LOCUS       NM_010633               7872 bp    mRNA    linear   ROD 13-MAY-2024
DEFINITION  Mus musculus U2AF homology motif (UHM) kinase 1 (Uhmk1), transcript
            variant 1, mRNA.
ACCESSION   NM_010633 XM_003689331
VERSION     NM_010633.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7872)
  AUTHORS   Moreno-Aguilera,M., Neher,A.M., Mendoza,M.B., Dodel,M.,
            Mardakheh,F.K., Ortiz,R. and Gallego,C.
  TITLE     KIS counteracts PTBP2 and regulates alternative exon usage in
            neurons
  JOURNAL   Elife 13, e96048 (2024)
   PUBMED   38597390
  REMARK    GeneRIF: KIS counteracts PTBP2 and regulates alternative exon usage
            in neurons.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7872)
  AUTHORS   Feng,X., Ma,D., Zhao,J., Song,Y., Zhu,Y., Zhou,Q., Ma,F., Liu,X.,
            Zhong,M., Liu,Y., Xiong,Y., Qiu,X., Zhang,Z., Zhang,H., Zhao,Y.,
            Zhang,K., Hong,X. and Zhang,Z.
  TITLE     UHMK1 promotes gastric cancer progression through reprogramming
            nucleotide metabolism
  JOURNAL   EMBO J 39 (5), e102541 (2020)
   PUBMED   31975428
  REMARK    GeneRIF: UHMK1 promotes gastric cancer progression through
            reprogramming nucleotide metabolism.
REFERENCE   3  (bases 1 to 7872)
  AUTHORS   Scekic-Zahirovic,J., Sendscheid,O., El Oussini,H., Jambeau,M.,
            Sun,Y., Mersmann,S., Wagner,M., Dieterle,S., Sinniger,J.,
            Dirrig-Grosch,S., Drenner,K., Birling,M.C., Qiu,J., Zhou,Y., Li,H.,
            Fu,X.D., Rouaux,C., Shelkovnikova,T., Witting,A., Ludolph,A.C.,
            Kiefer,F., Storkebaum,E., Lagier-Tourenne,C. and Dupuis,L.
  TITLE     Toxic gain of function from mutant FUS protein is crucial to
            trigger cell autonomous motor neuron loss
  JOURNAL   EMBO J 35 (10), 1077-1097 (2016)
   PUBMED   26951610
REFERENCE   4  (bases 1 to 7872)
  AUTHORS   Pedraza,N., Ortiz,R., Cornado,A., Llobet,A., Aldea,M. and
            Gallego,C.
  TITLE     KIS, a kinase associated with microtubule regulators, enhances
            translation of AMPA receptors and stimulates dendritic spine
            remodeling
  JOURNAL   J Neurosci 34 (42), 13988-13997 (2014)
   PUBMED   25319695
  REMARK    GeneRIF: The absence of KIS results in a significant decrease in
            AMPA receptors in dendritic spines.
REFERENCE   5  (bases 1 to 7872)
  AUTHORS   Manceau,V., Kremmer,E., Nabel,E.G. and Maucuer,A.
  TITLE     The protein kinase KIS impacts gene expression during development
            and fear conditioning in adult mice
  JOURNAL   PLoS One 7 (8), e43946 (2012)
   PUBMED   22937132
  REMARK    GeneRIF: disregulation of gene expression due to KIS inactivation
            affects specific brain functions.
REFERENCE   6  (bases 1 to 7872)
  AUTHORS   Cobellis,G., Nicolaus,G., Iovino,M., Romito,A., Marra,E.,
            Barbarisi,M., Sardiello,M., Di Giorgio,F.P., Iovino,N., Zollo,M.,
            Ballabio,A. and Cortese,R.
  TITLE     Tagging genes with cassette-exchange sites
  JOURNAL   Nucleic Acids Res 33 (4), e44 (2005)
   PUBMED   15741177
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 7872)
  AUTHORS   Bieche,I., Manceau,V., Curmi,P.A., Laurendeau,I., Lachkar,S.,
            Leroy,K., Vidaud,D., Sobel,A. and Maucuer,A.
  TITLE     Quantitative RT-PCR reveals a ubiquitous but preferentially neural
            expression of the KIS gene in rat and human
  JOURNAL   Brain Res Mol Brain Res 114 (1), 55-64 (2003)
   PUBMED   12782393
REFERENCE   8  (bases 1 to 7872)
  AUTHORS   Boehm,M., Yoshimoto,T., Crook,M.F., Nallamshetty,S., True,A.,
            Nabel,G.J. and Nabel,E.G.
  TITLE     A growth factor-dependent nuclear kinase phosphorylates p27(Kip1)
            and regulates cell cycle progression
  JOURNAL   EMBO J 21 (13), 3390-3401 (2002)
   PUBMED   12093740
  REMARK    GeneRIF: Endogenous mouse KIS was detected mainly in the nucleus of
            asynchronously growing cells.  During serum starvation, its
            expression was reduced.
REFERENCE   9  (bases 1 to 7872)
  AUTHORS   Maucuer,A., Ozon,S., Manceau,V., Gavet,O., Lawler,S., Curmi,P. and
            Sobel,A.
  TITLE     KIS is a protein kinase with an RNA recognition motif
  JOURNAL   J Biol Chem 272 (37), 23151-23156 (1997)
   PUBMED   9287318
REFERENCE   10 (bases 1 to 7872)
  AUTHORS   Maucuer,A., Camonis,J.H. and Sobel,A.
  TITLE     Stathmin interaction with a putative kinase and coiled-coil-forming
            protein domains
  JOURNAL   Proc Natl Acad Sci U S A 92 (8), 3100-3104 (1995)
   PUBMED   7724523
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC123650.7 and BC058732.1.
            
            On Feb 14, 2018 this sequence version replaced NM_010633.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14995048.2182488.1,
                                           SRR13861890.84678.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-14                AC123650.7         89264-89277
            15-2038             BC058732.1         1-2024
            2039-7872           AC123650.7         105416-111249
FEATURES             Location/Qualifiers
     source          1..7872
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 76.84 cM"
     gene            1..7872
                     /gene="Uhmk1"
                     /gene_synonym="4732477C12Rik; 4930500M09Rik;
                     C820018A03Rik; KIS; Kist; P-CIP2"
                     /note="U2AF homology motif (UHM) kinase 1"
                     /db_xref="GeneID:16589"
                     /db_xref="MGI:MGI:1341908"
     exon            1..435
                     /gene="Uhmk1"
                     /gene_synonym="4732477C12Rik; 4930500M09Rik;
                     C820018A03Rik; KIS; Kist; P-CIP2"
                     /inference="alignment:Splign:2.1.0"
     CDS             168..1427
                     /gene="Uhmk1"
                     /gene_synonym="4732477C12Rik; 4930500M09Rik;
                     C820018A03Rik; KIS; Kist; P-CIP2"
                     /EC_number="2.7.11.1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     kinase interacting with leukemia-associated gene
                     (stathmin); serine/threonine-protein kinase Kist; U2AF
                     homology motif kinase 1; kinase interacting with stathmin;
                     PAM COOH-terminal interactor protein 2"
                     /codon_start=1
                     /product="serine/threonine-protein kinase Kist isoform 1"
                     /protein_id="NP_034763.3"
                     /db_xref="CCDS:CCDS15468.1"
                     /db_xref="GeneID:16589"
                     /db_xref="MGI:MGI:1341908"
                     /translation="MAGSGCAWGAEPPRFLEAFGRLWQVQSRLGSGSSASVYRVRCCG
                     TPGSPPGALKQFLPPGTTGAAASAAEYGFRKERAALEQLQGHRNIVTLYGVFTIHFSP
                     NVPSRCLLLELLDVSVSELLLYSSHQGCSMWMIQHCARDVLEALAFLHHEGYVHADLK
                     PRNILWSAENECFKLIDFGLSFKEGNQDVKYIQTDGYRAPEAELQNCLAQAGLQSDTE
                     CTSAVDLWSLGIILLEMFSGMKLKHTVRSQEWKANSSAIIDHIFASKAVVNAAIPAYH
                     LRDLIKSMLHDDPGRRIPAEMALCSPFFSIPFAPHIEDLVMLPTPVLRLLNVLDDDYL
                     ENEDEYEDVVEDVKEECQKYGPVVSLLVPKENPGRGQVFVEYANAGDSKAAQKLLTGR
                     MFDGKFVVATFYPLSAYKRGYLYQTLL"
     exon            436..728
                     /gene="Uhmk1"
                     /gene_synonym="4732477C12Rik; 4930500M09Rik;
                     C820018A03Rik; KIS; Kist; P-CIP2"
                     /inference="alignment:Splign:2.1.0"
     exon            729..920
                     /gene="Uhmk1"
                     /gene_synonym="4732477C12Rik; 4930500M09Rik;
                     C820018A03Rik; KIS; Kist; P-CIP2"
                     /inference="alignment:Splign:2.1.0"
     exon            921..1015
                     /gene="Uhmk1"
                     /gene_synonym="4732477C12Rik; 4930500M09Rik;
                     C820018A03Rik; KIS; Kist; P-CIP2"
                     /inference="alignment:Splign:2.1.0"
     exon            1016..1092
                     /gene="Uhmk1"
                     /gene_synonym="4732477C12Rik; 4930500M09Rik;
                     C820018A03Rik; KIS; Kist; P-CIP2"
                     /inference="alignment:Splign:2.1.0"
     exon            1093..1191
                     /gene="Uhmk1"
                     /gene_synonym="4732477C12Rik; 4930500M09Rik;
                     C820018A03Rik; KIS; Kist; P-CIP2"
                     /inference="alignment:Splign:2.1.0"
     exon            1192..1280
                     /gene="Uhmk1"
                     /gene_synonym="4732477C12Rik; 4930500M09Rik;
                     C820018A03Rik; KIS; Kist; P-CIP2"
                     /inference="alignment:Splign:2.1.0"
     exon            1281..7872
                     /gene="Uhmk1"
                     /gene_synonym="4732477C12Rik; 4930500M09Rik;
                     C820018A03Rik; KIS; Kist; P-CIP2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7852..7857
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Uhmk1"
                     /gene_synonym="4732477C12Rik; 4930500M09Rik;
                     C820018A03Rik; KIS; Kist; P-CIP2"
                     /note="hexamer: AATAAA"
     polyA_site      7871
                     /gene="Uhmk1"
                     /gene_synonym="4732477C12Rik; 4930500M09Rik;
                     C820018A03Rik; KIS; Kist; P-CIP2"
                     /note="major polyA site"
ORIGIN      
        1 gcactccggc ttccggtgtc atggcggcct gaggtccggg gagtcggtcg gagcgctgca
       61 ggcccctccc tgcggagcgg cgggtccggg cggggatgtg acggcgggcg ccgcgggcct
      121 gcctggcgcg tcgtgtcggc tcgcgtgtcc tcggcccagc ccgcaccatg gcggggtccg
      181 gctgcgcgtg gggcgccgag ccgccgcgct tcctggaggc cttcgggcgg ctgtggcagg
      241 tccagagccg cctgggcagc ggctcgtcgg cctcggtgta ccgggtgcgg tgctgcggta
      301 ccccgggctc gccccccggc gccctcaagc agttcctgcc tccgggaacc accggggctg
      361 cggcctcggc cgcggagtat ggtttccgca aagagagggc ggcgctggag cagttgcagg
      421 gtcacaggaa catcgtgact ttatatggag tctttaccat acacttctct cccaatgtgc
      481 catcacgctg tctgctgctt gaactcctgg atgtcagtgt ttcggaattg cttttatatt
      541 ccagtcatca gggctgctcc atgtggatga tacagcactg tgcccgagat gttctggagg
      601 ccctcgcttt tcttcaccat gagggctacg tccatgcaga cctcaaacca cgaaacatcc
      661 tgtggagtgc ggagaatgag tgttttaagc ttattgactt tggactcagc ttcaaagaag
      721 gcaatcagga cgtaaagtat attcagacag acgggtatcg cgctcctgaa gcagagctgc
      781 agaactgctt ggcccaggcc ggcctgcaga gtgatacaga atgtacctca gctgttgatc
      841 tgtggagcct cggaatcatt ttactggaaa tgttctcagg aatgaagctg aaacatacag
      901 tcagatctca ggaatggaag gcaaacagtt ctgctattat tgatcatata tttgccagta
      961 aagcagtggt gaatgccgca attccagcct atcacctcag agaccttatc aaaagcatgc
     1021 ttcatgatga cccgggcaga agaatccctg ctgagatggc attgtgcagc ccattcttta
     1081 gcattccttt tgcccctcat attgaagatc tggtgatgct tccgactcca gtgctcaggc
     1141 tcctcaatgt gctggatgat gattaccttg aaaatgaaga tgaatatgaa gatgttgtag
     1201 aagatgtgaa agaggagtgt cagaaatatg gaccagtggt ttctctgctt gttccaaagg
     1261 aaaatcctgg cagaggacaa gtcttcgttg agtacgcgaa cgctggtgat tccaaagctg
     1321 ctcagaagtt gctgactggg aggatgtttg acgggaagtt tgttgtggct acattctacc
     1381 cgctgagtgc ctacaagagg ggatatcttt atcaaacctt gctttaatca gtaacctaag
     1441 gactacttcc tgtttctcct cttccatttc ttggattatt atattccaca gctgaatgca
     1501 ggagcacccc tttacccatt ttaaagggta ccttgtacat ttatttaatc ctactaatgt
     1561 gcagccattg cccagacagt gactgcattg caaacatggc actgagtagg acccgacctc
     1621 tcagctatac attgaggggg ttagagcacc catgtggcca ccctttattt gtgcagtagg
     1681 gcaggtgctg ctctttacta tgtaacctaa aaagatgtca tttcatgtga tgatgaagca
     1741 aagatgagtt gtttgtcata gtaaatacta ttaacaaatt tgttagggtt ggtgacatca
     1801 cagaatattt gtttgtattg tcaggtgtat ctccttgtta ttctagctgg cactggatgc
     1861 tctaataatg ttaagtcatt gtcaagcagc agttacctac cgtgttctta acaatgagtt
     1921 gtgaattttt ctaaaggagt actgtaggac ttaatattcc tccgaagaaa ctgcagtgag
     1981 cctatcaatg tttttaaaat tactattaag gcttttaaaa tagaaagctg atgcttgatc
     2041 ttgcacaatt tttatgtata gtgtgtatgc ttgagtgggt gtgcaggtgt gaaagactat
     2101 agagaatctg agtcagtgta ttttacagtg tgagtcttgt gagctaacac actctataac
     2161 catttcttcc taccggtttc acacctgaga gacttgggct ataggtttct tgaaagttgg
     2221 tctgacagat agaatgtaat tgacaagaga gttcattact gtaaagtgca gaacaaagtg
     2281 gagtctagac cagggttcca tgtagctctt cagagtgtaa gttaccctgt tctctgctct
     2341 actgtagacc caagattggc tcatctcttt tgtactgaac ctcttgtgat aattgtaaag
     2401 tttttccaga tgtgattctt tctgctataa tgggaaattg aaatggatca gataaaagtt
     2461 agatgcacag tgacgggaaa agagaagagt gcagagaagg cagctcatca cagaccctcc
     2521 tcccccatct gccctgctgc cctgccacct tcctcctttc cccgtcgcct ctgtctgcag
     2581 cctgagggca gtgtcccgag tcatcggctt ttgactgtaa gggaaaagaa aggttgatgt
     2641 attagaaggt tgaagtagaa aggaagaaaa ttcagtttct aaaagaacaa tagcaatcta
     2701 gtgtgtcctt gatagaggat gcctgttgcc acgagtttgt ggacacagat ggactgtggc
     2761 ttgagggata tgagtggggt tcttcctgct ctgtagtagt ttgccttgaa aggtgtaaac
     2821 gtaggaaact tttgtaaagc actgattata caagataacc cacagattgt acacttgtga
     2881 cagagttttt cctatttcct tacctgaatg aaagtgttat ttatttattt ttccttagga
     2941 aagagtgttt gtttctcttc ctgctggcag cctgcttata tagtctcttg tccatgctgt
     3001 tcaagttccc aaaaactcca ttaaaacttg cattttagag gttgaattat tttaccctgt
     3061 ttagacattt actgcccaac atttgtcagt ataatcaaat tgtcccgagc tcccacttag
     3121 gaagttacat ttggtgtaag gggatttgct gctgagttac ctctgctcgt ctctcgtggt
     3181 ccctgatgag tgtcttggga agaaggcttt ttcaggggtt cattgtgtgg ttggttttca
     3241 agtcaaactt gaagaacata gaatcagggc tgtgaagtcc taactaagct ttcctaaaac
     3301 ataaatattt acatgaggag ctgcttctgt ggtcattagt agcaggtctc tacgtttcta
     3361 ctgatgacca caagatacaa gtgaattctt ttgaagggca agtatggtta gcacatgttc
     3421 ccatatctca taaaaaagag atccttgcaa ataaactgca ggtaggctgc caagctttac
     3481 cgtgcagtat gctgctaaca ctgctgtact cacagcattc tgtgaacctc atccatgcag
     3541 atgtagctat gcacatgtgt agagttgaca ctgtagactt gttacagacg atgctagcca
     3601 gattttaagg gagctgagga agtaaatgag tgagcccgag taattacatt gagatcattg
     3661 aattaaatag tttatattga agtcacagac ttgaagacaa aagataacct gctatgattt
     3721 aaaccattgt gtgatagctc ttagcccatt ttaccaaaga ggacagctgc agattcctcc
     3781 tcctctgata ctatcaggac tttcatttta atatctttct taaactggga ccaaataata
     3841 ctacaaaaga tgcaattttc acaataaata tatgcacagg gattttaatt ccttgaaatt
     3901 attaaaatcc tagaattctc ttactaaggg gtaaagaagt gagcgctcat gttacttagt
     3961 ccctgtcttt gggggcaaat tttatctcag gtagtttttc tctccctatg ttaagatttg
     4021 tgcttccttc cttctctctt gcctccttcg gttcgtcttt attcttccaa agcactatac
     4081 agtgcacatt ttgtccctga ttaggcacag aaagcgattg cccgagggaa aacttggggt
     4141 tcttttgaag tatttggagg aggagacttg tagccattat caaaactata actctgtagt
     4201 tggaagagaa taatagtgct gggtacccca gaaaggtact gcctgcattt caccataagt
     4261 ctacatttat tatgactgga tactcttctt cctttgtgac cattggcaca gcgtctccct
     4321 ttgggaactc ttcctctctg ctaaactgat ctaaatttat ggctgctttt agaatcaaat
     4381 gactaacata gttctactca tctgtctctg ttttaattga gaggagtgtg gtcttctcgt
     4441 cgttatgtag ctgctgaaga tatgttaacc tgccagcaac tgtgctgcca cccagagaaa
     4501 ggtgccgaag tatgaggggc ataaggcttc cttctgtctt agtctagact ttccctcagg
     4561 caaggcacca cttagaggat aacgtagaag caggctgagg atcatgctgt tttatggctc
     4621 ttctgaatgt ggcaggtggc tgacaacttg gcatcattct tgttagttct cccgccagtt
     4681 tattaagcaa ttttattttt aacagtcgct gaaaatgagc atcatcgtgc ctacctggtg
     4741 ggaattatag cagtacagtg ggaggggacg cactggtgac catgcacttt acctagactc
     4801 tcacccaaag ggtacgggct gggctctttg ttcaggttag ggtacagatc gtgatgtttc
     4861 atctgttgga tgatgtgtag ctaaagttct gggcaagtca aatattaaac ctcacctggc
     4921 cgatgtccca ggggaactgc actgtcgcct ttctcttgga ataacttgga ttgattcgtg
     4981 tgagtccaga attttcttgg catacttttt aaaaaaatgt ataaaatgat cccagtttga
     5041 cttatttcag aattacatgt tgatggaaag gccagttatc tgtcacatct gattctggga
     5101 tctagtttca tttatcaggt tctttcttca gcacttactg atccagctct ctctttcttg
     5161 taagttgtgg acacttacac acccgtcctt ggtcacttct agttcaacag aatccccatt
     5221 tcttgaggtg ctcggcaagt tacctttctt tgcctagggt ttggcactct tcacttggcg
     5281 ttgcctgtct cctcaaatac acactgctct tgttgaggct gttgtgtgga gctcatctgg
     5341 tatgtttaga ttcctgggag gttgggtgtt cgagacaggg gttctctgtg tagccttgtc
     5401 tgtcctggaa ctagatttta gattcttaat catggagaag cttggatatt ttagttttta
     5461 gagtgtcccc atttttttta agaatgaatt ttgatccttt ctctacctta taacatagga
     5521 tggatcatga tttttatctt tgccacctcc cccagatggt ggtcaccagt gactattgct
     5581 ttacactgtg acaagcagtt ggcaggtact aggtattgaa gaaggtaaac aacttagagt
     5641 atttttgcta tgactttata ggagaaatga gctgtcaaaa gaaatatgta caagccaggg
     5701 agcatttagg atagaaagtt tttggagaca gggttttgca gtgtagccta gacaagcccc
     5761 cagctcagga tcttcctgct tcagcttccc aagtgctgct tgtcacagat gtgcaccatc
     5821 ttgcccagct ctgctaggaa gctgttctat agatggtcat aggtgttttt caggatataa
     5881 gactaacaca caagtttaca caccttttgt tgtcctgata gtgtctatag ctcagcgcgt
     5941 tccctgattc ttgtgctgct tacgggagtg attgttttaa acatgctgtt tttgtgcctt
     6001 tcagagagtc atagtcatgg tagctgtgtt tgctggagtt catgggaacc tcactaaagg
     6061 atggccggag tgctagactg gtagcagtca tgataatgcc aagaaaaagt ggtggctctt
     6121 ttgaaggctc agtgtgcttt gtgaactgag ttcttagtgt ttagtggcaa ggcaggcccg
     6181 cttttgcttg ccttacaagg tcatttcatc tctgttgtac aaaacacggc tgctcctgct
     6241 ctacctctct gttaaagcaa agcaagtcac attcttgaag actggaatgc ttactttttt
     6301 gtttgtttct tactgagaac cttgtataag cagctactac tgccaccttc agctcctgat
     6361 gatctgtgag cgggttctag ccattcttta agatccttgg tcagactccc ttcccttcgc
     6421 tctgtcagcc cctcttacta ttcctgatat cagacagcat gcagaaacat tgtgcgcatg
     6481 ttgactcaga tgctcctcag tgacttgaat tctttcagct gtgttactct attagatggg
     6541 tcatcagaag gctgtcagag ataagaacag ggaagacaga gatggacatg agcagagagg
     6601 aggaaaaatg gctcccttac tggtgtcggg aatcttccac atagaggtca tggtctaaga
     6661 atctaaactt tttacctgta gatttaaaac attgcctttc tcatacattc ctcatcctcg
     6721 tttccccaaa agactcttgt cagggtttat gaggccgacc agattaaata cccatattca
     6781 gtttctcttg attttcttaa gaagtatttt aattcccttg tgtatttggt gttcactact
     6841 gttcttgtga ctcaagtctc agagagaaac tgcggtcagc cacctcggtc ctcctgttgc
     6901 acgtgggtgg cggcatccgt gtgtaccgat gcagttacgg caccttgtga aaaggagtgt
     6961 gagcggtgtc tatccgagga taggaaactt cagtctgcac ttctgtgagc cagaagaata
     7021 caaagctgtc acatttccag cagtttagtt ttcattctta gctctttttg aaaaatctta
     7081 aaatacttta acattcctta agtagtgtca aatctagggt agaaggcttt tttcccccca
     7141 tcctaaaaag ggctccatct ttttcatctt tttgttactc ttagaaattt atgctcagta
     7201 cattttaata gtttctggtc tctagactat gtcagcattg gagtggttgg ttgtgaatat
     7261 caagctacta ctgtttttct ttggagacat gaactttctg tttggggcat agaaggtctg
     7321 gtttaagcaa catgtgaaag atcacctaaa ccaaagcccg ctcgctgtaa gggcagttgc
     7381 ctcctgttgg ttcaccttca ccttgaacga caggaacact tcagtgcgca gtgagtgttg
     7441 tctgtaacgt ctctacctgg gctttcagtc gcgtgttgct cttcgcattt cctaaagttc
     7501 ctgatgctat gattctggtt tttgtggtgt tttgctgctt gtgtgtgatt gattattggt
     7561 ttgtttgttt gaactaagtg ggactataaa tgtagataga tgtgttttag taccaagatg
     7621 ttcttttttc attatcagtc tttcagatgt ctattttctt gctgaatagc agaggacttt
     7681 atttccacct ccctataaag tgtgagcact gtgtttcagc gagctgcatt gcgtactttt
     7741 gctgaaaact tctctgtaaa cacaattgcc ttgttgagtt tcattgtaaa ctgactcgcc
     7801 atgcgatgca ctgttgatag cttcctgatg tgtggtggat aagagtgata aaataaagct
     7861 tacaaagaaa ag
//
