LOCUS       NM_001029867            1888 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus UDP glucuronosyltransferase 2 family, polypeptide B36
            (Ugt2b36), mRNA.
ACCESSION   NM_001029867 XM_132178
VERSION     NM_001029867.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1888)
  AUTHORS   Chen M, Guo L, Dong D, Yu F, Zhang T and Wu B.
  TITLE     The nuclear receptor Shp regulates morphine withdrawal syndrome via
            modulation of Ugt2b expression in mice
  JOURNAL   Biochem Pharmacol 161, 163-172 (2019)
   PUBMED   30689982
  REMARK    GeneRIF: Shp regulated morphine withdrawal syndrome via modulation
            of Ugt2b expression.
REFERENCE   2  (bases 1 to 1888)
  AUTHORS   Kurita A, Miyauchi Y, Ikushiro S, Mackenzie PI, Yamada H and Ishii
            Y.
  TITLE     Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase
            (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36
            as the Predominant Isoform Involved in Morphine Glucuronidation
  JOURNAL   J Pharmacol Exp Ther 361 (2), 199-208 (2017)
   PUBMED   28228532
  REMARK    GeneRIF: As Ugt2b36 is highly expressed in the liver, it is most
            likely that Ugt2b36 is a major morphine Ugt in mouse liver.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC100269.7 and
            AC119816.5.
            
            On Jul 27, 2005 this sequence version replaced XM_132178.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK149425.1, BC141232.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-755               AC100269.7         218724-219478
            756-904             AC100269.7         220293-220441
            905-1036            AC100269.7         221730-221861
            1037-1124           AC100269.7         229682-229769
            1125-1344           AC100269.7         230190-230409
            1345-1888           AC119816.5         11544-12087
FEATURES             Location/Qualifiers
     source          1..1888
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 43.56 cM"
     gene            1..1888
                     /gene="Ugt2b36"
                     /note="UDP glucuronosyltransferase 2 family, polypeptide
                     B36"
                     /db_xref="GeneID:231396"
                     /db_xref="MGI:MGI:3576103"
     exon            1..755
                     /gene="Ugt2b36"
                     /inference="alignment:Splign:2.1.0"
     CDS             32..1624
                     /gene="Ugt2b36"
                     /EC_number="2.4.1.17"
                     /codon_start=1
                     /product="UDP glucuronosyltransferase 2 family,
                     polypeptide B36 precursor"
                     /protein_id="NP_001025038.1"
                     /db_xref="CCDS:CCDS19384.1"
                     /db_xref="GeneID:231396"
                     /db_xref="MGI:MGI:3576103"
                     /translation="MLWKWISALLLLQISCCFRSAKCGKVLVWPVDYSHWMNIKIILD
                     ELKQKGHEVTVLRPSTSIFLDPKKSPGLKFETFPTSFSNDVMEIIFAKAVERWTYEVP
                     RDTCLSYSPLLQNIFDEYSDYCLTLCKDTVSNKQLMAKLQESKFDVILSDAIGPCGEL
                     IAELLQIPFLYSLRFSPGYYLEKYSGGLPLPPSYVPVILSGLSGQMTFKERVKNMICM
                     LYFDFWFQTFREKKWDQFYSETLGRPTTLIETMGKAEMWLIRSYWDLEFPHPTLPNVY
                     YVGGVHCKPAKPLPKEMEDFVQSSGEHGVVVFSLGSMVSNMTEEKANAIAWALAQIPQ
                     KVLWRFDGKTPATLGPNTRIYKWLPQNDLLGHPKTKAFITHGGANGLYEAIHHGIPMI
                     GIPLFGEQHDNIAHMVAKGAAVTLNIRTMSRSDLLNALEEVIDNPFYKENAMWLSTIH
                     HDQPMKPLDRAVFWIEFVMRHKGAKHLRPLAYNLTWYQYHSLDVIGFLLAFVTFIVAL
                     IVKCFLFVYRFFVKKEKKMKNE"
     exon            756..904
                     /gene="Ugt2b36"
                     /inference="alignment:Splign:2.1.0"
     exon            905..1036
                     /gene="Ugt2b36"
                     /inference="alignment:Splign:2.1.0"
     exon            1037..1124
                     /gene="Ugt2b36"
                     /inference="alignment:Splign:2.1.0"
     exon            1125..1344
                     /gene="Ugt2b36"
                     /inference="alignment:Splign:2.1.0"
     exon            1345..1888
                     /gene="Ugt2b36"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cactctgaag agaagaacat tgattttcag aatgctttgg aagtggattt ctgctctgct
       61 gctgctgcag ataagttgct gcttcagatc tgcaaagtgt gggaaggtgt tggtatggcc
      121 ggtggactac agtcactgga tgaatataaa gataatactg gatgaactta aacagaaggg
      181 ccatgaagtc actgttttga gaccttcaac ttccattttt cttgatccca aaaaatcgcc
      241 tggccttaag tttgaaactt ttcctacatc tttcagtaat gatgtcatgg aaattatttt
      301 tgcaaaggct gtggaaagat ggacttatga ggttccaaga gatacatgtt tatcatattc
      361 tcctttatta caaaatatat ttgatgaata ttctgattac tgtttaactc tttgcaaaga
      421 cacagtttca aacaaacagc tcatggcaaa actccaggaa tccaagtttg atgtcatttt
      481 gtcagatgct attggtccct gtggggagct catagctgaa ctgctccaaa ttccttttct
      541 atatagtctt cgcttctctc ctggctacta tcttgaaaaa tacagtggag gactccctct
      601 ccctccctct tatgtacctg taattttgtc aggattaagt ggtcaaatga cattcaaaga
      661 gagggtaaag aatatgatat gtatgcttta ttttgacttt tggttccaga catttaggga
      721 gaagaaatgg gatcagtttt acagcgaaac tttgggaagg ccaaccacct taattgagac
      781 aatgggcaaa gcagaaatgt ggctcattag atcctattgg gatttggagt ttcctcaccc
      841 aaccttacca aatgtttact atgttggagg agtccattgc aaacctgcta aaccattgcc
      901 taaggaaatg gaagactttg ttcagagctc tggagagcat ggtgtggtgg tgttttctct
      961 ggggtcaatg gtcagtaata tgacagaaga aaaggccaat gcaattgcat gggctcttgc
     1021 ccagattcca caaaaggttc tttggagatt tgacggcaaa actccagcca ccttaggacc
     1081 caataccaga atctacaagt ggcttcccca aaatgatctt cttggtcatc caaaaaccaa
     1141 agcctttata actcatggtg gcgcgaatgg actctacgag gcgatccatc atggaatccc
     1201 tatgattggc attcctttgt ttggagaaca acatgataac attgctcaca tggtggccaa
     1261 aggagcagct gttacattga atatcagaac gatgtcaagg tcagatttgc tcaatgcact
     1321 ggaggaagtc atagacaatc ctttctataa agagaatgct atgtggttgt caaccattca
     1381 ccatgaccag cctatgaagc ccctggacag agcagtcttc tggattgagt ttgtcatgcg
     1441 ccacaaaggg gccaagcatc tgagaccact tgcatacaac ctcacctggt accagtacca
     1501 ctctctggat gtgattggat tcctgcttgc ttttgtgaca ttcattgtag ccctcattgt
     1561 aaagtgcttc ttgtttgttt accgattctt tgtaaagaaa gaaaagaaaa tgaagaatga
     1621 gtagaactca ttgataatgc attacatgaa taaaatttta ccatcattct atgttatgaa
     1681 ctatctttta aacactcact tatcacttta cagaagcata tcttttttgg agttttataa
     1741 catgtgaaaa caaaacacat ataattctgg ggctactgat atgttatcaa agaatcctat
     1801 catttatttt aattgtcaaa ctattaaatg taaaataatt tgcatgtata gaaacatatg
     1861 aaaaataaaa atttacttga tagagcct
//
