LOCUS       NM_009467               1901 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus UDP glucuronosyltransferase 2 family, polypeptide B5
            (Ugt2b5), mRNA.
ACCESSION   NM_009467
VERSION     NM_009467.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1901)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
REFERENCE   2  (bases 1 to 1901)
  AUTHORS   Burchell,B., Nebert,D.W., Nelson,D.R., Bock,K.W., Iyanagi,T.,
            Jansen,P.L., Lancet,D., Mulder,G.J., Chowdhury,J.R., Siest,G. et
            al.
  TITLE     The UDP glucuronosyltransferase gene superfamily: suggested
            nomenclature based on evolutionary divergence
  JOURNAL   DNA Cell Biol 10 (7), 487-494 (1991)
   PUBMED   1909870
  REMARK    Review article
REFERENCE   3  (bases 1 to 1901)
  AUTHORS   Kimura,T. and Owens,I.S.
  TITLE     Mouse UDP glucuronosyltransferase. cDNA and complete amino acid
            sequence and regulation
  JOURNAL   Eur J Biochem 168 (3), 515-521 (1987)
   PUBMED   3117546
REFERENCE   4  (bases 1 to 1901)
  AUTHORS   Krasnewich,D., Kozak,C.A., Nebert,D.W. and Mackenzie,P.I.
  TITLE     Localization of UDP glucuronosyltransferase gene(s) on mouse
            chromosome 5
  JOURNAL   Somat Cell Mol Genet 13 (2), 179-182 (1987)
   PUBMED   3105095
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK136480.1 and AI118071.1.
            
            On Sep 10, 2010 this sequence version replaced NM_009467.2.
            
            Sequence Note: An in-frame AUG is located 11 codons upstream of the
            annotated translation start site but is not being annotated as a
            start site since it is not conserved and is in a weak Kozak
            sequence context.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK136480.1, X06358.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849386, SAMN00849389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on single protein-coding
                                                transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1884              AK136480.1         2-1885
            1885-1901           AI118071.1         1-17                c
FEATURES             Location/Qualifiers
     source          1..1901
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 43.56 cM"
     gene            1..1901
                     /gene="Ugt2b5"
                     /gene_synonym="M-1; Udpgt-3; Udpgt2b5; Ugt2b17"
                     /note="UDP glucuronosyltransferase 2 family, polypeptide
                     B5"
                     /db_xref="GeneID:22238"
                     /db_xref="MGI:MGI:98900"
     exon            1..758
                     /gene="Ugt2b5"
                     /gene_synonym="M-1; Udpgt-3; Udpgt2b5; Ugt2b17"
                     /inference="alignment:Splign:2.1.0"
     CDS             35..1627
                     /gene="Ugt2b5"
                     /gene_synonym="M-1; Udpgt-3; Udpgt2b5; Ugt2b17"
                     /EC_number="2.4.1.17"
                     /note="UDP-glucuronosyltransferase 2 family, member 5;
                     UDP-glucuronosyltransferase 2B5;
                     UDP-glucuronosyltransferase 2B17"
                     /codon_start=1
                     /product="UDP-glucuronosyltransferase 2B17 precursor"
                     /protein_id="NP_033493.3"
                     /db_xref="CCDS:CCDS19385.3"
                     /db_xref="GeneID:22238"
                     /db_xref="MGI:MGI:98900"
                     /translation="MPGKWISALLLLQISCCFRSVKCGKVLVWPMEFSHWMNIKIILD
                     ELVQRGHEVTVLRPSAYYVLDPKKSPGLKFETFPTSVSKDNLENFFIKFVDVWTYEMP
                     RDTCLSYSPLLQNMIDEFSDYFLSLCKDVVSNKELMTKLQESKFDVLLSDPVASCGEL
                     IAELLQIPFLYSIRFSPGYQIEKSSGRFLLPPSYVPVILSGLGGQMTFIERIKNMICM
                     LYFDFWFQMFNDKKWDSFYSEYLGRPTTLVETMGQAEMWLIRSNWDLEFPHPTLPNVD
                     YVGGLHCKPAKPLPKDMEEFVQSSGDHGVVVFSLGSMVSNMTEEKANAIAWALAQIPQ
                     KVLWKFDGKTPATLGHNTRVYKWLPQNDLLGHPKTKAFVTHGGANGVYEAIYHGIPMI
                     GIPLFGEQHDNIAHMVAKGAAVALNIRTMSKSDVLNALEEVIENPFYKKNAMWLSTIH
                     HDQPMKPLDRAVFWIEFVMRHKRAKHLRPLGHNLTWYQYHSLDVIGFLLSCVATTIVL
                     SVKCLLFIYRFFVKKENKMKNE"
     exon            759..907
                     /gene="Ugt2b5"
                     /gene_synonym="M-1; Udpgt-3; Udpgt2b5; Ugt2b17"
                     /inference="alignment:Splign:2.1.0"
     exon            908..1039
                     /gene="Ugt2b5"
                     /gene_synonym="M-1; Udpgt-3; Udpgt2b5; Ugt2b17"
                     /inference="alignment:Splign:2.1.0"
     exon            1040..1127
                     /gene="Ugt2b5"
                     /gene_synonym="M-1; Udpgt-3; Udpgt2b5; Ugt2b17"
                     /inference="alignment:Splign:2.1.0"
     exon            1128..1347
                     /gene="Ugt2b5"
                     /gene_synonym="M-1; Udpgt-3; Udpgt2b5; Ugt2b17"
                     /inference="alignment:Splign:2.1.0"
     exon            1348..1894
                     /gene="Ugt2b5"
                     /gene_synonym="M-1; Udpgt-3; Udpgt2b5; Ugt2b17"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1612..1617
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ugt2b5"
                     /gene_synonym="M-1; Udpgt-3; Udpgt2b5; Ugt2b17"
                     /note="hexamer: AATGAA"
     regulatory      1639..1644
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ugt2b5"
                     /gene_synonym="M-1; Udpgt-3; Udpgt2b5; Ugt2b17"
                     /note="hexamer: AATGAA"
     polyA_site      1653
                     /gene="Ugt2b5"
                     /gene_synonym="M-1; Udpgt-3; Udpgt2b5; Ugt2b17"
                     /note="major polyA site"
     polyA_site      1657
                     /gene="Ugt2b5"
                     /gene_synonym="M-1; Udpgt-3; Udpgt2b5; Ugt2b17"
                     /note="major polyA site"
     regulatory      1860..1865
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ugt2b5"
                     /gene_synonym="M-1; Udpgt-3; Udpgt2b5; Ugt2b17"
                     /note="hexamer: AATAAA"
     polyA_site      1894
                     /gene="Ugt2b5"
                     /gene_synonym="M-1; Udpgt-3; Udpgt2b5; Ugt2b17"
                     /note="major polyA site"
ORIGIN      
        1 aatggactgt gagagaagga ttttgatttt caagatgcct ggaaagtgga tttctgctct
       61 gctgctgctg cagataagtt gctgcttcag atctgtgaaa tgtgggaaag tgttggtgtg
      121 gccgatggaa ttcagtcatt ggatgaacat aaaaataata ctggatgaac tggtacagag
      181 aggccatgaa gtcactgttc tgagaccttc agcttactat gttcttgatc ccaaaaaatc
      241 acctggcctt aagtttgaaa cttttcctac atctgtcagt aaagacaatc tggaaaattt
      301 tttcattaag tttgtggatg tgtggactta tgaaatgcca agggatacat gtttgtcata
      361 ttctccttta ctgcaaaata tgattgatga attttctgat tattttctaa gtctttgtaa
      421 agatgttgtt tcaaacaaag agctcatgac aaagctacag gaatccaagt ttgatgtcct
      481 tttgtcagat cctgttgctt cctgtgggga gctcatagct gaactgctcc agattccttt
      541 tctgtacagt atccgcttct ctccaggcta ccaaattgaa aagtccagcg ggagatttct
      601 actccctccc tcttatgtac ctgtaattct gtcaggatta ggtggacaaa tgacattcat
      661 agagaggata aaaaatatga tatgcatgct ttattttgac ttttggttcc agatgtttaa
      721 tgataagaaa tgggactcat tttacagtga gtatttggga aggccaacca ccttagttga
      781 gacaatgggc caagcagaaa tgtggctcat tagatccaac tgggatttgg agtttcctca
      841 cccaacctta ccaaatgttg actatgttgg aggactccat tgcaaacctg ctaaaccctt
      901 gcctaaggat atggaagaat ttgtccagag ctctggagac catggtgtgg tggtcttttc
      961 tcttgggtca atggttagta acatgacaga agaaaaagcc aacgcaattg catgggccct
     1021 tgcccagatt ccacaaaagg ttctttggaa atttgatggc aaaaccccag caactttagg
     1081 acacaatacc agagtgtaca agtggctccc ccagaatgac ctccttggtc atccaaaaac
     1141 caaagccttt gtaactcatg gtggggccaa tggtgtctac gaggcgatct atcatggaat
     1201 ccctatgatt ggcattcctt tgtttggaga acagcatgat aacattgccc atatggtggc
     1261 caaaggagca gctgttgcat tgaatatcag aacaatgtca aagtcagatg tgctcaatgc
     1321 actggaggag gtcatagaaa atcctttcta taaaaagaat gctatgtggt tgtcaaccat
     1381 tcaccatgac cagcctatga aacccctgga cagggctgtc ttctggattg agtttgttat
     1441 gcgccacaaa agagccaagc acctgagacc acttggacat aaccttacct ggtaccagta
     1501 ccactctctg gatgtgattg gattcctact ctcttgtgtg gcaaccacta tagtccttag
     1561 tgtaaagtgc ctcttgttca tttaccgatt ctttgtaaag aaagaaaata aaatgaagaa
     1621 tgagtagagc tcactgacaa tgaactacat gaacaaactt tcagcctcat tcttatttat
     1681 gaaccacctt ctaaacactt gacttgattc ttttctaata aaggcacatc ttctttgtaa
     1741 atttttacca tataagaaga catatacatc tgtgaatact gatacattct caaaaatctc
     1801 catttctgta atttttaaac tatttaatgt aaaaaattat attgtagaaa aatgtgggaa
     1861 ataaaatgtt cttgatagag tcttaaaaat caaaaaaaaa a
//
