LOCUS       NM_025666               3247 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus ubiquitin protein ligase E3 component n-recognin 7
            (putative) (Ubr7), mRNA.
ACCESSION   NM_025666
VERSION     NM_025666.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3247)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3247)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3247)
  AUTHORS   Zimmerman,S.W., Yi,Y.J., Sutovsky,M., van Leeuwen,F.W., Conant,G.
            and Sutovsky,P.
  TITLE     Identification and characterization of RING-finger ubiquitin ligase
            UBR7 in mammalian spermatozoa
  JOURNAL   Cell Tissue Res 356 (1), 261-278 (2014)
   PUBMED   24664117
  REMARK    GeneRIF: These data provide the first evidence of ubiquitin ligase
            activity in mammalian spermatozoa and indicate UBR7 involvement in
            spermiogenesis.
REFERENCE   4  (bases 1 to 3247)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   5  (bases 1 to 3247)
  AUTHORS   Powles,N., Babbs,C., Ficker,M., Schimmang,T. and Maconochie,M.
  TITLE     Identification and analysis of genes from the mouse otic vesicle
            and their association with developmental subprocesses through in
            situ hybridization
  JOURNAL   Dev Biol 268 (1), 24-38 (2004)
   PUBMED   15031102
REFERENCE   6  (bases 1 to 3247)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK088208.1.
            
            On Apr 6, 2007 this sequence version replaced NM_025666.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK088208.1, BC094323.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3247              AK088208.1         3-3249
FEATURES             Location/Qualifiers
     source          1..3247
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="NOD"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 52.19 cM"
     gene            1..3247
                     /gene="Ubr7"
                     /gene_synonym="5730410I19Rik"
                     /note="ubiquitin protein ligase E3 component n-recognin 7
                     (putative)"
                     /db_xref="GeneID:66622"
                     /db_xref="MGI:MGI:1913872"
     exon            1..204
                     /gene="Ubr7"
                     /gene_synonym="5730410I19Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             55..1332
                     /gene="Ubr7"
                     /gene_synonym="5730410I19Rik"
                     /EC_number="2.3.2.27"
                     /note="N-recognin-7; RING-type E3 ubiquitin transferase
                     UBR7"
                     /codon_start=1
                     /product="putative E3 ubiquitin-protein ligase UBR7"
                     /protein_id="NP_079942.1"
                     /db_xref="CCDS:CCDS26124.1"
                     /db_xref="GeneID:66622"
                     /db_xref="MGI:MGI:1913872"
                     /translation="MAGAESPTECQAELEPVVSLVDVLEEDEELENEACAVLGGSDSE
                     KCSYSQGSVGRQALYACSTCTPEGEEPAGICLACSYECHGSHKLFELYTKRNFRCDCG
                     NSKFKNLECKLFPDKSKVNSCNKYNDNFFGLYCVCKRPYPDPEDEVPDEMIQCVVCED
                     WFHGRHLGAIPPESGDFQEMVCQACMRRCSFLWAYAAQLAVTRISAEDDGLLPNATGM
                     GDEDVSKPENGAPQDNGLKEDAPEHGRDSVNEVKAEQKNEPCSSSSSESDLQTVFKKE
                     NIKTEPQSSCRLQELQAKQFVKKDAATYWPLNWRSKLCTCQDCMKMYGELDVLFLTDE
                     CDTVLAYENKGKNDQATDRRDPLMDTLSSMNRVQQVELICEYNDLKTELKDYLKRFAD
                     EGTVVKREDIQQFFEEFQSKKRRRVDGLQYYCS"
     exon            205..338
                     /gene="Ubr7"
                     /gene_synonym="5730410I19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            339..399
                     /gene="Ubr7"
                     /gene_synonym="5730410I19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            400..495
                     /gene="Ubr7"
                     /gene_synonym="5730410I19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            496..549
                     /gene="Ubr7"
                     /gene_synonym="5730410I19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            550..655
                     /gene="Ubr7"
                     /gene_synonym="5730410I19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            656..864
                     /gene="Ubr7"
                     /gene_synonym="5730410I19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            865..1014
                     /gene="Ubr7"
                     /gene_synonym="5730410I19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1015..1177
                     /gene="Ubr7"
                     /gene_synonym="5730410I19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1178..1239
                     /gene="Ubr7"
                     /gene_synonym="5730410I19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1240..3247
                     /gene="Ubr7"
                     /gene_synonym="5730410I19Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cacttttccc gcctcctcct gggcccacgc agcggagccc ggtgacagtt gaggatggcc
       61 ggagccgaga gccccaccga gtgccaggcg gagctggagc ccgtggtgtc gctggtggac
      121 gtgctcgagg aagacgagga gttggagaat gaggcgtgcg ccgtcctggg cggcagcgac
      181 tcggagaagt gctcctactc gcagggctca gtggggagac aagcactgta cgcctgcagc
      241 acctgcacgc cagagggaga agagcccgca gggatttgtc tagcttgcag ttacgaatgt
      301 catggaagcc ataaactgtt tgaactatac acaaaaagaa attttcgttg tgattgtgga
      361 aacagcaagt ttaaaaactt ggaatgcaaa ttatttcctg acaaatcaaa ggtaaattct
      421 tgcaataagt acaatgacaa cttttttgga ttatactgcg tttgtaagag accttatcct
      481 gatcctgaag atgaggttcc agatgagatg atacagtgtg tggtctgtga agactggttc
      541 catggcaggc atcttggtgc cattccccct gagagtgggg atttccagga gatggtgtgc
      601 caggcttgta tgaggcgctg ttctttcttg tgggcttatg ctgcccagtt ggcagtcacc
      661 aggatatctg ctgaagatga tgggctgctg ccaaatgcta ctggcatggg agatgaagat
      721 gttagcaagc ctgaaaatgg agctccccaa gataatggcc tgaaagagga tgctcccgag
      781 catggcaggg attctgtcaa cgaggtgaaa gctgagcaga agaacgagcc ctgcagcagc
      841 tctagttctg agtctgacct ccagacagtg tttaagaaag aaaatatcaa aactgagcca
      901 cagtccagct gcagacttca ggaactccaa gccaagcagt ttgtaaagaa agatgctgcc
      961 acctattggc ccttgaactg gcgcagcaaa ctatgcacct gtcaagactg tatgaaaatg
     1021 tatggagaac tagacgtcct gttcctgaca gatgaatgtg atacagttct ggcttatgag
     1081 aacaaaggca agaacgacca ggcaactgat agaagggacc ctttaatgga cacccttagc
     1141 agcatgaata gagtccagca agtggagctc atctgtgaat acaatgactt gaagactgaa
     1201 cttaaggact acctgaagag atttgctgat gaaggcacgg ttgttaagag agaagacatt
     1261 cagcagttct ttgaagagtt tcaatcaaaa aagagaaggc gagtggacgg gttacagtat
     1321 tactgcagct aaagtggaat gccacttcct cggtcaggtt cacgaaaatg ccactgttcc
     1381 ggaataaaga gacctgtgtc acacttggtc ccctttccat cctcccgtgg cctcaggcct
     1441 tctccttaag tagctgcagg gtttctactg gtctctcagc aagcggcctc tgtgacagct
     1501 cattccacag acgtcagctc tcctgcccag gatgcccaag acttctttct gttcatggtt
     1561 tgagaagttt gatttgatct tgtgaaagca aattagcttc ttttctagca gtttgttcca
     1621 tgacttccat atgtacgctc acagagctat tgccctctgg gtcttctggg tcttgcaggg
     1681 tctcttcctg ttagcccgaa cctctgggga gcagtcccct ctgccccatg atcacggtgc
     1741 cttgggtcaa agcttcctca agcccgctct gccagtctgc tcagcgcttt ctgagattcg
     1801 atcgtggctt gaagagatgg gacttttctc tgtaccgacc ttcacggtag ccgcgactga
     1861 tgtcgtctgt gggaggttgg cttaaggcag gattgaggaa gcaagccttt gttctgaatt
     1921 tcgctgatta gtttgaagtg aaatttcatt actattctaa tggccctcca acatcagcgt
     1981 tagtactgta ctgctcccag ggcttccagg gaatctactc atgtgagccc ctttgctgct
     2041 gcctaaaaat gaccagatcc taccccctaa cgtgggtgct ttacagagtc ctctggttcc
     2101 ttacattatc agggatatgc agaaacatat attaaaaatg gacctatttt aatactgttc
     2161 tgtcaggaaa atgttattgg aacctgaata tttttcccct tgaatctgct gaaggcaagg
     2221 atactgactg accatagtgg tagtaagtgg ggcagtgaca gccctagaag atggaggatt
     2281 ccagccaaag ccctcagcta tatacatatt gagtctttgt aaaagtgcgc acagccactc
     2341 cctcctgacg gctcggaggg tcttcatgga ttgttgtata aagtcctgtg tttgagagaa
     2401 gtctttcaga tggtgtgaag tctttttaag ctccctcagt ctatgtggaa aacatctttt
     2461 gatccacaaa gacctaagtg gcaccctcca gaggaacaag gtcttcccta gtacacggtg
     2521 aggtacatta aagacatttt aggccacatg ttggtgggga tttttgtgtg tgggcagcag
     2581 ttgtatgcat gaatactcga gttccttgtc acgatgaagt agcctacaaa taaggcctca
     2641 ggaaatggca tggcttcggt actgtataca gcttgcagcc ttctagtgac agatcctggg
     2701 aagactgcta tgtggagctg caaggttctt cccgctgcag gcgaagcctg tgtgcactga
     2761 gctggcctgg atagggctca ggcagacccc cggtgcccac agcctcgggg tctcctgagc
     2821 tgaggatttg aatttgagag ttgcactttc tatgtaccag cacatcctca aaacttctct
     2881 cttcccagat gtcagattta accaccaagt tcctgtctgc ccctgatagg tcagaaccaa
     2941 ggcttagcag cagtgtcagt gagcagcaaa aatacagcca gcctatgttg aagggcttgc
     3001 ataagaaagg ttccctactt aaccagaaaa cctctttttg tacctattca caactagttt
     3061 tcttactatt ctcgtagaga tggtttgggc caacatgtgg cagttgatat taatgcatgt
     3121 tttatgcaga agaaaatgtg atactagttg cttttaagga attctggcat tgtatgtaca
     3181 tttttgtaga aattattact caatatactt caatcaggtt tctgtaaaat ccaaattaaa
     3241 cctattc
//
