LOCUS       NM_177589               4093 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus unc-51-like kinase 4 (Ulk4), mRNA.
ACCESSION   NM_177589 XM_001479566 XM_001481114
VERSION     NM_177589.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4093)
  AUTHORS   McCoy,C.J., Paupelin-Vaucelle,H., Gorilak,P., Beneke,T., Varga,V.
            and Gluenz,E.
  TITLE     ULK4 and Fused/STK36 interact to mediate assembly of a motile
            flagellum
  JOURNAL   Mol Biol Cell 34 (7), ar66 (2023)
   PUBMED   36989043
  REMARK    GeneRIF: ULK4 and Fused/STK36 interact to mediate assembly of a
            motile flagellum.
REFERENCE   2  (bases 1 to 4093)
  AUTHORS   Hu,L., Zhou,B.Y., Yang,C.P., Lu,D.Y., Tao,Y.C., Chen,L., Zhang,L.,
            Su,J.H., Huang,Y., Song,N.N., Chen,J.Y., Zhao,L., Chen,Y., He,C.H.,
            Wang,Y.B., Lang,B. and Ding,Y.Q.
  TITLE     Deletion of Schizophrenia Susceptibility Gene Ulk4 Leads to
            Abnormal Cognitive Behaviors via Akt-GSK-3 Signaling Pathway in
            Mice
  JOURNAL   Schizophr Bull 48 (4), 804-813 (2022)
   PUBMED   35522199
  REMARK    GeneRIF: Deletion of Schizophrenia Susceptibility Gene Ulk4 Leads
            to Abnormal Cognitive Behaviors via Akt-GSK-3 Signaling Pathway in
            Mice.
REFERENCE   3  (bases 1 to 4093)
  AUTHORS   Mecklenburg,N., Kowalczyk,I., Witte,F., Gorne,J., Laier,A.,
            Mamo,T.M., Gonschior,H., Lehmann,M., Richter,M., Sporbert,A.,
            Purfurst,B., Hubner,N. and Hammes,A.
  TITLE     Identification of disease-relevant modulators of the SHH pathway in
            the developing brain
  JOURNAL   Development 148 (17) (2021)
   PUBMED   34463328
REFERENCE   4  (bases 1 to 4093)
  AUTHORS   Hu,L., Chen,Y., Yang,C.P., Huang,Y., Song,N.N., Chen,J.Y.,
            Sun,Y.L., Ding,Y.Q. and Lang,B.
  TITLE     Ulk4, a Newly Discovered Susceptibility Gene for Schizophrenia,
            Regulates Corticogenesis in Mice
  JOURNAL   Front Cell Dev Biol 9, 645368 (2021)
   PUBMED   34235142
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4093)
  AUTHORS   Liu,M., Fitzgibbon,M., Wang,Y., Reilly,J., Qian,X., O'Brien,T.,
            Clapcote,S., Shen,S. and Roche,M.
  TITLE     Ulk4 regulates GABAergic signaling and anxiety-related behavior
  JOURNAL   Transl Psychiatry 8 (1), 43 (2018)
   PUBMED   29391390
  REMARK    GeneRIF: Ulk4 +/tm1a mice exhibit anxiety-related phenotype.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4093)
  AUTHORS   Liu,M., Xu,P., Guan,Z., Qian,X., Dockery,P., Fitzgerald,U.,
            O'Brien,T. and Shen,S.
  TITLE     Ulk4 deficiency leads to hypomyelination in mice
  JOURNAL   Glia 66 (1), 175-190 (2018)
   PUBMED   29034508
  REMARK    GeneRIF: This is the first evidence demonstrating that ULK4 is a
            crucial regulator of myelination, and ULK4 may therefore become a
            novel therapeutic target for hypomyelination diseases.
REFERENCE   7  (bases 1 to 4093)
  AUTHORS   Liu,M., Guan,Z., Shen,Q., Flinter,F., Dominguez,L., Ahn,J.W.,
            Collier,D.A., O'Brien,T. and Shen,S.
  TITLE     Ulk4 Regulates Neural Stem Cell Pool
  JOURNAL   Stem Cells 34 (9), 2318-2331 (2016)
   PUBMED   27300315
  REMARK    GeneRIF: Targeted disruption of the Ulk4 perturbed mid-neurogenesis
            and significantly reduced cerebral cortex in postnatal mice.
REFERENCE   8  (bases 1 to 4093)
  AUTHORS   Liu,M., Guan,Z., Shen,Q., Lalor,P., Fitzgerald,U., O'Brien,T.,
            Dockery,P. and Shen,S.
  TITLE     Ulk4 Is Essential for Ciliogenesis and CSF Flow
  JOURNAL   J Neurosci 36 (29), 7589-7600 (2016)
   PUBMED   27445138
  REMARK    GeneRIF: This study showed that Ulk4 Is essential for Ciliogenesis
            and CSF Flow in mice
REFERENCE   9  (bases 1 to 4093)
  AUTHORS   Lang,B., Pu,J., Hunter,I., Liu,M., Martin-Granados,C., Reilly,T.J.,
            Gao,G.D., Guan,Z.L., Li,W.D., Shi,Y.Y., He,G., He,L.,
            Stefansson,H., St Clair,D., Blackwood,D.H., McCaig,C.D. and Shen,S.
  TITLE     Recurrent deletions of ULK4 in schizophrenia: a gene crucial for
            neuritogenesis and neuronal motility
  JOURNAL   J Cell Sci 127 (Pt 3), 630-640 (2014)
   PUBMED   24284070
REFERENCE   10 (bases 1 to 4093)
  AUTHORS   Vogel,P., Read,R.W., Hansen,G.M., Payne,B.J., Small,D., Sands,A.T.
            and Zambrowicz,B.P.
  TITLE     Congenital hydrocephalus in genetically engineered mice
  JOURNAL   Vet Pathol 49 (1), 166-181 (2012)
   PUBMED   21746835
  REMARK    GeneRIF: Congenital hydrocephalus with suppurative rhinosinusitis
            and otitis media in Ulk4 null mice indicative of primary ciliary
            dyskinesis
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK132731.1, BC065094.1, BM938704.1 and AW456669.1.
            
            On or before Apr 19, 2009 this sequence version replaced
            XM_001479566.1, XM_001481114.1, NM_177589.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMN00849374, SAMN00849375
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2546              AK132731.1         2-2547
            2547-2554           BC065094.1         2845-2852
            2555-3505           AK132731.1         2556-3506
            3506-4043           BM938704.1         70-607
            4044-4093           AW456669.1         1-50                c
FEATURES             Location/Qualifiers
     source          1..4093
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 72.19 cM"
     gene            1..4093
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /note="unc-51-like kinase 4"
                     /db_xref="GeneID:209012"
                     /db_xref="MGI:MGI:1921622"
     exon            1..113
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            114..297
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     CDS             160..3987
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /EC_number="2.7.11.1"
                     /codon_start=1
                     /product="serine/threonine-protein kinase ULK4"
                     /protein_id="NP_808257.2"
                     /db_xref="CCDS:CCDS52967.1"
                     /db_xref="GeneID:209012"
                     /db_xref="MGI:MGI:1921622"
                     /translation="MENFVLYEEIGRGSRTVVYKGRRKGTINFVAILCTEKCKRPEIT
                     NWVRLTHEIKHKNIVTFHEWYETSNHLWLVVELCTGGSLETVIAQDENLPEDVVREFG
                     VDLVTGLHHLHRLGILFCDLSPGKILLEGPGTLKFSNFCLAKVAGESLEEFFALVAAE
                     EGGGDSGENALKKSMKTRVRGSLIYAAPEIVKGTEFSVTSDLWSLGCLLYEMFSGKPP
                     FFSETVSELVEKILYEDPLPPIPKDSSFPKASSDFLNLLDGLLQKDPQKRFSWEGVLQ
                     HPFWKDALRGEDSGWASEDSPFSRNVMECSGPHDSRELLQSPKNGQAKGQKAAHRLSQ
                     SFRLENPTELRPKSIMGGQLNESIFLLSSRPTPRTSAMVELNPGEGEDPSSPQKTSPL
                     SKMTSGHLSQGALESQMRELIYTDSDLVITPIIDNPKIMKQPAIKFDPKILHLPAYSV
                     EKLLVLKDQDWNDFLQQVCSQIDSSEKSTGALRAKLNLLCYLCVVATHKEVATRLLHS
                     PLFQLLIQHLRIAPNWDIRSKVARVVGMLALHTTELQENVPVIEAITLLTELIRENFR
                     SGKLKQCLLPTLGQLLYLVATQEEKNQHSRDCWAVPLAAYTVLMRCLREGEERVVNHM
                     AAKIIENVCTTFSAQAQGFTTGEIGPVLWHLFRHSTVDALRITAISALCRITRQSPTA
                     FQNVIEKVGLNAVISSLASAICKVQQYMLTLFTAMLSCGIHLQRLIQEKDFVSTVIRL
                     LDSPSTPIRAKAFLVLLYILIHNRDMLLLSCQARLVMYIERDSRKTSPGKEQQSGNEY
                     LARCLDLLIQHMVQEPPRILGDILNALANVSGRKHPSTVQGKQLKMCLPMMPVVLHLV
                     MSQVFRPQVVTEEFLFSYGTILSHIKSIDLGETNIDGAIGIVASEEFIKVTLSAFEAV
                     IQYPVLLADYRSTVMDYILPPLVSLVQSQNVEWRLFSLRLLSETTTLLVSQEPEDGDE
                     EASCDSDSSLLALIRDELLPQYEHILMEPDPVPAYALKLLVAMTEHNPAFTRLVEESK
                     LVPLIFEVILEHQESILGNTMQSVIALLNNLVAYKDSNMQLLYEQGLVGHVCNMFTET
                     ATLCLDRDNKTNTEPASTLLASLLDILLGMLTYTSRIVRQALQVQKSGSRGDTQAAED
                     LLLLSKPLTDLISLLIPLLPSEDPEISEVSSKCLSILVQLYGGENPESLSPENMVTFA
                     NLLMTKEDPKDQKLLLRILKRMVTSNERLLESLKNTGSLLQALERLAPAHSSPVDTIV
                     ASLALELLQAVGH"
     exon            298..397
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            398..537
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            538..700
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            701..802
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            803..886
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            887..962
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            963..1055
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            1056..1174
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            1175..1244
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            1245..1341
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            1342..1446
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            1447..1507
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            1508..1689
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            1690..1736
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            1737..1815
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            1816..1923
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            1924..2007
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            2008..2169
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            2170..2352
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            2353..2480
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            2481..2614
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            2615..2736
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            2737..2793
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            2794..2845
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            2846..2940
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            2941..2992
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            2993..3137
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            3138..3230
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            3231..3279
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            3280..3385
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            3386..3552
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            3553..3651
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            3652..3837
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            3838..3923
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     exon            3924..4078
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4058..4063
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /note="hexamer: AATAAA"
     polyA_site      4078
                     /gene="Ulk4"
                     /gene_synonym="4932415A06Rik; A730098P15"
                     /note="major polyA site"
ORIGIN      
        1 gcgtccaggg gagttggcca ggtcttcggg tgcctcggtt tcctctgtcc aagctgtggc
       61 ctcgccgtgg caaggcagag cgcgtgcaac tcgggtcccc caccatcgtg caggagctag
      121 acatgctgtt ttaccgtata tgagcagtcg atcccagata tggaaaactt cgtcttgtat
      181 gaggagattg gcagaggaag caggactgtc gtatataagg ggcgccggaa aggaaccatc
      241 aactttgtag ccatcctttg tactgagaag tgcaaacggc ctgaaataac caactgggtc
      301 cgcctcaccc atgaaataaa acacaagaac attgtaactt ttcacgagtg gtacgagacc
      361 agcaatcatc tctggttggt ggtggagctt tgcacaggtg gttctctaga aaccgtgatt
      421 gctcaggacg aaaacctccc agaagatgtc gtgagagagt ttggggtgga cctggtcaca
      481 gggctgcacc atctccacag gctgggcatc ctcttttgtg acctttctcc tgggaagatt
      541 ctcttggaag ggcctggaac actgaagttc agcaatttct gcctggccaa ggtggcaggg
      601 gagagtctgg aggagttctt tgctttggtg gcagcagaag aaggaggtgg tgacagtgga
      661 gagaacgcac tgaagaaaag catgaagacc cgagtcagag gctctctgat ctatgcggct
      721 ccggaaatcg tgaaggggac tgaattctcc gttaccagtg acctctggtc tttgggctgt
      781 ctactttatg aaatgttttc agggaaaccc ccattcttct cagaaacggt gtcagaactc
      841 gttgagaaga ttctgtatga agacccattg ccaccaatcc caaaagactc ttcattcccc
      901 aaagcatcct cagatttcct taacttgctg gacggattgc tgcagaagga tcctcagaaa
      961 agattctcct gggagggagt tctgcagcac ccattctgga aagacgccct gcggggagaa
     1021 gactcaggct gggcctccga ggactccccc ttcagcagaa acgtcatgga gtgttctgga
     1081 ccgcatgatt ccagagagct tttgcagagc cctaagaatg gacaagccaa agggcagaag
     1141 gcagctcatc ggctcagcca gtctttcagg ctagaaaacc caactgagct gaggcccaag
     1201 agcatcatgg gaggccagct gaatgaatcc atatttctcc tcagttcacg gcccactcca
     1261 aggactagtg ccatggtgga attaaatcct ggtgagggtg aggaccccag ctcacctcag
     1321 aagacttctc ccttatccaa gatgacaagc gggcacctga gccagggggc cctggagtcc
     1381 cagatgagag agctgatcta cacggactcg gatcttgtga tcaccccaat tatagacaat
     1441 ccgaagataa tgaaacaacc tgcaatcaag tttgatccaa aaatcttgca cctaccagca
     1501 tattctgtgg agaagttgct ggtcctcaag gaccaagact ggaatgactt cctgcagcag
     1561 gtgtgctccc agatcgactc cagcgagaag agcacagggg cgctgcgggc caagctgaac
     1621 ctcctgtgct acctgtgtgt ggtggccacg cacaaggagg tggccaccag gctgcttcac
     1681 tccccgctgt tccagttgct aatccagcac ctgcggatag ctcctaactg ggatatacgg
     1741 tccaaggttg ctcgggtggt cggcatgctg gccttgcaca caaccgaact tcaggaaaat
     1801 gtgcctgtta tcgaggcgat cacactctta actgaattaa tccgggaaaa tttcaggagt
     1861 ggcaaactga agcagtgcct cctgcccacc cttggacagc ttctctacct tgtagccacc
     1921 caggaagaaa aaaatcagca ctccagggat tgctgggccg tccccctggc tgcatacact
     1981 gtgcttatga ggtgcctccg ggaaggggag gaacgggttg tcaatcacat ggctgcgaag
     2041 attatcgaga atgtttgcac gacgttttct gcccaggcgc agggcttcac aaccggggag
     2101 attgggcctg tcctgtggca cctctttaga cactccaccg tggacgccct gcggataacc
     2161 gcgatatcgg ccctgtgcag gatcacacgg cagtctccca ccgccttcca gaatgtcatc
     2221 gagaaggtgg gtctcaatgc agtcatcagc tccctggcct ctgccatctg caaagtgcag
     2281 cagtacatgc tgaccctgtt cacagccatg ctgtcctgtg ggattcatct ccagcggctg
     2341 atccaagaga aggacttcgt ctctacagtc atccgcttac ttgatagtcc gtccactccc
     2401 atcagagcca aagccttcct ggtgctgctg tacatcttga ttcataaccg ggacatgctg
     2461 ctgctgagct gccaagccag gctggtgatg tacatcgaga gagacagcag aaagacctcc
     2521 ccaggcaagg agcagcagag tgggaatgag tacctggcca ggtgcctgga cctcctcatc
     2581 cagcacatgg tacaggagcc acctcggatc ctaggcgaca ttctcaacgc cctggcaaac
     2641 gtgtccggcc ggaagcaccc atccacggtc caggggaagc agctgaagat gtgtctcccc
     2701 atgatgcctg tggtgcttca cctggtgatg tcacaggtat ttcgacctca agttgtgaca
     2761 gaagagtttc tcttcagcta cggaactatt cttagtcaca ttaagtcaat tgacttgggg
     2821 gaaacgaaca tagacggagc cataggcatc gtggcatctg aggagtttat caaggtcacc
     2881 ctgtcggcat tcgaagcagt gatccagtac ccggttctgc tggccgacta ccgctcgacg
     2941 gtcatggatt atattttgcc gcccttggtc tccttggttc aaagccagaa tgtggaatgg
     3001 agactcttca gcttgcggtt gctctcagag accacaaccc tgctggtgag ccaggagccg
     3061 gaggacggtg atgaagaggc cagttgcgat tctgacagca gtcttctggc gctcatcaga
     3121 gatgagctgc taccccagta tgagcacatc ctcatggagc ctgaccccgt tcctgcctat
     3181 gcgctgaagc tgctcgtcgc catgacggaa cacaaccccg ctttcaccag gcttgtggaa
     3241 gaaagcaaac tggtcccgct catttttgaa gtaattttgg agcatcagga gagcattctg
     3301 ggtaatacca tgcagagtgt gattgcgttg ctcaacaatc tggttgccta caaagactca
     3361 aacatgcagc tgctttatga acaaggactc gttggtcatg tctgtaacat gttcacagaa
     3421 actgccactc tgtgcttgga cagggacaat aaaaccaaca cggagccggc gtccacactg
     3481 ctggcctccc tgctcgacat cctactgggc atgctgacct acacttctcg aatcgtccgg
     3541 caggctttgc aggtccagaa gtcaggctca agaggggaca cacaggctgc agaggacctg
     3601 ctgcttctca gcaaaccact cacagacctc atcagcctgc ttatcccact gcttcccagc
     3661 gaggaccctg agatctccga ggtctcatcc aagtgcctgt ccatcctggt gcagctgtat
     3721 ggaggcgaga accccgagag cttgtcccca gagaacatgg tgacctttgc caacctcctg
     3781 atgaccaagg aggaccccaa ggaccagaag cttctgctga ggatcctcaa gaggatggta
     3841 acgtccaatg agaggctctt ggaaagcctc aagaacaccg gcagccttct gcaggccctg
     3901 gagcgcctgg ctccagctca cagctcaccc gtcgacacta tcgtggcttc cttggccctg
     3961 gaactcctcc aggcagttgg gcattagaca cggccatcct gtggcacagt gtggtcagat
     4021 cccacaccat cctttctcac cagtctcaag tggagctaat aaaatcaatg ggccagaaaa
     4081 aaaaaaaaaa aaa
//
