LOCUS       NM_013881               5813 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus unc-51 like kinase 2 (Ulk2), mRNA.
ACCESSION   NM_013881 XM_915847
VERSION     NM_013881.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5813)
  AUTHORS   Kremer,L.S., Bozhilova,L.V., Rubalcava-Gracia,D., Filograna,R.,
            Upadhyay,M., Koolmeister,C., Chinnery,P.F. and Larsson,N.G.
  TITLE     A role for BCL2L13 and autophagy in germline purifying selection of
            mtDNA
  JOURNAL   PLoS Genet 19 (1), e1010573 (2023)
   PUBMED   36608143
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5813)
  AUTHORS   Harris,M.P., Zhang,Q.J., Cochran,C.T., Ponce,J., Alexander,S.,
            Kronemberger,A., Fuqua,J.D., Zhang,Y., Fattal,R., Harper,T.,
            Murry,M.L., Grueter,C.E., Abel,E.D. and Lira,V.A.
  TITLE     Perinatal versus adult loss of ULK1 and ULK2 distinctly influences
            cardiac autophagy and function
  JOURNAL   Autophagy 18 (9), 2161-2177 (2022)
   PUBMED   35104184
  REMARK    GeneRIF: Perinatal versus adult loss of ULK1 and ULK2 distinctly
            influences cardiac autophagy and function.
REFERENCE   3  (bases 1 to 5813)
  AUTHORS   Drake,J.C., Wilson,R.J., Cui,D., Guan,Y., Kundu,M., Zhang,M. and
            Yan,Z.
  TITLE     Ulk1, Not Ulk2, Is Required for Exercise Training-Induced
            Improvement of Insulin Response in Skeletal Muscle
  JOURNAL   Front Physiol 12, 732308 (2021)
   PUBMED   34658916
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5813)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5813)
  AUTHORS   Fuqua,J.D., Mere,C.P., Kronemberger,A., Blomme,J., Bae,D.,
            Turner,K.D., Harris,M.P., Scudese,E., Edwards,M., Ebert,S.M., de
            Sousa,L.G.O., Bodine,S.C., Yang,L., Adams,C.M. and Lira,V.A.
  TITLE     ULK2 is essential for degradation of ubiquitinated protein
            aggregates and homeostasis in skeletal muscle
  JOURNAL   FASEB J 33 (11), 11735-11745 (2019)
   PUBMED   31361156
  REMARK    GeneRIF: that skeletal muscle ULK2 has a unique role in basal
            selective protein degradation by stimulating the recognition and
            proteolytic sequestration of insoluble ubiquitinated protein
            aggregates
REFERENCE   6  (bases 1 to 5813)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
REFERENCE   7  (bases 1 to 5813)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
REFERENCE   8  (bases 1 to 5813)
  AUTHORS   Tomoda,T., Bhatt,R.S., Kuroyanagi,H., Shirasawa,T. and Hatten,M.E.
  TITLE     A mouse serine/threonine kinase homologous to C. elegans UNC51
            functions in parallel fiber formation of cerebellar granule neurons
  JOURNAL   Neuron 24 (4), 833-846 (1999)
   PUBMED   10624947
REFERENCE   9  (bases 1 to 5813)
  AUTHORS   Yan,J., Kuroyanagi,H., Tomemori,T., Okazaki,N., Asato,K.,
            Matsuda,Y., Suzuki,Y., Ohshima,Y., Mitani,S., Masuho,Y.,
            Shirasawa,T. and Muramatsu,M.
  TITLE     Mouse ULK2, a novel member of the UNC-51-like protein kinases:
            unique features of functional domains
  JOURNAL   Oncogene 18 (43), 5850-5859 (1999)
   PUBMED   10557072
REFERENCE   10 (bases 1 to 5813)
  AUTHORS   Yan,J., Kuroyanagi,H., Kuroiwa,A., Matsuda,Y., Tokumitsu,H.,
            Tomoda,T., Shirasawa,T. and Muramatsu,M.
  TITLE     Identification of mouse ULK1, a novel protein kinase structurally
            related to C. elegans UNC-51
  JOURNAL   Biochem Biophys Res Commun 246 (1), 222-227 (1998)
   PUBMED   9600096
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK148142.1, AK146620.1, BM124275.2 and AV256860.1.
            
            On May 27, 2009 this sequence version replaced NM_013881.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK146893.1, AK148142.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3300              AK148142.1         2-3301
            3301-5207           AK146620.1         3263-5169
            5208-5761           BM124275.2         1-554               c
            5762-5813           AV256860.1         197-248
FEATURES             Location/Qualifiers
     source          1..5813
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 37.96 cM"
     gene            1..5813
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /note="unc-51 like kinase 2"
                     /db_xref="GeneID:29869"
                     /db_xref="MGI:MGI:1352758"
     exon            1..606
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     CDS             517..3630
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /EC_number="2.7.11.1"
                     /note="serine/threonine-protein kinase Unc51.2"
                     /codon_start=1
                     /product="serine/threonine-protein kinase ULK2"
                     /protein_id="NP_038909.3"
                     /db_xref="CCDS:CCDS24820.1"
                     /db_xref="GeneID:29869"
                     /db_xref="MGI:MGI:1352758"
                     /translation="MEVVGDFEYCKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKK
                     NLSKSQILLGKEIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGT
                     LSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYANRRKSNVSGIRIKIADFG
                     FARYLHSNTMAATLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANS
                     PQDLRMFYEKNRSLMPSIPRETSPYLANLLLGLLQRNQKDRMDFEAFFSHPFLEQVPV
                     KKSCPVPVPVYSGPVPGSSCSSSPSCRFASPPSLPDMQHIQEENLSSPPLGPPNYLQV
                     SKDSASNSSKNSSCDTDDFVLVPHNISSDHSYDMPMGTTARRASNEFFMCGGQCQPTV
                     SPHSETAPIPVPTQVRNYQRIEQNLISTASSGTNPHGSPRSAVVRRSNTSPMGFLRVG
                     SCSPVPGDTVQTGGRRLSTGSSRPYSPSPLVGTIPEQFSQCCCGHPQGHEARSRHSSG
                     SPVPQTQAPQSLLLGARLQSAPTLTDIYQNKQKLRKQHSDPVCPSHAGAGYSYSPQPS
                     RPGSLGTSPTKHTGSSPRNSDWFFKTPLPTIIGSPTKTTAPFKIPKTQASSNLLALVT
                     RHGPAESQSKDGNDPRECSHCLSVQGSERHRSEQQQSKAVFGRSVSTGKLSEQQVKAP
                     LGGHQGSTDSLNTERPMDVAPAGACGVMLALPAGTAASARAVLFTVGSPPHSATAPTC
                     THMVLRTRTTSVGSSSSGGSLCSASGRVCVGSPPGPGLGSSPPGAEGAPSLRYVPYGA
                     SPPSLEGLITFEAPELPEETLMEREHTDTLRHLNMMLMFTECVLDLTAVRGGNPELCT
                     SAVSLYQIQESVVVDQISQLSKDWGRVEQLVLYMKAAQLLAASLHLAKAQVKSGKLSP
                     SMAVKQVVKNLNERYKFCITMCKKLTEKLNRFFSDKQRFIDEINSVTAEKLIYNCAVE
                     MVQSAALDEMFQQTEDIVYRYHKAALLLEGLSKILQDPTDVENVHKYKCSIERRLSAL
                     CCSTATV"
     exon            607..699
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     exon            700..741
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     exon            742..774
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     exon            775..811
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     exon            812..985
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     exon            986..1059
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     exon            1060..1161
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1220
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     exon            1221..1303
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     exon            1304..1351
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     exon            1352..1440
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     exon            1441..1612
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     exon            1613..1673
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     exon            1674..1811
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     exon            1812..1957
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     exon            1958..2038
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     exon            2039..2325
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     exon            2326..2516
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     exon            2517..2620
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     exon            2621..2770
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     exon            2771..2979
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     exon            2980..3158
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     exon            3159..3277
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     exon            3278..3435
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     exon            3436..3571
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     exon            3572..5813
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4817..4822
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /note="hexamer: AATAAA"
     polyA_site      4839
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /note="major polyA site"
     regulatory      5183..5188
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /note="hexamer: AATAAA"
     polyA_site      5209
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
     regulatory      5740..5745
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /note="hexamer: AATAAA"
     polyA_site      5762
                     /gene="Ulk2"
                     /gene_synonym="A830085I22Rik; mKIAA0623; Unc51.2"
                     /note="major polyA site"
ORIGIN      
        1 ggtagtcggc gcggagcggc cggcgcgcgc gcgtgcgttg ggcgctcccg cgaagcaggc
       61 agaagccgcc accgcggctg tgcgggttcc agggcggcgg ccgctacaca gcagcgccgc
      121 gggcgcaaca agcggaggca gccgcacctg cggggatggc gcggccccgg ccctgcaccg
      181 ctgtcaggcg cgcgggtagc tccgggtacg cccagtgacg gcggcggtgc cctcggccgg
      241 gcagtgccca ggccgcttgg ctagagcccc gcggccgacg gcggcccggg ccatgagaag
      301 cgaccgggcc caggcctcgc tgaccccggc tccgcgcggc ggcccgtccc gtttccgctc
      361 cggcctctcg gcatgagtgt ccatccgggc ccggggccgt ggctgcccct gtcccgccgc
      421 ccgcgggcgt gcttggggcc ctcgggcccg cggtgctgat cccggttctc cgccacgcct
      481 gcccacccta gcgctctatg tcccgggggc gcggccatgg aggtggtggg cgacttcgag
      541 tactgcaagc gggacctcgt gggacacggg gccttcgctg tggtcttccg ggggcggcac
      601 cgccagaaaa ctgattggga ggtggctatt aaaagtatta ataaaaagaa cttgtcaaaa
      661 tcacaaattc tgcttggaaa ggaaataaaa atcttaaagg agcttcagca tgaaaacatc
      721 gtagcgctct atgatgttca ggaattgccc aactctgtct ttctggtgat ggagtattgc
      781 aatggtggag acctggcaga ttatttgcaa gctaaaggaa ctctgagtga agatactatc
      841 agagtgtttc tccatcagat tgcggcagcc atgcgaatcc tgcacagcaa agggataatc
      901 cacagggatc tcaaaccaca gaatatcctg ttgtcttatg ccaatcgaag gaagtcgaat
      961 gtcagtggta ttcgtattaa aatagctgat tttggtttcg cacggtacct acatagtaac
     1021 acaatggcag cgacactgtg tggatcccca atgtacatgg ctcccgaggt tattatgtct
     1081 caacattatg atgctaaggc agatttatgg agcataggaa cagtgatcta tcaatgccta
     1141 gttggaaaac caccttttca ggctaatagt cctcaggacc taaggatgtt ttatgaaaaa
     1201 aacaggagct taatgcctag tattcccaga gaaacatcac cttacttggc taatctcctt
     1261 ttgggtttgc ttcagagaaa tcaaaaggat agaatggact ttgaagcatt tttcagccat
     1321 cctttccttg agcaagttcc agttaaaaaa tcttgcccag tcccagtgcc tgtgtattct
     1381 ggccctgtcc ctggaagctc ctgcagcagc tcaccatctt gtcgctttgc ttctccacca
     1441 tcccttccag atatgcagca tattcaggaa gaaaacttat cctccccacc gttgggtcct
     1501 cccaactatc tacaggtgtc caaagactct gcgagtaata gtagcaagaa ctcttcttgt
     1561 gacacggatg actttgtttt ggttccacac aacatctcgt cagaccactc atatgacatg
     1621 ccaatgggga ctacggccag acgtgcttca aatgaattct ttatgtgtgg agggcagtgt
     1681 caacctactg tgtcacctca cagcgaaaca gccccaattc cagttcctac tcaagtaagg
     1741 aattatcagc gcatagaaca gaatcttata tccactgcca gctctggcac aaacccacat
     1801 ggttctccaa gatctgcagt agtacgaagg tctaatacca gccccatggg cttcctccgg
     1861 gttgggtcct gctcccctgt accaggagac acagtgcaga caggaggacg aagactctct
     1921 actggctctt ccaggcctta ctcaccatcc cctttggttg gtaccattcc tgaacagttt
     1981 agtcagtgct gctgtggaca tcctcagggc catgaagcca ggagtaggca ctcctcaggt
     2041 tctccagtgc cacagaccca ggcaccacag tcactcttac tgggtgctag actgcagagt
     2101 gcacccaccc tcaccgatat ctatcagaac aagcagaagc tcagaaagca gcactctgac
     2161 cctgtgtgtc cgtcccatgc tggagctggg tatagttact cacctcagcc tagtcggcct
     2221 ggcagccttg ggacctctcc caccaagcac acggggtcct ctccacggaa ttctgactgg
     2281 ttctttaaaa ctcctttacc aacaatcatt ggctctccta ctaagactac agctcctttc
     2341 aaaatcccta aaacacaagc atcttctaac ctgttagcct tggttactcg tcatgggcct
     2401 gctgaaagcc agtccaaaga tgggaatgac cctcgtgagt gttcccactg cctctcagta
     2461 caaggaagcg agaggcatcg atctgagcag cagcagagca aggcagtgtt tggcagatct
     2521 gtcagtactg ggaagttatc agaacaacaa gtaaaggcac ctttaggtgg acaccagggc
     2581 agcacggata gtttaaacac agaacgacca atggatgtag ctcctgcagg agcctgtggt
     2641 gttatgctgg cattgccagc aggaacagca gcaagcgcca gagctgtcct cttcaccgtg
     2701 gggtctcctc cacacagtgc cacagccccc acttgtactc atatggtcct tcgaacaaga
     2761 accacctcag tggggtccag cagctcagga ggttccttgt gttctgcaag tggccgagta
     2821 tgtgtgggct cccctcctgg accagggttg ggctcttccc caccaggagc agagggagct
     2881 cccagcctaa gatacgtgcc ttatggtgct tcaccaccca gcctagaggg tctcatcacc
     2941 tttgaagccc ctgaactacc agaggagaca ctgatggagc gagagcacac agacacctta
     3001 cgccatctga acatgatgtt aatgtttact gagtgtgtgc tggacctgac ggcagtgagg
     3061 ggtgggaacc ctgagctgtg cacatctgct gtgtccttgt accagattca ggagagtgta
     3121 gttgtggacc agatcagcca gctaagcaaa gattgggggc gggtggagca gctggtgttg
     3181 tacatgaagg cagcacagct gctggcggct tccctgcatc tcgccaaagc tcaggtcaag
     3241 tctgggaagc tgagcccatc catggctgtg aaacaagttg ttaaaaatct gaatgaaaga
     3301 tacaaattct gcatcaccat gtgcaagaaa cttacagaaa agctgaatcg cttcttctcc
     3361 gataaacaga gatttattga tgaaatcaac agtgtgactg cagagaaact catctataat
     3421 tgtgctgtgg aaatggttca atctgcagcc ctggatgaga tgtttcagca gactgaagac
     3481 atcgtttatc gctaccacaa ggcagccctt cttttggaag gcttaagtaa gatcctgcag
     3541 gaccctacag atgttgaaaa tgtgcataag tataaatgta gtattgaaag aagattgtca
     3601 gcactctgct gtagcactgc aactgtgtga gtagcaggct tgtctgtgga ctggcatgga
     3661 acaggaggtg atacatttgg gattacatct tggttctgtc acccatccca ggacagtgtg
     3721 gtgactacca aagaacaagc agcagcttaa gaaggaagaa caatacaaaa ctactacata
     3781 ttgtagaaaa cctgccttat tggagaagtc actccccctt tcctttctct tcatagaagc
     3841 agaacaaaaa gttttccaca tggctcaagt tatttgaacc tggcaaataa taaatgtacc
     3901 ttagaactag catcataagt acagttattc ttgtggataa ttaaacagga aacaaagtga
     3961 gtggcttcat tcagctctct gagcaataca tgaaattccg tgttttgcta aagcatacac
     4021 aagcaaaagc gtatacagct cgtccagacg atctgaggtt tggggtaagt ttgtctgaat
     4081 ctgagcctgc atctttaaac agctcaggag gaggaatctt aagaagaaac aaaaggtgac
     4141 tcttggatga attgtgaaat cttcaacttg atctaatgtg gacatgattt taatcttcca
     4201 aaaatctttc atattgcact aatttattaa aataactgtg tattggattt tgcaatttaa
     4261 aactaactga ggcacaatgg acttgtttaa atattttact tgattatata catgtccttt
     4321 tcagaattca tgtgtaatct ccactgaact tttaaatggt tggaaattgc gttcatgtga
     4381 acctttgcat ttttctcacc tgttatcttc accaacagat cttagtggaa ttttgagttg
     4441 ctggttgttt gcattttttg ttgtgcatgc agaatgtgca tcgactcctg tgatcttagg
     4501 tttactaaag gctaagttta tttgggcagt attagaaagc tatcatgaat caagaaatac
     4561 tcttgagaat tttaataggg ccaaatcaaa gtgatgaata atggcttgtt agtgatgtgg
     4621 agtttctaca tgaaattagt aagaaatgag gttcgttttc ccttaggaaa tgggcagctc
     4681 tctccagact aatgtgtact tctcagtgtt aaccctgagt tcaccatagc tagtcatggc
     4741 agatcagcac ctctccaaga atggttcctg tgttgtatat tatttggtat cttttactta
     4801 cctgcttgaa tacttgaata aaccattcac cggttttaat ccttttactt caaaacttac
     4861 acatactgac ctactctctg atagctgcac agaaactctt tggcgccaca cttgctttag
     4921 tgtgctgatt aaagttaaca gagaaaacat ggttttcatt tacttggtga acaaagtaat
     4981 gtaattttta cattatttat ctgtatgaaa ttccagcagt taatttgaac gtttatgtat
     5041 aggatgtttg tattcttagg tctttactac agtgtttcta cctctcattt gtaactgcat
     5101 tatcttcaaa ataggtaaaa cccactaagt cattgtggaa tagccttttt taaattgctt
     5161 gtacaaatgt atattaaggt taaataaaac tgacagtgtt tttaggttat agttgggtta
     5221 atatgaaggc ttgtcaagcc agatgcttcc ttagagagtg ggttggaaac ttggccatca
     5281 atattctttg ccctgctcca ggattcaaaa ctcttggaag ctgtcatgca ggctcctaca
     5341 gacaagacta tatccctcct tatattagtg gtaaaatgcc ttctgtaatt tttacactaa
     5401 attctttcat gttctcccaa ttaccccgtt tatctcagtt gattttccaa gtaactagat
     5461 gtagttggcc tcctcttcta ccacttttta aaaatataat atgaacaagt ttggagaggg
     5521 taaggttggt gtgaagacag gaagtaggca agtgttgaaa ctgcactgtg actctcaagc
     5581 tcttcttgta tgacaaaggt cttgtaggtg gtgtgtataa agcagtgatg tctcagcagt
     5641 ggagaacagc tgtaaactta gtgagtaacg gttctgatat actaccatta tcaaggctaa
     5701 ttgtttaaag aaaagtttgc cttgattata gcaataataa ataaatgctt tatgtttctg
     5761 tatttttatt tcatatcatg tatctcataa aatggaatta gacaagttca cac
//
