LOCUS       NM_198623               2398 bp    mRNA    linear   ROD 09-JUN-2024
DEFINITION  Mus musculus ubiquilin 3 (Ubqln3), transcript variant 2, mRNA.
ACCESSION   NM_198623 XM_145822
VERSION     NM_198623.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Miyata,H., Castaneda,J.M., Fujihara,Y., Yu,Z., Archambeault,D.R.,
            Isotani,A., Kiyozumi,D., Kriseman,M.L., Mashiko,D., Matsumura,T.,
            Matzuk,R.M., Mori,M., Noda,T., Oji,A., Okabe,M.,
            Prunskaite-Hyyrylainen,R., Ramirez-Solis,R., Satouh,Y., Zhang,Q.,
            Ikawa,M. and Matzuk,M.M.
  TITLE     Genome engineering uncovers 54 evolutionarily conserved and
            testis-enriched genes that are not required for male fertility in
            mice
  JOURNAL   Proc Natl Acad Sci U S A 113 (28), 7704-7710 (2016)
   PUBMED   27357688
REFERENCE   2  (bases 1 to 2398)
  AUTHORS   Yuan,S., Qin,W., Riordan,C.R., McSwiggin,H., Zheng,H. and Yan,W.
  TITLE     Ubqln3, a testis-specific gene, is dispensable for embryonic
            development and spermatogenesis in mice
  JOURNAL   Mol Reprod Dev 82 (4), 266-267 (2015)
   PUBMED   25776854
  REMARK    GeneRIF: Ubqln3, a testis-specific gene, is dispensable for
            embryonic development and spermatogenesis in mice.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC123830.5.
            
            On Jun 3, 2020 this sequence version replaced NM_198623.2.
            
            Transcript Variant: This variant (2) uses an alternate in-frame
            splice site in the 5' coding region, compared to variant 1. This
            results in a shorter protein (isoform 2), compared to isoform 1.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-96                AC123830.5         126851-126946
            97-2398             AC123830.5         127220-129521
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 54.85 cM"
     gene            1..2398
                     /gene="Ubqln3"
                     /gene_synonym="4933400K24Rik"
                     /note="ubiquilin 3"
                     /db_xref="GeneID:244178"
                     /db_xref="MGI:MGI:3045291"
     exon            1..96
                     /gene="Ubqln3"
                     /gene_synonym="4933400K24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            97..2398
                     /gene="Ubqln3"
                     /gene_synonym="4933400K24Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             142..2118
                     /gene="Ubqln3"
                     /gene_synonym="4933400K24Rik"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /codon_start=1
                     /product="ubiquilin-3 isoform 2"
                     /protein_id="NP_941025.1"
                     /db_xref="CCDS:CCDS21610.1"
                     /db_xref="GeneID:244178"
                     /db_xref="MGI:MGI:3045291"
                     /translation="MAKSGEALPQGSLAPAQDSQLIRVTVKTPKDKEDFSVVDTCTIR
                     QLKEKISHRFKAHPNQLVLIFAGKILKDPDSLAQCGVRDGLTVHLVIKMQRRTIGTEC
                     PSPPVSIPGPNPGEIPQSSSVYSVDGSPSFSLGVLTGLSGLGLTSGSFSDQPGSLMWQ
                     HISVPELVAQLVDDPFIQGLLSNTGLVRQLVLDNPHMQHLIQQNPEIGHILNNPEIMR
                     QTMEFLRNPSMMQEMMRSQDRALSNLESIPGGYNVLRTMYTDIMDPMLNAVQEQFGGN
                     PFVTATTASTTTTSSQPSRTENCDPLPNPWTSTYGVSGGRQGRGGRQSGDQDASENRN
                     RLPSFLGNIGLFDYLQQLHETSQSLESYLQGTVPTSNPSQESPLSGNRVPPTLPSSPK
                     SGSGQSLPKESVAIKGKSSCPAFLRHSTENSTGQGGSLHDAGKGSTGPSTSLPNLTSQ
                     IGDSANRSSFVSTPSSLMSATPGVPESPWLPPTGYSRSLRSAGTNQVPRIQNEIHQQL
                     PLLLHLQTAMANPRVMQALLQIEQGLQILATEAPRLLLWFMPCLTGLNGVTGGTEARE
                     GVVMSEDPRPTPTPQISLAQGSTELGIHSSPFLQVLQALASTNPQQLQLEAHFRVQLE
                     QLRAMGFLNLEANLQALIATEGDVDAAVEKLRKS"
     regulatory      2376..2381
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ubqln3"
                     /gene_synonym="4933400K24Rik"
                     /note="hexamer: ATTACA"
     polyA_site      2398
                     /gene="Ubqln3"
                     /gene_synonym="4933400K24Rik"
                     /note="major polyA site"
ORIGIN      
        1 gagttccagc ccagaaggcc tgcagggtgg ctatacagca agatgagggc agtttggagc
       61 cctgcctaag aggaaggacg gggccacagc agattgcccc tcagctgtgt ccccacagac
      121 ctgggtctcc tgctgcccat catggccaaa agtggagagg ctctaccaca gggcagccta
      181 gcgccagccc aggattccca gctcatccgg gtgacagtga agacacccaa ggacaaggag
      241 gatttctcag ttgtagacac atgcaccatc cggcagctaa aggaaaaaat atcacaccgc
      301 tttaaggcac atccaaatca gctggtcctg atctttgctg gaaaaatcct caaggaccct
      361 gactcattgg cacagtgtgg agtgcgagat ggcctcacag tccacctggt catcaagatg
      421 cagcgtcgga ccataggcac agagtgccca tcaccaccag tctctattcc aggcccaaat
      481 cctggagaaa tccctcagtc aagttctgtt tactctgtgg atgggtctcc ttctttcagc
      541 ttaggggtcc tcacaggcct cagtgggtta ggtctgacct caggaagctt ctctgaccag
      601 ccaggctcac taatgtggca gcacatctca gtgcctgaac ttgtggctca gctcgttgat
      661 gaccccttta tccagggtct gctgtccaac acgggcctag tgcgccagtt ggttcttgac
      721 aatcctcaca tgcagcacct gatccagcag aaccctgaga ttggtcatat tcttaacaac
      781 cctgagatca tgcggcagac aatggagttt cttcgtaacc cttccatgat gcaggagatg
      841 atgcgtagcc aggatcgtgc actcagtaac ctggagagca tccctggtgg ctacaatgtg
      901 ctccgtacta tgtacacaga tattatggat cccatgctta atgcagtaca ggaacaattt
      961 ggtggcaatc cttttgtcac tgctactact gctagtacca ccaccaccag cagccaacca
     1021 tcaaggacag agaattgtga ccctctgccc aacccctgga cttccacata tggggtctca
     1081 ggtggaagac aaggaagagg tggcagacag tctggggacc aggatgcatc tgaaaataga
     1141 aataggcttc caagctttct gggtaacata ggactctttg attatcttca acagttacat
     1201 gagacttctc agtccctgga atcttatctg cagggtactg tgccaacttc aaatccaagc
     1261 caggaatcac cactttcagg aaacagagtt cctccaactt taccatcatc ccctaaatct
     1321 gggtcaggcc aatctctgcc caaagagtca gtagcaatca agggaaagtc atcatgccca
     1381 gctttcttga gacactcaac tgagaacagt actggacaag gtggaagcct acatgatgca
     1441 gggaagggct ctactggccc cagtactagc ttgcccaatc ttacctctca gataggagat
     1501 tctgccaaca gatcctcgtt tgtttctaca ccatcttccc ttatgtcagc tactcctgga
     1561 gtcccagaat ctccctggct tcctccaaca ggttactcaa gatctctgag atcagcgggc
     1621 acaaatcaag tccctcgaat ccagaatgag atacatcaac agctaccact actgttgcat
     1681 cttcagacag ccatggcaaa tccccgtgtc atgcaagcct tgctgcagat tgagcagggt
     1741 ctacagattc tggctactga agcaccccgc ctcctgctct ggttcatgcc ctgcctaaca
     1801 gggttgaatg gagtaacagg aggcacagaa gctagagaag gtgttgttat gtctgaggat
     1861 ccccgaccaa ccccaactcc tcagatttct ctagcacaag gttctacaga gctaggtatc
     1921 cattcctccc ccttcctcca ggtgttacaa gccttagcta gtaccaatcc ccagcagcta
     1981 caactggagg ctcacttccg ggtacaactg gagcaactgc gggctatggg ctttctgaat
     2041 cttgaagcca atctccaggc cctcattgct acagagggtg atgtagatgc tgctgtggag
     2101 aaattgagga agtcttagga gctctagtta tttggaccat atcttttcct ttctgccttt
     2161 cccccatgtc ttattaccct agttctccta ttcttgaata cagctgcact ataaaccaaa
     2221 ttactatgat gttctttact gtggagacaa tgttctggag tcaataagga agatgagaag
     2281 ccagaaatag ggtggggatg ctgtgtaatc caactgtgcc tgacactctt ttacctgggg
     2341 cccttgaatg agttctgtac ctatcttgag atgcaattac atccagtctt tagtgcca
//
