LOCUS       NM_001293561            9320 bp    mRNA    linear   ROD 13-DEC-2024
DEFINITION  Mus musculus unc-5 netrin receptor C (Unc5c), transcript variant 1,
            mRNA.
ACCESSION   NM_001293561 XM_006501311
VERSION     NM_001293561.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 9320)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 9320)
  AUTHORS   Luo,P.M., Gu,X., Chaney,C., Carroll,T. and Cleaver,O.
  TITLE     Stromal netrin 1 coordinates renal arteriogenesis and mural cell
            differentiation
  JOURNAL   Development 150 (22) (2023)
   PUBMED   37823339
REFERENCE   3  (bases 1 to 9320)
  AUTHORS   Honeycutt,S.E., N'Guetta,P.Y., Hardesty,D.M., Xiong,Y.,
            Cooper,S.L., Stevenson,M.J. and O'Brien,L.L.
  TITLE     Netrin 1 directs vascular patterning and maturity in the developing
            kidney
  JOURNAL   Development 150 (22) (2023)
   PUBMED   37818607
REFERENCE   4  (bases 1 to 9320)
  AUTHORS   Prigge,C.L., Dembla,M., Sharma,A., El-Quessny,M., Kozlowski,C.,
            Paisley,C.E., Miltner,A.M., Johnson,T.M., Della Santina,L.,
            Feller,M.B. and Kay,J.N.
  TITLE     Rejection of inappropriate synaptic partners in mouse retina
            mediated by transcellular FLRT2-UNC5 signaling
  JOURNAL   Dev Cell 58 (20), 2080-2096 (2023)
   PUBMED   37557174
REFERENCE   5  (bases 1 to 9320)
  AUTHORS   Martinez-Marmol,R., Muhaisen,A., Cotrufo,T., Rosello-Busquets,C.,
            Ros,O., Hernaiz-Llorens,M., Perez-Branguli,F., Andres,R.M.,
            Parcerisas,A., Pascual,M., Ulloa,F. and Soriano,E.
  TITLE     Syntaxin-1 is necessary for UNC5A-C/Netrin-1-dependent
            macropinocytosis and chemorepulsion
  JOURNAL   Front Mol Neurosci 16, 1253954 (2023)
   PUBMED   37829513
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 9320)
  AUTHORS   Przyborski,S.A., Knowles,B.B. and Ackerman,S.L.
  TITLE     Embryonic phenotype of Unc5h3 mutant mice suggests chemorepulsion
            during the formation of the rostral cerebellar boundary
  JOURNAL   Development 125 (1), 41-50 (1998)
   PUBMED   9389662
REFERENCE   7  (bases 1 to 9320)
  AUTHORS   Kent,J., Lee,M., Schedl,A., Boyle,S., Fantes,J., Powell,M.,
            Rushmere,N., Abbott,C., van Heyningen,V. and Bickmore,W.A.
  TITLE     The reticulocalbin gene maps to the WAGR region in human and to the
            Small eye Harwell deletion in mouse
  JOURNAL   Genomics 42 (2), 260-267 (1997)
   PUBMED   9192846
REFERENCE   8  (bases 1 to 9320)
  AUTHORS   Ackerman,S.L., Kozak,L.P., Przyborski,S.A., Rund,L.A., Boyer,B.B.
            and Knowles,B.B.
  TITLE     The mouse rostral cerebellar malformation gene encodes an
            UNC-5-like protein
  JOURNAL   Nature 386 (6627), 838-842 (1997)
   PUBMED   9126743
REFERENCE   9  (bases 1 to 9320)
  AUTHORS   Lane,P.W., Bronson,R.T. and Spencer,C.A.
  TITLE     Rostral cerebellar malformation, (rcm): a new recessive mutation on
            chromosome 3 of the mouse
  JOURNAL   J Hered 83 (4), 315-318 (1992)
   PUBMED   1401878
REFERENCE   10 (bases 1 to 9320)
  AUTHORS   Boyer,B.B. and Kozak,L.P.
  TITLE     The mitochondrial uncoupling protein gene in brown fat: correlation
            between DNase I hypersensitivity and expression in transgenic mice
  JOURNAL   Mol Cell Biol 11 (8), 4147-4156 (1991)
   PUBMED   1712903
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC170085.2, AC158552.5 and AC157492.17.
            
            On Dec 21, 2022 this sequence version replaced NM_001293561.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK141181.1, AK142411.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849385, SAMN00849387
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-239               AC170085.2         21542-21780         c
            240-461             AC158552.5         156449-156670       c
            462-605             AC158552.5         119870-120013       c
            606-709             AC158552.5         100716-100819       c
            710-890             AC158552.5         76763-76943         c
            891-1058            AC158552.5         66046-66213         c
            1059-1223           AC158552.5         63475-63639         c
            1224-1280           AC158552.5         47744-47800         c
            1281-1472           AC158552.5         45595-45786         c
            1473-1817           AC158552.5         44584-44928         c
            1818-1905           AC158552.5         42778-42865         c
            1906-2074           AC158552.5         33210-33378         c
            2075-2308           AC158552.5         30704-30937         c
            2309-2458           AC158552.5         17722-17871         c
            2459-2623           AC158552.5         16462-16626         c
            2624-2802           AC158552.5         6978-7156           c
            2803-9052           AC158552.5         1-6250              c
            9053-9320           AC157492.17        5666-5933
FEATURES             Location/Qualifiers
     source          1..9320
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 65.57 cM"
     gene            1..9320
                     /gene="Unc5c"
                     /gene_synonym="B130051O18Rik; rcm; Unc5h3"
                     /note="unc-5 netrin receptor C"
                     /db_xref="GeneID:22253"
                     /db_xref="MGI:MGI:1095412"
     exon            1..239
                     /gene="Unc5c"
                     /gene_synonym="B130051O18Rik; rcm; Unc5h3"
                     /inference="alignment:Splign:2.1.0"
     CDS             116..2968
                     /gene="Unc5c"
                     /gene_synonym="B130051O18Rik; rcm; Unc5h3"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; netrin receptor UNC5C; rostral cerebellar
                     malformation protein; unc5 homolog 3; UNC-5 homolog 3;
                     unc-5 homolog C"
                     /codon_start=1
                     /product="netrin receptor UNC5C isoform 1 precursor"
                     /protein_id="NP_001280490.1"
                     /db_xref="CCDS:CCDS80034.1"
                     /db_xref="GeneID:22253"
                     /db_xref="MGI:MGI:1095412"
                     /translation="MRKGLRATAARCGLGLGYLLQMLVLPALALLSASGTGSAAQDDE
                     FFHELPETFPSDPPEPLPHFLIEPEEAYIVKNKPVNLYCKASPATQIYFKCNSEWVHQ
                     KDHVVDERVDETSGLIVREVSIEISRQQVEELFGPEDYWCQCVAWSSAGTTKSRKAYV
                     RIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEDIIDPAEDRNFYI
                     TIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWSVCNSRC
                     GRGYQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTLCPVDGRWTSWSKWSTCGTECTH
                     WRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLCMQGFIYPISTEHRPQNEYGFSSAPD
                     SDDVALYVGIVIAVTVCLAITVVVALFVYRKNHRDFESDIIDSSALNGGFQPVNIKAA
                     RQDLLAVPPDLTSAAAMYRGPVYALHDVSDKIPMTNSPILDPLPNLKIKVYNSSGAVT
                     PQDDLAEFSSKLSPQMTQSLLENEALNLKNQSLARQTDPSCTAFGTFNSLGGHLIIPN
                     SGVSLLIPAGAIPQGRVYEMYVTVHRKENMRPPMEDSQTLLTPVVSCGPPGALLTRPV
                     ILTLHHCADPSTEDWKIQLKNQAVQGQWEDVVVVGEENFTTPCYIQLDAEACHILTEN
                     LSTYALVGQSTTKAAAKRLKLAIFGPLCCSSLEYSIRVYCLDDTQDALKEVLQLERQM
                     GGQLLEEPKALHFKGSIHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHIWSGSQRNLHC
                     TFTLERLSLNTVELVCKLCVRQVEGEGQIFQLNCTVSEEPTGIDLPLLDPASTITTVT
                     GPSAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLNLDRYLNYFATKSSPTGVILDL
                     WEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAEGQY"
     exon            240..461
                     /gene="Unc5c"
                     /gene_synonym="B130051O18Rik; rcm; Unc5h3"
                     /inference="alignment:Splign:2.1.0"
     exon            462..605
                     /gene="Unc5c"
                     /gene_synonym="B130051O18Rik; rcm; Unc5h3"
                     /inference="alignment:Splign:2.1.0"
     exon            606..709
                     /gene="Unc5c"
                     /gene_synonym="B130051O18Rik; rcm; Unc5h3"
                     /inference="alignment:Splign:2.1.0"
     exon            710..890
                     /gene="Unc5c"
                     /gene_synonym="B130051O18Rik; rcm; Unc5h3"
                     /inference="alignment:Splign:2.1.0"
     exon            891..1058
                     /gene="Unc5c"
                     /gene_synonym="B130051O18Rik; rcm; Unc5h3"
                     /inference="alignment:Splign:2.1.0"
     exon            1059..1223
                     /gene="Unc5c"
                     /gene_synonym="B130051O18Rik; rcm; Unc5h3"
                     /inference="alignment:Splign:2.1.0"
     exon            1224..1280
                     /gene="Unc5c"
                     /gene_synonym="B130051O18Rik; rcm; Unc5h3"
                     /inference="alignment:Splign:2.1.0"
     exon            1281..1472
                     /gene="Unc5c"
                     /gene_synonym="B130051O18Rik; rcm; Unc5h3"
                     /inference="alignment:Splign:2.1.0"
     exon            1473..1817
                     /gene="Unc5c"
                     /gene_synonym="B130051O18Rik; rcm; Unc5h3"
                     /inference="alignment:Splign:2.1.0"
     exon            1818..1905
                     /gene="Unc5c"
                     /gene_synonym="B130051O18Rik; rcm; Unc5h3"
                     /inference="alignment:Splign:2.1.0"
     exon            1906..2074
                     /gene="Unc5c"
                     /gene_synonym="B130051O18Rik; rcm; Unc5h3"
                     /inference="alignment:Splign:2.1.0"
     exon            2075..2308
                     /gene="Unc5c"
                     /gene_synonym="B130051O18Rik; rcm; Unc5h3"
                     /inference="alignment:Splign:2.1.0"
     exon            2309..2458
                     /gene="Unc5c"
                     /gene_synonym="B130051O18Rik; rcm; Unc5h3"
                     /inference="alignment:Splign:2.1.0"
     exon            2459..2623
                     /gene="Unc5c"
                     /gene_synonym="B130051O18Rik; rcm; Unc5h3"
                     /inference="alignment:Splign:2.1.0"
     exon            2624..2802
                     /gene="Unc5c"
                     /gene_synonym="B130051O18Rik; rcm; Unc5h3"
                     /inference="alignment:Splign:2.1.0"
     exon            2803..9320
                     /gene="Unc5c"
                     /gene_synonym="B130051O18Rik; rcm; Unc5h3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      9304..9309
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Unc5c"
                     /gene_synonym="B130051O18Rik; rcm; Unc5h3"
                     /note="hexamer: ATTATA"
     polyA_site      9320
                     /gene="Unc5c"
                     /gene_synonym="B130051O18Rik; rcm; Unc5h3"
                     /note="major polyA site"
ORIGIN      
        1 gttatttctc aggactgcct ggcggtggcc ggatccagcc tcctgcctgg ctgggctttc
       61 ggctgtttgc gcgtctcctg gtggcgtttc ccttccccgt acacctctgc cgacgatgag
      121 gaaaggtctg agggcgacag cggcccgctg cggactggga ctaggatact tgctgcagat
      181 gcttgtgtta cctgccctgg ccctgctaag cgccagtggc accggctccg ccgctcaaga
      241 tgatgaattt tttcacgaac tcccagaaac ctttccatct gacccacctg agccattgcc
      301 acacttcctc attgagcccg aggaagctta cattgtgaag aacaagcctg tgaacctgta
      361 ttgtaaagcc agccctgcca cccagatcta cttcaagtgc aacagcgagt gggttcatca
      421 gaaggaccac gtagtagacg agagagtaga tgaaacctct ggtctaattg tgagagaagt
      481 gagcattgag atttcacgcc agcaggtgga ggaactgttt gggcctgaag attactggtg
      541 ccagtgtgtg gcctggagct cagcaggcac tacgaagagt cggaaggcat acgtgcgcat
      601 tgcgtatctg cggaagacat tcgagcagga acccttggga aaggaagtgt ccttggagca
      661 ggaagtctta ctccagtgtc ggccacctga agggatccca gtggctgagg tagaatggct
      721 aaagaatgaa gacataattg atcctgctga agatcggaac ttttatatta ctatcgatca
      781 caacctgatc atcaagcaag cccgactctc agatacagca aattatacct gtgttgccaa
      841 aaatattgtt gccaagagaa aaagcaccac agccactgtc atcgtgtatg ttaatggtgg
      901 ctggtccacc tggacagagt ggtctgtgtg taacagccgc tgtgggcgag gatatcagaa
      961 acgcacaaga acctgcacca acccagcccc actcaatggt ggggccttct gtgaggggca
     1021 gagtgtgcag aaaatagcat gcactacgtt atgtccagtg gatggtaggt ggacttcatg
     1081 gagcaaatgg tcaacctgtg ggactgaatg cacccactgg cgcaggaggg agtgtacagc
     1141 accagccccc aagaacgggg gtaaggactg tgatggcctg gtcctccaat ccaagaactg
     1201 cactgatggg ctgtgcatgc agggattcat ttaccccatt tcaactgagc acagacccca
     1261 gaatgaatat ggattttctt ctgctcctga ctcagatgat gtggctctct acgtggggat
     1321 tgtgatcgct gtaacagtct gtctggcgat cactgttgtg gtggccctgt ttgtgtatcg
     1381 gaagaaccac cgtgactttg agtctgacat cattgactcc tcagcactca atggcggctt
     1441 tcagcctgtg aacatcaagg ctgccagaca agatctcctg gctgtccccc ctgacctcac
     1501 ctcagctgca gccatgtaca ggggacctgt ctatgctctg catgatgtct cagacaaaat
     1561 cccaatgacc aactctccaa ttctggaccc actacccaac ttgaaaatca aagtgtacaa
     1621 cagctcaggt gctgtcactc ctcaggatga ccttgccgag ttctcatcca aactgtcacc
     1681 ccagatgacc cagtccttgc tagagaatga ggcccttaac ctgaagaacc agagcctcgc
     1741 aagacagact gacccatcct gcacagcatt tggtaccttc aactctcttg ggggtcacct
     1801 catcattcct aattcaggag taagcttgct gattcccgct ggggccattc ctcaggggag
     1861 agtctatgaa atgtatgtga ctgtacacag gaaagaaaat atgaggcccc ccatggaaga
     1921 ctctcagacc ctacttaccc ctgtggtgag ctgtgggcct cctggagctc tgctgacccg
     1981 ccctgtcatc ctcactctgc atcactgtgc agaccccagc accgaggact ggaagatcca
     2041 gctcaaaaac caggcagtgc agggacaatg ggaggatgtt gtggtggttg gggaggagaa
     2101 cttcacaacc ccctgttaca ttcagctgga tgcagaggct tgccatatcc tcacagagaa
     2161 cctcagtacc tatgccctgg ttgggcagtc caccaccaaa gcagctgcca agcgtcttaa
     2221 actggccatc tttgggcccc tctgctgctc ttccctggag tacagcatta gagtctactg
     2281 cctggatgac acacaggatg ccctgaagga agttctacaa ctggagaggc aaatgggagg
     2341 acagctccta gaagaaccca aggctcttca ttttaaaggc agcatccaca acctgcgcct
     2401 gtctattcat gacatcgccc attccctctg gaagagcaaa ttgctggcta agtatcagga
     2461 aattccattt taccacatct ggagtggctc tcaaagaaac ctccactgca ccttcactct
     2521 ggaaagactc agcctaaaca cagtggaact ggtttgcaaa ctctgtgtgc ggcaggttga
     2581 aggagaaggg cagatcttcc agctcaactg tactgtgtca gaggaaccta ctggcatcga
     2641 cttacctctc ctggaccctg ctagtaccat caccactgtc accggaccaa gtgctttcag
     2701 cattcctctc cctatccggc agaagctatg cagcagcctg gatgcccctc aaacaagagg
     2761 ccatgactgg aggatgctgg cccataaact caacctggac aggtacttga attactttgc
     2821 caccaaatcg agcccaactg gcgtaatcct ggatctttgg gaagcacaga acttcccaga
     2881 tggaaacctg agcatgctgg cagccgtcct ggaagaaatg ggaagacatg agacagtggt
     2941 gtccttggca gcagaaggac agtattgacc acactggaac taaagctgaa ggacacaatt
     3001 acacagggag tctgtgttca ggggaaccac atctgaggag gaaatccaga taggaccaag
     3061 gcgctctaca ggcaagatgg caacaggaaa cttgggggac agatataacc accaaggtac
     3121 acgcccactt cattcggaca gcaccaccgc gggagttaag aaaaattgtg taaatttgta
     3181 ccttgaattt aagaatcaat ctaattttct cttcgttggg ctgtatgctg tatggtacag
     3241 gatcttacag tttcctagga aacgcttttt attgctatcc agatgtatgg ataaactttc
     3301 ttaacaaacc cagtttctac aaatgttgtt tacatcaaat tggacaggga tgcagacact
     3361 gtccatggct cgttctattt ttgttcagat catttgaagt tgaagctgtg gacagtttat
     3421 tgtgtctatt tcagattagt aatttacaga gaaatcacag acttttgcta aaaatcatgt
     3481 acatcaagtg tctcagataa tcttcccatc agtgttctgt ttctgaaact tgttggacca
     3541 gtattggcat tggtatcagg gaagtggaga atctaaatgt aaaggagaaa ttgagaaaat
     3601 tccttatatc ctggggtaac cccgttggta tcctttggga acagagctct agcattacag
     3661 gggaggtagc tattcatgtt cctccacaca aacatttctg taccacatgt gtgtttgtaa
     3721 taagcaattt caagtgtttt ttaaaaaata ttatcattat tattgatgat tattacaaat
     3781 attctagtaa aaagaatttc cttttgtttt agttagcaat actgttagtg tttggtgttg
     3841 actagacctg cctccctttc ttgcctaaag aggtgggcat ggtcaccagt ttagttcaat
     3901 agcttttgct tccttgacct ttggtctacc attctgtggt ggaaaagaca gaaatgctca
     3961 atggctatgt ctgctctttc agcttgctcg gtcagagtct ttctgttctt gctcttatca
     4021 tgaggagagt tctctatgta aagttcattt actcttgtgg ctatctggga ggcagtatgg
     4081 ttgtgggaac agtgtctgaa ctaggaatca ggaaaccagt tatccttgtg gagttggtcc
     4141 ctgtatggct gtgtgacttt ggggaaaaca ttgaaactca ctggcgctca ttgcccttct
     4201 ttgtaaactt tgtggtgaga ccagatcatc tcaaggttcc agaatgctga tctcccattc
     4261 aaatgtcatc atccttttct atcttgcagg caggattgat ttgaacaggg attacttcaa
     4321 cacacatttg tttgtcttta tctttgtgtc attattgcat gatgttgttc gcttagagat
     4381 ggcatccttt tcttaccatt gtcttgacct ctgctggggc cctaatgtcc agccttccaa
     4441 ctaactgtaa attctacttt actcatttat tgatctccag atctcaagac catttctaca
     4501 aaaagcccat gcagctgaat gaattggtaa catttttctt tctttattac tctttgcttt
     4561 agtaatattc agttgtattt atgtagatta gtgctatagg accatcctat aaaacgttag
     4621 ttgtgcatac tccttgggac catcctgggt tttgtttgtt tgttagtttg tttttatttt
     4681 ttgatatagg aactccattc agcagatagt gaatgaaaac ttagcagccc cactgacata
     4741 gttaaataga aagcacctat gcccttaagt cagaaacttc aaaatatggc tgtggtgtac
     4801 tttggggcta gaagtattca ggttgctgaa tggattccat tgggaatcat tttgcctaat
     4861 accctctgat tctgttactt cctgatacac gctaactctt ctatcctagt cattaaagaa
     4921 ctgtgggtac agttgtggag cctcttcctt catgctgttt gtcttctctt tcagagatgt
     4981 attctacagt ctctttctct aaccatattc atatataaaa atcctggtcc cactgactgt
     5041 ggaagggaaa ttctatactc ctaacgaagt ttgttggctg atatctgtaa gcatgagttt
     5101 gttcgaactt ttaagagttt gattgatgtt cttaaaaagt aagaggaaga aagactttgc
     5161 tgcctcttga aacaagtgtg aaggttcctc tacacttctt ggattttgga accatcaaag
     5221 aaatccaaac tgagaggtct ggactggatg ttctgtgtaa cttcaatgct ttgtgctaag
     5281 tcaagaggaa caaatatgtt gctattctgg ttaatttatc ctaaaaactg ttaagtcacc
     5341 aacacagaaa tactgaatat aaccaaagca acattattga atattttgag agtcctcgtg
     5401 ttcaagcatc tagagatact tgcttttgta ttcagactct cacaacagga aaaggaaaaa
     5461 tgactgatct cttatgaagg aatcatatgt cataaaacca ctttctatca tgtgaatgac
     5521 agtttccaaa ctagaacata ccatacatca aataattttc actaagcagt ctgctctttc
     5581 tccttgggaa gaaaatgata gttgttagat tgctgctttc caacacacac gtttcacctg
     5641 ccacagttca tcttagaggg agcttcatca tcacccctgt ggcatgtctg acttctacag
     5701 agcttctcag gaatgccttg cttgctgtgg gtgggtagaa aaacaaatta tttgtgcctg
     5761 gtgccatcta gtggcctgcc acatagttac tcaatgtcat atacagctta caaaaaatta
     5821 acaaagagag ttaagtacct gtggagttcg acatttgtga caaatagaca tggtgaaatt
     5881 tacctacatg tgtaattctc ttattctcgt attcttcagt taaattatcc attttacaac
     5941 tttctgggta tagcacgtca tcaacttact catacacatc ttaagttact ttcttgtgat
     6001 agacatgtat ggaatctgta tttttaaaag tctctgaaaa ttgtcattgg gctttgcata
     6061 tttgaaatct tttaactccc aaacactgac ttttagaaat ataaactgta ttcacaaaga
     6121 agaaagattc cctgcccaac agctccacac acatggcatc accttgggca tatatattct
     6181 tgctaggtat cccagaacat catcaaatcc atgaccctat ttccacagcc tctcaagtgg
     6241 tgagagttta actatgtacc actatacctg ttcaaacctg ctctacattt gtaaatgaga
     6301 atcctgtctc tatggacatg gaagttgtgg ctgttaatca agacgaatga tcttcagatg
     6361 aagtagacct gagattagga atctaaaact tcatgttctc ttcttattga cattaattca
     6421 aattggcttg agtctaagca tgtgtcaaga aagtcacagc caaacatttt caaagcagac
     6481 acattgtctc tgctacacaa agaattccat cctgacctga gcaaattaat ctcttctggg
     6541 aaaggataat ttggggaata agaggtccaa gatcaaagta tatcattagc tattttcata
     6601 tattctatga ttctaaagat tttaattatt ccactatcaa agagtagaga catcctttag
     6661 gggaaagttg caatgactat atttaggatc ctctaggaaa taggtattaa aactaggttt
     6721 taaggacatt tctcctaaaa atgattgaaa gggaaacact cagagggtag gatttagaca
     6781 gttcacatct ggaagagagt agatggttgc ctacatctct gtgtgtctct gatgaggacc
     6841 tggcacctat gatcctgggt cattcacaca cacctacata gccataggac aaagagagct
     6901 tatagggaga atgttctatc ccacaatcca tacacatccc tacagtctgc gctctggagc
     6961 taatcaatgt agaaggatgt tagataatat gagagaaaaa gtaagaaaga tttacttatt
     7021 ccccggtctt caagatgaac acgaatttga gctgagtaat tgctctggaa aagtaatcta
     7081 ttcagagata tgtgctggtg taagtccaag gccagtggtg gcaaaggagg attacagaaa
     7141 cacagtgtgg gtggacttag gctcgagaca cctttactga gcagctttgt aaaccaggac
     7201 atcattgttc aaatcaatca tttgtaaaga tgataatggc caatgagcat cttattttat
     7261 agatccaaaa gaaaaatatt tttattatta ttctcaagat aataaaactg gttttttgcc
     7321 ttctgagtgc ctcgtgggac caactatctt actcctttag ttttgtattg tttttgtatt
     7381 tttaaagcat actgagctga cattgactga aaacctttta actctctgtc tatacaacaa
     7441 aatcctgttt ctctacccca agatatccga ttgtgtcacc tctgcttaca ctgaccactt
     7501 tgacagtcac ccgataactt tttgatggga ttgggactat gaggaataca cttattataa
     7561 ccaatactaa tttatggtca tataggctaa ataagccata tgaagtcata cctgtttcta
     7621 aaaagctgac acttaagctc attggtttaa tgagtagaga tggcctgcat gtaccagggt
     7681 ggaatatctc ttcaaactaa caatgcagtt gtgaatcctt tagttctttt ggtcaaatgg
     7741 ttgccccctt ttctgaaaac ttactgcaat agtcttcaga aagtccagtg ggcttgccta
     7801 cttcctttct tgatctgtgg tgggatatta acaggcttat tcaaccaaag gtgttttcag
     7861 aggcctattt aattgtggct ggggtatcct caggacaaat agatgcactc cataaatata
     7921 ctagcaggca aagccaaaga gatgtaagtg gcgacctgca agtcttcagt atactaaact
     7981 ttatatgaag gtatctatcc caagagtacc aaaatgctac attggaaacc cttgccatat
     8041 atcaggacag tcatggccaa acccactagt tactaagcag aaaaccagag agtgtcctga
     8101 aatacaatca gctgtccacc agccatgtta tttgctatgg tacaccagct ttttatatat
     8161 catttgggaa cctgtgctat ggcagaatta taaattgcag gtaaaattac tgtaagaccc
     8221 attttaaata agcctaaacc ccataccatc tttatatgcc aaaggcctaa tgccatggag
     8281 cctgatgacc cgtggccatg gtgactgtca actgtgggct agttgtcttg atgggcagcc
     8341 taagggatga gctctctgcc tttgatcttc actcagtgat gatgtggcaa catcaaagca
     8401 tcctgatgag ctctgtgctg tattaaaccc attttaagat agcattccaa acaaatccac
     8461 agctagtaga aaatgccttt gcccatttct gtgtttctaa agacattaat ggcacctata
     8521 actgcataca tatgtattca gatatatttt tctccagatt attggaaaga aagaggagcc
     8581 agttgaagac atgactcgca ttctttcttt cacttgttcc tagtcccgac tatgggtatt
     8641 gatgccctca cccttcagac aatgtattta gccaagttgc agggaatatc attattgtat
     8701 gtatactgtg tgtatgtgtg tgtgtgtgta tgtgtgtgta agatgtcaca gtgttgtgtt
     8761 tattaagctt aatgttgagc tgtaaggaac cagtaatctt cctccgtgct ctaaagaaga
     8821 aaacccatat tcatgagaga acaatcccag ctttctgctt taaaaaaaaa aaaaaaaaaa
     8881 aaaaaggaag aagcagctgg gtcaccctcc tgctgtcttc tttggaccag ttcaacttca
     8941 gaagtatcag gttgaaattt tatgctttgt cagtttttct ttttttagca aaacaacatg
     9001 accttggctt ctcagatatg gagcacttct tccttccttt gttatggaat tctgtcttgc
     9061 tgtatcttct atgcaactcc tttcctaatg acccccagtg gctgcggagt gctctccagc
     9121 attctgctca tcctcatcgc cttgctgtgt ggttgaggtg taccggcttt gggtgtgcct
     9181 cttttctctc tctggttgcc tcacccaatt tacctgccgt ccccttggtt tgtaaactgc
     9241 ctgcatttac tcttgtcagc caacatgtac aaatgtaaga aagaattttt aaacaggtaa
     9301 taaattatat ttataagcaa
//
