LOCUS       NM_033607               1162 bp    mRNA    linear   ROD 12-DEC-2024
DEFINITION  Mus musculus ubiquitin carboxyl-terminal esterase L4 (Uchl4), mRNA.
ACCESSION   NM_033607
VERSION     NM_033607.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1162)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1162)
  AUTHORS   Aoidi,R., Houde,N., Landry-Truchon,K., Holter,M., Jacquet,K.,
            Charron,L., Krishnaswami,S.R., Yu,B.D., Rauen,K.A., Bisson,N.,
            Newbern,J. and Charron,J.
  TITLE     Mek1Y130C mice recapitulate aspects of human cardio-facio-cutaneous
            syndrome
  JOURNAL   Dis Model Mech 11 (3) (2018)
   PUBMED   29590634
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1162)
  AUTHORS   Osawa,Y., Wang,Y.L., Osaka,H., Aoki,S. and Wada,K.
  TITLE     Cloning, expression, and mapping of a mouse gene, Uchl4, highly
            homologous to human and mouse Uchl3
  JOURNAL   Biochem Biophys Res Commun 283 (3), 627-633 (2001)
   PUBMED   11341770
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB035420.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AB035420.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1162
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 34.58 cM"
     gene            1..1162
                     /gene="Uchl4"
                     /note="ubiquitin carboxyl-terminal esterase L4"
                     /db_xref="GeneID:93841"
                     /db_xref="MGI:MGI:1890440"
     exon            1..1162
                     /gene="Uchl4"
                     /inference="alignment:Splign:2.1.0"
     CDS             39..740
                     /gene="Uchl4"
                     /EC_number="3.4.19.12"
                     /note="UCH-L4; ubiquitin thioesterase L4"
                     /codon_start=1
                     /product="ubiquitin carboxyl-terminal hydrolase isozyme
                     L4"
                     /protein_id="NP_291085.1"
                     /db_xref="CCDS:CCDS23278.1"
                     /db_xref="GeneID:93841"
                     /db_xref="MGI:MGI:1890440"
                     /translation="MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMESELLSI
                     IPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGTIG
                     LIHAIANNKDKVHFESGSTLKKFLEESVSMSPEERAKYLENYDAIRVTHETSAHEGQT
                     EAPSIDEKVDLHFIALVHVDGHLYELDGWKPFPINHGKTSDETLLEDVIKVCKKFMER
                     DPDELRFNAIALSAA"
     regulatory      843..848
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Uchl4"
                     /note="hexamer: ATTAAA"
     polyA_site      861
                     /gene="Uchl4"
                     /note="major polyA site"
ORIGIN      
        1 ggcaaggtca gagctggaga gaggccgacg gagcagtcat ggagggtcaa cgctggctgc
       61 cactggaggc caaccctgag gtcaccaacc agtttctcaa gcaattaggc ctgcatccta
      121 actggcagtt tgttgatgtg tacgggatgg agtctgaact tcttagcatc ataccaagac
      181 cagtgtgcgc agtgttactc ctcttcccta tcacagaaaa gtatgaagtc ttcagaacag
      241 aagaggaaga aaagataaaa tctcaaggac aagatgtgac atcatcagta tattttatga
      301 aacaaaccat cagcaatgcc tgtggaacga ttggaacgat tggactaatc catgccattg
      361 caaacaacaa agacaaggtg cactttgaat cagggtcaac attgaaaaag ttcctggagg
      421 agtctgtatc aatgagccct gaagagagag ccaaatacct ggagaactat gacgctattc
      481 gagttactca tgaaaccagt gcacatgaag gtcagactga ggcaccaagt atagatgaaa
      541 aagtagatct tcattttatt gcgttagtac atgtagatgg gcatctctat gaattagatg
      601 gatggaaacc atttccaatt aaccatggga aaactagcga tgagacgttg ttagaggatg
      661 tcataaaagt ttgcaagaag ttcatggaac gtgaccctga tgagttaaga tttaatgcaa
      721 ttgctctctc ggcagcatag catcttgaca gaaacaccaa atactgtatt atttgcaaca
      781 aaagttaaat ttctgatgcc ataactaact caaaattttt aatattttca ttaacttgac
      841 taattaaact ttatgtggaa acaaacaaac aaacaaacaa ggcaaaagaa actgttgtag
      901 aaggaatgtt ctagtacaag aatagcccag cagtggtggt gtataccttt aatcccagta
      961 ctcaggagac agaggcaggt ggctctccaa gttctagact agcctggtct acaaagcaag
     1021 ttccaggaca gccagcgctg catagagaaa tcctatctcg aaaaacaaaa aataaacaac
     1081 aacaacaaac aaacaaaaaa gaataataat ctgccaaagt ctctatgtta atatactatg
     1141 atacgaagcc cggtctttcc tg
//
