LOCUS       NM_152811               2560 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus UDP glucuronosyltransferase 2 family, polypeptide B1
            (Ugt2b1), mRNA.
ACCESSION   NM_152811
VERSION     NM_152811.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2560)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2560)
  AUTHORS   Miyauchi,Y., Kurita,A., Yamashita,R., Takamatsu,T., Ikushiro,S.,
            Mackenzie,P.I., Tanaka,Y. and Ishii,Y.
  TITLE     Hetero-oligomer formation of mouse UDP-glucuronosyltransferase
            (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity
            towards morphine, an activity which is absent in homo-oligomers of
            either UGT
  JOURNAL   Biochem Biophys Res Commun 525 (2), 348-353 (2020)
   PUBMED   32093886
  REMARK    GeneRIF: Hetero-oligomer formation of mouse
            UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain
            of glucuronidation activity towards morphine, an activity which is
            absent in homo-oligomers of either UGT.
REFERENCE   3  (bases 1 to 2560)
  AUTHORS   Yabusaki,R., Iwano,H., Tsushima,S., Koike,N., Ohtani,N.,
            Tanemura,K., Inoue,H. and Yokota,H.
  TITLE     Weak activity of UDP-glucuronosyltransferase toward Bisphenol
            analogs in mouse perinatal development
  JOURNAL   J Vet Med Sci 77 (11), 1479-1484 (2015)
   PUBMED   26074487
  REMARK    GeneRIF: The metabolism of bisphenols by UGT2B1 in fetal, newborn,
            and maternal mice is reported.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC027200.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC027200.1, AK004971.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849386 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2560
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="FVB/N"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 43.56 cM"
     gene            1..2560
                     /gene="Ugt2b1"
                     /gene_synonym="1300012D20Rik"
                     /note="UDP glucuronosyltransferase 2 family, polypeptide
                     B1"
                     /db_xref="GeneID:71773"
                     /db_xref="MGI:MGI:1919023"
     exon            1..729
                     /gene="Ugt2b1"
                     /gene_synonym="1300012D20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            730..878
                     /gene="Ugt2b1"
                     /gene_synonym="1300012D20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            879..1010
                     /gene="Ugt2b1"
                     /gene_synonym="1300012D20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1011..1098
                     /gene="Ugt2b1"
                     /gene_synonym="1300012D20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1099..1318
                     /gene="Ugt2b1"
                     /gene_synonym="1300012D20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1319..2545
                     /gene="Ugt2b1"
                     /gene_synonym="1300012D20Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2527..2532
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ugt2b1"
                     /gene_synonym="1300012D20Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2545
                     /gene="Ugt2b1"
                     /gene_synonym="1300012D20Rik"
                     /note="major polyA site"
ORIGIN      
        1 gcaagatgtc tatgaaacag gcttcagttt ttctgttgat acagttcata tgctatatta
       61 gacctggagc ctgtgggaaa gtgctggtgt ggcctacaga atacagccat tggataaata
      121 tgaaaataat cctggatgaa cttgtccaga gaggtcatga cgtcaccgtt ctcatatctt
      181 ctgcttccat cctcattggg ccgagcaatg aatcttctat taattttgaa atttattctg
      241 cacctttgag taaagatgat cttgaatatg cttttgaaaa atgggtagga aactggacat
      301 acgaattaaa aaaacttcca ttttggacat cttattcaaa actgcaaaaa atctccagtg
      361 aatattcaga catgattgaa agtttctgca aagcagtagt ttggaacaag agcctcatga
      421 aaaaactcca aggatctaag tttgatgtcg ttctagcaga tgccttggtt ccctgtggtg
      481 agctgctatc agaactgctt aagacacctt tagtatacag tctccgcttc tgtcctggat
      541 acaaatgtga aaagtacagt gggggccttc cactcccccc ttcctatgtg cctgtggttc
      601 tgtcagaact aagtgaccac atgacatttg cagaaagggt gaagaatatg ttgcaggtgt
      661 tgctttttga cttttggttt caaacattta acgagaaatc ctggaatcag ttttacagtg
      721 atgttctagg gagacctaca acattaactg agatgatggg gaaggcagac atatggctcg
      781 ttcgaacctt ctgggacttg aaatttcctc accctttctt gcctaatttt gactttgttg
      841 gaggactcca ttgtaaacca gccaaaccac tgcctaagga aatggaagaa tttgttcaga
      901 gctctggaga acatggtgtg gtggtgtttt ctctgggatc aatggttaaa aacattaaag
      961 aagaaaaggc caatgtagtt gcttctgctc ttgcccagat tccacagaag gttctgtgga
     1021 gatttgatgg taagaaacca gacaccttag gatccaacac tcggctctac aagtggatcc
     1081 cccagaatga ccttcttggt catccaaaaa ccaaagcttt tatagctcat ggtggaacca
     1141 atggcatcta tgaggcgatc taccatggca ttcctattgt tggtattccc ttgtttgggg
     1201 atcaacctga taatattaac cacatagtag ccaagggagc agctgttaga gtggactttg
     1261 atacaatgtc aactacagac cttctcactg ccttgaagac tgtcattaat gacccttcct
     1321 ataaagagaa tgccatgaga ttatccagaa tccaccatga ccagccaatg aagcccttgg
     1381 accgagctgt cttctggatc gagtatgtca tgcgcaacaa gggagccaag caccttcgcc
     1441 cagctctgca tgaccttacc tggttccagt accactctct ggatgtgatt gggttcctat
     1501 tggtctgtgt ggtagctgtg gtattcatca ttgcaaaatg ttgcctcttt tgttgccata
     1561 agactgctaa catgggaaag aagaaaaaag agtagcttca tgaaggctga agcagagagt
     1621 cctgagagat gagcctctgc cagctgcttc cagcagaaac ctgttgtctg tcccaggtgc
     1681 cttccctctg aaacaagaca gggtcaggac ttcattaaag atagctctca tagatgcact
     1741 atatgttgaa tgcacgtaag gatttatgca agctatacac tcagagctct agaagcaaaa
     1801 ttgtgtgttc agtttagaat gttttaatgt aaatgaggaa ctatacccaa caacaatcac
     1861 tgaggttact gtagttcaca aaatttgcat aggcataaag cctttgaaaa acctctctaa
     1921 atattagtta attttttatg ctctgtcttc atttaatgaa cttatttttc ttcccttcct
     1981 tttttcttct ctttcatttt tttttgtatt gctcataaat aatagcgttc aggtacagaa
     2041 catttgaaat agactcactt ttccatcaat ataaggaaag ccattgtttc tggttattaa
     2101 ttgggtacag caaacttcca acaaatattt cctaaagggc ctgtggtgga ggctactctc
     2161 cttcaatcag aagccttttt cagacactaa tcttcaagca tttactctta ctgctcctga
     2221 cataaattcc agtacttggg agttcttagg cttggcaaga ttattgattt attttccttc
     2281 ttatctctta ctcacaactg acctgaacac tgtcattctc attctgcctt ttgaagtaga
     2341 tttaagctgc caaatgtccc attctctctc gctttgaaag tacacatcca agagaagatt
     2401 atctttttaa gtcataccat cacctagctc atgttatatt tcgtatctga aatatccccc
     2461 acagacacac aatgtacttt gctgattttg tttaactcat tcatacagaa tttcttacct
     2521 tgattcaata aaatgttaaa atcttaaaaa aaaaaaaaaa
//
