LOCUS       NM_001040695            4607 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus UEV and lactate/malate dehyrogenase domains (Uevld),
            mRNA.
ACCESSION   NM_001040695
VERSION     NM_001040695.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4607)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4607)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4607)
  AUTHORS   Stefan,M., Claiborn,K.C., Stasiek,E., Chai,J.H., Ohta,T.,
            Longnecker,R., Greally,J.M. and Nicholls,R.D.
  TITLE     Genetic mapping of putative Chrna7 and Luzp2 neuronal
            transcriptional enhancers due to impact of a transgene-insertion
            and 6.8 Mb deletion in a mouse model of Prader-Willi and Angelman
            syndromes
  JOURNAL   BMC Genomics 6, 157 (2005)
   PUBMED   16280085
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB524764.1, AK155685.1 and AC090123.68.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK154536.1, AK155685.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-54                CB524764.1         10-63
            55-3736             AK155685.1         2-3683
            3737-4607           AC090123.68        53336-54206
FEATURES             Location/Qualifiers
     source          1..4607
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 30.63 cM"
     gene            1..4607
                     /gene="Uevld"
                     /gene_synonym="8430408E05Rik; Attp"
                     /note="UEV and lactate/malate dehyrogenase domains"
                     /db_xref="GeneID:54122"
                     /db_xref="MGI:MGI:1860490"
     exon            1..128
                     /gene="Uevld"
                     /gene_synonym="8430408E05Rik; Attp"
                     /inference="alignment:Splign:2.1.0"
     CDS             87..1502
                     /gene="Uevld"
                     /gene_synonym="8430408E05Rik; Attp"
                     /note="UEV-3; EV and lactate/malate dehydrogenase
                     domain-containing protein; signaling molecule ATTP"
                     /codon_start=1
                     /product="ubiquitin-conjugating enzyme E2 variant 3"
                     /protein_id="NP_001035785.1"
                     /db_xref="CCDS:CCDS39965.1"
                     /db_xref="GeneID:54122"
                     /db_xref="MGI:MGI:1860490"
                     /translation="MEFDCEGVRRLLGKYKFRDLTVEELKNVSVSFPHFRYSVDTYVF
                     KDTSQKDLLNFTGTIPVMYQGKTYNIPIRFWILDSHPFAPPICFLKPTANMEISVGKH
                     VDAKGRIYLPYLQNWSHPKSAIVGLIKEMIAKFQEELPLYSIPSSNEAQQVDLLAYIT
                     KITEGVSDINSRGWTNHENKILNKITVVGSGDLGIACTLAISAKGIADKLLLLDLSDG
                     MSQGTMDLDIFNLPNVEISKDLSASAHSKVVIFTANSLGGSESYLHAVQSNVDMFRAL
                     VPALGHYSQHAVLLVASQPVEIMSYVTWKLSTFPATRVVGIGCNLDSQRLQYIITSVL
                     KVQTSGKEVWVVGEQGENKVCSWSGRDGVLSPSSQAQLSSRAMELLKVKGQRSWSVGL
                     SVADLVDTIINNKRKVHSVSTLAKGYYGLDNEVFLSLPCILGTGGVSEVIKTKAGEDT
                     VTGTLQASASSIHALQQQLEL"
     exon            129..213
                     /gene="Uevld"
                     /gene_synonym="8430408E05Rik; Attp"
                     /inference="alignment:Splign:2.1.0"
     exon            214..279
                     /gene="Uevld"
                     /gene_synonym="8430408E05Rik; Attp"
                     /inference="alignment:Splign:2.1.0"
     exon            280..443
                     /gene="Uevld"
                     /gene_synonym="8430408E05Rik; Attp"
                     /inference="alignment:Splign:2.1.0"
     exon            444..579
                     /gene="Uevld"
                     /gene_synonym="8430408E05Rik; Attp"
                     /inference="alignment:Splign:2.1.0"
     exon            580..698
                     /gene="Uevld"
                     /gene_synonym="8430408E05Rik; Attp"
                     /inference="alignment:Splign:2.1.0"
     exon            699..801
                     /gene="Uevld"
                     /gene_synonym="8430408E05Rik; Attp"
                     /inference="alignment:Splign:2.1.0"
     exon            802..972
                     /gene="Uevld"
                     /gene_synonym="8430408E05Rik; Attp"
                     /inference="alignment:Splign:2.1.0"
     exon            973..1146
                     /gene="Uevld"
                     /gene_synonym="8430408E05Rik; Attp"
                     /inference="alignment:Splign:2.1.0"
     exon            1147..1210
                     /gene="Uevld"
                     /gene_synonym="8430408E05Rik; Attp"
                     /inference="alignment:Splign:2.1.0"
     exon            1211..1334
                     /gene="Uevld"
                     /gene_synonym="8430408E05Rik; Attp"
                     /inference="alignment:Splign:2.1.0"
     exon            1335..4607
                     /gene="Uevld"
                     /gene_synonym="8430408E05Rik; Attp"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4585..4590
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Uevld"
                     /gene_synonym="8430408E05Rik; Attp"
                     /note="hexamer: AATAAA"
     polyA_site      4607
                     /gene="Uevld"
                     /gene_synonym="8430408E05Rik; Attp"
                     /note="major polyA site"
ORIGIN      
        1 gaagtttggg cccgtgcggc ctccgttccc agcgtgtttt gaaacaagcc cagtgactgc
       61 ggccgaagaa cgcgcccctg ctgaccatgg agttcgactg tgagggcgtg agacggctgc
      121 taggcaagta caagttcagg gatctgactg tggaagagct gaagaatgtg agcgtgtctt
      181 tcccgcactt cagatactcc gtggacacct atgttttcaa agatacatcc caaaaagacc
      241 tgctgaattt caccggtaca attcctgtga tgtatcaggg taagacatac aacataccca
      301 ttcgcttctg gattttggat tcccaccctt ttgctccacc catttgcttc ttgaagccaa
      361 ctgcaaacat ggaaatctcg gttggaaaac atgtggatgc caaaggcaga atatacttgc
      421 cctatctcca aaactggagc caccccaaat ctgccatcgt tggattaatt aaagaaatga
      481 ttgccaagtt tcaagaggaa cttcctctct attccatacc gtcgtccaat gaagcgcaac
      541 aggtggactt gctggcctat atcacaaaaa tcacggaagg tgtctcagac ataaattcaa
      601 ggggctggac aaatcatgag aataaaatac tcaataaaat cactgtggtt ggaagtggag
      661 atttgggaat cgcctgcaca ttggcaattt cagcaaaggg cattgcagac aagctgctcc
      721 tcttagacct ctcagacggg atgagccaag ggacgatgga ccttgatatc ttcaacctgc
      781 ctaatgtaga gatcagcaaa gatttgtctg cctctgctca ttccaaggtg gtgatcttca
      841 cagccaactc tttgggcggt tctgaatcct atctgcatgc agtacaaagt aatgtggaca
      901 tgttcagagc tcttgttcca gctctgggac actatagtca acacgctgtc ttgcttgttg
      961 cctctcaacc agtggaaatc atgagctatg tgacgtggaa gctgagcaca tttcctgcga
     1021 ctagagtggt cgggattggc tgcaatctgg attcacagag gctgcagtac attatcacca
     1081 gtgttttgaa ggtgcagact tcaggcaaag aagtgtgggt tgttggcgaa cagggagaaa
     1141 acaaagtgtg ctcatggagt ggccgagatg gagtactgag tcccagctct caggcacagc
     1201 tatccagcag agccatggaa ctgttgaagg taaaaggtca gagatcttgg tctgttggac
     1261 tgtcagtggc tgacctggtg gatactatta taaacaataa aaggaaagtg cattctgtat
     1321 caaccttagc aaagggatat tatggtttag ataatgaagt atttttaagt ttgccatgca
     1381 tcctgggaac cggtggggta tccgaagtca tcaaaaccaa agcaggagaa gacacagtga
     1441 ctgggacact ccaggccagt gcatcctcca tccatgctct ccagcagcag ctggaactgt
     1501 gattccccag cgcagtcacc cggagatggg agcttattta attttgccaa cacacatcgt
     1561 tttgagaatt tccacaattt actctttatt cttaaaaaca gcctttctag tagatggctt
     1621 cttaattagc tttataattt gaatccttga gaatggaaaa ggattaattt cttgtaggtt
     1681 tttgacatac ctgtactgtt gtttaaacct gcaaaaggga taaatattca tttgcattgt
     1741 atttcatttt aaattacatg ttgtaaactt aaggcacatc tggcacttta gagatgttct
     1801 gtaaagattc ctgttggaca tttcttctga gtatggtgag ctgaaggcag gatgggctca
     1861 aaatctgtgc taggtgtcca ttcagagaat cttggcttca tggattaata ctgcttttgc
     1921 aagaagcagg tcatagtaat ggagaagtgt tttattttcc ttcttcaaat tcactagcta
     1981 tcaaacacta gaaagtattt tagtatgcat tttaaattgg ttaaatggaa tttttaaata
     2041 tatgaaaagt aatgtggttt aatttccact gagatttctt ttctgaaaat ttctataacc
     2101 tcttcctggg ctaaaagatc tccagtctgt cttaaaacta tattagtaga aaaagagatg
     2161 tgtcttcctg tggccgtagg taatgaataa cagccacaca gtgtattttg agaccaaaat
     2221 atgaggcttt cctaaaaacc attggtctta caggagagag gccggccggc ctgctgcttc
     2281 tccccagaag aaacccttct gactgtgcct tggtgattgg tcagtagcag tatttccatg
     2341 tgggagacag catggttggt gactgttgtg acgtgcagat ggcagcaaca gctaacacag
     2401 ctcttgtgta gcgagcactt tgtttgtaca atgcccacac taactggctg aggtagggac
     2461 tatttacctt cattacggag gtgaaaatga acgttcgtgt ctaagatcaa gtgggctcta
     2521 aggagtctca cttgcctgta taatcttttt tttaataggt agcaacaggg gttgtgggga
     2581 ggcttctgtg cctaaacgcc aagtcatcgc aagacactaa agttgagggt tgggatacta
     2641 tgaaagaatt gcttctattc tcatatgatg ggagcttctt tctttttttc ttttttgaga
     2701 cagggtctat ttgtagtctt gaccatctcg gagcttgcta ttgtagacag gctggccttg
     2761 aactcataga gaactgcctg cttctgtctc tcaatgggat taaaagtgta ggccatcata
     2821 tctgcctttt ttttttttta acaaagattg ctgagcctct tccccagaga ttccacgaac
     2881 agcagacagt gtttatgtat ttaatccttc agctagtatt tattagaaac ttctctaaca
     2941 aagcactatt agtaaacagg cccagattag gacaggccct gccaatgcct acagactagc
     3001 agggaataca gtagccaaat gtcatgtaag ttcaagagtg ctaagtgctg tgaagtccag
     3061 tgacaaggaa cccagtctag tcagagagag aggaactccg tggtttatga gacagaaagg
     3121 gaacagtctc attctcaggg tgactcgtgt aattataatg acaagtgacc ttcagtatcc
     3181 caaactggag aaagtagaaa agtaatgtgg tgacaaagac tcccaccacg tttaactgga
     3241 tgaaaccctg gacatccagg ctaggggtat agctcactgt taagatgctt gcctggcgtg
     3301 cagagccctg ggtgtggttc cagaacacag aactggggtc cttgagacga taagcatgag
     3361 ctctttgtag ataatcttgg tgttgctttt actggccttt tgtatgaagt gggaaagtaa
     3421 agttgaaaca gtcatttctt aggtgttttt ctagtatttt ctaataggtg ataactaatt
     3481 aggaactcag taattcctga ttagagcttc tttgtcttca tttggttttg agactaacct
     3541 caaagtcaac tcttagcaat catctgccta atctcctggg cattggcggc catgcccagc
     3601 aacaagtctt acattgtttg tggggatcta atccagggtc tgatgcatgt taggcaggtt
     3661 cctccccaac cctgtgtcta taatctaatc ctaaaactct cttgaacaat aaaccaactg
     3721 cagagtgctg taacaatgaa ctaccgagaa ctatgttata gaaagaaacg tcagatattt
     3781 attaaatact catcattagc caaggatttt gttagtttga cctcatcccc gggttgcagt
     3841 acagaagcct cacacttctt tgagttaagt agcaattgta cgttcctcct cagtcaggtg
     3901 gtgccatcac agccacctaa ctttgattta attattaaca gttactctat gtggtgactt
     3961 tcattttttt tctaatcatt tattggtttg gatgatgttg acttgattaa cctaaatact
     4021 gtattagtct ccaaaccaat tggaaatgta cagtgtttgc atatttctca tgtgaagcac
     4081 aaggacagga tcagaactcc tgttcattca ctaaggtgat gacctaccat atgagaaggt
     4141 tcaactctat atcaagttat aaatcctgac ttttttgtct tgttatattc tgaaatgcag
     4201 gctttgtgaa aactgaaaac tttgtaaaag atttatttct tcatttaaaa aagtactgtc
     4261 aataaaacat tgcttttcct ccttgctatg tgaaaggaaa ctttcatttt tcccaaagca
     4321 cgcggaatct caagattttt tttttaattt tttttattag gtattttcct cgtttacatt
     4381 ttcaatgcta tcccaaaggt cccccatatc caccccccca atcccctacc cacccattcc
     4441 ccctttttgg ccctgccgtt cccctgtact ggggcatcta agatttttat tgggtcttgg
     4501 attaaaatgc tttttgatac tataaaatat attttttatt ttccaattta cattgtttcc
     4561 ttaaatatca aaaataatga atgaaataaa cttttatttt aaaagga
//
