LOCUS       NM_009469               5215 bp    mRNA    linear   ROD 12-NOV-2024
DEFINITION  Mus musculus unc-51 like kinase 1 (Ulk1), transcript variant 2,
            mRNA.
ACCESSION   NM_009469 XM_990757 XM_990781 XM_990811
VERSION     NM_009469.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5215)
  AUTHORS   Dong,M.Z., Ouyang,Y.C., Gao,S.C., Gu,L.J., Guo,J.N., Sun,S.M.,
            Wang,Z.B. and Sun,Q.Y.
  TITLE     Protein phosphatase 4 maintains the survival of primordial
            follicles by regulating autophagy in oocytes
  JOURNAL   Cell Death Dis 15 (9), 658 (2024)
   PUBMED   39245708
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5215)
  AUTHORS   Ghazi,P.C., O'Toole,K.T., Srinivas Boggaram,S., Scherzer,M.T.,
            Silvis,M.R., Zhang,Y., Bogdan,M., Smith,B.D., Lozano,G.,
            Flynn,D.L., Snyder,E.L., Kinsey,C.G. and McMahon,M.
  TITLE     Inhibition of ULK1/2 and KRASG12C controls tumor growth in
            preclinical models of lung cancer
  JOURNAL   Elife 13, 96992 (2024)
   PUBMED   39213022
  REMARK    GeneRIF: Inhibition of ULK1/2 and KRAS[G12C] controls tumor growth
            in preclinical models of lung cancer.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5215)
  AUTHORS   Huang,T., Zhang,C., Ren,J., Shuai,Q., Li,X., Li,X., Xie,J. and
            Xu,J.
  TITLE     FTO-mediated m 6A demethylation of ULK1 mRNA promotes autophagy and
            activation of hepatic stellate cells in liver fibrosis
  JOURNAL   Acta Biochim Biophys Sin (Shanghai) 56 (10), 1509-1520 (2024)
   PUBMED   39175431
  REMARK    GeneRIF: FTO-mediated m [6]A demethylation of ULK1 mRNA promotes
            autophagy and activation of hepatic stellate cells in liver
            fibrosis.
REFERENCE   4  (bases 1 to 5215)
  AUTHORS   Guan,Y., Spaulding,H., Yu,Q., Zhang,M., Willoughby,O., Drake,J.C.
            and Yan,Z.
  TITLE     Ulk1 phosphorylation at S555 is not required for endurance
            training-induced improvements in exercise and metabolic capacity in
            mice
  JOURNAL   J Appl Physiol (1985) 137 (2), 223-232 (2024)
   PUBMED   38900860
  REMARK    GeneRIF: Ulk1 phosphorylation at S555 is not required for endurance
            training-induced improvements in exercise and metabolic capacity in
            mice.
REFERENCE   5  (bases 1 to 5215)
  AUTHORS   Jia,M., Dong,Z., Dong,W., Yang,B., He,Y., Wang,Y. and Wang,J.
  TITLE     DDIT3 deficiency accelerates bone remodeling during bone healing by
            enhancing osteoblast and osteoclast differentiation through
            ULK1-mediated autophagy
  JOURNAL   Bone 182, 117058 (2024)
   PUBMED   38408589
  REMARK    GeneRIF: DDIT3 deficiency accelerates bone remodeling during bone
            healing by enhancing osteoblast and osteoclast differentiation
            through ULK1-mediated autophagy.
REFERENCE   6  (bases 1 to 5215)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
REFERENCE   7  (bases 1 to 5215)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   8  (bases 1 to 5215)
  AUTHORS   Kannan,K., Kaminski,N., Rechavi,G., Jakob-Hirsch,J., Amariglio,N.
            and Givol,D.
  TITLE     DNA microarray analysis of genes involved in p53 mediated
            apoptosis: activation of Apaf-1
  JOURNAL   Oncogene 20 (26), 3449-3455 (2001)
   PUBMED   11423996
REFERENCE   9  (bases 1 to 5215)
  AUTHORS   Tomoda,T., Bhatt,R.S., Kuroyanagi,H., Shirasawa,T. and Hatten,M.E.
  TITLE     A mouse serine/threonine kinase homologous to C. elegans UNC51
            functions in parallel fiber formation of cerebellar granule neurons
  JOURNAL   Neuron 24 (4), 833-846 (1999)
   PUBMED   10624947
REFERENCE   10 (bases 1 to 5215)
  AUTHORS   Yan,J., Kuroyanagi,H., Kuroiwa,A., Matsuda,Y., Tokumitsu,H.,
            Tomoda,T., Shirasawa,T. and Muramatsu,M.
  TITLE     Identification of mouse ULK1, a novel protein kinase structurally
            related to C. elegans UNC-51
  JOURNAL   Biochem Biophys Res Commun 246 (1), 222-227 (1998)
   PUBMED   9600096
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC057121.1.
            
            On or before May 4, 2006 this sequence version replaced
            XM_990811.1, XM_990781.1, XM_990757.1, NM_009469.2.
            
            Transcript Variant: This variant (2) uses an alternate in-frame
            splice junction compared to variant 1. The resulting isoform (2)
            has the same N- and C-termini but is shorter compared to isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC057121.1, AF072370.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
FEATURES             Location/Qualifiers
     source          1..5215
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 53.7 cM"
     gene            1..5215
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /note="unc-51 like kinase 1"
                     /db_xref="GeneID:22241"
                     /db_xref="MGI:MGI:1270126"
     exon            1..468
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     CDS             358..3513
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /EC_number="2.7.11.1"
                     /note="isoform 2 is encoded by transcript variant 2;
                     serine/threonine-protein kinase ULK1;
                     serine/threonine-protein kinase Unc51.1"
                     /codon_start=1
                     /product="serine/threonine-protein kinase ULK1 isoform 2"
                     /protein_id="NP_033495.2"
                     /db_xref="CCDS:CCDS19532.1"
                     /db_xref="GeneID:22241"
                     /db_xref="MGI:MGI:1270126"
                     /translation="MEPGRGGVETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVA
                     VKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLAD
                     YLHTMRTLSEDTVRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPGGRRANPSNIR
                     VKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGK
                     APFQASSPQDLRLFYEKNKTLVPAIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHP
                     FLDASTPIKKSPPVPVPSYPSSGSGSSSSSSSASHLASPPSLGEMPQLQKTLTSPADA
                     AGFLQGSRDSGGSSKDSCDTDDFVMVPAQFPGDLVAEAASAKPPPDSLLCSGSSLVAS
                     AGLESHGRTPSPSPTCSSSPSPSGRPGPFSSNRYGASVPIPVPTQVHNYQRIEQNLQS
                     PTQQQTARSSAIRRSGSTSPLGFGRASPSPPSHTDGAMLARKLSLGGGRPYTPSPQVG
                     TIPERPSWSRVPSPQGADVRVGRSPRPGSSVPEHSPRTTGLGCRLHSAPNLSDFHVVR
                     PKLPKPPTDPLGATFSPPQTSAPQPCPGLQSCRPLRGSPKLPDFLQRSPLPPILGSPT
                     KAGPSFDFPKTPSSQNLLTLLARQGVVMTPPRNRTLPDLSEASPFHGQQLGSGLRPAE
                     DTRGPFGRSFSTSRITDLLLKAAFGTQASDSGSTDSLQEKPMEIAPSAGFGGTLHPGA
                     RGGGASSPAPVVFTVGSPPSGATPPQSTRTRMFSVGSSSSLGSTGSSSARHLVPGACG
                     EAPELSAPGHCCSLADPLAANLEGAVTFEAPDLPEETLMEQEHTETLHSLRFTLAFAQ
                     QVLEIAALKGSASEAAGGPEYQLQESVVADQISQLSREWGFAEQLVLYLKVAELLSSG
                     LQTAIDQIRAGKLCLSSTVKQVVRRLNELYKASVVSCQGLSLRLQRFFLDKQRLLDGI
                     HGVTAERLILSHAVQMVQSAALDEMFQHREGCVPRYHKALLLLEGLQHTLTDQADIEN
                     IAKCKLCIERRLSALLSGVYA"
     exon            469..561
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     exon            562..603
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     exon            604..636
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     exon            637..673
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     exon            674..847
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     exon            848..921
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     exon            922..1023
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1024..1082
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1083..1165
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1166..1216
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1217..1305
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1306..1453
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1454..1514
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1515..1604
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1605..1730
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1731..1876
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1877..1963
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1964..2232
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     exon            2233..2426
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     exon            2427..2536
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     exon            2537..2680
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     exon            2681..2871
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     exon            2872..3044
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     exon            3045..3163
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     exon            3164..3321
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     exon            3322..3457
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     exon            3458..5196
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5178..5183
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /note="hexamer: AATAAA"
     polyA_site      5196
                     /gene="Ulk1"
                     /gene_synonym="mKIAA0722; Unc51.1"
                     /note="major polyA site"
ORIGIN      
        1 ccgaggcccg ggtgccgcgg atcttttgtt tccctgcggg gctccgagcc gcatcgtcag
       61 tcaggcccgg acttggagct ggagtgtgtc agagctgagt cccgagtcgg accgggtccc
      121 gactgtcagc gccgggaggg taccgaggag gacgccgagg gagcgcgccc ctccgtccgc
      181 cggcctgtgg gactgggacc cggctcaggc ctgcccgatg gggcacgggg ccctggcgat
      241 gagcccgcgc ctccgtcccc gcgtacgcgg cccgccggcc tccgcctgag cccagcgcac
      301 cccgtagcgc cgccccgggg cccgagcccg ggctcgcgcc cccggcccgc gcgcgctatg
      361 gagccgggcc gcggcggcgt cgagaccgtg ggcaagttcg agttctctcg caaggacctg
      421 attggacacg gcgccttcgc ggtggtcttc aagggtcgac accgcgagaa gcacgacctg
      481 gaggtggccg tcaaatgcat taacaagaag aaccttgcca agtcccaaac actgctggga
      541 aaggaaatca aaatcctgaa ggaactaaag cacgaaaaca tcgtggcgct gtatgacttc
      601 caggaaatgg ctaattctgt ctacctggtc atggagtatt gtaatggtgg agacctggct
      661 gactacctgc acactatgcg cacactgagt gaagacactg tcaggctttt cctacagcag
      721 atcgctggcg ccatgcggct gctgcacagc aagggcatca tccaccggga cctgaagccc
      781 caaaacatcc tgctgtccaa ccctgggggc cgccgggcca accccagcaa catccgagtc
      841 aagattgctg actttggatt cgctcggtac ctccagagca acatgatggc ggccacactc
      901 tgtggttctc ctatgtacat ggctcctgag gtcattatgt cccagcacta cgatggaaag
      961 gctgacctgt ggagcattgg caccattgtc taccagtgtc tgacagggaa ggcccctttt
     1021 caggccagca gccctcagga tttgcgcctg ttttatgaga agaacaagac actagttcct
     1081 gccatccccc gggagacatc agctcccctg cggcagctgc tcctggctct gttgcagcgg
     1141 aaccacaagg accgcatgga ctttgatgaa tttttccacc accctttctt ggatgccagc
     1201 acccccatca agaaatcccc acctgtgcct gtgccctcat atccaagctc agggtctggc
     1261 agcagctcca gcagcagctc tgcctcccac ctggcctctc caccgtccct gggggagatg
     1321 ccacagctac agaagaccct tacctcccca gccgatgctg ctggctttct tcagggctcc
     1381 cgggactctg gtggcagcag caaagactcc tgtgacacag atgactttgt catggtccca
     1441 gcccagtttc caggtgatct agttgctgag gcagccagtg ccaagccccc acctgatagc
     1501 ctgctgtgta gtgggagctc attggtggcc tctgctggcc tagagagcca cggccgtacc
     1561 ccctctccct ctccgacctg cagcagctct cccagcccct ctggccggcc tggccccttc
     1621 tccagcaaca ggtacggtgc ctcggtcccc attcctgtcc ccactcaggt gcacaattac
     1681 cagcgcatcg agcaaaacct gcaatcgccc actcaacagc agacagccag gtcctctgcc
     1741 atccgaaggt cagggagcac cagccccctg ggctttggcc gggccagccc atcacccccc
     1801 tcccacaccg atggagccat gctggccagg aagctgtcac ttggaggtgg ccgtccctac
     1861 acaccttctc cccaagtggg aaccatccca gagcgaccca gctggagcag agtgccctcc
     1921 ccacaaggag ctgatgtgcg ggttggcagg tcaccacgac ccggttcctc tgtgcctgag
     1981 cactctccaa gaaccactgg gctgggctgc cgcctgcaca gtgcccctaa cctgtccgac
     2041 ttccatgttg tgcgtcccaa gctgcctaag cccccaacag acccactggg agccaccttt
     2101 agcccacccc agaccagcgc accccagcca tgcccagggc tacagtcttg ccggccactg
     2161 cgtggctcac ctaagctgcc tgacttccta cagcggagtc ccctaccccc catcctaggc
     2221 tctcctacca aggccgggcc ctcctttgac ttccccaaaa cccccagctc tcagaatttg
     2281 ctgaccctgt tggctaggca gggggtagta atgacaccac ctcggaaccg tacactgcct
     2341 gacctctccg aggccagtcc tttccatggc cagcagctgg gctctggcct tcggcccgct
     2401 gaagacaccc ggggtccctt tggacggtcc ttcagcacca gccgcattac ggacctgctg
     2461 cttaaggctg catttgggac tcaggcctct gactcaggca gcacagacag cctacaggag
     2521 aaacctatgg agattgctcc ctctgctggc tttggaggga ctctgcatcc aggagctcgt
     2581 ggtggagggg ccagcagccc agcacctgtg gtatttactg taggctcccc acccagtggt
     2641 gccaccccac cccagagtac ccgtaccaga atgttctcag tgggctcttc cagctccctg
     2701 ggctctactg gctcctcctc tgcccgccac ttagtgcctg gggcctgtgg agaggccccg
     2761 gagctttctg ccccaggcca ctgctgtagc cttgctgacc cccttgctgc caacttggag
     2821 ggggctgtga ccttcgaggc tcctgacctc ccagaggaga ccctcatgga gcaagagcac
     2881 acggaaaccc tacacagtct gcgcttcaca ctagcgtttg cacagcaagt tctggagatt
     2941 gcagccctga agggaagtgc cagtgaggcc gccggtggcc ctgagtacca gctccaggaa
     3001 agtgtggtgg ctgaccagat cagtcagttg agccgagagt ggggctttgc agagcaactg
     3061 gttctgtact tgaaggtggc tgagctgctg tcctcaggcc tacagactgc cattgaccag
     3121 attcgagctg gcaaactctg cctttcatct actgtgaagc aggtggtacg cagactaaat
     3181 gagctgtaca aggccagcgt ggtatcctgc cagggcctca gcttgcgact tcagcgcttc
     3241 tttctggaca aacaacggct gctggacggg atccatggtg tcactgcaga gcggctcatc
     3301 ctcagccatg ctgtgcaaat ggtacaatca gctgcccttg atgagatgtt ccagcaccga
     3361 gagggctgtg taccgagata tcacaaagcc ctgctattgc tggaggggtt gcagcacact
     3421 ctcacggacc aggcagacat tgagaacatt gccaaatgca agctgtgcat tgagaggaga
     3481 ctctcggccc tgctgagtgg tgtctatgcc tgactacctg ctgccaacct gcagggtagg
     3541 gtctgagacc tggcagactg tcctcaacac tgatcagatc cgatggtgct gagactgctg
     3601 ccagccaact ccagcaggga tgctccacag tggacctgtg cagactggtg caactcttgc
     3661 ttcctagact gccagtctct gctggcaggt agacatcaga gtgccagggg tcccttgccc
     3721 actgggacag gagtttctga acatattctt cctagctggc tccctggcaa gcaggtatgg
     3781 tgccgagaag tggcacctgc cacctgaaga gcccatggca gccctgtgtc aggcaagggc
     3841 ctgagaccgt tgctgactcc aagccaaagc aagcttttcc tcacagttca cttgccccat
     3901 tgcttgtcca agaaaaaagg gtatggtctt ctggccccct gttctctcta ggaacttctc
     3961 cctctgagac tacttaccca gctttgtaag tcaccggagc actttatgca tacagagact
     4021 ggagaaccta gccagcagtg cagactgctg ggaacctgcc tcctgttcct ggctttcgtc
     4081 ctccaagacg ctgtatagat gcagaccaca tctttgtgta taaaaagccc agtgttcacc
     4141 tcctcctgtg tctggtcttt ggaggaaagc aacaggcttg cctcctgagg gagagatagt
     4201 cctcacgttt aaatgttcat tagggacaga cagttcattg tgtgaagcac cacccatgct
     4261 tgttaaaact cctcaacttc cacactttac tcctaagatg tgtctccacc ctcccaactc
     4321 agtttttgtt cataaaagga aacttcagat gtttaaggat tgaaagggcg gaggcagggc
     4381 aggccaggta tcacactgga tgttgtcctt gtaggagacg gtgcccgctg tgtggctgag
     4441 gctgtagcat gtgccagagc gagtgtgctg ctggctatct ctattaactt tccctggaag
     4501 ggcggcagaa aaggcagtgc ccaggtgccg tcctccctgt gcagtggagg tgtgggtgaa
     4561 gaataacata tgcaaacatg tcccctgtgg agctttcctg tcagtctggc tcctgtgctt
     4621 ggtggccttc aggatctgtg ctgaagctcg tcttccaggc tccagggtgg acacatgcta
     4681 ataccttccc agcctccctg acctgccagt cctttgtcac ggctctgttc atgcatactt
     4741 gaaagtatct gagtgtccac aagctgatgt ggggtttcag agttataggc cacacacaca
     4801 cacacacaca cacgtttttc tttgcaatac ttgaaatatt gccactgtgc ttggttgtac
     4861 aagagttgta caagaaagca gatctctaag accagtctct tccttagtca ccctatgacc
     4921 tcccttgcat gtaacatgtt gtatttattg ctttgtggcc aactggaacc cagagccacc
     4981 agggaggcta gtgcagggat tcctgaccca ccacctggtt cctgaaaggc tcctgggtgg
     5041 ctgtgtgtgt gtgtggctgg ctgtgtgtgg tatgagccaa acctgctcat gaaagcagtg
     5101 ctcaggcctg tcaattttaa gatgaatttt gtgagtctcc cccttttgtg tttcactgtg
     5161 tcatatcagt ttaagaaaat aaaaattgga attattaaaa aaaaaaaaaa aaaaa
//
