LOCUS       NM_028094               2254 bp    mRNA    linear   ROD 14-FEB-2025
DEFINITION  Mus musculus UDP glucuronosyltransferase 2 family, polypeptide A3
            (Ugt2a3), mRNA.
ACCESSION   NM_028094
VERSION     NM_028094.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2254)
  AUTHORS   Chen,S., Lu,W., Yueh,M.F., Rettenmeier,E., Liu,M., Paszek,M.,
            Auwerx,J., Yu,R.T., Evans,R.M., Wang,K., Karin,M. and Tukey,R.H.
  TITLE     Intestinal NCoR1, a regulator of epithelial cell maturation,
            controls neonatal hyperbilirubinemia
  JOURNAL   Proc Natl Acad Sci U S A 114 (8), E1432-E1440 (2017)
   PUBMED   28167773
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2017 May 16;114(20):E4115. doi:
            10.1073/pnas.1705671114.. Paszek, Miles [added]. PMID: 28484028]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC101835.7.
            
            On Sep 30, 2022 this sequence version replaced NM_028094.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK050327.1, BC025795.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849378, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-753               AC101835.7         39328-40080         c
            754-902             AC101835.7         34103-34251         c
            903-1034            AC101835.7         32422-32553         c
            1035-1122           AC101835.7         30567-30654         c
            1123-1342           AC101835.7         29959-30178         c
            1343-2254           AC101835.7         27720-28631         c
FEATURES             Location/Qualifiers
     source          1..2254
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 43.56 cM"
     gene            1..2254
                     /gene="Ugt2a3"
                     /gene_synonym="2010321J07Rik"
                     /note="UDP glucuronosyltransferase 2 family, polypeptide
                     A3"
                     /db_xref="GeneID:72094"
                     /db_xref="MGI:MGI:1919344"
     exon            1..753
                     /gene="Ugt2a3"
                     /gene_synonym="2010321J07Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             33..1637
                     /gene="Ugt2a3"
                     /gene_synonym="2010321J07Rik"
                     /EC_number="2.4.1.17"
                     /note="UDP-glucuronosyltransferase 2A3; UDPGT 2A3"
                     /codon_start=1
                     /product="UDP-glucuronosyltransferase 2A3 precursor"
                     /protein_id="NP_082370.2"
                     /db_xref="CCDS:CCDS19387.1"
                     /db_xref="GeneID:72094"
                     /db_xref="MGI:MGI:1919344"
                     /translation="MVSEKCVAAFFLLQLCWAGCGFCSKVLVWPCDMSHWLNLKTILE
                     ELGARGHEVTVLKYPSIIIDQSKRIPLHFENIPLLYEIETAENRLNEIANLAVNVIPN
                     LSLWEAAKTLQDFFLQVTGDFESICRSVLYNQKFMDKLRDAQYDVVVIDPVVPCGELV
                     AEVLQIPFVYTLRFSMGYYMEKHCGQLPIPLSYVPVVMSELTDNMTFTERVKNMMFSL
                     LFEYWLQQYDFAFWDQFYSETLGRPTTFCKTVGKADIWLIRTYWDVEFPRPYLPNFEF
                     VGGLHCKPAKPLPKEMEEFVQSSGEHGVVVFSLGSMVKNLTEEKANLIASVLAQIPQK
                     VLWRYSGKKPATLGSNTRLFNWIPQNDLLGHPKTKAFITHGGTNGIYEAIYHGVPMVG
                     VPMLGDQPHNIAHMEAKGAALKVSISTMTSTDLLSAVRAVINEPSYKENAMRLSRIHH
                     DQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLLCVVTLTFII
                     TKFCLFVCQKLYMKESKKMGNRKKKN"
     exon            754..902
                     /gene="Ugt2a3"
                     /gene_synonym="2010321J07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            903..1034
                     /gene="Ugt2a3"
                     /gene_synonym="2010321J07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1035..1122
                     /gene="Ugt2a3"
                     /gene_synonym="2010321J07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1123..1342
                     /gene="Ugt2a3"
                     /gene_synonym="2010321J07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1343..2254
                     /gene="Ugt2a3"
                     /gene_synonym="2010321J07Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1755..1760
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ugt2a3"
                     /gene_synonym="2010321J07Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1781
                     /gene="Ugt2a3"
                     /gene_synonym="2010321J07Rik"
                     /note="major polyA site"
     regulatory      2101..2106
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ugt2a3"
                     /gene_synonym="2010321J07Rik"
                     /note="hexamer: AATAAT"
     polyA_site      2119
                     /gene="Ugt2a3"
                     /gene_synonym="2010321J07Rik"
     regulatory      2233..2238
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ugt2a3"
                     /gene_synonym="2010321J07Rik"
                     /note="hexamer: AATATA"
     polyA_site      2254
                     /gene="Ugt2a3"
                     /gene_synonym="2010321J07Rik"
ORIGIN      
        1 aatctttgcg aaacaacttg aggaggcaca atatggtctc tgaaaaatgt gttgcggcat
       61 tttttctgct gcagctttgc tgggccggct gtggattctg cagcaaggtc ctcgtgtggc
      121 cctgtgatat gagccactgg ctgaatctaa agactattct tgaggagctt ggagcaagag
      181 ggcacgaggt aacagtcctg aaatacccca gtatcatcat agatcagagt aaacgtattc
      241 cactgcactt tgagaatatt cctttgctgt atgaaatcga gacagctgag aatcgtttaa
      301 atgagattgc aaatctagct gtgaatgtca ttccaaacct gtcactgtgg gaagcagcaa
      361 aaacattaca agacttcttt cttcaagtaa ctggagattt tgaaagtatt tgtaggagtg
      421 tattgtacaa ccagaaattc atggacaagc tacgggatgc acaatatgat gtagtggtta
      481 tagaccctgt cgttccctgt ggagagttgg tggcagaagt gcttcagatc cctttcgtat
      541 acacactgag gttcagcatg ggctactaca tggagaaaca ctgtggccag cttccaattc
      601 cactctcgta tgtaccggtt gtcatgagtg agctgacaga caatatgacc ttcacagaga
      661 gggtgaaaaa tatgatgttt tcactgttgt ttgagtactg gctccagcaa tatgactttg
      721 cattctggga tcagttttac agtgaaaccc taggaaggcc cacaacgttc tgtaagactg
      781 tggggaaagc tgacatttgg ctaatccgaa catattggga tgttgagttt cctcgtccat
      841 atttaccaaa ttttgagttt gtgggaggac tgcactgcaa acctgccaag cctttaccta
      901 aggaaatgga agaatttgtt cagagctctg gagaacatgg tgtagtagta ttttcactgg
      961 ggtcaatggt caaaaacctg acagaagaga aagccaacct cattgcctct gtccttgccc
     1021 agattcccca gaaggttttg tggagatact caggcaagaa gccagccaca ttaggatcca
     1081 atactcggct ttttaattgg attccccaga atgatcttct tggacatcct aaaaccaaag
     1141 ctttcatcac acatggtgga acaaacggga tttatgaagc catttaccat ggggtcccta
     1201 tggtgggcgt tcccatgtta ggggatcagc ctcacaacat cgctcacatg gaggccaagg
     1261 gagcagccct gaaagtcagc atcagtacaa tgacgagcac agatttactc agtgctgtga
     1321 gggcagtcat taatgagcct tcttataaag agaatgccat gcggttatca agaatccacc
     1381 atgatcagcc agtgaagccc ctggaccgag cagtcttctg gattgagttt gtcatgcgtc
     1441 acaaaggagc caagcatctt cgtgtggcag cccatgacct cagctggttt cagtaccact
     1501 ccctagatgt gattgggttc ctattgttgt gtgtcgttac tctgacattc atcatcacta
     1561 aattttgttt gtttgtgtgt caaaaacttt atatgaaaga aagtaagaaa atggggaaca
     1621 gaaagaaaaa gaactaggtc ttttttaggt ttgggaaagc cctgagtgac aattatatta
     1681 acaatcacca caagaagcat gcaacttcct gctttatacc tattttcaaa taagcagctc
     1741 tgtttcagac tggaaataaa tgtaaacatt aagcatgata attaactact gatttgttcc
     1801 aatcttctat cttgtaggca ttctcctctc actcttctaa gatatggaaa attaattcta
     1861 aatatattct atagaaagga agtgatgaat aacaatatgc tagacctctg ggaagacata
     1921 taataccaat cttattgatg tatatgagga tctcttacag tcaatgtcat aagcctatca
     1981 tattgtctaa gaacaaccaa aagaatttag tgtgagaggg tacttttcta ataagaagga
     2041 acgtttctgt ttttatagtg ttgcagatat tagagcatga tttctttttt attttccaaa
     2101 aataatttat tgaaaagaat ttttgtgcaa tgtattttgg tcattttccc ccttccctaa
     2161 ttcctttaag atcctaccaa tcccactgcc cacttaaata catctttctc tctcaaatag
     2221 ttaaagtaga aaaatatacc aaacaaaaaa agac
//
