LOCUS       NM_053184               2597 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus UDP glucuronosyltransferase 2 family, polypeptide A1
            (Ugt2a1), mRNA.
ACCESSION   NM_053184
VERSION     NM_053184.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2597)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2597)
  AUTHORS   Heydel,J., Leclerc,S., Bernard,P., Pelczar,H., Gradinaru,D.,
            Magdalou,J., Minn,A., Artur,Y. and Goudonnet,H.
  TITLE     Rat olfactory bulb and epithelium UDP-glucuronosyltransferase 2A1
            (UGT2A1) expression: in situ mRNA localization and quantitative
            analysis
  JOURNAL   Brain Res Mol Brain Res 90 (1), 83-92 (2001)
   PUBMED   11376859
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK140757.1 and BC048926.1.
            
            On Oct 31, 2007 this sequence version replaced NM_053184.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC048926.1, AK140757.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1953              AK140757.1         2-1954
            1954-2597           BC048926.1         1942-2585
FEATURES             Location/Qualifiers
     source          1..2597
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 43.56 cM"
     gene            1..2597
                     /gene="Ugt2a1"
                     /note="UDP glucuronosyltransferase 2 family, polypeptide
                     A1"
                     /db_xref="GeneID:94215"
                     /db_xref="MGI:MGI:2149905"
     exon            1..30
                     /gene="Ugt2a1"
                     /inference="alignment:Splign:2.1.0"
     exon            31..799
                     /gene="Ugt2a1"
                     /inference="alignment:Splign:2.1.0"
     CDS             82..1668
                     /gene="Ugt2a1"
                     /EC_number="2.4.1.17"
                     /note="UDP glycosyltransferase 2 family, polypeptide A1;
                     UDP-glucuronosyltransferase 2A1; UDPGT 2A1; olfactory UDP
                     glucuronosyltransferase"
                     /codon_start=1
                     /product="UDP-glucuronosyltransferase 2A1 precursor"
                     /protein_id="NP_444414.2"
                     /db_xref="CCDS:CCDS39129.1"
                     /db_xref="GeneID:94215"
                     /db_xref="MGI:MGI:2149905"
                     /translation="MLKNILLCSLQISLLGMSLGGNVLIWPMEGSHWLNVKIIIDELL
                     RKEHNVTVLVASGALFITPSSISPSLTFEIYPVPFGKEKIESVIKDFVLTWLENRPSP
                     STIWTFYKEMAKVIEEFHLVSRGICDGVLKNEKLMSKLQKEKFEVLLSDPVFPCGDIV
                     ALKLGIPFIYSLRFSPASTVEKHCGKVPFPPSYVPAILSELTDQMSFTDRVRNFISYR
                     MQDYMFETLWKQWDSYYTKALGRPTTLCETMGKAEIWLMRTYWDFEFPRPYLPNFEFV
                     GGLHCKPAKPLPKEMEEFVQTSGEHGIVVFSLGSMVKNLTDEKANLIASALAQIPQKV
                     LWRYKGKIPDTLGSNTRLFDWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPMVGV
                     PMFADQPDNIAHMKAKGAAVEVNMNTMTSSDLLNALRTVINEPSYKENAMRLSRIHHD
                     QPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLACVASAILLVA
                     KCCLFIFQKVGKTGKKKKRD"
     exon            800..948
                     /gene="Ugt2a1"
                     /inference="alignment:Splign:2.1.0"
     exon            949..1080
                     /gene="Ugt2a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1081..1168
                     /gene="Ugt2a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1169..1388
                     /gene="Ugt2a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1389..2570
                     /gene="Ugt2a1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagtcctgct aacactgctg tgaagactgg gaaagtagag aaatttgttc cacattttaa
       61 gaagtctaca tcaaatcagt catgttgaag aacattttgc tctgttctct tcagataagc
      121 cttctaggaa tgagtcttgg tgggaacgtt ctcatctggc ccatggaagg cagtcactgg
      181 ctaaatgtta agatcataat agatgaactc ctaagaaaag agcataatgt gactgtcctt
      241 gtggcctccg gggccctttt catcacacca tcatccatca gcccatctct gacatttgaa
      301 atatatccag tgccctttgg caaggaaaaa attgaaagtg tgatcaaaga ctttgttttg
      361 acatggctgg aaaacaggcc atctccttca actatctgga ctttctataa ggaaatggcc
      421 aaagtcattg aggagtttca tttggtgtcc agaggtatct gtgatggcgt tcttaagaat
      481 gaaaagctga tgtccaagct tcagaaagaa aagttcgaag tactgttatc agaccctgta
      541 tttccttgtg gtgacatcgt ggctttaaaa ctgggaattc catttatcta ttccttgcgg
      601 ttttcccctg cctccacagt ggaaaagcat tgtggaaagg tcccattccc tccttcctat
      661 gtacctgcaa ttctgtcaga actcacagac cagatgtcct tcactgaccg agtaagaaac
      721 ttcatttctt accgaatgca ggactacatg tttgaaaccc tttggaagca gtgggattcc
      781 tattatacta aagctttagg aagacccacc acactgtgtg agactatggg gaaagctgag
      841 atttggctaa tgcgaaccta ttgggatttt gaatttcctc gtccatattt accgaatttt
      901 gagtttgtgg gaggactgca ctgcaaacct gccaagcctt tacctaagga aatggaagag
      961 tttgtccaga cctcagggga acatggtatt gtggtgtttt ctctggggtc aatggtcaaa
     1021 aacctgacag atgaaaaggc caatctcatt gcctcagccc ttgcccagat tcctcagaag
     1081 gttttgtggc gatacaaagg aaagatacca gacacattag gatccaatac aagactgttt
     1141 gattggattc ctcagaatga tcttcttgga catcccaaaa ccagagcttt tatcacccat
     1201 ggtggaacaa atggaatcta tgaggctatt taccatggga tccctatggt gggagtgccc
     1261 atgttcgctg accagcctga caacattgct cacatgaagg ccaaaggagc agcagtggag
     1321 gtgaacatga acacgatgac aagctcagat ctgctcaatg ctctgagaac agtcatcaat
     1381 gagccatctt ataaagagaa tgccatgaga ctatcaagaa tccaccatga ccagccagtg
     1441 aagcccctgg accgagcagt cttctggatt gagtttgtca tgcgtcacaa aggagccaag
     1501 caccttcgtg tggcagccca tgacctcagc tggtttcagt accactctct ggatgtaatt
     1561 gggtttctgc tggcctgtgt ggcatctgct atattattgg ttgcaaaatg ttgtttgttt
     1621 atatttcaaa aagttggtaa gacaggaaag aagaaaaaac gtgactagtt gaagaaaaag
     1681 acacctcagg tctctgggtt tggtgaagta ctgaagggag tagtaattgt acttagaagc
     1741 ccagggacct gcctgtcacc tatccccatt ccactttcaa acaacccact cctgtcttat
     1801 tctacaggta aattctacat aatcacactt tcctgaagac atctcatctt tcctttgcta
     1861 tttcaatgac agtttgatga cgccctggaa tttcttattt tcctggcaca ggggtactat
     1921 taatttaaat atgctatttc cagaatatca tttaaaatgt aaacaagata ataactgata
     1981 gcattctgaa tctttgagaa ggcacaaagc gtatactgag ttttatttaa ggataacaca
     2041 aggggctcat agagcacaca aatacagctc tggccacagg gattagtata gcatgagaag
     2101 agtctttatt ttctttttaa ataaaggaca gctactgtgt ttatctgatg tcaaggacat
     2161 taaagggtca gttcagaact atgaatcaat attataatag gaaaaatacg taaaaattgt
     2221 tagtacattt aaattatgat ggtctatttt cctgcttttc cctaaaatat atatctgtat
     2281 gcttgctctc ccgtcaaaga tttttagata ctttttccaa aaaattaagg caatgaactg
     2341 agttgctatt tttctcagaa aaccattact aacaatattt gaaagttatg tctagaaaga
     2401 gcaaatattg aattattgta gtaatttctt aaattttaat ggactgttct ttggctctgt
     2461 gttcatccat tatacttaaa atatttgtca ttcttaatgt ataatcacat ttataatgaa
     2521 atttttaatt ttcttctaga ataaatactt atattgggat cactgtataa aaaaaaaaaa
     2581 aaaaaaaaaa aaaaaaa
//
