttatg cgcgaggcgc tggcgctgcg cctggacctg
      541 gtcgagtccc gagttcaggt ctggttccaa aatcgccggg ccaaatggag aaagaaggag
      601 aacaccaaaa agggccctgg ccggccggcc cacaactcgc acccgaccac gtgcagcggg
      661 gagcccatgg acccagagga gatcgctcgc aaggaactgg agaagatgga gaagaagaaa
      721 cgcaaacacg agaagaaact gctcaagagt cagagccgcc acctgcactc gcccggtggc
      781 ctgtccctgc acagcgcgcc cagctccgac agcgacagcg gtggcggagg cctgtctcca
      841 gagccacccg agccgccacc gccgaccgcc gcggccaagg gtcctggagc gcacggctct
      901 ggcatcgcgg gttccgctcc ggtacctcct ggcgagccac ccgcgcctgg cacctgcgat
      961 cccgccttct acccgagcca aagaagcggc gccggctcgc agccacggct aggtcgcccg
     1021 gcggacaagg acacggtccc ttgcgggcct ggagcggcgg cgactgcggg cctgcctaag
     1081 gctagcccgt tcagcgtgga gagcctgctg tccgactcgc caccgcgccg caaagccacc
     1141 ccagccaacg ctgcggccac tgcggggctg gacttcacgc cggggctgcc gtgtgcacct
     1201 cggaccctga ttggcaaggg ccacttcttg ctctacccca tcacgcagcc cctgggtttc
     1261 ctagtgccac aggcagcgct caagggcgga gcgggccctg aattggtgcc caaggacgcg
     1321 ccgcccgcgc cccccgcgcc ccccgcacca cccgcgcagg ccagtttcgg gaccttcccc
     1381 ggacctggtg gcgctgcgga cccggccttc gcccgtcgca gccctgaggt tgttgcctct
     1441 cccgggccac ccgctcccgc ttctttccgg gacctaacag cggcggctgc cgagagcggt
     1501 gccggggact gcgcggacgt ggggaccgtc tgccccgcgg cctcgccgcc cccacctctc
     1561 gaaacgtcgc ctggcccggg ccctagagcc cccagcccac ccggggagcc agccacttgc
     1621 ggcgccgctg agccgggcgc tgctacggga cccagccctc ccgagggcga ggaggtggac
     1681 atggactgag ctggggaccg cggctggaag atgcgcttag ccagtcgagc ccactcactc
     1741 agccccagac tcccaacgaa tcaggtgatc ggctcttaga gacattgctt ttccctcttg
     1801 ctttttgttt tcttcctttt attattattt ttaaaggcaa acgaaaacgc tgtgtcgatg
     1861 gggaccaagg cggcagctgc tggtcctggg gtgaggtccc ctcctccgga gggatcaaaa
     1921 aaccccatat cccctaacac acacacacac acacacacac acacacacac acacacacac
     1981 acacacacac acacaaaacc cacaacgaga atcctcagcc ttgtaaaatg caaaaatgtc
     2041 taagaatatt tatatatgta ccatttttta taaataaagc tgatcaaacg caaaaaaaaa
     2101 aaaaaaaaa
//
